Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of SAM in Bacillus licheniformis DSM 13

Properties
Regulator type: RNA regulatory element
Name: SAM
RFAM: RF00162
Regulation mode:
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: SAM - Bacillales
Under regulation:
- Genes 25
- Operons 10
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -572
Score: 85.9
Sequence: ACTTATCAAGAGCGG...
Locus tag: BLi01778
Name: cysH
Funciton: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Locus tag: BLi01779
Name: cysP
Funciton: Sulfate permease, Pit-type
Locus tag: BLi01780
Name: sat
Funciton: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
Locus tag: BLi01781
Name: cysC
Funciton: Adenylylsulfate kinase (EC 2.7.1.25)
Locus tag: BLi01782
Name: cysG
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: BLi01783
Name: sirB
Funciton: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Locus tag: BLi01784
Name: sirC
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
cysH
Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
cysP
Sulfate permease, Pit-type
sat
Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
cysC
Adenylylsulfate kinase (EC 2.7.1.25)
cysG
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
sirB
Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
sirC
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)

Position: -229
Score: 76.9
Sequence: TCTCTTATCGAGAGT...
Locus tag: BLi01512
Name: mtnK
Funciton: 5-methylthioribose kinase (EC 2.7.1.100)
Locus tag: BLi01511
Name: mtnA
Funciton: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
mtnK
5-methylthioribose kinase (EC 2.7.1.100)
mtnA
Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)

Position: -156
Score: 84.1
Sequence: TCTTATCAAGAGCAG...
Locus tag: BLi01515
Name: mtnW
Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase
Locus tag: BLi01516
Name: mtnX
Funciton: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
Locus tag: BLi01517
Name: mtnD
Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
mtnW
2,3-diketo-5-methylthiopentyl-1-phosphate enolase
mtnX
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
mtnD
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)

Position: -471
Score: 71.6
Sequence: ACTCTTATCCCGAGC...
Locus tag: BLi03196
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)

Position: -213
Score: 72
Sequence: TCTTATTCAGAGAGG...
Locus tag: BLi00972
Name: metN3
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: BLi00973
Name: metP3
Funciton: Methionine ABC transporter permease protein
Locus tag: BLi00974
Name: metQ3
Funciton: Methionine ABC transporter substrate-binding protein
metN3
Methionine ABC transporter ATP-binding protein
metP3
Methionine ABC transporter permease protein
metQ3
Methionine ABC transporter substrate-binding protein

Position: -182
Score: 94.1
Sequence: CCTTATCAAGAGTGG...
Locus tag: BLi04187
Name: metE2
Funciton: Putative methionine synthase II (cobalamin-independent)
metE2
Putative methionine synthase II (cobalamin-independent)

Position: -165
Score: 85.2
Sequence: CAGCTTATAAAGAGA...
Locus tag: BLi03178
Name: metQ1
Funciton: Methionine ABC transporter substrate-binding protein
metQ1
Methionine ABC transporter substrate-binding protein

Position: -141
Score: 92.8
Sequence: TCTTATCACGAGAGG...
Locus tag: BLi01289
Name: metI
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: BLi01290
Name: metC
Funciton: Cystathionine beta-lyase (EC 4.4.1.8)
metI
Cystathionine gamma-synthase (EC 2.5.1.48)
metC
Cystathionine beta-lyase (EC 4.4.1.8)

Position: -225
Score: 93.7
Sequence: TCTCTTATCCAGAGA...
Locus tag: BLi03457
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: BLi03456
Name: metP
Funciton: Methionine ABC transporter permease protein
Locus tag: BLi03455
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
metN
Methionine ABC transporter ATP-binding protein
metP
Methionine ABC transporter permease protein
metQ
Methionine ABC transporter substrate-binding protein

Position: -193
Score: 99.2
Sequence: GTTCTTATCAAGAGA...
Locus tag: BLi01193
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
Locus tag: BLi01192
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD