Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of NrdR regulog to Lactobacillus plantarum WCFS1

Reference regulog properties
Source regulog: NrdR - Lactobacillaceae
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Deoxyribonucleotide biosynthesis
Effector: Deoxyribonucleotides
Phylum: Firmicutes
Propagated regulon:
Target genome Lactobacillus plantarum WCFS1
Orthologous TF(s) lp_1511
Regulated genes 4
Built upon 81 sites [see more]
Predicted regulatory interactions in Lactobacillus plantarum WCFS1
Locus tag Position Score Sequence
Position: -86
Score: 4.6
Sequence: ACCCTAGATGTTGTGT
Position: -54
Score: 4.7
Sequence: TCACCACATGTTGTAT
Locus tag: lp_0694
lp_0694 -86 4.6 ACCCTAGATGTTGTGT
-54 4.7 TCACCACATGTTGTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdH
Ortholog function: Glutaredoxin-like protein NrdH
Lactobacillus plantarum WCFS1 lp_0694 -86 4.6 ACCCTAGATGTTGTGT
-54 4.7 TCACCACATGTTGTAT
Pediococcus pentosaceus ATCC 25745 PEPE_1487 -122 5.3 GCACAATATATAGTGG
Position: -99
Score: 4.4
Sequence: TCACCAGATATTGCAT
Position: -67
Score: 5
Sequence: GTACAATATGTAGTGT
Locus tag: lp_1011
lp_1011 -99 4.4 TCACCAGATATTGCAT
-67 5 GTACAATATGTAGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: dgk1
Ortholog function: Deoxyadenosine kinase (EC 2.7.1.76) / Deoxyguanosine kinase (EC 2.7.1.113)
Lactobacillus brevis ATCC 367 LVIS_1711 -100 4.8 CCACGATATATTGTCT
-68 4.9 GTACAATATGTGGTGT
Lactobacillus plantarum WCFS1 lp_1011 -99 4.4 TCACCAGATATTGCAT
-67 5 GTACAATATGTAGTGT
Pediococcus pentosaceus ATCC 25745 PEPE_1437 -77 4.1 TTTCAAGATATTGTTT
-46 4.4 GTACAATATGTAGTGC
Position: -40
Score: 5.1
Sequence: ATACAATATATTGTGC
Locus tag: lp_1329
lp_1329 -40 5.1 ATACAATATATTGTGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: dgk2
Ortholog function: Deoxyadenosine kinase (EC 2.7.1.76) / Deoxyguanosine kinase (EC 2.7.1.113)
Lactobacillus brevis ATCC 367 LVIS_1520 -41 3.6 GTACACTATATCTTGT
-39 5.7 ACACTATATCTTGTAT
Lactobacillus plantarum WCFS1 lp_1329 -72 3.9 AAAGTCTATATGGTAT
-40 5.1 ATACAATATATTGTGC
Lactobacillus reuteri JCM 1112 LAR_1221 -88 4.4 CCACCAAATATTGTAA
-56 5 CCACAATATTTTGTAG
Pediococcus pentosaceus ATCC 25745 PEPE_0650 -83 5.2 ATACAATATGTTGTGG
Position: -80
Score: 5.5
Sequence: CTACTATATATAGTAT
Locus tag: lp_2932
lp_2932 -80 5.5 CTACTATATATAGTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdD
Ortholog function: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Lactobacillus acidophilus NCFM LBA0160 -58 4.5 ATACAAGATGTTGTGC
Lactobacillus casei ATCC 334 LSEI_0131 -133 5 ACACACTATATAGTGT
-131 5.5 ACACTATATAGTGTAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0185 -173 5.3 CCACAATATCTGGTAT
-131 4.6 AAACAAGATGTAGTGG
Lactobacillus fermentum IFO 3956 LAF_1376 -99 4.7 CCACAAGATCTTGTAA
-68 5.3 AAACTATATGTTGTGT
Lactobacillus helveticus DPC 4571 lhv_0169 -56 5.1 ATACAAGATGTTGTAT
Lactobacillus johnsonii NCC 533 LJ0137 -63 4.6 CTACAATATCATGTAG
Lactobacillus plantarum WCFS1 lp_2932 -80 5.5 CTACTATATATAGTAT
-49 4.4 GCACTATCAATTGTAT
Lactobacillus reuteri JCM 1112 LAR_1249 -92 5.3 CCACAACATATAGTGT
Lactobacillus rhamnosus GG LGG_00138 -131 5.5 CCACTATATAGTGTAT
Lactobacillus sakei subsp. sakei 23K LSA1459 -75 5.1 ACACTATATATAGTTG
Lactobacillus salivarius subsp. salivarius UCC118 LSL_1332 -108 5.5 ATACTATATATAGTGT
-76 5.9 ACACTATATATTGTAT
Pediococcus pentosaceus ATCC 25745 PEPE_0484 -133 5.7 ATACTATATATTGTAT
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