Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CodY in Staphylococcus carnosus subsp. carnosus TM300

Properties
Regulator type: Transcription factor
TF locus tag: Sca_0890
Regulator family: CodY
Regulation mode: repressor
Biological process: Amino acid metabolism
Effector: Branched-chain amino acids
Regulog: CodY - Staphylococcaceae
Statistics of regulated genes:
- Genes 120
- Operons 51
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 516 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -34
Score: 4.6
Sequence: AAAATTCAAATAATT
Locus tag: Sca_0740
Name: pycA
Funciton: pyruvate carboxylase
pycA
pyruvate carboxylase

Position: -108
Score: 4.2
Sequence: TTTATTCTAAAATTT
Locus tag: Sca_0656
Name: patA
Funciton: putative aminotransferase A
patA
putative aminotransferase A

Position: -517
Score: 4.7
Sequence: ATTTGTCTGAATATT
Locus tag: Sca_1934
Name: opuCA
Funciton: glycine betaine/carnitine/choline ABC transporter opuCA
Locus tag: Sca_1933
Name: opuCB
Funciton: glycine betaine/carnitine/choline ABC transporter opuCB
Locus tag: Sca_1932
Name: opuCC
Funciton: glycine betaine/carnitine/choline ABC transporter opuCC
Locus tag: Sca_1931
Name: opuCD
Funciton: glycine betaine/carnitine/choline ABC transporter opuCD
Locus tag: Sca_1930
Name: SE0226
Funciton: putative esterase
opuCA
glycine betaine/carnitine/choline ABC transporter opuCA
opuCB
glycine betaine/carnitine/choline ABC transporter opuCB
opuCC
glycine betaine/carnitine/choline ABC transporter opuCC
opuCD
glycine betaine/carnitine/choline ABC transporter opuCD
SE0226
putative esterase

Position: -113
Score: 5.2
Sequence: AATATTCTAAAAATT
Position: -65
Score: 4.2
Sequence: AATATTAAAATATTT
Position: -56
Score: 4.9
Sequence: ATATTTCTGAAAATT
Locus tag: Sca_0588
Name: oppB
Funciton: oligopeptide ABC transporter permease protein OppB
Locus tag: Sca_0589
Name: oppC
Funciton: oligopeptide ABC transporter permease protein OppC
Locus tag: Sca_0590
Name: oppD
Funciton: oligopeptide ABC transporter ATP-binding protein OppD
Locus tag: Sca_0591
Name: oppF
Funciton: oligopeptide ABC transporter ATP-binding protein OppF
Locus tag: Sca_0592
Name: oppA
Funciton: oligopeptide ABC transporter OppA oligopeptide-binding protein
oppB
oligopeptide ABC transporter permease protein OppB
oppC
oligopeptide ABC transporter permease protein OppC
oppD
oligopeptide ABC transporter ATP-binding protein OppD
oppF
oligopeptide ABC transporter ATP-binding protein OppF
oppA
oligopeptide ABC transporter OppA oligopeptide-binding protein

Position: -257
Score: 4.4
Sequence: AAATGTCAGAATTTT
Locus tag: Sca_0010
Name: mtnE
Funciton: transaminase MtnE involved in methionine biosynthesis via salvage pathway
mtnE
transaminase MtnE involved in methionine biosynthesis via salvage pathway

Position: -116
Score: 4.7
Sequence: AATTATCTGAATTTT
Position: -57
Score: 4.2
Sequence: TTTATTCAAAAAAAT
Locus tag: Sca_1975
Name: ddh2
Funciton: D-lactate dehydrogenase
ddh2
D-lactate dehydrogenase

Position: -282
Score: 4.7
Sequence: ATTTATTAGAAAATT
Position: -273
Score: 4.2
Sequence: AAAATTTAAAATAGT
Locus tag: Sca_0455
Name: metN
Funciton: Methionine ABC transporter, ATP-binding protein
Locus tag: Sca_0456
Name: metP
Funciton: Methionine ABC transporter, permease protein
Locus tag: Sca_0457
Name: metQ
Funciton: Methionine ABC transporter, methionine-binding lipoprotein
metN
Methionine ABC transporter, ATP-binding protein
metP
Methionine ABC transporter, permease protein
metQ
Methionine ABC transporter, methionine-binding lipoprotein

Position: -574
Score: 5.1
Sequence: ATTATTCTGAAAATT
Locus tag: Sca_0014
Name: metC
Funciton: cystathionine gamma-synthase
Locus tag: Sca_0013
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase protein
Locus tag: Sca_0012
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase
Locus tag: Sca_0011
Name: mdh
Funciton: hypothetical metal-dependent hydrolase
metC
cystathionine gamma-synthase
metF
5,10-methylenetetrahydrofolate reductase protein
metE
5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase
mdh
hypothetical metal-dependent hydrolase

Position: -340
Score: 4.3
Sequence: AAATTTCTAAAAATC
Locus tag: Sca_1037
Name: lysC
Funciton: aspartokinase II
Locus tag: Sca_1038
Name: asd
Funciton: aspartate semialdehyde dehydrogenase
Locus tag: Sca_1039
Name: dapA
Funciton: dihydrodipicolinate synthase
Locus tag: Sca_1040
Name: dapB
Funciton: dihydrodipicolinate reductase
Locus tag: Sca_1041
Name: dapD
Funciton: tetrahydrodipicolinate acetyltransferase
Locus tag: Sca_1042
Name: ykuR
Funciton: peptidase (peptidase family M20/M25/M40)
Locus tag: Sca_1043
Name: dapX
Funciton: alanine racemase
Locus tag: Sca_1044
Name: lysA
Funciton: diaminopimelate decarboxylase
lysC
aspartokinase II
asd
aspartate semialdehyde dehydrogenase
dapA
dihydrodipicolinate synthase
dapB
dihydrodipicolinate reductase
dapD
tetrahydrodipicolinate acetyltransferase
ykuR
peptidase (peptidase family M20/M25/M40)
dapX
alanine racemase
lysA
diaminopimelate decarboxylase

Position: -101
Score: 5.3
Sequence: AATTTTCTGAATATT
Locus tag: Sca_1514
Name: ltaE
Funciton: low specificity L-threonine aldolase
ltaE
low specificity L-threonine aldolase

Position: -28
Score: 4.1
Sequence: ATTATTCTAAATAAG
Locus tag: Sca_2336
Name: katA
Funciton: catalase
katA
catalase

Position: -101
Score: 4.5
Sequence: ATTTTTTTAAATTTT
Position: -92
Score: 4.8
Sequence: AATTTTCTAAAAACT
Locus tag: Sca_0215
Name: ilvE
Funciton: branched-chain amino acid aminotroansferase
ilvE
branched-chain amino acid aminotroansferase

Position: -52
Score: 4.8
Sequence: AAAATTCTAAATATT
Locus tag: Sca_1562
Name: ilvC
Funciton: alpha-keto-beta-hydroxylacil reductoisomerase
Locus tag: Sca_1563
Name: leuA
Funciton: 2-isopropylmalate synthase
Locus tag: Sca_1564
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase
Locus tag: Sca_1565
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit
Locus tag: Sca_1566
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit
Locus tag: Sca_1567
Name: ilvA
Funciton: thereonine dehydratase
ilvC
alpha-keto-beta-hydroxylacil reductoisomerase
leuA
2-isopropylmalate synthase
leuB
3-isopropylmalate dehydrogenase
leuC
3-isopropylmalate dehydratase large subunit
leuD
3-isopropylmalate dehydratase small subunit
ilvA
thereonine dehydratase

Position: -316
Score: 4.8
Sequence: AATTTTAAAAAAATT
Position: -307
Score: 4.3
Sequence: AAAATTCTAATAAAT
Locus tag: Sca_1559
Name: ilvD
Funciton: dihydroxy-acid dehydratase
Locus tag: Sca_1560
Name: ilvB
Funciton: acetolactate synthase large subunit
Locus tag: Sca_1561
Name: ilvH
Funciton: acetolactate synthase small subunit
ilvD
dihydroxy-acid dehydratase
ilvB
acetolactate synthase large subunit
ilvH
acetolactate synthase small subunit

Position: -127
Score: 4.2
Sequence: AAATTTCAACATATT
Position: -109
Score: 4.4
Sequence: AATTTTTTGAACTTT
Locus tag: Sca_0970
Name: hom
Funciton: homoserine dehydrogenase
Locus tag: Sca_0971
Name: thrC
Funciton: threonine synthase
Locus tag: Sca_0972
Name: thrB
Funciton: homoserine kinase
Locus tag: Sca_0973
Name: SA1167
Funciton: putative hydrolase of the HAD superfamily
hom
homoserine dehydrogenase
thrC
threonine synthase
thrB
homoserine kinase
SA1167
putative hydrolase of the HAD superfamily

Position: -176
Score: 4.1
Sequence: AATTTATTAAATTTT
Locus tag: Sca_1636
Name: hmrA/SA1934
Funciton: N-acyl-L-amino acid amidohydrolase / hypothetical protein
hmrA/SA1934
N-acyl-L-amino acid amidohydrolase / hypothetical protein

Position: -125
Score: 4.2
Sequence: ATTTTTATTAATATT
Position: -116
Score: 5
Sequence: AATATTCAGAATTTT
Locus tag: Sca_0637
Name: hisZ
Funciton: ATP phosphoribosyltransferase regulatory subunit
Locus tag: Sca_0636
Name: hisG
Funciton: ATP phosphoribosyltransferase
Locus tag: Sca_0635
Name: hisD
Funciton: histidinol dehydrogenase
Locus tag: Sca_0634
Name: hisC
Funciton: histidinol-phosphate aminotransferase
Locus tag: Sca_0633
Name: hisB
Funciton: imidazoleglycerol-phosphate dehydratase
Locus tag: Sca_0632
Name: hisH
Funciton: imidazole glycerol phosphate synthase glutamine amidotransferase subunit
Locus tag: Sca_0631
Name: hisA
Funciton: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Locus tag: Sca_0630
Name: hisF
Funciton: imidazoleglycerol-phosphate synthase
Locus tag: Sca_0629
Name: hisI
Funciton: putatve histidine biosynthesis bifunctional protein HisIE
hisZ
ATP phosphoribosyltransferase regulatory subunit
hisG
ATP phosphoribosyltransferase
hisD
histidinol dehydrogenase
hisC
histidinol-phosphate aminotransferase
hisB
imidazoleglycerol-phosphate dehydratase
hisH
imidazole glycerol phosphate synthase glutamine amidotransferase subunit
hisA
phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
hisF
imidazoleglycerol-phosphate synthase
hisI
putatve histidine biosynthesis bifunctional protein HisIE

Position: -113
Score: 4.7
Sequence: AATTTTCAGATTTTT
Position: -39
Score: 4.5
Sequence: ATTATTCTAATTATT
Locus tag: Sca_0104
Name: gltC
Funciton: transcription activator of glutamate synthase operon
gltC
transcription activator of glutamate synthase operon

Position: -117
Score: 4.5
Sequence: AATAATTAGAATAAT
Position: -43
Score: 4.7
Sequence: AAAAATCTGAAAATT
Locus tag: Sca_0105
Name: gltB
Funciton: glutamate synthase large subunit
Locus tag: Sca_0106
Name: gltD
Funciton: NADPH-dependent glutamate synthase beta subunit
gltB
glutamate synthase large subunit
gltD
NADPH-dependent glutamate synthase beta subunit

Position: -157
Score: 4.8
Sequence: AATTTACAGAAAATT
Locus tag: Sca_0958
Name: glnR
Funciton: HTH-type transcriptional regulator GlnR
Locus tag: Sca_0957
Name: glnA
Funciton: glutamine synthetase
glnR
HTH-type transcriptional regulator GlnR
glnA
glutamine synthetase

Position: -127
Score: 4.8
Sequence: AAATATCTGAAAATT
Locus tag: Sca_0283
Name: gabT
Funciton: 4-aminobutyrate aminotransferase
gabT
4-aminobutyrate aminotransferase

Position: -105
Score: 5
Sequence: AAATTTCTGAATATT
Locus tag: Sca_2142
Name: fmdA
Funciton: putative formamidase
fmdA
putative formamidase

Position: -80
Score: 4.6
Sequence: TATTTTCAGACAATT
Locus tag: Sca_0058
Name: cysH
Funciton: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase
cysH
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase

Position: -145
Score: 4.6
Sequence: AATATTCTGACTTTT
Position: -136
Score: 4.1
Sequence: ACTTTTTAAAAAATA
Locus tag: Sca_0642
Name: comK
Funciton: competence transcription factor
comK
competence transcription factor

Position: -118
Score: 4.1
Sequence: AATAATTAGAAATTG
Position: -81
Score: 4.3
Sequence: AAAAATTTGAAATTT
Locus tag: Sca_2357
Name: capA
Funciton: capsular polysaccharide synthesis enzyme Cap5A
Locus tag: Sca_2356
Name: capB
Funciton: capsular polysaccharide synthesis enzyme Cap5B
Locus tag: Sca_2355
Name: capC
Funciton: capsular polysaccharide synthesis enzyme Cap8C
Locus tag: Sca_2354
Name: capD
Funciton: capsular polysaccharide synthesis enzyme Cap5D
Locus tag: Sca_2353
Name: capD
Funciton: capsular polysaccharide synthesis enzyme Cap5D
Locus tag: Sca_2352
Name: null
Funciton: hypothetical protein
Locus tag: Sca_2351
Name: null
Funciton: hypothetical protein
Locus tag: Sca_2350
Name: null
Funciton: hypothetical protein
Locus tag: Sca_2349
Name: capI
Funciton: capsular polysaccharide synthesis enzyme Cap5I
Locus tag: Sca_2348
Name: capO
Funciton: capsular polysaccharide synthesis enzyme Cap8O
Locus tag: Sca_2347
Name: null
Funciton: hypothetical protein
Locus tag: Sca_2346
Name: null
Funciton: putative capsular polysaccharide biosynthesis protein
Locus tag: Sca_2345
Name: null
Funciton: hypothetical protein
Locus tag: Sca_2344
Name: capM
Funciton: capsular polysaccharide synthesis enzyme Cap5M
capA
capsular polysaccharide synthesis enzyme Cap5A
capB
capsular polysaccharide synthesis enzyme Cap5B
capC
capsular polysaccharide synthesis enzyme Cap8C
capD
capsular polysaccharide synthesis enzyme Cap5D
capD
capsular polysaccharide synthesis enzyme Cap5D
hypothetical protein
hypothetical protein
hypothetical protein
capI
capsular polysaccharide synthesis enzyme Cap5I
capO
capsular polysaccharide synthesis enzyme Cap8O
hypothetical protein
putative capsular polysaccharide biosynthesis protein
hypothetical protein
capM
capsular polysaccharide synthesis enzyme Cap5M

Position: -68
Score: 4.6
Sequence: ATTATTCAGAAAATA
Locus tag: Sca_0065
Name: butA
Funciton: acetoin reductase
butA
acetoin reductase

Position: -53
Score: 5
Sequence: AATATTCAGAAATTT
Locus tag: Sca_0418
Name: brnQ2
Funciton: branched-chain amino acid transport system
brnQ2
branched-chain amino acid transport system

Position: -96
Score: 4.7
Sequence: AATTTTCAGAAAGTT
Locus tag: Sca_1051
Name: braB
Funciton: branched-chain amino acid transport system
braB
branched-chain amino acid transport system

Position: -83
Score: 5.1
Sequence: AAATTTCAGAAAATT
Position: -74
Score: 4
Sequence: AAAATTTAAAAATTA
Locus tag: Sca_1432
Name: artQ
Funciton: Arginine ABC transport system ArtQ
Locus tag: Sca_1431
Name: artM
Funciton: Arginine ABC transport system ATP-binding protein ArtM
artQ
Arginine ABC transport system ArtQ
artM
Arginine ABC transport system ATP-binding protein ArtM

Position: -33
Score: 4.5
Sequence: AAAATTCTAACTATT
Locus tag: Sca_0569
Name: argG
Funciton: argininosuccinate synthase
Locus tag: Sca_0568
Name: argH
Funciton: argininosuccinate lyase
argG
argininosuccinate synthase
argH
argininosuccinate lyase

Position: -65
Score: 4.6
Sequence: AATAGTCAGACAATT
Locus tag: Sca_0936
Name: appA
Funciton: oligopeptide transport system oligopeptide-binding protein AppA
Locus tag: Sca_0937
Name: appD
Funciton: oligopeptide transport system ATP-binding protein AppD
Locus tag: Sca_0938
Name: appF
Funciton: oligopeptide transport system ATP-binding protein AppF
Locus tag: Sca_0939
Name: appB
Funciton: oligopeptide transport system permease protein AppB
Locus tag: Sca_0940
Name: appC
Funciton: oligopeptide transport system permease protein AppC
appA
oligopeptide transport system oligopeptide-binding protein AppA
appD
oligopeptide transport system ATP-binding protein AppD
appF
oligopeptide transport system ATP-binding protein AppF
appB
oligopeptide transport system permease protein AppB
appC
oligopeptide transport system permease protein AppC

Position: -159
Score: 4.1
Sequence: ATAATTATGATAATT
Position: -150
Score: 4.2
Sequence: ATAATTCTGATTTTT
Locus tag: Sca_1339
Name: acuA
Funciton: acetoin utilization protein
Locus tag: Sca_1340
Name: acuC
Funciton: putative acetoin utilization protein
acuA
acetoin utilization protein
acuC
putative acetoin utilization protein

Position: -96
Score: 4.2
Sequence: AAAAATCAGAATTAT
Position: -87
Score: 4.1
Sequence: AATTATCATAATTAT
Locus tag: Sca_1338
Name: acsA
Funciton: acetyl-CoA synthetase
acsA
acetyl-CoA synthetase

Position: -126
Score: 4.6
Sequence: AATTTTCTTATAATT
Locus tag: Sca_1918
Name: aapA
Funciton: D-serine/D-alanine/glycine transporter
aapA
D-serine/D-alanine/glycine transporter

Position: -464
Score: 4.3
Sequence: CATTATTAAAAAATT
Locus tag: Sca_1012
Name: trpE
Funciton: anthranilate synthase component I
Locus tag: Sca_1013
Name: trpG
Funciton: anthranilate synthase component II
Locus tag: Sca_1014
Name: trpD
Funciton: anthranilate phosphoribosyltransferase
Locus tag: Sca_1015
Name: trpC
Funciton: indole-3-glycerol phosphate synthase
Locus tag: Sca_1016
Name: trpF
Funciton: phosphoriborylanthranilate isomerase
Locus tag: Sca_1017
Name: trpB
Funciton: tryptophan synthase beta subunit
Locus tag: Sca_1018
Name: trpA
Funciton: tryptophan synthase alpha subunit
trpE
anthranilate synthase component I
trpG
anthranilate synthase component II
trpD
anthranilate phosphoribosyltransferase
trpC
indole-3-glycerol phosphate synthase
trpF
phosphoriborylanthranilate isomerase
trpB
tryptophan synthase beta subunit
trpA
tryptophan synthase alpha subunit

Position: -114
Score: 5.3
Sequence: AATATTCTGAAAATT
Position: -88
Score: 4.5
Sequence: TATTTTAAGAAAATT
Locus tag: Sca_0374
Name: tppB
Funciton: di-tripepride ABC transporter
tppB
di-tripepride ABC transporter

Position: -97
Score: 4.4
Sequence: AAAGTTCAAAAAATT
Position: -79
Score: 4.2
Sequence: AATATGTTGAAATTT
Locus tag: Sca_0969
Name: thrA
Funciton: aspartokinase III
thrA
aspartokinase III

Position: -34
Score: 4.3
Sequence: AATAATATAAATATT
Locus tag: Sca_0040
Name: SE2356
Funciton: putative 2-keto-4-pentenoate hydratase
SE2356
putative 2-keto-4-pentenoate hydratase

Position: -61
Score: 5
Sequence: AATTTTCAAAAAAAT
Locus tag: Sca_0240
Name: SE0357
Funciton: hypothetical protein
Locus tag: Sca_0239
Name: SE0356
Funciton: hypothetical protein
SE0357
hypothetical protein
SE0356
hypothetical protein

Position: -90
Score: 5.2
Sequence: AATATTTAGAAAATT
Position: -81
Score: 4.2
Sequence: AAAATTATAAAAAAT
Locus tag: Sca_1748
Name: Sca_1748
Funciton: hypothetical protein
Locus tag: Sca_1747
Name: Sca_1747
Funciton: hypothetical protein
Sca_1748
hypothetical protein
Sca_1747
hypothetical protein

Position: -139
Score: 5.2
Sequence: AATTTTCAAAATATT
Locus tag: Sca_1398
Name: Sca_1398
Funciton: hypothetical protein
Sca_1398
hypothetical protein

Position: -91
Score: 5.2
Sequence: AATATTCAGAATATT
Position: -82
Score: 4.5
Sequence: AATATTTAAAATATA
Locus tag: Sca_0238
Name: Sca_0238
Funciton: hypothetical protein
Sca_0238
hypothetical protein

Position: -282
Score: 4.7
Sequence: CATATTTTGAAAATT
Position: -69
Score: 4.5
Sequence: TATTATCAGAATATT
Locus tag: Sca_2043
Name: SA2357
Funciton: putative regulatory protein
SA2357
putative regulatory protein

Position: -83
Score: 4.8
Sequence: AATTTTCAGAATTAT
Locus tag: Sca_2265
Name: SA2261
Funciton: putative aminobenzoyl-glutamate transport protein
SA2261
putative aminobenzoyl-glutamate transport protein

Position: -468
Score: 4.4
Sequence: ATTATACTGAAAATT
Position: -414
Score: 4.4
Sequence: AATATTCAAATAATA
Locus tag: Sca_1812
Name: SA2109
Funciton: probable amino-acid or metabolite transporter
SA2109
probable amino-acid or metabolite transporter

Position: -55
Score: 4.9
Sequence: TATTTTCAGAATATT
Locus tag: Sca_1329
Name: SA1544
Funciton: putative phosphoserine transaminase
Locus tag: Sca_1330
Name: serA
Funciton: D-3-phosphoglycerate dehydrogenase
SA1544
putative phosphoserine transaminase
serA
D-3-phosphoglycerate dehydrogenase

Position: -178
Score: 4.2
Sequence: AATTATAAAAATAAT
Position: -91
Score: 4.1
Sequence: TATTTTTTAAAAAGT
Position: -82
Score: 4.6
Sequence: AAAAGTCAGAATATT
Locus tag: Sca_0643
Name: SA0883
Funciton: hypothetical protein
SA0883
hypothetical protein

Position: -120
Score: 4.8
Sequence: AATTTTCAGAATTAT
Locus tag: Sca_0294
Name: SA0601
Funciton: hypothetical protein
SA0601
hypothetical protein

Position: -140
Score: 4.3
Sequence: AATATTTATATTATT
Locus tag: Sca_0041
Name: SA0367
Funciton: putative NADPH-flavin oxidoreductase
SA0367
putative NADPH-flavin oxidoreductase

Position: -192
Score: 5.1
Sequence: AATTTTCAGAATAAT
Position: -115
Score: 4.9
Sequence: AATTTTTTGAATTTT
Locus tag: Sca_0015
Name: SA0348
Funciton: putative transcriptional regulator
SA0348
putative transcriptional regulator

Position: -121
Score: 4.3
Sequence: TTTTTTCAGAATTTT
Position: -112
Score: 4.7
Sequence: AATTTTTTAAATTTT
Locus tag: Sca_0975
Name: rocC
Funciton: amino acid permease
rocC
amino acid permease
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