Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Lactobacillus rhamnosus GG

Properties
Regulator type: Transcription factor
TF locus tag: LGG_02564
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes 16
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 76 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -194
Score: 5.3
Sequence: AAAGACGAACATT
Locus tag: LGG_00249
Name: guaB
Funciton: Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
LGG_00249
guaB
Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
Position: -134
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LGG_00874
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
LGG_00874
guaC
GMP reductase (EC 1.7.1.7)
Position: -108
Score: 5.5
Sequence: AAATACGAACATT
Position: -96
Score: 4.3
Sequence: TAAAACGAATAAT
Locus tag: LGG_01814
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: LGG_01813
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: LGG_01812
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: LGG_01811
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: LGG_01810
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: LGG_01809
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: LGG_01808
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: LGG_01807
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: LGG_01806
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: LGG_01805
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: LGG_01804
Name: LGG_02640
Funciton: Hypothetical protein
Locus tag: LGG_01803
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
LGG_01814
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
LGG_01813
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
LGG_01812
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
LGG_01811
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
LGG_01810
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
LGG_01809
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
LGG_01808
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
LGG_01807
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
LGG_01806
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
LGG_01805
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
LGG_01804
LGG_02640
Hypothetical protein
LGG_01803
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Position: -105
Score: 5.6
Sequence: AAACACGAACATT
Locus tag: LGG_00168
Name: pbuO
Funciton: Guanine/hypoxanthine permease
LGG_00168
pbuO
Guanine/hypoxanthine permease
Position: -126
Score: 4.8
Sequence: AAATGCGAACGTT
Locus tag: LGG_02564
Name: purR
Funciton: Purine metabolism transcriptional regulator PurR, PurR family
LGG_02564
purR
Purine metabolism transcriptional regulator PurR, PurR family
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