Regulon of PurR in Lactobacillus reuteri JCM 1112

Properties
Regulator type:	Transcription factor
TF locus tag:	LAR_0210
Regulator family:	PurR
Regulation mode:	repressor
Biological process:	Purine metabolism
Effector:	5-phosphoribosyl 1-pyrophosphate
Regulog:	PurR - Lactobacillaceae
Statistics of regulated genes:
- Genes	15
- Operons	3
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 76 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By TF family - PurR
By effector - 5-phosphoribosyl 1-pyrophosphate
By pathway - Purine metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -153 Score: 5.6 Sequence: AAACACGAACAAT Locus tag: LAR_0131 Name: purC Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) Locus tag: LAR_0132 Name: purS Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3) Locus tag: LAR_0133 Name: purQ Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) Locus tag: LAR_0134 Name: purL Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) Locus tag: LAR_0135 Name: purF Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14) Locus tag: LAR_0136 Name: purM Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) Locus tag: LAR_0137 Name: purN Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) Locus tag: LAR_0138 Name: purH Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) Locus tag: LAR_0139 Name: purD Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
	LAR_0131	purC	Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
	LAR_0132	purS	Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
	LAR_0133	purQ	Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
	LAR_0134	purL	Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
	LAR_0135	purF	Amidophosphoribosyltransferase (EC 2.4.2.14)
	LAR_0136	purM	Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
	LAR_0137	purN	Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
	LAR_0138	purH	IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
	LAR_0139	purD	Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Position: -102 Score: 4.9 Sequence: ATACACGAACTAT Locus tag: LAR_0128 Name: purE Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) Locus tag: LAR_0129 Name: purK Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) Locus tag: LAR_0130 Name: purB Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
	LAR_0128	purE	Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
	LAR_0129	purK	Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
	LAR_0130	purB	Adenylosuccinate lyase (EC 4.3.2.2)
Position: -64 Score: 5.2 Sequence: AAATCCGAACATT Locus tag: LAR_0210 Name: purR Funciton: Purine metabolism transcriptional regulator PurR, PurR family Locus tag: LAR_0211 Name: glmU Funciton: N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157) Locus tag: LAR_0212 Name: prsA Funciton: Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
	LAR_0210	purR	Purine metabolism transcriptional regulator PurR, PurR family
	LAR_0211	glmU	N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)
	LAR_0212	prsA	Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)

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