Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of SAM in Bacillus pumilus SAFR-032

Properties
Regulator type: RNA regulatory element
Name: SAM
RFAM: RF00162
Regulation mode:
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: SAM - Bacillales
Under regulation:
- Genes 25
- Operons 9
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -173
Score: 86.4
Sequence: TCTTATCAAGAGTAG...
Locus tag: BPUM_1252
Name: mtnW
Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase
Locus tag: BPUM_1253
Name: mtnX
Funciton: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
Locus tag: BPUM_1254
Name: mtnB
Funciton: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
Locus tag: BPUM_1255
Name: mtnD
Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
mtnW
2,3-diketo-5-methylthiopentyl-1-phosphate enolase
mtnX
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
mtnB
Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
mtnD
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)

Position: -239
Score: 62
Sequence: TCTCTTATCGAGAGT...
Locus tag: BPUM_1250
Name: mtnK
Funciton: 5-methylthioribose kinase (EC 2.7.1.100)
Locus tag: BPUM_1249
Name: mtnA
Funciton: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
mtnK
5-methylthioribose kinase (EC 2.7.1.100)
mtnA
Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)

Position: -280
Score: 94.7
Sequence: TCTCTTATCAAGAGA...
Locus tag: BPUM_3498
Name: mtrB
Funciton: Methythioribose ABC transport system, substrate-binding protein
Locus tag: BPUM_3497
Name: mtrA
Funciton: Methythioribose ABC transport system, ATP-binding protein
Locus tag: BPUM_3496
Name: mtrC
Funciton: Methythioribose ABC transport system, permease protein
mtrB
Methythioribose ABC transport system, substrate-binding protein
mtrA
Methythioribose ABC transport system, ATP-binding protein
mtrC
Methythioribose ABC transport system, permease protein

Position: -330
Score: 72.2
Sequence: ACTCTTATCCCGAGT...
Locus tag: BPUM_2686
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)

Position: -264
Score: 86.4
Sequence: TCTCTTATTAAGAGA...
Locus tag: BPUM_2932
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: BPUM_2931
Name: metP
Funciton: Methionine ABC transporter permease protein
Locus tag: BPUM_2930
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
metN
Methionine ABC transporter ATP-binding protein
metP
Methionine ABC transporter permease protein
metQ
Methionine ABC transporter substrate-binding protein

Position: -200
Score: 92.6
Sequence: TCTTATCGTGAGAGG...
Locus tag: BPUM_1119
Name: metI
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: BPUM_1120
Name: metC
Funciton: Cystathionine beta-lyase (EC 4.4.1.8)
metI
Cystathionine gamma-synthase (EC 2.5.1.48)
metC
Cystathionine beta-lyase (EC 4.4.1.8)

Position: -198
Score: 96.7
Sequence: TTTCTTATCAAGAGA...
Locus tag: BPUM_1027
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
Locus tag: BPUM_1026
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Position: -199
Score: 79.4
Sequence: CCTTATTAAGAGTGG...
Locus tag: BPUM_3562
Name: metE2
Funciton: Putative methionine synthase II (cobalamin-independent)
metE2
Putative methionine synthase II (cobalamin-independent)

Position: -336
Score: 90.1
Sequence: ACTTATCCAGAGAGG...
Locus tag: BPUM_1456
Name: cysH
Funciton: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Locus tag: BPUM_1457
Name: cysP
Funciton: Sulfate permease, Pit-type
Locus tag: BPUM_1458
Name: sat
Funciton: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
Locus tag: BPUM_1459
Name: cysC
Funciton: Adenylylsulfate kinase (EC 2.7.1.25)
Locus tag: BPUM_1460
Name: cysG
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: BPUM_1461
Name: sirB
Funciton: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Locus tag: BPUM_1462
Name: sirC
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
cysH
Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
cysP
Sulfate permease, Pit-type
sat
Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
cysC
Adenylylsulfate kinase (EC 2.7.1.25)
cysG
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
sirB
Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
sirC
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD