Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Burkholderia sp. 383

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Burkholderia
Under regulation:
- Genes 20
- Operons 6
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -227
Score: 89.3
Sequence: CTACGGCCGTTCGTT...
Locus tag: Bcep18194_A4824
Name: cobG
Funciton: Cobalamin biosynthesis protein CobG
Locus tag: Bcep18194_A4823
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Bcep18194_A4822
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Bcep18194_A4821
Name: cbiGH
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase
cobG
Cobalamin biosynthesis protein CobG
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiGH
Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-3b C17-methyltransferase

Position: -174
Score: 45
Sequence: CCGCTTCAATACGCG...
Locus tag: Bcep18194_B0359
Name: bglu_2g19320
Funciton: hypothetical protein
Locus tag: Bcep18194_B0360
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
bglu_2g19320
hypothetical protein
cbtA
Predicted cobalt transporter CbtA

Position: -595
Score: 42.1
Sequence: ACACTCGCACGCGTT...
Locus tag: Bcep18194_A4805
Name: cobW
Funciton: CobW GTPase involved in cobalt insertion for B12 biosynthesis
Locus tag: Bcep18194_A4806
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Bcep18194_A4807
Name: chlI
Funciton: ChlI component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Bcep18194_A4808
Name: chlD
Funciton: ChlD component of cobalt chelatase involved in B12 biosynthesis
cobW
CobW GTPase involved in cobalt insertion for B12 biosynthesis
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
chlI
ChlI component of cobalt chelatase involved in B12 biosynthesis
chlD
ChlD component of cobalt chelatase involved in B12 biosynthesis

Position: -411
Score: 15.9
Sequence: CCTAAACTGGCGCCG...
Locus tag: Bcep18194_A5786
Name: btuC
Funciton: ABC-type cobalamin transport system, permease component
Locus tag: Bcep18194_A5785
Name: btuD
Funciton: ABC-type cobalamin transport system, ATPase components
Locus tag: Bcep18194_A5784
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Bcep18194_A5783
Name: cobS
Funciton: Cobalamin-5-phosphate synthase CobS
Locus tag: Bcep18194_A5782
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
btuC
ABC-type cobalamin transport system, permease component
btuD
ABC-type cobalamin transport system, ATPase components
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobS
Cobalamin-5-phosphate synthase CobS
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)

Position: -254
Score: 115.1
Sequence: ATTACCCTTGCGCGC...
Locus tag: Bcep18194_B1485
Name: btuB1
Funciton: Outer membrane vitamin B12 receptor BtuB
btuB1
Outer membrane vitamin B12 receptor BtuB

Position: -408
Score: 35.8
Sequence: TATCGTATGCGCCGC...
Locus tag: Bcep18194_A4802
Name: cysG
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Bcep18194_A4801
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: Bcep18194_A4800
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: Bcep18194_A4799
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
cysG
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
cbiG
Cobalamin biosynthesis protein CbiG
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cbiA
Cobyrinic acid A,C-diamide synthase
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD