Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Streptococcus pneumoniae JJA

Type Regulator Effector Pathway Genes Sites
TF AdcR Zinc ion, (Zn2+) Zinc homeostasis 5 6
TF AgaR N-acetylgalactosamine N-acetylgalactosamine utilization 2 2
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 11 16
TF BfrR Fructooligosaccharides utilization 1 2
TF BirA Biotin Biotin biosynthesis 1 2
TF CcpA Fructose-1,6-bisphosphate; HPr, phosphocarrier protein Global catabolite repression 85 113
TF CmbR O-acetyl-L-serine Cysteine metabolism 6 10
TF CodY Guanosine triphosphate; Branched-chain amino acids Amino acid metabolism 21 24
TF CopR Copper ion, (Cu2+) Copper homeostasis 1 2
TF CtsR Heat shock Heat shock response 4 4
TF FabT Long-chain acyl-ACP Fatty acid biosynthesis 3 4
TF FruR Fructose-6-phosphate Fructose utilization 1 4
TF FucR L-fuculose-1-phosphate Fucose utilization 2 2
TF GalR Galactose Galactose utilization 2 4
TF GlnR Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 4 4
TF HomR O-acetyl-L-serine Methionine metabolism; Cysteine metabolism 2 3
TF HrcA Heat shock Heat shock response 2 3
TF LacR D-galactose-6-phosphate Lactose utilization; Galactose utilization 3 15
TF MalR Maltose Maltose utilization; Maltodextrin utilization 7 7
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 2 2
TF MtaR Homocysteine Methionine metabolism 6 6
TF MtlR MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein Mannitol utilization 1 1
TF NagR N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 3 5
TF NanR N-acetylneuraminic acid Sialic acid utilization 3 3
TF NiaR Niacin NAD biosynthesis 2 3
TF NmlR Methylglyoxal; Formaldehyde; Nitric oxide Carbonyl stress response 1 1
TF NrdR Deoxyribonucleotides Deoxyribonucleotide biosynthesis 2 4
TF PerR Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide Iron homeostasis; Manganese homeostasis; Oxidative stress response 2 2
TF PflR Formate metabolism 3 3
TF PipR Phage infection protein 2 4
TF PurR 5-phosphoribosyl 1-pyrophosphate Purine metabolism 9 13
TF RegR Hyaluronate oligosaccharide phosphate Hyaluronate utilization 3 5
TF Rex NADH Energy metabolism 13 22
TF ScrR Sucrose-6-phosphate Sucrose utilization 1 1
TF SczA Zinc ion, (Zn2+) Zinc resistance 2 2
TF SgaR HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component Ascorbate utilization 1 1
TF SgaR2 SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein Ascorbate utilization 1 1
TF SPy1285 Transport 2 2
TF TreR Trehalose-6-phosphate Trehalose utilization 2 2
TF YwzG Transport 1 2
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