Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CodY in Staphylococcus haemolyticus JCSC1435

Properties
Regulator type: Transcription factor
TF locus tag: SH1659
Regulator family: CodY
Regulation mode: repressor
Biological process: Amino acid metabolism
Effector: Branched-chain amino acids
Regulog: CodY - Staphylococcaceae
Statistics of regulated genes:
- Genes 122
- Operons 59
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 516 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -172
Score: 5
Sequence: AAAATTCAGAAAATT
Locus tag: SH2248
Name: SA0601
Funciton: hypothetical protein
SA0601
hypothetical protein

Position: -144
Score: 4.8
Sequence: AAATATCTGAAAATT
Locus tag: SH2590
Name: SA0367
Funciton: putative NADPH-flavin oxidoreductase
SA0367
putative NADPH-flavin oxidoreductase

Position: -279
Score: 4.9
Sequence: ACTTTTCTGAAAATT
Locus tag: SH2634
Name: SA0348
Funciton: putative transcriptional regulator
SA0348
putative transcriptional regulator

Position: -114
Score: 5.1
Sequence: AAATTTCAGAAAATT
Position: -105
Score: 4.4
Sequence: AAAATTTAAAATTTT
Locus tag: SH1574
Name: rocC
Funciton: amino acid permease
rocC
amino acid permease

Position: -41
Score: 4.5
Sequence: ATTAGTTAGAATATT
Position: -32
Score: 4
Sequence: AATATTCAAACTTTA
Locus tag: SH1838
Name: pycA
Funciton: pyruvate carboxylase
pycA
pyruvate carboxylase

Position: -65
Score: 4.9
Sequence: ATTATTCTAAAAATT
Locus tag: SH1916
Name: patA
Funciton: putative aminotransferase A
patA
putative aminotransferase A

Position: -134
Score: 4.1
Sequence: ATTAATTAAAATTTT
Locus tag: SH0606
Name: opuCA
Funciton: glycine betaine/carnitine/choline ABC transporter opuCA
Locus tag: SH0607
Name: opuCB
Funciton: glycine betaine/carnitine/choline ABC transporter opuCB
Locus tag: SH0608
Name: opuCC
Funciton: glycine betaine/carnitine/choline ABC transporter opuCC
Locus tag: SH0609
Name: opuCD
Funciton: glycine betaine/carnitine/choline ABC transporter opuCD
opuCA
glycine betaine/carnitine/choline ABC transporter opuCA
opuCB
glycine betaine/carnitine/choline ABC transporter opuCB
opuCC
glycine betaine/carnitine/choline ABC transporter opuCC
opuCD
glycine betaine/carnitine/choline ABC transporter opuCD

Position: -116
Score: 4.7
Sequence: AATTTTGTGAAAATT
Position: -60
Score: 4.9
Sequence: ATATTTCTGAAAATT
Locus tag: SH1970
Name: oppB
Funciton: oligopeptide ABC transporter permease protein OppB
Locus tag: SH1969
Name: oppC
Funciton: oligopeptide ABC transporter permease protein OppC
Locus tag: SH1968
Name: oppD
Funciton: oligopeptide ABC transporter ATP-binding protein OppD
Locus tag: SH1967
Name: oppF
Funciton: oligopeptide ABC transporter ATP-binding protein OppF
Locus tag: SH1966
Name: oppA
Funciton: oligopeptide ABC transporter OppA oligopeptide-binding protein
oppB
oligopeptide ABC transporter permease protein OppB
oppC
oligopeptide ABC transporter permease protein OppC
oppD
oligopeptide ABC transporter ATP-binding protein OppD
oppF
oligopeptide ABC transporter ATP-binding protein OppF
oppA
oligopeptide ABC transporter OppA oligopeptide-binding protein

Position: -253
Score: 4.5
Sequence: ATAAATCTGAAAATT
Position: -244
Score: 4.4
Sequence: AAAATTATAAATATT
Locus tag: SH0492
Name: mtnE
Funciton: transaminase MtnE involved in methionine biosynthesis via salvage pathway
Locus tag: SH0493
Name: ddh2
Funciton: D-lactate dehydrogenase
mtnE
transaminase MtnE involved in methionine biosynthesis via salvage pathway
ddh2
D-lactate dehydrogenase

Position: -189
Score: 5
Sequence: AATTTTCATAAAATT
Locus tag: SH0729
Name: metT
Funciton: methionine transporter MetT
metT
methionine transporter MetT

Position: -261
Score: 4.1
Sequence: AAAAGTTAAAATAAT
Locus tag: SH2047
Name: metN
Funciton: Methionine ABC transporter, ATP-binding protein
Locus tag: SH2046
Name: metP
Funciton: Methionine ABC transporter, permease protein
Locus tag: SH2045
Name: metQ
Funciton: Methionine ABC transporter, methionine-binding lipoprotein
metN
Methionine ABC transporter, ATP-binding protein
metP
Methionine ABC transporter, permease protein
metQ
Methionine ABC transporter, methionine-binding lipoprotein

Position: -550
Score: 4.9
Sequence: AATTTTCAGAAAAGT
Locus tag: SH2635
Name: metI
Funciton: cystathionine gamma-synthase
Locus tag: SH2636
Name: metC
Funciton: cystathionine beta-lyase
Locus tag: SH2637
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase protein
Locus tag: SH2638
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase
Locus tag: SH2639
Name: mdh
Funciton: hypothetical metal-dependent hydrolase
metI
cystathionine gamma-synthase
metC
cystathionine beta-lyase
metF
5,10-methylenetetrahydrofolate reductase protein
metE
5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase
mdh
hypothetical metal-dependent hydrolase

Position: -60
Score: 4.4
Sequence: TATATTCTAAATTTT
Position: -51
Score: 4.3
Sequence: AATTTTCAGATTTTA
Locus tag: SH2058
Name: lysE
Funciton: lysine exporter protein
lysE
lysine exporter protein

Position: -161
Score: 4.4
Sequence: AGTATTTAGAATTTT
Locus tag: SH1513
Name: ykuR
Funciton: hippurate hydrolase
Locus tag: SH1512
Name: dapX
Funciton: alanine racemase 2
Locus tag: SH1511
Name: lysA
Funciton: diaminopimelate decarboxylase
ykuR
hippurate hydrolase
dapX
alanine racemase 2
lysA
diaminopimelate decarboxylase

Position: -42
Score: 4.8
Sequence: AATTTTTTTAAAATT
Position: -33
Score: 4.3
Sequence: AAAATTCAAACAAAT
Locus tag: SH1517
Name: asd
Funciton: aspartate semialdehyde dehydrogenase
Locus tag: SH1516
Name: dapA
Funciton: Dihydrodipicolinate synthase
Locus tag: SH1515
Name: dapB
Funciton: dihydrodipicolinate reductase
Locus tag: SH1514
Name: dapD
Funciton: tetrahydrodipicolinate acetyltransferase
asd
aspartate semialdehyde dehydrogenase
dapA
Dihydrodipicolinate synthase
dapB
dihydrodipicolinate reductase
dapD
tetrahydrodipicolinate acetyltransferase

Position: -344
Score: 4.1
Sequence: ATTTTTCAGTCTATT
Locus tag: SH1518
Name: lysC
Funciton: aspartokinase II
lysC
aspartokinase II

Position: -104
Score: 4.5
Sequence: TATATTTAAAATATT
Position: -42
Score: 5.1
Sequence: AATTTTCAGAATAAT
Position: -33
Score: 4.3
Sequence: AATAATTAAATTATT
Locus tag: SH1592
Name: ltaE
Funciton: low specificity L-threonine aldolase
ltaE
low specificity L-threonine aldolase

Position: -123
Score: 4.4
Sequence: AAAATTTTAAATTTT
Position: -114
Score: 5.1
Sequence: AATTTTCTGAAATTT
Locus tag: SH1573
Name: katA
Funciton: catalase
katA
catalase

Position: -91
Score: 5.2
Sequence: AATTTTTAGAAAATT
Locus tag: SH2449
Name: ilvE
Funciton: branched-chain amino acid aminotroansferase
ilvE
branched-chain amino acid aminotroansferase

Position: -54
Score: 4.9
Sequence: AATTTTAAGAATATT
Position: -45
Score: 5.1
Sequence: AATATTCTAAATATT
Locus tag: SH0977
Name: ilvC
Funciton: alpha-keto-beta-hydroxylacil reductoisomerase
Locus tag: SH0976
Name: leuA
Funciton: 2-isopropylmalate synthase
Locus tag: SH0975
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase
Locus tag: SH0974
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit
Locus tag: SH0973
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit
Locus tag: SH0972
Name: ilvA
Funciton: thereonine dehydratase
ilvC
alpha-keto-beta-hydroxylacil reductoisomerase
leuA
2-isopropylmalate synthase
leuB
3-isopropylmalate dehydrogenase
leuC
3-isopropylmalate dehydratase large subunit
leuD
3-isopropylmalate dehydratase small subunit
ilvA
thereonine dehydratase

Position: -321
Score: 4.4
Sequence: AGTTGTTAGAAAATT
Locus tag: SH0980
Name: ilvD
Funciton: dihydroxy-acid dehydratase
Locus tag: SH0979
Name: ilvB
Funciton: acetolactate synthase large subunit
Locus tag: SH0978
Name: ilvH
Funciton: acetolactate synthase small subunit
ilvD
dihydroxy-acid dehydratase
ilvB
acetolactate synthase large subunit
ilvH
acetolactate synthase small subunit

Position: -178
Score: 4.7
Sequence: AAAAATCAGAAAATT
Locus tag: SH1579
Name: hom
Funciton: homoserine dehydrogenase
Locus tag: SH1578
Name: thrC
Funciton: threonine synthase
Locus tag: SH1577
Name: thrB
Funciton: homoserine kinase
Locus tag: SH1576
Name: SA1167
Funciton: putative hydrolase of the HAD superfamily
hom
homoserine dehydrogenase
thrC
threonine synthase
thrB
homoserine kinase
SA1167
putative hydrolase of the HAD superfamily

Position: -179
Score: 4.7
Sequence: AATTTTCAAAATTAT
Position: -52
Score: 4.5
Sequence: AATATCCAAAATATT
Locus tag: SH0902
Name: hmrA
Funciton: N-acyl-L-amino acid amidohydrolase
Locus tag: SH0903
Name: SA1934
Funciton: hypothetical protein
hmrA
N-acyl-L-amino acid amidohydrolase
SA1934
hypothetical protein

Position: -138
Score: 5.4
Sequence: AATTTTCAGAAAATT
Locus tag: SH2541
Name: gltC
Funciton: transcription activator of glutamate synthase operon
gltC
transcription activator of glutamate synthase operon

Position: -34
Score: 5.4
Sequence: AATTTTCTGAAAATT
Locus tag: SH2540
Name: gltB
Funciton: glutamate synthase large subunit
Locus tag: SH2539
Name: gltD
Funciton: NADPH-dependent glutamate synthase beta subunit
gltB
glutamate synthase large subunit
gltD
NADPH-dependent glutamate synthase beta subunit

Position: -145
Score: 4.6
Sequence: ATTATTCAGAAAATA
Locus tag: SH0459
Name: gabT
Funciton: 4-aminobutyrate aminotransferase
gabT
4-aminobutyrate aminotransferase

Position: -69
Score: 4.7
Sequence: ATTATTCTGACAATT
Locus tag: SH0413
Name: cysH
Funciton: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase
cysH
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase

Position: -37
Score: 5
Sequence: AATTATCAGAATATT
Position: -28
Score: 4.2
Sequence: AATATTCTATTAATT
Locus tag: SH0593
Name: cysD
Funciton: O-acetylhomoserine sulfhydrylase
cysD
O-acetylhomoserine sulfhydrylase

Position: -148
Score: 4.6
Sequence: AATATTCTGACTTTT
Locus tag: SH1926
Name: comK
Funciton: competence transcription factor
comK
competence transcription factor

Position: -367
Score: 4.6
Sequence: TATATTTAAAAAATT
Locus tag: SH0388
Name: capA
Funciton: capsular polysaccharide synthesis enzyme Cap5A
Locus tag: SH0389
Name: capB
Funciton: capsular polysaccharide synthesis enzyme Cap5B
Locus tag: SH0390
Name: capC
Funciton: capsular polysaccharide synthesis enzyme Cap8C
Locus tag: SH0391
Name: capD
Funciton: capsular polysaccharide synthesis enzyme Cap5D
Locus tag: SH0392
Name: capE
Funciton: capsular polysaccharide synthesis enzyme Cap8E
Locus tag: SH0393
Name: capF
Funciton: capsular polysaccharide synthesis enzyme Cap5F
Locus tag: SH0394
Name: capG
Funciton: capsular polysaccharide synthesis enzyme Cap5G
Locus tag: SH0395
Name: capH
Funciton: hypothetical protein
Locus tag: SH0396
Name: capI
Funciton: hypothetical protein
Locus tag: SH0397
Name: capJ
Funciton: hypothetical protein
Locus tag: SH0398
Name: capK
Funciton: hypothetical protein
Locus tag: SH0399
Name: capL
Funciton: hypothetical protein
capA
capsular polysaccharide synthesis enzyme Cap5A
capB
capsular polysaccharide synthesis enzyme Cap5B
capC
capsular polysaccharide synthesis enzyme Cap8C
capD
capsular polysaccharide synthesis enzyme Cap5D
capE
capsular polysaccharide synthesis enzyme Cap8E
capF
capsular polysaccharide synthesis enzyme Cap5F
capG
capsular polysaccharide synthesis enzyme Cap5G
capH
hypothetical protein
capI
hypothetical protein
capJ
hypothetical protein
capK
hypothetical protein
capL
hypothetical protein

Position: -81
Score: 4.5
Sequence: AATTTATTGAATATT
Locus tag: SH0145
Name: brnQ1
Funciton: branched-chain amino acid transport system
brnQ1
branched-chain amino acid transport system

Position: -87
Score: 4.2
Sequence: AATTTTCTGAAATCA
Locus tag: SH1502
Name: braB
Funciton: branched-chain amino acid transport system
braB
branched-chain amino acid transport system

Position: -72
Score: 4
Sequence: CTTTTTTAAAATTTT
Locus tag: SH1104
Name: artQ
Funciton: Arginine ABC transport system ArtQ
Locus tag: SH1105
Name: artM
Funciton: Arginine ABC transport system ATP-binding protein ArtM
artQ
Arginine ABC transport system ArtQ
artM
Arginine ABC transport system ATP-binding protein ArtM

Position: -124
Score: 4.7
Sequence: AATTATTAAAATATT
Position: -115
Score: 4.6
Sequence: AATATTCTAATAAAT
Locus tag: SH1446
Name: aroC
Funciton: chorismate synthase
Locus tag: SH1447
Name: aroB
Funciton: 3-dehydroquinate synthase
Locus tag: SH1448
Name: aroA
Funciton: 3-phosphoshikimate 1-carboxyvinyltransferase
Locus tag: SH1449
Name: SA1296
Funciton: hypothetical protein
Locus tag: SH1450
Name: SA1295
Funciton: hypothetical protein
Locus tag: SH1451
Name: SA1294
Funciton: hypothetical protein
Locus tag: SH1452
Name: SA1293
Funciton: hypothetical protein
aroC
chorismate synthase
aroB
3-dehydroquinate synthase
aroA
3-phosphoshikimate 1-carboxyvinyltransferase
SA1296
hypothetical protein
SA1295
hypothetical protein
SA1294
hypothetical protein
SA1293
hypothetical protein

Position: -31
Score: 5.1
Sequence: AATTTTCAGAAAAAT
Locus tag: SH1989
Name: argG
Funciton: argininosuccinate synthase
Locus tag: SH1990
Name: argH
Funciton: argininosuccinate lyase
argG
argininosuccinate synthase
argH
argininosuccinate lyase

Position: -124
Score: 4.1
Sequence: ATATGTTAAAATATT
Locus tag: SH0996
Name: agrB
Funciton: accessory gene regulator B
Locus tag: SH0995
Name: agrD
Funciton: accessory gene regulator D
Locus tag: SH0994
Name: agrC
Funciton: accessory gene regulator C
Locus tag: SH0993
Name: agrA
Funciton: accessory gene regulator A
agrB
accessory gene regulator B
agrD
accessory gene regulator D
agrC
accessory gene regulator C
agrA
accessory gene regulator A

Position: -92
Score: 4.9
Sequence: AATTTTTAGATAATT
Locus tag: SH1188
Name: acuA
Funciton: acetoin dehydrogenase
Locus tag: SH1187
Name: acuC
Funciton: acetoin utilization protein
acuA
acetoin dehydrogenase
acuC
acetoin utilization protein

Position: -87
Score: 4.9
Sequence: AATTATCTAAAAATT
Locus tag: SH1189
Name: acsA
Funciton: acetyl-CoA synthetase
acsA
acetyl-CoA synthetase

Position: -231
Score: 5.1
Sequence: AATTTTCAGAAATTT
Locus tag: SH0623
Name: aapA
Funciton: D-serine/D-alanine/glycine transporter
aapA
D-serine/D-alanine/glycine transporter

Position: -45
Score: 4.6
Sequence: TATTATCTGAAAATT
Position: -36
Score: 4.1
Sequence: AAAATTCTAAATAAA
Locus tag: SH2223
Name: yxjH
Funciton: putative methionine synthase II
yxjH
putative methionine synthase II

Position: -35
Score: 4.8
Sequence: CATATTCTGAAAATT
Locus tag: SH1544
Name: tyrA
Funciton: prephenate dehydrogenase
tyrA
prephenate dehydrogenase

Position: -453
Score: 4.3
Sequence: AAATATCAAACAATT
Locus tag: SH1542
Name: trpE
Funciton: anthranilate synthase component I
Locus tag: SH1541
Name: trpG
Funciton: anthranilate synthase component II
Locus tag: SH1540
Name: trpD
Funciton: anthranilate phosphoribosyltransferase
Locus tag: SH1539
Name: trpC
Funciton: indole-3-glycerol phosphate synthase
Locus tag: SH1538
Name: trpF
Funciton: phosphoriborylanthranilate isomerase
Locus tag: SH1537
Name: trpB
Funciton: tryptophan synthase beta subunit
Locus tag: SH1536
Name: trpA
Funciton: tryptophan synthase alpha subunit
trpE
anthranilate synthase component I
trpG
anthranilate synthase component II
trpD
anthranilate phosphoribosyltransferase
trpC
indole-3-glycerol phosphate synthase
trpF
phosphoriborylanthranilate isomerase
trpB
tryptophan synthase beta subunit
trpA
tryptophan synthase alpha subunit

Position: -102
Score: 5
Sequence: AAATTTCTAAAAATT
Locus tag: SH2166
Name: tppB
Funciton: di-tripepride ABC transporter
tppB
di-tripepride ABC transporter

Position: -35
Score: 4.7
Sequence: AATTTTCTGATTTTT
Locus tag: SH1580
Name: thrA
Funciton: aspartokinase III
thrA
aspartokinase III

Position: -248
Score: 4.3
Sequence: AATTATTTAAAAATA
Locus tag: SH1363
Name: sodA
Funciton: superoxide dismutase SodA
sodA
superoxide dismutase SodA

Position: -28
Score: 4.8
Sequence: AATTTTCAGATATTT
Locus tag: SH2591
Name: SE2356
Funciton: hypothetical protein
SE2356
hypothetical protein

Position: -194
Score: 4.3
Sequence: AATAATTTAATTATT
Position: -185
Score: 5.1
Sequence: ATTATTCTGAAAATT
Position: -123
Score: 4.5
Sequence: AATATTTTAAATATA
Locus tag: SH1591
Name: SAS040
Funciton: hypothetical protein
Locus tag: SH1590
Name: SA1155
Funciton: putative cardiolipin synthetase
SAS040
hypothetical protein
SA1155
putative cardiolipin synthetase

Position: -248
Score: 4.5
Sequence: AATTTTTTAACATTT
Locus tag: SH2406
Name: SE0357
Funciton: hypothetical protein
Locus tag: SH2407
Name: SE0356
Funciton: hypothetical protein
SE0357
hypothetical protein
SE0356
hypothetical protein

Position: -89
Score: 5
Sequence: AATTTTTAAAATATT
Position: -80
Score: 4.8
Sequence: AATATTCTAAATTTT
Locus tag: SH0457
Name: SA2398
Funciton: hypothetical protein
SA2398
hypothetical protein

Position: -114
Score: 5.1
Sequence: AATTTTCAGAAATTT
Locus tag: SH0460
Name: SA2396
Funciton: putative amino acid transporter
SA2396
putative amino acid transporter

Position: -156
Score: 5.3
Sequence: AATATTCTGAAAATT
Position: -147
Score: 4.1
Sequence: AAAATTTAGAATTTG
Locus tag: SH0484
Name: SA2357
Funciton: putative regulatory protein
SA2357
putative regulatory protein

Position: -75
Score: 5.1
Sequence: AAATTTCTGAAAATT
Locus tag: SH0589
Name: SA2261
Funciton: putative p-aminobenzoyl-glutamate transporter
SA2261
putative p-aminobenzoyl-glutamate transporter

Position: -209
Score: 5.1
Sequence: AATTTTCAGAAATTT
Locus tag: SH0590
Name: SA2260
Funciton: putative short chain dehydrogenase
SA2260
putative short chain dehydrogenase

Position: -76
Score: 4.8
Sequence: AATTTTTAAAAATTT
Position: -51
Score: 4.2
Sequence: AAATTTTTAAATTAT
Locus tag: SH0156
Name: SA2002
Funciton: hypothetical regulator
SA2002
hypothetical regulator

Position: -55
Score: 5
Sequence: AATTATCAGAATATT
Locus tag: SH1201
Name: SA1544
Funciton: putative phosphoserine transaminase
Locus tag: SH1200
Name: serA
Funciton: D-3-phosphoglycerate dehydrogenase
SA1544
putative phosphoserine transaminase
serA
D-3-phosphoglycerate dehydrogenase

Position: -66
Score: 4.3
Sequence: AAAATTTTGATAAAT
Locus tag: SH1382
Name: SA1364
Funciton: putative sulfurtransferase
SA1364
putative sulfurtransferase

Position: -100
Score: 4.3
Sequence: ATTTATCAAAATTTT
Locus tag: SH1383
Name: SA1363
Funciton: Lipoate-protein ligase A
SA1363
Lipoate-protein ligase A

Position: -80
Score: 4.6
Sequence: AAAAGTCAGAATATT
Locus tag: SH1925
Name: SA0883
Funciton: hypothetical protein
SA0883
hypothetical protein

Position: -200
Score: 4.1
Sequence: TTTATTTAGAATTTT
Position: -191
Score: 4.6
Sequence: AATTTTCAGATAATA
Locus tag: SH2222
Name: SA0626
Funciton: hypothetical protein
SA0626
hypothetical protein
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