Propagation of CmbR regulog to Streptococcus pneumoniae JJA
| Source regulog: | CmbR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | LysR |
| Regulation mode: | repressor (activator) |
| Biological process: | Cysteine metabolism |
| Effector: | O-acetyl-L-serine |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus pneumoniae JJA |
| Orthologous TF(s) | SPJ_0867, SPJ_0627 |
| Regulated genes | 6 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -99
Score: 5.5 Sequence: GTCATAAAGAAAACTTATCAC
Locus tag: SPJ_0177
|
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| SPJ_0177 | -99 | 5.5 | GTCATAAAGAAAACTTATCAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gshT | ||||
| Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein | ||||
| Streptococcus mitis B6 | smi_1946 | -99 | 5.1 | GCCATAAAGAAAACCTATCAC |
| Streptococcus pneumoniae TIGR4 | SP_0148 | -99 | 5.3 | CCCATAAAAAAAACTTATCAC |
|
Position: -251
Score: 4.5 Sequence: GTTATAGTCTTTTCTAATAAC
Position: -218
Score: 4.9 Sequence: CTTATAAGAATTACTAATAAC
Locus tag: SPJ_0540
|
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| SPJ_0540 | -251 | 4.5 | GTTATAGTCTTTTCTAATAAC | |
| -218 | 4.9 | CTTATAAGAATTACTAATAAC | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metE | ||||
| Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1368 | -39 | 4.7 | TTGATAAGATAGACCTATTAA |
| Lactococcus lactis subsp. lactis Il1403 | L0100 | -76 | 4.1 | ATCATATTAAAAATGTATTAT |
| -39 | 4.7 | TTGATAAGATAGACCTATTAA | ||
| Streptococcus agalactiae 2603V/R | SAG2049 | -109 | 4.1 | GCTAAAAATATAAAATATTAA |
| Streptococcus gallolyticus UCN34 | GALLO_1316 | -221 | 4.2 | ATAATAAATTTTATTAATCTA |
| -172 | 4.6 | GTTATAGTTAAAAACTATAAT | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0310 | -182 | 4.2 | GTTATAGTTTTTGATTATACC |
| Streptococcus mutans UA159 | SMU.873 | -188 | 4.6 | GTTATAGATGAAAACTATAAC |
| Streptococcus pneumoniae TIGR4 | SP_0585 | -218 | 4.9 | CTTATAAGAATTACTAATAAC |
| Streptococcus sanguinis SK36 | SSA_0416 | -182 | 4.3 | GTCATAATTTCTACCTATAGC |
| Streptococcus suis 05ZYH33 | SSU05_1774 | -237 | 4.3 | TTCATAGATAAAATCTATACC |
| Streptococcus thermophilus CNRZ1066 | str0785 | -119 | 4.2 | GCTATACAAATATCTAATTAA |
|
Position: -100
Score: 4.9 Sequence: ATGATTAAGTTTTTCTATCAC
Locus tag: SPJ_0572
|
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| SPJ_0572 | -100 | 4.9 | ATGATTAAGTTTTTCTATCAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gshT | ||||
| Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1847 | -98 | 5.2 | GTGATAAAAAAAATCTATTGG |
| -61 | 5 | AGGATAGAATAATCTTATCAC | ||
| Streptococcus mitis B6 | smi_1579 | -101 | 5.1 | ATGATTAAGTTTTTTTATCAC |
| Streptococcus pneumoniae TIGR4 | SP_0620 | -100 | 4.9 | ATGATTAAGTTTTTCTATCAC |
| Streptococcus thermophilus CNRZ1066 | str0908 | -101 | 5.2 | TTGATAGATATTGTTTATCAG |
|
Position: -142
Score: 5.2 Sequence: TTGATAGATAAAATATATAAC
Locus tag: SPJ_1360
|
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| SPJ_1360 | -142 | 5.2 | TTGATAGATAAAATATATAAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: tcyB | ||||
| Ortholog function: Cystine ABC transporter, permease protein | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1010 | -77 | 5.1 | GCTATAAGTTTTTTTTATGGC |
| Lactococcus lactis subsp. lactis Il1403 | L163056 | -77 | 5.1 | GCTATAAGTTTTTTTTATGGC |
| Streptococcus agalactiae 2603V/R | SAG0291 | -96 | 5.5 | TTGATATAAAATCTTTATCAC |
| -75 | 4.7 | CTGATAAGGAAATACTATTAT | ||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1719 | -99 | 5.3 | GTGATAAGTTTTGCTTATTGC |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1580 | -106 | 5 | GCGATAGGCTTTTCTTATCGT |
| Streptococcus gallolyticus UCN34 | GALLO_0415 | -100 | 5.2 | CTGATAGTTTTTTCTTATCAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0578 | -170 | 4.7 | GTCATAAAATTTGCTTATACC |
| -148 | 4.3 | TTGATAAATAATTTATACTGT | ||
| Streptococcus mitis B6 | smi_1382 | -164 | 4.7 | GAGATAGTTTTTACTTATCTC |
| -142 | 5 | TTGATAGATAAAATATATAGC | ||
| Streptococcus mutans UA159 | SMU.460 | -102 | 5.8 | GTGATAGAAAAATATTATCAC |
| -80 | 5 | GTGATAGGAAAAAACTATTAT | ||
| Streptococcus pneumoniae TIGR4 | SP_1461 | -164 | 4.3 | GAAATAGTTTTTATCTATCTC |
| -142 | 5.2 | TTGATAGATAAAATATATAAC | ||
| Streptococcus sanguinis SK36 | SSA_1868 | -250 | 5.4 | GTGATATACTTTTCTTATCGC |
| -228 | 5.3 | GTGATAAGAAAAATATATTAG | ||
| Streptococcus thermophilus CNRZ1066 | str1653 | -217 | 5.8 | GTGATATGATTTACTTATCAC |
| Streptococcus uberis 0140J | SUB1415 | -80 | 4.8 | GTGATAGGCTTTAACTATTGC |
|
Position: -103
Score: 5.2 Sequence: TCCATAAAAAATGTTTATCAC
Locus tag: SPJ_2094
|
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| SPJ_2094 | -103 | 5.2 | TCCATAAAAAATGTTTATCAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: yvdE | ||||
| Ortholog function: Predicted glutamine amidotransferase, class I | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1848 | -98 | 5.2 | GTGATAAAAAAAATCTATTGG |
| -61 | 5 | AGGATAGAATAATCTTATCAC | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0167 | -97 | 5.5 | TTGATAAAAAATTTTTATAAG |
| Streptococcus pneumoniae TIGR4 | SP_2072 | -64 | 5.2 | TCCATAAAAAATGTTTATCAC |
| Streptococcus sanguinis SK36 | SSA_2164 | -100 | 5.8 | CTGATAAAAAATTTTTATAAC |
| Streptococcus suis 05ZYH33 | SSU05_1773 | -95 | 5.3 | CTGATAGTTATTTTTTATCAA |
|
Position: -98
Score: 4.6 Sequence: GATATATAGAAATCCTATCGC
Locus tag: SPJ_2236
|
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| SPJ_2236 | -98 | 4.6 | GATATATAGAAATCCTATCGC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysK | ||||
| Ortholog function: Cysteine synthase (EC 2.5.1.47) | ||||
| Lactococcus lactis subsp. lactis Il1403 | L0089 | -79 | 5.3 | GCTATAAAAAAATCTTATAGC |
| Lactococcus lactis subsp. lactis Il1403 | L0088 | -87 | 4.5 | ATCATAAATTTTTTTTAGAGC |
| Streptococcus mitis B6 | smi_2060 | -98 | 5.3 | GATATAAAAAAATCCTATCAC |
| Streptococcus thermophilus CNRZ1066 | str0366 | -16 | 5.2 | ATGATAAAATTTTTTTATGGA |
| Streptococcus uberis 0140J | SUB1379 | -104 | 5.1 | ATGATAAGCCTTTCCTATCAC |