Regulon of CodY in Staphylococcus epidermidis ATCC 12228

Properties
Regulator type:	Transcription factor
TF locus tag:	SE0931
Regulator family:	CodY
Regulation mode:	repressor
Biological process:	Amino acid metabolism
Effector:	Branched-chain amino acids
Regulog:	CodY - Staphylococcaceae
Statistics of regulated genes:
- Genes	114
- Operons	53
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 516 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - CodY
By effector - Branched-chain amino acids
By pathway - Amino acid metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -80 Score: 4.1 Sequence: ATTTGTTTAACAATT Locus tag: SE2018 Name: opuCA Funciton: glycine betaine/carnitine/choline ABC transporter opuCA Locus tag: SE2017 Name: opuCB Funciton: glycine betaine/carnitine/choline ABC transporter opuCB Locus tag: SE2016 Name: opuCC Funciton: glycine betaine/carnitine/choline ABC transporter opuCC Locus tag: SE2015 Name: opuCD Funciton: glycine betaine/carnitine/choline ABC transporter opuCD
	SE2018	opuCA	glycine betaine/carnitine/choline ABC transporter opuCA
	SE2017	opuCB	glycine betaine/carnitine/choline ABC transporter opuCB
	SE2016	opuCC	glycine betaine/carnitine/choline ABC transporter opuCC
	SE2015	opuCD	glycine betaine/carnitine/choline ABC transporter opuCD
Position: -63 Score: 4.9 Sequence: ATATTTCTGAAAATT Locus tag: SE0680 Name: oppB Funciton: oligopeptide ABC transporter permease protein OppB Locus tag: SE0681 Name: oppC Funciton: oligopeptide transport system permease protein OppC Locus tag: SE0682 Name: oppD Funciton: oligopeptide ABC transporter ATP-binding protein OppD Locus tag: SE0683 Name: oppF Funciton: oligopeptide ABC transporter ATP-binding protein OppF Locus tag: SE0684 Name: oppA Funciton: oligopeptide ABC transporter OppA oligopeptide-binding protein
	SE0680	oppB	oligopeptide ABC transporter permease protein OppB
	SE0681	oppC	oligopeptide transport system permease protein OppC
	SE0682	oppD	oligopeptide ABC transporter ATP-binding protein OppD
	SE0683	oppF	oligopeptide ABC transporter ATP-binding protein OppF
	SE0684	oppA	oligopeptide ABC transporter OppA oligopeptide-binding protein
Position: -61 Score: 4.4 Sequence: TTATTTCAGAAAATT Position: -52 Score: 4.5 Sequence: AAAATTCTAACTATT Locus tag: SE2122 Name: mtnE Funciton: transaminase MtnE involved in methionine biosynthesis via salvage pathway Locus tag: SE2121 Name: ddh2 Funciton: D-lactate dehydrogenase
	SE2122	mtnE	transaminase MtnE involved in methionine biosynthesis via salvage pathway
	SE2121	ddh2	D-lactate dehydrogenase
Position: -233 Score: 4.8 Sequence: AATAATTAGAAAATT Position: -224 Score: 4.5 Sequence: AAAATTTAGACTATT Locus tag: SE0011 Name: metX Funciton: homoserine-o-acetyltransferase
	SE0011	metX	homoserine-o-acetyltransferase
Position: -303 Score: 4.2 Sequence: TATTATTAAAATATT Position: -294 Score: 4.7 Sequence: AATATTTAAAATAAT Locus tag: SE1902 Name: metT Funciton: methionine transporter MetT
	SE1902	metT	methionine transporter MetT
Position: -275 Score: 4.6 Sequence: ATTTGTTAGAAAATT Position: -266 Score: 4.4 Sequence: AAAATTTAAAATAAT Locus tag: SE0600 Name: metN Funciton: Methionine ABC transporter, ATP-binding protein Locus tag: SE0601 Name: metP Funciton: Methionine ABC transporter, permease protein Locus tag: SE0602 Name: metQ Funciton: Methionine ABC transporter, methionine-binding lipoprotein
	SE0600	metN	Methionine ABC transporter, ATP-binding protein
	SE0601	metP	Methionine ABC transporter, permease protein
	SE0602	metQ	Methionine ABC transporter, methionine-binding lipoprotein
Position: -533 Score: 5.1 Sequence: AATTTTCAGAAAAAT Locus tag: SE2379 Name: metI Funciton: cystathionine gamma-synthase Locus tag: SE2380 Name: metC Funciton: cystathionine beta-lyase Locus tag: SE2381 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase protein Locus tag: SE2382 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase Locus tag: SE2383 Name: mdh Funciton: hypothetical metal-dependent hydrolase
	SE2379	metI	cystathionine gamma-synthase
	SE2380	metC	cystathionine beta-lyase
	SE2381	metF	5,10-methylenetetrahydrofolate reductase protein
	SE2382	metE	5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase
	SE2383	mdh	hypothetical metal-dependent hydrolase
Position: -46 Score: 5.2 Sequence: AATTTTCTAAAAATT Locus tag: SE1074 Name: asd Funciton: aspartate semialdehyde dehydrogenase Locus tag: SE1075 Name: dapA Funciton: dihydrodipicolinate synthase Locus tag: SE1076 Name: dapB Funciton: dihydrodipicolinate reductase Locus tag: SE1077 Name: dapD Funciton: tetrahydrodipicolinate acetyltransferase Locus tag: SE1078 Name: ykuR Funciton: hippurate hydrolase Locus tag: SE1079 Name: dapX Funciton: putative alanine racemase Locus tag: SE1080 Name: lysA Funciton: diaminopimelate decarboxylase
	SE1074	asd	aspartate semialdehyde dehydrogenase
	SE1075	dapA	dihydrodipicolinate synthase
	SE1076	dapB	dihydrodipicolinate reductase
	SE1077	dapD	tetrahydrodipicolinate acetyltransferase
	SE1078	ykuR	hippurate hydrolase
	SE1079	dapX	putative alanine racemase
	SE1080	lysA	diaminopimelate decarboxylase
Position: -149 Score: 5 Sequence: AATATTCAGAAATTT Locus tag: SE0995 Name: ltaE Funciton: low specificity L-threonine aldolase
	SE0995	ltaE	low specificity L-threonine aldolase
Position: -142 Score: 4.1 Sequence: AATTGTTAAATTTTT Position: -133 Score: 4.6 Sequence: ATTTTTCTGATATTT Locus tag: SE1016 Name: katA Funciton: catalase
	SE1016	katA	catalase
Position: -99 Score: 4.1 Sequence: TCTATTTTGAATATT Position: -90 Score: 5.2 Sequence: AATATTTAGAAAATT Locus tag: SE0318 Name: ilvE Funciton: branched-chain amino acid aminotroansferase
	SE0318	ilvE	branched-chain amino acid aminotroansferase
Position: -50 Score: 4.9 Sequence: ATTATTTTGAAAATT Locus tag: SE1657 Name: ilvC Funciton: alpha-keto-beta-hydroxylacil reductoisomerase Locus tag: SE1658 Name: leuA Funciton: 2-isopropylmalate synthase Locus tag: SE1659 Name: leuB Funciton: 3-isopropylmalate dehydrogenase Locus tag: SE1660 Name: leuC Funciton: 3-isopropylmalate dehydratase large subunit Locus tag: SE1661 Name: leuD Funciton: 3-isopropylmalate dehydratase small subunit Locus tag: SE1662 Name: ilvA Funciton: thereonine dehydratase
	SE1657	ilvC	alpha-keto-beta-hydroxylacil reductoisomerase
	SE1658	leuA	2-isopropylmalate synthase
	SE1659	leuB	3-isopropylmalate dehydrogenase
	SE1660	leuC	3-isopropylmalate dehydratase large subunit
	SE1661	leuD	3-isopropylmalate dehydratase small subunit
	SE1662	ilvA	thereonine dehydratase
Position: -330 Score: 5.2 Sequence: AATTTTTAGAAAATT Position: -321 Score: 4.1 Sequence: AAAATTCTAAATTTA Locus tag: SE1654 Name: ilvD Funciton: dihydroxy-acid dehydratase Locus tag: SE1655 Name: ilvB Funciton: acetolactate synthase large subunit Locus tag: SE1656 Name: ilvH Funciton: acetolactate synthase small subunit
	SE1654	ilvD	dihydroxy-acid dehydratase
	SE1655	ilvB	acetolactate synthase large subunit
	SE1656	ilvH	acetolactate synthase small subunit
Position: -170 Score: 4.7 Sequence: AAAAATCAGAAAATT Locus tag: SE1009 Name: hom Funciton: homoserine dehydrogenase Locus tag: SE1010 Name: thrC Funciton: threonine synthase Locus tag: SE1011 Name: thrB Funciton: homoserine kinase Locus tag: SE1012 Name: SA1167 Funciton: putative hydrolase of the HAD superfamily
	SE1009	hom	homoserine dehydrogenase
	SE1010	thrC	threonine synthase
	SE1011	thrB	homoserine kinase
	SE1012	SA1167	putative hydrolase of the HAD superfamily
Position: -113 Score: 4.6 Sequence: AATTGTAAGAAAATT Position: -102 Score: 4.2 Sequence: AATTGTGTAAAAATT Locus tag: SE1731 Name: hmrA Funciton: N-acyl-L-amino acid amidohydrolase Locus tag: SE1730 Name: SA1934 Funciton: hypothetical protein
	SE1731	hmrA	N-acyl-L-amino acid amidohydrolase
	SE1730	SA1934	hypothetical protein
Position: -115 Score: 5.1 Sequence: AATTTTCTGAAAAAT Locus tag: SE0270 Name: hisZ Funciton: ATP phosphoribosyltransferase regulatory subunit Locus tag: SE0271 Name: hisG Funciton: ATP phosphoribosyltransferase Locus tag: SE0272 Name: hisD Funciton: histidinol dehydrogenase Locus tag: SE0273 Name: hisB Funciton: imidazoleglycerol-phosphate dehydratase Locus tag: SE0274 Name: hisH Funciton: imidazole glycerol phosphate synthase glutamine amidotransferase subunit Locus tag: SE0275 Name: hisA Funciton: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Locus tag: SE0276 Name: hisF Funciton: imidazoleglycerol-phosphate synthase Locus tag: SE0277 Name: hisI Funciton: histidine biosynthesis bifunctional protein HisIE
	SE0270	hisZ	ATP phosphoribosyltransferase regulatory subunit
	SE0271	hisG	ATP phosphoribosyltransferase
	SE0272	hisD	histidinol dehydrogenase
	SE0273	hisB	imidazoleglycerol-phosphate dehydratase
	SE0274	hisH	imidazole glycerol phosphate synthase glutamine amidotransferase subunit
	SE0275	hisA	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
	SE0276	hisF	imidazoleglycerol-phosphate synthase
	SE0277	hisI	histidine biosynthesis bifunctional protein HisIE
Position: -171 Score: 5 Sequence: AATTTTCTGACAATT Locus tag: SE2313 Name: gltC Funciton: transcription activator of glutamate synthase operon
	SE2313	gltC	transcription activator of glutamate synthase operon
Position: -35 Score: 5 Sequence: AATTGTCAGAAAATT Locus tag: SE2312 Name: gltB Funciton: glutamate synthase large subunit Locus tag: SE2311 Name: gltD Funciton: NNADPH-dependent glutamate synthase beta subunit
	SE2312	gltB	glutamate synthase large subunit
	SE2311	gltD	NNADPH-dependent glutamate synthase beta subunit
Position: -194 Score: 4.8 Sequence: AAATGTCTGAAAATT Position: -185 Score: 4.7 Sequence: AAAATTTTAAAAATT Locus tag: SE0986 Name: glnR Funciton: HTH-type transcriptional regulator GlnR Locus tag: SE0987 Name: glnA Funciton: glutamine synthetase
	SE0986	glnR	HTH-type transcriptional regulator GlnR
	SE0987	glnA	glutamine synthetase
Position: -164 Score: 4.6 Sequence: AATATTCTAAATTAT Position: -155 Score: 4.6 Sequence: AATTATCAGAAAATA Locus tag: SE2148 Name: gabT Funciton: 4-aminobutyrate aminotransferase
	SE2148	gabT	4-aminobutyrate aminotransferase
Position: -69 Score: 4.7 Sequence: ATTATTCTGACAATT Locus tag: SE2181 Name: cysH Funciton: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase
	SE2181	cysH	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase
Position: -147 Score: 4.7 Sequence: AATATTCTGACATTT Locus tag: SE0731 Name: comK Funciton: competence transcription factor
	SE0731	comK	competence transcription factor
Position: -173 Score: 4.4 Sequence: AATATTAAAAATTTT Locus tag: SE0217 Name: brnQ1 Funciton: branched-chain amino acid transport system
	SE0217	brnQ1	branched-chain amino acid transport system
Position: -87 Score: 5.1 Sequence: AATTTTCTGAAATTT Locus tag: SE1090 Name: braB Funciton: branched-chain amino acid transport system
	SE1090	braB	branched-chain amino acid transport system
Position: -69 Score: 4.9 Sequence: ACTTTTCAGAAAATT Locus tag: SE2219 Name: aur Funciton: zinc metalloproteinase aureolysin
	SE2219	aur	zinc metalloproteinase aureolysin
Position: -138 Score: 4 Sequence: TCTTTTTTAAATATT Locus tag: SE1155 Name: aroC Funciton: chorismate synthase Locus tag: SE1154 Name: aroB Funciton: 3-dehydroquinate synthase Locus tag: SE1153 Name: aroA Funciton: 3-phosphoshikimate 1-carboxyvinyltransferase Locus tag: SE1152 Name: SA1296 Funciton: hypothetical protein Locus tag: SE1151 Name: SA1295 Funciton: hypothetical protein Locus tag: SE1150 Name: SA1294 Funciton: hypothetical protein Locus tag: SE1149 Name: null Funciton: hypothetical protein Locus tag: SE1148 Name: SA1293 Funciton: hypothetical protein
	SE1155	aroC	chorismate synthase
	SE1154	aroB	3-dehydroquinate synthase
	SE1153	aroA	3-phosphoshikimate 1-carboxyvinyltransferase
	SE1152	SA1296	hypothetical protein
	SE1151	SA1295	hypothetical protein
	SE1150	SA1294	hypothetical protein
	SE1149		hypothetical protein
	SE1148	SA1293	hypothetical protein
Position: -180 Score: 4.5 Sequence: AATTTACAGAAATTT Position: -171 Score: 4.3 Sequence: AAATTTTAAAATATA Locus tag: SE0657 Name: argG Funciton: argininosuccinate synthase Locus tag: SE0656 Name: argH Funciton: argininosuccinate lyase
	SE0657	argG	argininosuccinate synthase
	SE0656	argH	argininosuccinate lyase
Position: -93 Score: 4.9 Sequence: ATATTTCTGAAAATT Locus tag: SE2004 Name: aapA Funciton: D-serine/D-alanine/glycine transporter
	SE2004	aapA	D-serine/D-alanine/glycine transporter
Position: -251 Score: 4.4 Sequence: AATTATCTGATTTTT Position: -242 Score: 4.6 Sequence: ATTTTTCTAATTATT Position: -35 Score: 4.4 Sequence: GTTATTCTGAAAATT Locus tag: SE1047 Name: tyrA Funciton: prephenate dehydrogenase
	SE1047	tyrA	prephenate dehydrogenase
Position: -431 Score: 4.6 Sequence: AATAATTAGAAAAAT Position: -422 Score: 4.4 Sequence: AAAAATCAGATAATT Locus tag: SE1048 Name: trpE Funciton: anthranilate synthase component I Locus tag: SE1049 Name: trpG Funciton: anthranilate synthase component II Locus tag: SE1050 Name: trpD Funciton: anthranilate phosphoribosyltransferase Locus tag: SE1051 Name: trpC Funciton: indole-3-glycerol phosphate synthase Locus tag: SE1052 Name: trpF Funciton: phosphoriborylanthranilate isomerase Locus tag: SE1053 Name: trpB Funciton: tryptophan synthase beta subunit Locus tag: SE1054 Name: trpA Funciton: tryptophan synthase alpha subunit
	SE1048	trpE	anthranilate synthase component I
	SE1049	trpG	anthranilate synthase component II
	SE1050	trpD	anthranilate phosphoribosyltransferase
	SE1051	trpC	indole-3-glycerol phosphate synthase
	SE1052	trpF	phosphoriborylanthranilate isomerase
	SE1053	trpB	tryptophan synthase beta subunit
	SE1054	trpA	tryptophan synthase alpha subunit
Position: -107 Score: 4 Sequence: CTTTTTTTAAATTTT Position: -98 Score: 5.2 Sequence: AATTTTTTGAAAATT Locus tag: SE0509 Name: tppB Funciton: di-tripepride ABC transporter
	SE0509	tppB	di-tripepride ABC transporter
Position: -33 Score: 4.7 Sequence: AATTTTCTGATTTTT Locus tag: SE1008 Name: thrA Funciton: aspartokinase III
	SE1008	thrA	aspartokinase III
Position: -101 Score: 4.4 Sequence: AATAATTTAATAATT Locus tag: SE1240 Name: sodA Funciton: superoxide dismutase SodA
	SE1240	sodA	superoxide dismutase SodA
Position: -32 Score: 5.1 Sequence: AATTTTCAGATAATT Locus tag: SE2356 Name: SE2356 Funciton: 2-oxo-hepta-3-ene-1,7-dioate hydratase
	SE2356	SE2356	2-oxo-hepta-3-ene-1,7-dioate hydratase
Position: -179 Score: 5 Sequence: AAATTTCTGAATATT Locus tag: SE0996 Name: SAS040 Funciton: conserved hypothetical protein Locus tag: SE0997 Name: SA1155 Funciton: putative cardiolipin synthetase
	SE0996	SAS040	conserved hypothetical protein
	SE0997	SA1155	putative cardiolipin synthetase
Position: -139 Score: 4.8 Sequence: AATTTTAAAAAAATT Locus tag: SE0357 Name: SE0357 Funciton: hypothetical protein Locus tag: SE0356 Name: SE0356 Funciton: hypothetical protein
	SE0357	SE0357	hypothetical protein
	SE0356	SE0356	hypothetical protein
Position: -125 Score: 4.6 Sequence: TATTTTCTGATAATT Position: -116 Score: 4.6 Sequence: ATAATTTAGAATATT Locus tag: SE2150 Name: SA2398 Funciton: hypothetical protein
	SE2150	SA2398	hypothetical protein
Position: -165 Score: 4.8 Sequence: ATTTTTCAGAATTTT Position: -156 Score: 4.2 Sequence: AATTTTTAGACAAAA Locus tag: SE2147 Name: SA2396 Funciton: putative amino acid transporter
	SE2147	SA2396	putative amino acid transporter
Position: -172 Score: 5.1 Sequence: AATTTTCAGAAAAAT Locus tag: SE2129 Name: SA2357 Funciton: putative regulatory protein
	SE2129	SA2357	putative regulatory protein
Position: -218 Score: 4.6 Sequence: ATTTTTCTGAAATAT Locus tag: SE2032 Name: SA2260 Funciton: putative short chain dehydrogenase
	SE2032	SA2260	putative short chain dehydrogenase
Position: -246 Score: 5.2 Sequence: AATTTTCTAAAAATT Locus tag: SE2010 Name: SA2233 Funciton: integral membrane efflux protein
	SE2010	SA2233	integral membrane efflux protein
Position: -98 Score: 4.4 Sequence: AATTGTAAAAATATT Locus tag: SE1892 Name: SA2109 Funciton: probable amino-acid or metabolite transporter
	SE1892	SA2109	probable amino-acid or metabolite transporter
Position: -54 Score: 5 Sequence: AATATTCAGAATTTT Locus tag: SE1400 Name: SA1544 Funciton: putative phosphoserine transaminase Locus tag: SE1401 Name: serA Funciton: D-3-phosphoglycerate dehydrogenase
	SE1400	SA1544	putative phosphoserine transaminase
	SE1401	serA	D-3-phosphoglycerate dehydrogenase
Position: -66 Score: 4.6 Sequence: AATATTTTGATAAAT Locus tag: SE1218 Name: SA1364 Funciton: putative sulfurtransferase
	SE1218	SA1364	putative sulfurtransferase
Position: -108 Score: 4.6 Sequence: ATTTATCAAAATATT Locus tag: SE1217 Name: SA1363 Funciton: Lipoate-protein ligase A
	SE1217	SA1363	Lipoate-protein ligase A
Position: -82 Score: 4.7 Sequence: AAATGTCAGAATATT Locus tag: SE0729 Name: SA0883 Funciton: hypothetical protein
	SE0729	SA0883	hypothetical protein
Position: -206 Score: 5 Sequence: AAAATTCAGAATATT Position: -197 Score: 4.1 Sequence: AATATTTAAATTTAT Locus tag: SE0420 Name: SA0601 Funciton: hypothetical protein
	SE0420	SA0601	hypothetical protein
Position: -114 Score: 5.1 Sequence: AATTATCTGAAAATT Locus tag: SE2355 Name: SA0367 Funciton: putative NADPH-flavin oxidoreductase
	SE2355	SA0367	putative NADPH-flavin oxidoreductase
Position: -210 Score: 5.1 Sequence: ATTTTTCTGAAAATT Locus tag: SE2378 Name: SA0348 Funciton: putative transcriptional regulator
	SE2378	SA0348	putative transcriptional regulator
Position: -112 Score: 4.6 Sequence: AAATATCAGAAAAAT Position: -103 Score: 4.1 Sequence: AAAAATTTAACAATT Locus tag: SE1015 Name: rocC Funciton: amino acid permease
	SE1015	rocC	amino acid permease
Position: -40 Score: 4.1 Sequence: TATTATCTAATTATT Position: -31 Score: 4.9 Sequence: ATTATTTAGAAAATT Locus tag: SE0813 Name: pycA Funciton: pyruvate carboxylase
	SE0813	pycA	pyruvate carboxylase
Position: -59 Score: 4.1 Sequence: ACTATTTAAACAATT Locus tag: SE0747 Name: patA Funciton: putative aminotransferase A
	SE0747	patA	putative aminotransferase A
Position: -43 Score: 4 Sequence: TATTTTTTAACAAAT Locus tag: SE0222 Name: opuCA Funciton: glycine betaine/carnitine/choline ABC transporter opuCA Locus tag: SE0223 Name: opuCB Funciton: glycine betaine/carnitine/choline ABC transporter opuCB Locus tag: SE0224 Name: opuCC Funciton: glycine betaine/carnitine/choline ABC transporter opuCC Locus tag: SE0225 Name: opuCD Funciton: glycine betaine/carnitine/choline ABC transporter opuCD Locus tag: SE0226 Name: SE0226 Funciton: putative esterase
	SE0222	opuCA	glycine betaine/carnitine/choline ABC transporter opuCA
	SE0223	opuCB	glycine betaine/carnitine/choline ABC transporter opuCB
	SE0224	opuCC	glycine betaine/carnitine/choline ABC transporter opuCC
	SE0225	opuCD	glycine betaine/carnitine/choline ABC transporter opuCD
	SE0226	SE0226	putative esterase

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of CodY in Staphylococcus epidermidis ATCC 12228

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --