Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CodY in Staphylococcus capitis SK14

Properties
Regulator type: Transcription factor
TF locus tag: STACA0001_0565
Regulator family: CodY
Regulation mode: repressor
Biological process: Amino acid metabolism
Effector: Branched-chain amino acids
Regulog: CodY - Staphylococcaceae
Statistics of regulated genes:
- Genes 102
- Operons 57
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 516 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -101
Score: 4.4
Sequence: TTTATTTTGAATATT
Position: -92
Score: 4.7
Sequence: AATATTTAGAAAACT
Locus tag: STACA0001_0476
Name: ilvE
Funciton: branched-chain amino acid aminotransferase
ilvE
branched-chain amino acid aminotransferase

Position: -49
Score: 5.2
Sequence: AATATTTTGAAAATT
Position: -40
Score: 4.3
Sequence: AAAATTAAGAATTTT
Locus tag: STACA0001_0523
Name: ilvC
Funciton: alpha-keto-beta-hydroxylacil reductoisomerase
Locus tag: STACA0001_0522
Name: leuA
Funciton: 2-isopropylmalate synthase
Locus tag: STACA0001_0521
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase
Locus tag: STACA0001_0520
Name: leuC
Funciton: 3-isopropylmalate dehydratase, large subunit
Locus tag: STACA0001_0519
Name: leuD
Funciton: 3-isopropylmalate dehydratase, small subunit
Locus tag: STACA0001_0518
Name: ilvA
Funciton: threonine dehydratase
ilvC
alpha-keto-beta-hydroxylacil reductoisomerase
leuA
2-isopropylmalate synthase
leuB
3-isopropylmalate dehydrogenase
leuC
3-isopropylmalate dehydratase, large subunit
leuD
3-isopropylmalate dehydratase, small subunit
ilvA
threonine dehydratase

Position: -327
Score: 4.9
Sequence: AATTGTTAGAAAATT
Locus tag: STACA0001_0526
Name: ilvD
Funciton: dihydroxy-acid dehydratase
Locus tag: STACA0001_0525
Name: ilvB
Funciton: acetolactate synthase large subunit
Locus tag: STACA0001_0524
Name: ilvH
Funciton: acetolactate synthase small subunit
ilvD
dihydroxy-acid dehydratase
ilvB
acetolactate synthase large subunit
ilvH
acetolactate synthase small subunit

Position: 4
Score: 4.4
Sequence: AATTTTTTAACTTTT
Locus tag: STACA0001_0088
Name: icaA
Funciton: intercellular adhesion protein A
Locus tag: STACA0001_0087
Name: icaD
Funciton: intercellular adhesion protein D
Locus tag: STACA0001_0086
Name: icaB
Funciton: intercellular adhesion protein B
Locus tag: STACA0001_0085
Name: icaC
Funciton: intercellular adhesion protein C
icaA
intercellular adhesion protein A
icaD
intercellular adhesion protein D
icaB
intercellular adhesion protein B
icaC
intercellular adhesion protein C

Position: -170
Score: 4.7
Sequence: AAAAATCAGAAAATT
Position: -91
Score: 4.3
Sequence: AAAATTAAGAATAAT
Locus tag: STACA0001_1571
Name: hom
Funciton: homoserine dehydrogenase
Locus tag: STACA0001_1572
Name: thrC
Funciton: threonine synthase
Locus tag: STACA0001_1573
Name: thrB
Funciton: homoserine kinase
Locus tag: STACA0001_1574
Name: SA1167
Funciton: putative hydrolase of the HAD superfamily
hom
homoserine dehydrogenase
thrC
threonine synthase
thrB
homoserine kinase
SA1167
putative hydrolase of the HAD superfamily

Position: -235
Score: 4.6
Sequence: AATTGTAAGAAAATT
Locus tag: STACA0001_0837
Name: hmrA
Funciton: N-acyl-L-amino acid amidohydrolase
Locus tag: STACA0001_0836
Name: SA1934
Funciton: hypothetical protein
hmrA
N-acyl-L-amino acid amidohydrolase
SA1934
hypothetical protein

Position: -179
Score: 5
Sequence: AATTTTCTGACAATT
Position: -41
Score: 4.6
Sequence: AAATTTTAGAATTTT
Locus tag: STACA0001_1493
Name: gltC
Funciton: transcription activator of glutamate synthase operon
gltC
transcription activator of glutamate synthase operon

Position: -174
Score: 4.6
Sequence: AAAATTCTAAAATTT
Position: -36
Score: 5
Sequence: AATTGTCAGAAAATT
Locus tag: STACA0001_1494
Name: gltB
Funciton: glutamate synthase large subunit
Locus tag: STACA0001_1495
Name: gltD
Funciton: NADPH-dependent glutamate synthase beta subunit
gltB
glutamate synthase large subunit
gltD
NADPH-dependent glutamate synthase beta subunit

Position: -202
Score: 4.3
Sequence: TTTTGTCAGAAAATT
Position: -191
Score: 4.1
Sequence: AATTATAAAATTATT
Position: -150
Score: 4.2
Sequence: ATTAATTAAAAATTT
Locus tag: STACA0001_1553
Name: glnR
Funciton: HTH-type transcriptional regulator GlnR
Locus tag: STACA0001_1554
Name: glnA
Funciton: glutamine synthetase
glnR
HTH-type transcriptional regulator GlnR
glnA
glutamine synthetase

Position: -175
Score: 4.7
Sequence: AATATTTTAATAATT
Position: -166
Score: 4.3
Sequence: ATAATTCAGAAAATA
Locus tag: STACA0001_0892
Name: gabT
Funciton: 4-aminobutyrate aminotransferase
gabT
4-aminobutyrate aminotransferase

Position: -72
Score: 4.7
Sequence: ATTATTCTGACAATT
Locus tag: STACA0001_1812
Name: cysH
Funciton: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase
cysH
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase

Position: -151
Score: 4.7
Sequence: AATATTCTGACATTT
Locus tag: STACA0001_0106
Name: comK
Funciton: competence transcription factor
comK
competence transcription factor

Position: -81
Score: 4.7
Sequence: TTTTTTCTGAAAATT
Locus tag: STACA0001_0024
Name: brnQ1
Funciton: branched-chain amino acid transport system
brnQ1
branched-chain amino acid transport system

Position: -85
Score: 4.7
Sequence: AATTTTCTGAAATTA
Locus tag: STACA0001_1652
Name: braB
Funciton: branched-chain amino acid transport system
braB
branched-chain amino acid transport system

Position: -30
Score: 4.2
Sequence: CTTTTTCAAAAATTT
Position: 7
Score: 4.4
Sequence: ATTTTTCAAAATATG
Locus tag: STACA0001_1850
Name: aur
Funciton: zinc metalloproteinase aureolysin
aur
zinc metalloproteinase aureolysin

Position: 6
Score: 4.2
Sequence: AAAATTATTAAAATT
Locus tag: STACA0001_0720
Name: artQ
Funciton: Arginine ABC transport system ArtQ
Locus tag: STACA0001_0719
Name: artM
Funciton: Arginine ABC transport system ATP-binding protein ArtM
artQ
Arginine ABC transport system ArtQ
artM
Arginine ABC transport system ATP-binding protein ArtM

Position: -33
Score: 5
Sequence: AAAATTCTGAAAATT
Locus tag: STACA0001_0165
Name: argG
Funciton: argininosuccinate synthase
Locus tag: STACA0001_0166
Name: argH
Funciton: argininosuccinate lyase
argG
argininosuccinate synthase
argH
argininosuccinate lyase

Position: -110
Score: 4.3
Sequence: ATTTTTCAAAAATCT
Locus tag: STACA0001_0627
Name: acuA
Funciton: acetoin utilization protein AcuA
Locus tag: STACA0001_0628
Name: acuC
Funciton: acetoin utilization protein AcuC
acuA
acetoin utilization protein AcuA
acuC
acetoin utilization protein AcuC

Position: -78
Score: 4.3
Sequence: AGATTTTTGAAAAAT
Locus tag: STACA0001_0626
Name: acsA
Funciton: acetyl-CoA synthetase
acsA
acetyl-CoA synthetase

Position: -166
Score: 4.8
Sequence: AATTTTTTGATTATT
Position: -157
Score: 4.7
Sequence: ATTATTCTAAAAAAT
Locus tag: STACA0001_1050
Name: aapA
Funciton: D-serine/D-alanine/glycine transporter
aapA
D-serine/D-alanine/glycine transporter

Position: -131
Score: 4.3
Sequence: TATTTTCTGAATTAT
Position: -122
Score: 4.7
Sequence: AATTATTAAAATATT
Locus tag: STACA0001_0891
Name: SA2398
Funciton: hypothetical protein
SA2398
hypothetical protein

Position: -295
Score: 4.3
Sequence: AATTTGTAAAATATT
Position: -160
Score: 4.8
Sequence: ATTTTTCAGAATTTT
Position: -151
Score: 4.2
Sequence: AATTTTTAGACAAAA
Locus tag: STACA0001_0893
Name: SA2396
Funciton: putative amino acid transporter
SA2396
putative amino acid transporter

Position: -184
Score: 4.6
Sequence: AATTATCTAAATTTT
Position: -175
Score: 4.4
Sequence: AATTTTCTGAAAACG
Locus tag: STACA0001_0926
Name: SA2357
Funciton: putative regulatory protein
SA2357
putative regulatory protein

Position: -78
Score: 5.1
Sequence: AAATTTCAGAAAATT
Locus tag: STACA0001_1021
Name: SA2261
Funciton: putative p-aminobenzoyl-glutamate transporter
SA2261
putative p-aminobenzoyl-glutamate transporter

Position: -218
Score: 5.1
Sequence: AATTTTCTGAAATTT
Locus tag: STACA0001_1022
Name: SA2260
Funciton: putative short chain dehydrogenase
SA2260
putative short chain dehydrogenase

Position: -252
Score: 5.2
Sequence: AATTTTCTAAAAATT
Locus tag: STACA0001_1042
Name: SA2233
Funciton: integral membrane efflux protein
SA2233
integral membrane efflux protein

Position: -181
Score: 5.1
Sequence: AATTTTCAGAAAAAT
Position: -101
Score: 4.1
Sequence: AATTGTAAAAATTTT
Locus tag: STACA0001_1171
Name: SA2109
Funciton: probable amino-acid or metabolite transporter
SA2109
probable amino-acid or metabolite transporter

Position: -53
Score: 5.2
Sequence: AATATTCAGAATATT
Locus tag: STACA0001_0615
Name: SA1544
Funciton: putative phosphoserine transaminase
Locus tag: STACA0001_0616
Name: serA
Funciton: D-3-phosphoglycerate dehydrogenase
SA1544
putative phosphoserine transaminase
serA
D-3-phosphoglycerate dehydrogenase

Position: -66
Score: 4.6
Sequence: AATATTTTGATAAAT
Locus tag: STACA0001_1771
Name: SA1364
Funciton: putative sulfurtransferase
SA1364
putative sulfurtransferase

Position: -109
Score: 4.6
Sequence: ATTTATCAAAATATT
Locus tag: STACA0001_1770
Name: SA1363
Funciton: Lipoate-protein ligase A
SA1363
Lipoate-protein ligase A

Position: -83
Score: 4.7
Sequence: AAATGTCAGAATATT
Locus tag: STACA0001_0107
Name: SA0883
Funciton: hypothetical protein
SA0883
hypothetical protein

Position: -200
Score: 4.6
Sequence: ATTAATTAGAAAATT
Position: -142
Score: 4.3
Sequence: AATTTTAAGTAAATT
Position: -98
Score: 4.2
Sequence: ATAATTTTGAAAATA
Locus tag: STACA0001_0358
Name: SA0626
Funciton: hypothetical protein
SA0626
hypothetical protein

Position: -211
Score: 5
Sequence: AAAATTCAGAATATT
Locus tag: STACA0001_0382
Name: SA0601
Funciton: hypothetical protein
SA0601
hypothetical protein

Position: -145
Score: 4.8
Sequence: AAATATCTGAAAATT
Locus tag: STACA0001_1449
Name: SA0367
Funciton: putative NADPH-flavin oxidoreductase
SA0367
putative NADPH-flavin oxidoreductase

Position: -209
Score: 4.9
Sequence: ACTTTTCTGAAAATT
Position: -75
Score: 4.8
Sequence: AATTTTTAAAATAAT
Locus tag: STACA0001_1417
Name: SA0348
Funciton: putative transcriptional regulator
SA0348
putative transcriptional regulator

Position: -112
Score: 5.1
Sequence: AAATTTCAGAAAATT
Position: -102
Score: 4.7
Sequence: AAATTTTTAAATATT
Locus tag: STACA0001_1576
Name: rocC
Funciton: lamino acid permease
rocC
lamino acid permease

Position: -42
Score: 4.6
Sequence: ATTAGTTAGAAAATT
Position: -33
Score: 4.4
Sequence: AAAATTCAAAAAATA
Locus tag: STACA0001_2249
Name: pycA
Funciton: pyruvate carboxylase
pycA
pyruvate carboxylase

Position: -58
Score: 4.1
Sequence: ACTATTTTAACAATT
Locus tag: STACA0001_2317
Name: patA
Funciton: putative aminotransferase A
patA
putative aminotransferase A

Position: -145
Score: 4.3
Sequence: CATATTCAAAATTTT
Locus tag: STACA0001_1036
Name: opuCA
Funciton: glycine betaine/carnitine/choline ABC transporter opuCA
Locus tag: STACA0001_1037
Name: opuCB
Funciton: glycine betaine/carnitine/choline ABC transporter opuCB
Locus tag: STACA0001_1038
Name: opuCC
Funciton: glycine betaine/carnitine/choline ABC transporter opuCC
Locus tag: STACA0001_1039
Name: opuCD
Funciton: glycine betaine/carnitine/choline ABC transporter opuCD
opuCA
glycine betaine/carnitine/choline ABC transporter opuCA
opuCB
glycine betaine/carnitine/choline ABC transporter opuCB
opuCC
glycine betaine/carnitine/choline ABC transporter opuCC
opuCD
glycine betaine/carnitine/choline ABC transporter opuCD

Position: -36
Score: 4.2
Sequence: AATATACATAATATT
Position: -27
Score: 4.6
Sequence: AATATTCTGAAAAAA
Locus tag: STACA0001_0146
Name: oppB
Funciton: oligopeptide transport system permease protein OppB
Locus tag: STACA0001_0145
Name: oppC
Funciton: oligopeptide ABC transporter permease protein OppC
oppB
oligopeptide transport system permease protein OppB
oppC
oligopeptide ABC transporter permease protein OppC

Position: -212
Score: 4.2
Sequence: AAATGTTTGAAAATA
Position: -93
Score: 4.6
Sequence: ACTTATCTGAAAATT
Locus tag: STACA0001_0934
Name: mtnE
Funciton: transaminase MtnE involved in methionine biosynthesis via salvage pathway
Locus tag: STACA0001_0935
Name: ddh2
Funciton: D-lactate dehydrogenase
mtnE
transaminase MtnE involved in methionine biosynthesis via salvage pathway
ddh2
D-lactate dehydrogenase

Position: -236
Score: 4.6
Sequence: ATTAATTAGAAAATT
Position: -227
Score: 4.6
Sequence: AAAATTCAGACTATT
Locus tag: STACA0001_1363
Name: metX
Funciton: homoserine-o-acetyltransferase
metX
homoserine-o-acetyltransferase

Position: -272
Score: 4.6
Sequence: ATTTGTTAGAAAATT
Position: -263
Score: 4.4
Sequence: AAAATTTAAAATAAT
Locus tag: STACA0001_0218
Name: metN
Funciton: Methionine ABC transporter, ATP-binding protein
Locus tag: STACA0001_0217
Name: metP
Funciton: Methionine ABC transporter, permease protein
Locus tag: STACA0001_0216
Name: metQ
Funciton: Methionine ABC transporter, methionine-binding lipoprotein
metN
Methionine ABC transporter, ATP-binding protein
metP
Methionine ABC transporter, permease protein
metQ
Methionine ABC transporter, methionine-binding lipoprotein

Position: -553
Score: 4.9
Sequence: AATTTTCAGAAAAGT
Locus tag: STACA0001_1416
Name: metI
Funciton: cystathionine gamma-synthase
Locus tag: STACA0001_1415
Name: metC
Funciton: cystathionine beta-lyase
Locus tag: STACA0001_1414
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase protein
Locus tag: STACA0001_1413
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase
Locus tag: STACA0001_1412
Name: mdh
Funciton: hypothetical metal-dependent hydrolase
metI
cystathionine gamma-synthase
metC
cystathionine beta-lyase
metF
5,10-methylenetetrahydrofolate reductase protein
metE
5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase
mdh
hypothetical metal-dependent hydrolase

Position: -43
Score: 4.7
Sequence: AATTATCAGAATTTT
Locus tag: STACA0001_0229
Name: lysE
Funciton: lysine exporter protein
lysE
lysine exporter protein

Position: -44
Score: 5
Sequence: AATTTTCTTAAAATT
Locus tag: STACA0001_1640
Name: asd
Funciton: aspartate-semialdehyde dehydrogenase
Locus tag: STACA0001_1641
Name: dapA
Funciton: dihydrodipicolinate synthase
Locus tag: STACA0001_1642
Name: dapB
Funciton: dihydrodipicolinate reductase
Locus tag: STACA0001_1643
Name: dapD
Funciton: tetrahydrodipicolinate acetyltransferase
Locus tag: STACA0001_1644
Name: ykuR
Funciton: amidohydrolase subfamily
Locus tag: STACA0001_1645
Name: dapX
Funciton: alanine racemase 2
Locus tag: STACA0001_1646
Name: lysA
Funciton: diaminopimelate decarboxylase
asd
aspartate-semialdehyde dehydrogenase
dapA
dihydrodipicolinate synthase
dapB
dihydrodipicolinate reductase
dapD
tetrahydrodipicolinate acetyltransferase
ykuR
amidohydrolase subfamily
dapX
alanine racemase 2
lysA
diaminopimelate decarboxylase

Position: -154
Score: 4.7
Sequence: AATATTCAGAATTAT
Locus tag: STACA0001_1558
Name: ltaE
Funciton: low specificity L-threonine aldolase
ltaE
low specificity L-threonine aldolase

Position: -131
Score: 4.7
Sequence: AATATTTAAAAATTT
Position: -121
Score: 5.1
Sequence: AATTTTCTGAAATTT
Locus tag: STACA0001_1577
Name: katA
Funciton: catalase
katA
catalase

Position: -35
Score: 4.8
Sequence: ACTATTCTGAAAATT
Locus tag: STACA0001_1611
Name: tyrA
Funciton: prephenate dehydrogenase
tyrA
prephenate dehydrogenase

Position: -438
Score: 4.6
Sequence: AATAATTAGAAAAAT
Position: -429
Score: 4.4
Sequence: AAAAATCAGATAATT
Locus tag: STACA0001_1613
Name: trpE
Funciton: anthranilate synthase component I
Locus tag: STACA0001_1614
Name: trpG
Funciton: anthranilate synthase component II
Locus tag: STACA0001_1615
Name: trpD
Funciton: anthranilate phosphoribosyltransferase
Locus tag: STACA0001_1616
Name: trpC
Funciton: indole-3-glycerol phosphate synthase
Locus tag: STACA0001_1617
Name: trpF
Funciton: phosphoriborylanthranilate isomerase
Locus tag: STACA0001_1618
Name: trpB
Funciton: tryptophan synthase beta subunit
Locus tag: STACA0001_1619
Name: trpA
Funciton: tryptophan synthase alpha subunit
trpE
anthranilate synthase component I
trpG
anthranilate synthase component II
trpD
anthranilate phosphoribosyltransferase
trpC
indole-3-glycerol phosphate synthase
trpF
phosphoriborylanthranilate isomerase
trpB
tryptophan synthase beta subunit
trpA
tryptophan synthase alpha subunit

Position: -124
Score: 4.3
Sequence: AATTGACTGAATATT
Position: -115
Score: 4.5
Sequence: AATATTCATATTATT
Position: -98
Score: 4.8
Sequence: TATTTTTTGAAAATT
Locus tag: STACA0001_0301
Name: tppB
Funciton: di-tripepride ABC transporter
tppB
di-tripepride ABC transporter

Position: -33
Score: 4.7
Sequence: AATTTTCTGATTTTT
Locus tag: STACA0001_1570
Name: thrA
Funciton: aspartokinase III
thrA
aspartokinase III

Position: -133
Score: 5.1
Sequence: ATTATTCAGAAAATT
Locus tag: STACA0001_1450
Name: tcyP
Funciton: L-cystine uptake protein tcyP
tcyP
L-cystine uptake protein tcyP

Position: -219
Score: 4.3
Sequence: TATTTTCAAAAAACT
Position: -184
Score: 4.2
Sequence: AATGGTCTGAAAAAT
Locus tag: STACA0001_1791
Name: sodA
Funciton: superoxide dismutase SodA
sodA
superoxide dismutase SodA

Position: -29
Score: 4.8
Sequence: AATTTTCAGATATTT
Locus tag: STACA0001_1448
Name: SE2356
Funciton: 2-oxo-hepta-3-ene-1,7-dioate hydratase
SE2356
2-oxo-hepta-3-ene-1,7-dioate hydratase

Position: -178
Score: 4.7
Sequence: ATAATTCTGAATATT
Locus tag: STACA0001_1559
Name: SAS040
Funciton: hypothetical protein
Locus tag: STACA0001_1560
Name: SA1155
Funciton: putative cardiolipin synthetase
SAS040
hypothetical protein
SA1155
putative cardiolipin synthetase

Position: -33
Score: 4.4
Sequence: TAAATTCAAAATATT
Position: -24
Score: 5
Sequence: AATATTTTAAAAATT
Locus tag: STACA0001_0445
Name: SE0357
Funciton: hypothetical protein
Locus tag: STACA0001_0446
Name: SE0356
Funciton: hypothetical protein
SE0357
hypothetical protein
SE0356
hypothetical protein
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