Regulon of PurR in Macrococcus caseolyticus JCSC5402

Properties
Regulator type:	Transcription factor
TF locus tag:	MCCL_1916, MCCL_1917
Regulator family:	PurR
Regulation mode:	repressor
Biological process:	Purine metabolism
Effector:	5-phosphoribosyl 1-pyrophosphate
Regulog:	PurR - Staphylococcaceae
Statistics of regulated genes:
- Genes	14
- Operons	4
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 26 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - PurR
By effector - 5-phosphoribosyl 1-pyrophosphate
By pathway - Purine metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -193 Score: 7.4 Sequence: AAAATACGAACGAA-(18)-AAAATACGTAATTG Locus tag: MCCL_0687 Name: purE Funciton: phosphoribosylaminoimidazole carboxylase catalytic subunit Locus tag: MCCL_0688 Name: purK Funciton: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) Locus tag: MCCL_0689 Name: purC Funciton: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) Locus tag: MCCL_0690 Name: purS Funciton: phosphoribosylformylglycinamidine synthase, PurS protein Locus tag: MCCL_0691 Name: purQ Funciton: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) Locus tag: MCCL_0692 Name: purL Funciton: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) Locus tag: MCCL_0693 Name: purF Funciton: amidophosphoribosyltransferase (EC:2.4.2.14) Locus tag: MCCL_0694 Name: purM Funciton: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) Locus tag: MCCL_0695 Name: purN Funciton: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) Locus tag: MCCL_0696 Name: purH Funciton: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) Locus tag: MCCL_0697 Name: purD Funciton: phosphoribosylamine--glycine ligase (EC:6.3.4.13)
	MCCL_0687	purE	phosphoribosylaminoimidazole carboxylase catalytic subunit
	MCCL_0688	purK	phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21)
	MCCL_0689	purC	phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6)
	MCCL_0690	purS	phosphoribosylformylglycinamidine synthase, PurS protein
	MCCL_0691	purQ	phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3)
	MCCL_0692	purL	phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3)
	MCCL_0693	purF	amidophosphoribosyltransferase (EC:2.4.2.14)
	MCCL_0694	purM	phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
	MCCL_0695	purN	phosphoribosylglycinamide formyltransferase (EC:2.1.2.2)
	MCCL_0696	purH	phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10)
	MCCL_0697	purD	phosphoribosylamine--glycine ligase (EC:6.3.4.13)
Position: -97 Score: 9 Sequence: AATACACGAACTTT-(18)-AATGTACGGAATTT Locus tag: MCCL_1646 Name: null Funciton: adenylosuccinate lyase (EC:4.3.2.2)
	MCCL_1646		adenylosuccinate lyase (EC:4.3.2.2)
Position: -299 Score: 8 Sequence: AAAAACCGTACATT-(18)-ATTGTACGGTTTTT Locus tag: MCCL_0019 Name: purA Funciton: adenylosuccinate synthase (EC:6.3.4.4)
	MCCL_0019	purA	adenylosuccinate synthase (EC:6.3.4.4)
Position: -101 Score: 7.4 Sequence: CAATTACGTATTTT-(18)-TTCGTTCGTATTTT Locus tag: MCCL_0686 Name: folD Funciton: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9)
	MCCL_0686	folD	methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9)

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