Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Lactobacillus salivarius subsp. salivarius UCC118

Properties
Regulator type: Transcription factor
TF locus tag: LSL_0315
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes 14
- Operons 4
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 76 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -130
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LSL_1139
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -27
Score: 5.2
Sequence: AAAGACGAACAAT
Locus tag: LSL_0663
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: LSL_0664
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: LSL_0665
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: LSL_0666
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: LSL_0667
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: LSL_0668
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: LSL_0669
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: LSL_0670
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: LSL_0671
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)

Position: -68
Score: 4.1
Sequence: AAATTCGAATTTT
Locus tag: LSL_0515
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: LSL_0516
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: LSL_0517
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purB
Adenylosuccinate lyase (EC 4.3.2.2)

Position: -116
Score: 5.4
Sequence: AAAAACGAACTTT
Locus tag: LSL_0315
Name: purR
Funciton: Purine metabolism transcriptional regulator PurR, PurR family
purR
Purine metabolism transcriptional regulator PurR, PurR family
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD