Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of SAM in Geobacillus kaustophilus HTA426

Properties
Regulator type: RNA regulatory element
Name: SAM
RFAM: RF00162
Regulation mode:
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: SAM - Bacillales
Under regulation:
- Genes 24
- Operons 9
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -179
Score: 84.4
Sequence: TCTTATCAAGAGCAG...
Locus tag: GK0953
Name: mtnW
Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase
Locus tag: GK0954
Name: mtnX
Funciton: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
Locus tag: GK0955
Name: mtnB
Funciton: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
Locus tag: GK0956
Name: mtnD
Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
mtnW
2,3-diketo-5-methylthiopentyl-1-phosphate enolase
mtnX
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
mtnB
Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
mtnD
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)

Position: -311
Score: 87.5
Sequence: TCTTATCAAGAGAAG...
Locus tag: GK0866
Name: metI
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: GK0867
Name: metC
Funciton: Cystathionine beta-lyase (EC 4.4.1.8)
metI
Cystathionine gamma-synthase (EC 2.5.1.48)
metC
Cystathionine beta-lyase (EC 4.4.1.8)

Position: -175
Score: 86
Sequence: ATTCTTATCAAGAGA...
Locus tag: GK0717
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
Locus tag: GK0716
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Position: -231
Score: 43.7
Sequence: ACGTTGCTCGGGAGT...
Locus tag: GK0416
Name: cysH
Funciton: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Locus tag: GK0415
Name: sat
Funciton: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
Locus tag: GK0414
Name: cysC
Funciton: Adenylylsulfate kinase (EC 2.7.1.25)
Locus tag: GK0413
Name: cysG
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: GK0412
Name: sirB
Funciton: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
cysH
Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
sat
Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
cysC
Adenylylsulfate kinase (EC 2.7.1.25)
cysG
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
sirB
Sirohydrochlorin ferrochelatase (EC 4.99.1.4)

Position: -198
Score: 90.2
Sequence: GCTCTTATCAAGAGA...
Locus tag: GK2999
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: GK2998
Name: metP
Funciton: Methionine ABC transporter permease protein
Locus tag: GK2997
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
metN
Methionine ABC transporter ATP-binding protein
metP
Methionine ABC transporter permease protein
metQ
Methionine ABC transporter substrate-binding protein

Position: -526
Score: 69.1
Sequence: TCTTATCAAGAGTGG...
Locus tag: GK1362
Name: ywbC
Funciton: Lactoylglutathione lyase and related lyases
ywbC
Lactoylglutathione lyase and related lyases

Position: -231
Score: 43.7
Sequence: ACGTTGCTCGGGAGT...
Locus tag: GK0416
Name: cysH
Funciton: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
cysH
Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)

Position: -245
Score: 72
Sequence: ACTCTTATCCCGAGC...
Locus tag: GK2849
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)

Position: -307
Score: 61.4
Sequence: CTTATCAAGAGTTGG...
Locus tag: GK0950
Name: mtnK
Funciton: 5-methylthioribose kinase (EC 2.7.1.100)
Locus tag: GK0949
Name: mtnA
Funciton: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
Locus tag: GK0948
Name: mtrB
Funciton: Methythioribose ABC transport system, substrate-binding protein
Locus tag: GK0947
Name: mtrA
Funciton: Methythioribose ABC transport system, ATP-binding protein
Locus tag: GK0946
Name: mtrC
Funciton: Methythioribose ABC transport system, permease protein
mtnK
5-methylthioribose kinase (EC 2.7.1.100)
mtnA
Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
mtrB
Methythioribose ABC transport system, substrate-binding protein
mtrA
Methythioribose ABC transport system, ATP-binding protein
mtrC
Methythioribose ABC transport system, permease protein
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