Regulon of PurR in Lactobacillus sakei subsp. sakei 23K

Properties
Regulator type:	Transcription factor
TF locus tag:	LSA1651
Regulator family:	PurR
Regulation mode:	repressor
Biological process:	Purine metabolism
Effector:	5-phosphoribosyl 1-pyrophosphate
Regulog:	PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes	16
- Operons	6
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 76 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By TF family - PurR
By effector - 5-phosphoribosyl 1-pyrophosphate
By pathway - Purine metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -110 Score: 4.9 Sequence: ATAAACGAACTTT Position: -58 Score: 5.6 Sequence: AAAAACGAACAAT Locus tag: LSA0655 Name: purC Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) Locus tag: LSA0656 Name: purS Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3) Locus tag: LSA0657 Name: purQ Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) Locus tag: LSA0658 Name: purL Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) Locus tag: LSA0659 Name: purF Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14) Locus tag: LSA0660 Name: purM Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) Locus tag: LSA0661 Name: purN Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) Locus tag: LSA0662 Name: purH Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) Locus tag: LSA0663 Name: purD Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
	LSA0655	purC	Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
	LSA0656	purS	Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
	LSA0657	purQ	Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
	LSA0658	purL	Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
	LSA0659	purF	Amidophosphoribosyltransferase (EC 2.4.2.14)
	LSA0660	purM	Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
	LSA0661	purN	Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
	LSA0662	purH	IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
	LSA0663	purD	Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Position: -112 Score: 4.3 Sequence: TAACACGTACAAT Locus tag: LSA0652 Name: purE Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) Locus tag: LSA0653 Name: purK Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) Locus tag: LSA0654 Name: purB Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
	LSA0652	purE	Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
	LSA0653	purK	Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
	LSA0654	purB	Adenylosuccinate lyase (EC 4.3.2.2)
Position: -56 Score: 4.9 Sequence: TAATACGAACATT Locus tag: LSA0276 Name: guaB Funciton: Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
	LSA0276	guaB	Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
Position: -101 Score: 5.4 Sequence: AAACACGAACTAT Locus tag: LSA0087 Name: pbuO Funciton: Guanine/hypoxanthine permease
	LSA0087	pbuO	Guanine/hypoxanthine permease
Position: -24 Score: 4.2 Sequence: AATCACGAATATT Locus tag: LSA1648 Name: glmU Funciton: N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
	LSA1648	glmU	N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
Position: -120 Score: 5.6 Sequence: AAAAACGAACAAT Locus tag: LSA1651 Name: purR Funciton: Purine metabolism transcriptional regulator PurR, PurR family
	LSA1651	purR	Purine metabolism transcriptional regulator PurR, PurR family

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of PurR in Lactobacillus sakei subsp. sakei 23K

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --