Regulog PurR - Staphylococcaceae
| Regulator type: | Transcription factor |
| Regulator family: | PurR |
| Regulation mode: | repressor |
| Biological process: | Purine metabolism |
| Effector: | 5-phosphoribosyl 1-pyrophosphate |
| Phylum: | Firmicutes |
| Visualization: | |
|
Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Staphylococcaceae
- By TF family - PurR
- By effector - 5-phosphoribosyl 1-pyrophosphate
- By pathway - Purine metabolism
| Genome | Genes | Operons |
|---|---|---|
| Staphylococcus aureus subsp. aureus N315 | 14 | 4 |
| Staphylococcus capitis SK14 | 13 | 3 |
| Staphylococcus epidermidis ATCC 12228 | 13 | 3 |
| Staphylococcus carnosus subsp. carnosus TM300 | 13 | 3 |
| Staphylococcus haemolyticus JCSC1435 | 14 | 4 |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | 14 | 4 |
| Macrococcus caseolyticus JCSC5402 | 14 | 4 |
| Genes | Function | |||||||
|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||
| purE |
*
Staphylococcus aureus subsp. aureus N315 Site: position = -136 score = 9.27833 sequence = AAAAGACGTAAATT-(18)-AAAGTTCGATTTTT Gene: SA0916: phosphoribosylaminoimidazole carboxylase catalytic subunit |
*
Staphylococcus capitis SK14 Site: position = -136 score = 9.27833 sequence = AAAAGACGTAAATT-(18)-AAAGTTCGATTTTT Gene: STACA0001_2300: phosphoribosylaminoimidazole carboxylase catalytic subunit |
*
Staphylococcus epidermidis ATCC 12228 Site: position = -137 score = 9.27833 sequence = AAAAGACGTAAATT-(18)-AAAGTTCGATTTTT Gene: SE0762: phosphoribosylaminoimidazole carboxylase catalytic subunit |
*
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -143 score = 9.28832 sequence = TAATTACGTAATTT-(18)-AAAGTTCGATTTTT Gene: Sca_0686: phosphoribosylaminoimidazole carboxylase catalytic subunit |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -136 score = 9.27833 sequence = AAAAGACGTAAATT-(18)-AAAGTTCGATTTTT Gene: SH1893: phosphoribosylaminoimidazole carboxylase catalytic subunit |
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -136 score = 8.9688 sequence = AAAAGACGTAGATT-(18)-AAAGTTCGATTTTT Gene: SSP1726: phosphoribosylaminoimidazole carboxylase catalytic subunit |
*
Macrococcus caseolyticus JCSC5402 Site: position = -193 score = 7.35057 sequence = AAAATACGAACGAA-(18)-AAAATACGTAATTG Gene: MCCL_0687: phosphoribosylaminoimidazole carboxylase catalytic subunit |
phosphoribosylaminoimidazole carboxylase catalytic subunit |
| purK |
Gene: SA0917: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
Gene: STACA0001_2299: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
Gene: SE0763: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
Gene: Sca_0687: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
Gene: SH1892: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
Gene: SSP1725: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
Gene: MCCL_0688: phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
phosphoribosylaminoimidazole carboxylase (EC:4.1.1.21) |
| purC |
Gene: SA0918: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
Gene: STACA0001_2298: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
Gene: SE0764: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
Gene: Sca_0688: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
Gene: SH1891: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
Gene: SSP1724: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
Gene: MCCL_0689: phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
phosphoribosylaminoimidazole-succinocarboxamide synthase (EC:6.3.2.6) |
| purS |
Gene: SA0919: phosphoribosylformylglycinamidine synthase, PurS protein |
Gene: STACA0001_2297: phosphoribosylformylglycinamidine synthase, PurS protein |
Gene: SE0765: phosphoribosylformylglycinamidine synthase, PurS protein |
Gene: Sca_0689: phosphoribosylformylglycinamidine synthase, PurS protein |
Gene: SH1890: phosphoribosylformylglycinamidine synthase, PurS protein |
Gene: SSP1723: phosphoribosylformylglycinamidine synthase, PurS protein |
Gene: MCCL_0690: phosphoribosylformylglycinamidine synthase, PurS protein |
phosphoribosylformylglycinamidine synthase, PurS protein |
| purQ |
Gene: SA0920: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
Gene: STACA0001_2296: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
Gene: SE0766: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
Gene: Sca_0690: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
Gene: SH1889: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
Gene: SSP1722: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
Gene: MCCL_0691: phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
phosphoribosylformylglycinamidine synthase I (EC:6.3.5.3) |
| purL |
Gene: SA0921: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
Gene: STACA0001_2295: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
Gene: SE0767: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
Gene: Sca_0691: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
Gene: SH1888: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
Gene: SSP1721: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
Gene: MCCL_0692: phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
phosphoribosylformylglycinamidine synthase II (EC:6.3.5.3) |
| purF |
Gene: SA0922: amidophosphoribosyltransferase (EC:2.4.2.14) |
Gene: STACA0001_2294: amidophosphoribosyltransferase (EC:2.4.2.14) |
Gene: SE0768: amidophosphoribosyltransferase (EC:2.4.2.14) |
Gene: Sca_0692: amidophosphoribosyltransferase (EC:2.4.2.14) |
Gene: SH1887: amidophosphoribosyltransferase (EC:2.4.2.14) |
Gene: SSP1720: amidophosphoribosyltransferase (EC:2.4.2.14) |
Gene: MCCL_0693: amidophosphoribosyltransferase (EC:2.4.2.14) |
amidophosphoribosyltransferase (EC:2.4.2.14) |
| purM |
Gene: SA0923: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
Gene: STACA0001_2293: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
Gene: SE0769: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
Gene: Sca_0693: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
Gene: SH1886: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
Gene: SSP1719: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
Gene: MCCL_0694: phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1) |
| purN |
Gene: SA0924: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
Gene: STACA0001_2292: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
Gene: SE0770: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
Gene: Sca_0694: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
Gene: SH1885: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
Gene: SSP1718: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
Gene: MCCL_0695: phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
phosphoribosylglycinamide formyltransferase (EC:2.1.2.2) |
| purH |
Gene: SA0925: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
Gene: STACA0001_2291: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
Gene: SE0771: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
Gene: Sca_0695: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
Gene: SH1884: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
Gene: SSP1717: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
Gene: MCCL_0696: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
phosphoribosylaminoimidazolecarboxamide formyltransferase (EC:2.1.2.3), IMP cyclohydrolase (EC:3.5.4.10) |
| purD |
Gene: SA0926: phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
Gene: STACA0001_2290: phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
Gene: SE0772: phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
Gene: Sca_0696: phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
Gene: SH1883: phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
Gene: SSP1716: phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
Gene: MCCL_0697: phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
phosphoribosylamine--glycine ligase (EC:6.3.4.13) |
| CRON 2. | ||||||||
| purB |
*
Staphylococcus aureus subsp. aureus N315 Site: position = -82 score = 8.39827 sequence = TAAAAACGAACTTT-(18)-AATGTTCTGTTTTT Gene: SA1724: adenylosuccinate lyase (EC:4.3.2.2) |
*
Staphylococcus capitis SK14 Site: position = -85 score = 8.75799 sequence = TAAATACGAACTTT-(18)-AATGTACAGTTTTT Gene: STACA0001_1961: adenylosuccinate lyase (EC:4.3.2.2) |
*
Staphylococcus epidermidis ATCC 12228 Site: position = -84 score = 7.86933 sequence = TAGAAACGAACTTT-(18)-AATGTACAGTTTTT Gene: SE1593: adenylosuccinate lyase (EC:4.3.2.2) |
Gene: Sca_1482: adenylosuccinate lyase (EC:4.3.2.2) |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -81 score = 8.00828 sequence = TAAAAACGAACTTT-(18)-AATGTACAGTTTTG Gene: SH1043: adenylosuccinate lyase (EC:4.3.2.2) |
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -89 score = 8.23857 sequence = TAAACACGAACTTT-(18)-AATGTACATGTTTT Gene: SSP0882: adenylosuccinate lyase (EC:4.3.2.2) |
*
Macrococcus caseolyticus JCSC5402 Site: position = -97 score = 9.04824 sequence = AATACACGAACTTT-(18)-AATGTACGGAATTT Gene: MCCL_1646: adenylosuccinate lyase (EC:4.3.2.2) |
adenylosuccinate lyase (EC:4.3.2.2) |
| CRON 3. | ||||||||
| purA |
*
Staphylococcus aureus subsp. aureus N315 Site: position = -114 score = 7.83032 sequence = AATGATTTTTCTTT-(17)-AATGTTCGATTTTT Gene: SA0016: adenylosuccinate synthase (EC:6.3.4.4) |
Gene: STACA0001_1358: adenylosuccinate synthase (EC:6.3.4.4) |
Gene: SE0016: adenylosuccinate synthase (EC:6.3.4.4) |
*
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -272 score = 6.74087 sequence = TTTTTACGTACAAT-(18)-ATTGTACGGTTTTT Gene: Sca_2459: adenylosuccinate synthase (EC:6.3.4.4) |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -272 score = 6.8006 sequence = TTTTACCGTATATT-(18)-AATGTGCGGTTTTT Gene: SH0016: adenylosuccinate synthase (EC:6.3.4.4) |
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -115 score = 7.28115 sequence = CACCATCAAAATTT-(18)-AATGTTCGATTTTT Site: position = -272 score = 7.17023 sequence = AATTTCCGTACAAT-(18)-ATTGTACGGTTTTT Gene: SSP0017: adenylosuccinate synthase (EC:6.3.4.4) |
*
Macrococcus caseolyticus JCSC5402 Site: position = -299 score = 8.04891 sequence = AAAAACCGTACATT-(18)-ATTGTACGGTTTTT Gene: MCCL_0019: adenylosuccinate synthase (EC:6.3.4.4) |
adenylosuccinate synthase (EC:6.3.4.4) |
| CRON 4. | ||||||||
| folD |
*
Staphylococcus aureus subsp. aureus N315 Site: position = -110 score = 9.24787 sequence = AAAAATCGAACTTT-(18)-AATTTACGTCTTTT Gene: SA0915: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
*
Staphylococcus capitis SK14 Site: position = -113 score = 9.24787 sequence = AAAAATCGAACTTT-(18)-AATTTACGTCTTTT Gene: STACA0001_2301: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
*
Staphylococcus epidermidis ATCC 12228 Site: position = -113 score = 9.24787 sequence = AAAAATCGAACTTT-(18)-AATTTACGTCTTTT Gene: SE0761: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
*
Staphylococcus carnosus subsp. carnosus TM300 Site: position = -117 score = 8.97787 sequence = AAAAATCGAACTTT-(18)-AAATTACGTAATTA Gene: Sca_0685: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
*
Staphylococcus haemolyticus JCSC1435 Site: position = -121 score = 9.24787 sequence = AAAAATCGAACTTT-(18)-AATTTACGTCTTTT Gene: SH1894: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -114 score = 8.98787 sequence = AAAAATCGAACTTT-(18)-AATCTACGTCTTTT Gene: SSP1727: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
*
Macrococcus caseolyticus JCSC5402 Site: position = -101 score = 7.35057 sequence = CAATTACGTATTTT-(18)-TTCGTTCGTATTTT Gene: MCCL_0686: methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
methylenetetrahydrofolate dehydrogenase (EC:1.5.1.5), methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |