Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Shigella dysenteriae Sd197

Type Regulator Effector Pathway Genes Sites
TF AcrR Rhodamine 6G; Ethidium bromide; Proflavin Multidrug resistance 2 2
TF AraC Arabinose Arabinose utilization 1 2
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 12 28
TF AscG Cellobiose-6-phosphate; Beta-glucoside-6-phosphate Beta-glucosides utilization; Cellobiose utilization 1 1
TF BirA Biotin Biotin biosynthesis 2 2
TF Crp Cyclic 3',5'-AMP Carbon catabolism 215 554
TF CueR Copper ion, (Cu+) Copper resistance 1 1
TF DeoR Deoxyribonucleoside utilization 2 3
TF EbgR Beta-galactosides Galactosides utilization 1 1
TF ExuR Galacturonate Galacturonate utilization 2 2
TF FabR Unsaturated acyl-ACP; Unsaturated acyl-CoA Fatty acid biosynthesis 2 2
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 9 13
TF Fnr Oxygen Energy metabolism; Anaerobic metabolism 93 170
TF FruR Fructose-1-phosphate; Fructose-1,6-diphosphate Central carbohydrate metabolism 22 26
TF FucR L-fuculose-1-phosphate Fucose utilization 1 2
TF Fur Iron ion, (Fe2+) Iron homeostasis 32 93
TF GalR/GalS Galactose Galactose utilization 4 5
TF GcvA Glycine Glycine metabolism 2 2
TF GlpR Glycerol 3-phosphate Glycerol utilization 5 7
TF GntR Gluconate Gluconate utilization 3 6
TF HexR 2-keto-3-deoxy-6-phosphogluconate Central carbohydrate metabolism 3 3
TF IlvY 2-Acetolactate Branched-chain amino acid biosynthesis 2 4
TF IscR Iron-sulfur cluster redox state Iron-sulfur cluster biogenesis 2 3
TF KdgR 2-keto-3-deoxygluconate Pectin and polygalacturonate utlization 9 11
TF LacI Allolactose Lactose utilization 1 1
TF LexA DNA damage SOS response 19 23
TF LldR L-lactate Lactate utilization 1 1
TF LysR LL-2,6-Diaminopimelate Lysine biosynthesis 2 2
TF MalI Maltose utilization 2 3
TF MarR Salicylate; Tetracycline; Chloramphenicol Antibiotic resistance 1 1
TF MetR Homocysteine Methionine biosynthesis 6 9
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 5 5
TF ModE Molybdate Molybdopterin biosynthesis; Molybdenum homeostasis 5 5
TF MprA 2,4-Dinitrophenol; Carbonyl cyanide m-chlorophenylhydrazone Multidrug resistance 2 2
TF MurR N-acetylmuramate-6-phosphate N-acetylmuramate utilization 2 2
TF NadR NAD NAD biosynthesis 3 3
TF NagC N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 5 7
TF NarP Nitrate; Nitrite Nitrate and nitrite respiration 19 21
TF NhaR Potassium ion Osmotic stress response 1 1
TF NikR Nickel ion, (Ni2+) Nickel homeostasis 1 1
TF NorR Nitric oxide Nitrosative stress response 2 2
TF NrdR Deoxyribonucleotides Ribonucleotide reductases 3 7
TF NsrR Nitric oxide Nitrosative stress response 8 12
TF NtrC Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 12 22
TF PdhR Pyruvate Pyruvate metabolism 3 4
TF PhnF Phosphonate utilization 1 1
TF PurR Hypoxanthine; Guanine Purine metabolism 23 29
TF QorR Energy metabolism 1 1
TF RhaR Rhamnose Rhamnose utilization 2 2
TF RhaS Rhamnose Rhamnose utilization 3 3
TF RutR Uracil Pyrimidine utilization 3 3
TF SdaR Glycerate Glucarate utilization; Galactarate utilization 1 1
TF SorC Sorbose Sorbose utilization 1 1
TF SoxR Paraquat Superoxide stress response 2 2
TF TreR Trehalose-6-phosphate Trehalose utilization 1 1
TF TrpR Tryptophan Tryptophan biosynthesis 3 3
TF TyrR Tyrosine; Phenylalanine Aromatic amino acid metabolism 9 16
TF UlaR Ascorbate-6-phosphate Ascorbate utilization 2 3
TF UxuR Glucuronate Glucuronate utilization 3 3
TF ZntR Zinc ion, (Zn2+) Zinc resistance 1 1
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 4 4
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