Propagated regulons of Streptococcus gallolyticus UCN34
|
Type |
Regulator |
Effector |
Pathway |
Genes |
Sites |
TF |
AdcR |
Zinc ion, (Zn2+) |
Zinc homeostasis |
3 |
4 |
TF |
ArgR |
Arginine |
Arginine biosynthesis; Arginine degradation |
7 |
15 |
TF |
BirA |
Biotin |
Biotin biosynthesis |
3 |
3 |
TF |
CcpA |
Fructose-1,6-bisphosphate; HPr, phosphocarrier protein |
Global catabolite repression |
67 |
106 |
TF |
CcpB |
|
Sugar utilization |
1 |
1 |
TF |
CelR |
CelB, cellobiose-specific PTS component EIIB; HPr, phosphocarrier protein |
Cellobiose utilization |
2 |
2 |
TF |
CmbR |
O-acetyl-L-serine |
Cysteine metabolism |
11 |
17 |
TF |
CodY |
Guanosine triphosphate; Branched-chain amino acids |
Amino acid metabolism |
32 |
42 |
TF |
CopR |
Copper ion, (Cu2+) |
Copper homeostasis |
1 |
2 |
TF |
CtsR |
Heat shock |
Heat shock response |
4 |
4 |
TF |
FabT |
Long-chain acyl-ACP |
Fatty acid biosynthesis |
3 |
6 |
TF |
FruR |
Fructose-6-phosphate |
Fructose utilization |
1 |
4 |
TF |
GalR |
Galactose |
Galactose utilization |
3 |
5 |
TF |
GlnR |
Phosphorylated NtrB, signal histidine kinase |
Nitrogen assimilation |
7 |
8 |
TF |
HomR |
O-acetyl-L-serine |
Methionine metabolism; Cysteine metabolism |
4 |
4 |
TF |
HrcA |
Heat shock |
Heat shock response |
2 |
3 |
TF |
LacR |
D-galactose-6-phosphate |
Lactose utilization; Galactose utilization |
4 |
33 |
TF |
MalR |
Maltose |
Maltose utilization; Maltodextrin utilization |
7 |
8 |
TF |
MleR |
L-malate |
Malate utilization |
2 |
2 |
TF |
MntR |
Manganese ion, (Mn2+) |
Manganese homeostasis |
2 |
2 |
TF |
MtaR |
Homocysteine |
Methionine metabolism |
7 |
10 |
TF |
MtlR |
MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein |
Mannitol utilization |
1 |
1 |
TF |
NagR |
N-acetylglucosamine-6-phosphate |
N-acetylglucosamine utilization |
3 |
6 |
TF |
NiaR |
Niacin |
NAD biosynthesis |
3 |
4 |
TF |
NmlR |
Methylglyoxal; Formaldehyde; Nitric oxide |
Carbonyl stress response |
2 |
2 |
TF |
NrdR |
Deoxyribonucleotides |
Deoxyribonucleotide biosynthesis |
2 |
4 |
TF |
PadR |
Ferulic acid; p-Coumaric acid |
Phenolic acid stress response |
1 |
1 |
TF |
PerR |
Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide |
Iron homeostasis; Manganese homeostasis; Oxidative stress response |
7 |
9 |
TF |
PipR |
|
Phage infection protein |
2 |
4 |
TF |
PurR |
5-phosphoribosyl 1-pyrophosphate |
Purine metabolism |
7 |
17 |
TF |
Rex |
NADH |
Energy metabolism |
10 |
19 |
TF |
Rgg |
|
Cell wall metabolism |
3 |
4 |
TF |
SAG1910 |
|
unknown |
1 |
1 |
TF |
ScrR |
Sucrose-6-phosphate |
Sucrose utilization |
2 |
2 |
TF |
SgaR |
HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component |
Ascorbate utilization |
2 |
2 |
TF |
SPy1285 |
|
Transport |
2 |
2 |
TF |
TreR |
Trehalose-6-phosphate |
Trehalose utilization |
2 |
2 |
TF |
YjdR |
|
Multidrug resistance |
1 |
1 |
TF |
YwzG |
|
Transport |
1 |
2 |