Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of NrdR regulog to Lactobacillus reuteri 100-23

Reference regulog properties
Source regulog: NrdR - Lactobacillaceae
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Deoxyribonucleotide biosynthesis
Effector: Deoxyribonucleotides
Phylum: Firmicutes
Propagated regulon:
Target genome Lactobacillus reuteri 100-23
Orthologous TF(s) Lreu23DRAFT_0048
Regulated genes 4
Built upon 81 sites [see more]
Predicted regulatory interactions in Lactobacillus reuteri 100-23
Locus tag Position Score Sequence
Position: -72
Score: 5.6
Sequence: CCACAATATCTTGTGT
Locus tag: Lreu23DRAFT_1873
Lreu23DRAFT_1873 -72 5.6 CCACAATATCTTGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pnuN
Ortholog function: NrdR-regulated deoxyribonucleotide transporter, PnuC-like
Lactobacillus acidophilus NCFM LBA1653 -53 5.5 GCACAATATATAGTAT
Lactobacillus brevis ATCC 367 LVIS_0311 -82 5.8 CCACAATATATTGTGT
-41 3.5 GTACTAAATATAGAAA
Lactobacillus casei ATCC 334 LSEI_1204 -107 4.9 CACCAATATATTGTAT
-105 3.6 CCAATATATTGTATAT
Lactobacillus helveticus DPC 4571 lhv_1757 -172 3.7 ACACAACATATAGATA
-140 4.5 GCACAATATTTTGTAA
-50 4.9 ACACAAAATGTTGTAT
Lactobacillus johnsonii NCC 533 LJ0643 -46 5.7 GCACAATATATTGTGT
Lactobacillus plantarum WCFS1 lp_0259 -108 5.7 ATACAATATATTGTGT
-78 4.8 ACACTACATGTAGTAG
Lactobacillus reuteri JCM 1112 LAR_1670 -72 5.6 CCACAATATCTTGTGT
-30 4.9 GCACAACATATAGTAG
Lactobacillus rhamnosus GG LGG_01221 -139 3.9 TTAGTACATGTTGTGG
-107 4.9 CACCAATATATTGTAT
Lactobacillus sakei subsp. sakei 23K LSA1189 -155 4.2 CTACCATATTTTGAAT
-105 5.4 GTACTATATATAGTGT
Position: -121
Score: 5.6
Sequence: GTACTATATATTGTGT
Locus tag: Lreu23DRAFT_1290
Lreu23DRAFT_1290 -121 5.6 GTACTATATATTGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdH
Ortholog function: Glutaredoxin-like protein NrdH
Lactobacillus reuteri JCM 1112 LAR_0313 -115 5.6 GTACTATATATTGTGT
Position: -92
Score: 5.3
Sequence: CCACAACATATAGTGT
Locus tag: Lreu23DRAFT_1449
Lreu23DRAFT_1449 -92 5.3 CCACAACATATAGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdD
Ortholog function: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Lactobacillus acidophilus NCFM LBA0160 -58 4.5 ATACAAGATGTTGTGC
Lactobacillus casei ATCC 334 LSEI_0131 -133 5 ACACACTATATAGTGT
-131 5.5 ACACTATATAGTGTAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 LBUL_0185 -173 5.3 CCACAATATCTGGTAT
-131 4.6 AAACAAGATGTAGTGG
Lactobacillus fermentum IFO 3956 LAF_1376 -99 4.7 CCACAAGATCTTGTAA
-68 5.3 AAACTATATGTTGTGT
Lactobacillus helveticus DPC 4571 lhv_0169 -56 5.1 ATACAAGATGTTGTAT
Lactobacillus johnsonii NCC 533 LJ0137 -63 4.6 CTACAATATCATGTAG
Lactobacillus plantarum WCFS1 lp_2932 -80 5.5 CTACTATATATAGTAT
-49 4.4 GCACTATCAATTGTAT
Lactobacillus reuteri JCM 1112 LAR_1249 -92 5.3 CCACAACATATAGTGT
Lactobacillus rhamnosus GG LGG_00138 -131 5.5 CCACTATATAGTGTAT
Lactobacillus sakei subsp. sakei 23K LSA1459 -75 5.1 ACACTATATATAGTTG
Lactobacillus salivarius subsp. salivarius UCC118 LSL_1332 -108 5.5 ATACTATATATAGTGT
-76 5.9 ACACTATATATTGTAT
Pediococcus pentosaceus ATCC 25745 PEPE_0484 -133 5.7 ATACTATATATTGTAT
Position: -56
Score: 5
Sequence: CCACAATATTTTGTAG
Locus tag: Lreu23DRAFT_0799
Lreu23DRAFT_0799 -56 5 CCACAATATTTTGTAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: dgk2
Ortholog function: Deoxyadenosine kinase (EC 2.7.1.76) / Deoxyguanosine kinase (EC 2.7.1.113)
Lactobacillus brevis ATCC 367 LVIS_1520 -41 3.6 GTACACTATATCTTGT
-39 5.7 ACACTATATCTTGTAT
Lactobacillus plantarum WCFS1 lp_1329 -72 3.9 AAAGTCTATATGGTAT
-40 5.1 ATACAATATATTGTGC
Lactobacillus reuteri JCM 1112 LAR_1221 -88 4.4 CCACCAAATATTGTAA
-56 5 CCACAATATTTTGTAG
Pediococcus pentosaceus ATCC 25745 PEPE_0650 -83 5.2 ATACAATATGTTGTGG
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