Regulon of FruR in Escherichia coli str. K-12 substr. MG1655
| Regulator type: | Transcription factor |
| TF locus tag: | b0080 |
| Regulator family: | LacI |
| Regulation mode: | activator (repressor) |
| Biological process: | Central carbohydrate metabolism |
| Effector: | Fructose-1-phosphate; Fructose-1,6-diphosphate |
| Regulog: | FruR - Enterobacteriales |
| Statistics of regulated genes: | |
| - Genes | 54 |
| - Operons | 24 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Enterobacteriales
- By trascription factor - FruR
- By TF family - LacI
- By effector - Fructose-1-phosphate
- By effector - Fructose-1,6-diphosphate
- By pathway - Central carbohydrate metabolism
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -113
Score: 4.4 Sequence: ACTGAAACGTTTTTGC
Locus tag: b1851
Name: edd Funciton: Phosphogluconate dehydratase (EC 4.2.1.12)
Locus tag: b1850
Name: eda Funciton: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) |
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edd
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Phosphogluconate dehydratase (EC 4.2.1.12)
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eda
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2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)
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Position: -246
Score: 4.6 Sequence: GCTGAATCGCTTAACC
Locus tag: b1136
Name: icdA Funciton: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) |
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icdA
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Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
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Position: -35
Score: 5.4 Sequence: GCTGAATCGTTTCAAT
Locus tag: b2169
Name: fruB Funciton: Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69)
Locus tag: b2168
Name: fruK Funciton: 1-phosphofructokinase (EC 2.7.1.56)
Locus tag: b2167
Name: fruA Funciton: PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) |
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fruB
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Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69)
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fruK
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1-phosphofructokinase (EC 2.7.1.56)
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fruA
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PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69)
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Position: -121
Score: 5.1 Sequence: CCTGAATCAATTCAGC
Locus tag: b3916
Name: pfkA Funciton: 6-phosphofructokinase (EC 2.7.1.11) |
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pfkA
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6-phosphofructokinase (EC 2.7.1.11)
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Position: -286
Score: 4.3 Sequence: GGTGAATCGATACTTT
Locus tag: b3403
Name: pckA Funciton: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) |
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pckA
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Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)
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Position: -221
Score: 4.9 Sequence: CTTGAATGGTTTCAGC
Locus tag: b1676
Name: pykF Funciton: Pyruvate kinase (EC 2.7.1.40) |
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pykF
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Pyruvate kinase (EC 2.7.1.40)
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Position: -102
Score: 4.6 Sequence: GCTTGAACGATTCACC
Locus tag: b1702
Name: ppsA Funciton: Phosphoenolpyruvate synthase (EC 2.7.9.2) |
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ppsA
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Phosphoenolpyruvate synthase (EC 2.7.9.2)
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Position: -134
Score: 4.9 Sequence: GCTGAAACGATAAAGT
Locus tag: b2388
Name: glk Funciton: Glucokinase (EC 2.7.1.2) |
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glk
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Glucokinase (EC 2.7.1.2)
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Position: -47
Score: 4.6 Sequence: GCTGAATCGTTAAGGT
Locus tag: b3365
Name: nirB Funciton: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
Locus tag: b3366
Name: nirD Funciton: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
Locus tag: b3367
Name: nirC Funciton: FNT family, nitrite transport protein
Locus tag: b3368
Name: cysG Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) |
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nirB
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Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
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nirD
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Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
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nirC
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FNT family, nitrite transport protein
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cysG
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Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
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Position: -82
Score: 4.5 Sequence: TCTGAATCGATTCGAT
Locus tag: b1817
Name: manX Funciton: PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69)
Locus tag: b1818
Name: manY Funciton: PTS system, mannose-specific IIC component (EC 2.7.1.69)
Locus tag: b1819
Name: manZ Funciton: PTS system, mannose-specific IID component (EC 2.7.1.69) |
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manX
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PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69)
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manY
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PTS system, mannose-specific IIC component (EC 2.7.1.69)
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manZ
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PTS system, mannose-specific IID component (EC 2.7.1.69)
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Position: -137
Score: 5.4 Sequence: GCTGAAGCGTTTCAGT
Locus tag: b2927
Name: epd Funciton: D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72)
Locus tag: b2926
Name: pgk Funciton: Phosphoglycerate kinase (EC 2.7.2.3) |
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epd
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D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72)
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pgk
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Phosphoglycerate kinase (EC 2.7.2.3)
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Position: -219
Score: 4.7 Sequence: GCTGAATCGATTTTAT
Locus tag: b2415
Name: ptsH Funciton: PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase
Locus tag: b2416
Name: ptsI Funciton: Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
Locus tag: b2417
Name: crr Funciton: PTS system, glucose-specific IIA component (EC 2.7.1.69) |
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ptsH
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PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase
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ptsI
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Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
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crr
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PTS system, glucose-specific IIA component (EC 2.7.1.69)
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Position: -161
Score: 4.6 Sequence: GTTGAACCGATTAAGC
Locus tag: b3919
Name: tpiA Funciton: Triosephosphate isomerase (EC 5.3.1.1) |
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tpiA
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Triosephosphate isomerase (EC 5.3.1.1)
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Position: -283
Score: 3.6 Sequence: ACGGACACGATTCAAC
Locus tag: b2288
Name: nuoA Funciton: NADH dehydrogenase I chain A
Locus tag: b2287
Name: nuoB Funciton: NADH dehydrogenase I chain B
Locus tag: b2286
Name: nuoD Funciton: NADH dehydrogenase I chain C,D
Locus tag: b2285
Name: nuoE Funciton: NADH dehydrogenase I chain E
Locus tag: b2284
Name: nuoF Funciton: NADH dehydrogenase I chain F
Locus tag: b2283
Name: nuoG Funciton: NADH dehydrogenase I chain G
Locus tag: b2282
Name: nuoH Funciton: NADH dehydrogenase I chain H
Locus tag: b2281
Name: nuoI Funciton: NADH dehydrogenase I chain I
Locus tag: b2280
Name: nuoJ Funciton: NADH dehydrogenase I chain J
Locus tag: b2279
Name: nuoK Funciton: NADH dehydrogenase I chain K
Locus tag: b2278
Name: nuoL Funciton: NADH dehydrogenase I chain L
Locus tag: b2277
Name: nuoM Funciton: NADH dehydrogenase I chain M
Locus tag: b2276
Name: nuoN Funciton: NADH dehydrogenase I chain N |
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nuoA
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NADH dehydrogenase I chain A
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nuoB
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NADH dehydrogenase I chain B
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nuoD
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NADH dehydrogenase I chain C,D
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nuoE
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NADH dehydrogenase I chain E
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nuoF
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NADH dehydrogenase I chain F
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nuoG
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NADH dehydrogenase I chain G
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nuoH
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NADH dehydrogenase I chain H
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nuoI
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NADH dehydrogenase I chain I
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nuoJ
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NADH dehydrogenase I chain J
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nuoK
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NADH dehydrogenase I chain K
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nuoL
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NADH dehydrogenase I chain L
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nuoM
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NADH dehydrogenase I chain M
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nuoN
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NADH dehydrogenase I chain N
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Position: -123
Score: 4 Sequence: AGTTAACCGATTCAGT
Locus tag: b3599
Name: mtlA Funciton: mannitol-specific PTS system, IIABC components |
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mtlA
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mannitol-specific PTS system, IIABC components
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Position: -220
Score: 4.3 Sequence: GCTGAAGCGAGACACC
Locus tag: b3357
Name: crp Funciton: Catabolite gene activator (cAMP receptor protein), CRP family |
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crp
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Catabolite gene activator (cAMP receptor protein), CRP family
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Position: -305
Score: 4.2 Sequence: ATTGAACCGATTCACT
Locus tag: b0112
Name: aroP Funciton: Aromatic amino acid transport protein AroP |
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aroP
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Aromatic amino acid transport protein AroP
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Position: -146
Score: 4.4 Sequence: GCTGAAGCGATTTCGC
Locus tag: b3956
Name: ppc Funciton: Phosphoenolpyruvate carboxylase (EC 4.1.1.31) |
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ppc
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Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
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Position: -250
Score: 4.6 Sequence: CGTTAAGCGATTCAGC
Locus tag: b4014
Name: aceB Funciton: Malate synthase (EC 2.3.3.9)
Locus tag: b4015
Name: aceA Funciton: Isocitrate lyase (EC 4.1.3.1)
Locus tag: b4016
Name: aceK Funciton: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-) |
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aceB
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Malate synthase (EC 2.3.3.9)
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aceA
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Isocitrate lyase (EC 4.1.3.1)
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aceK
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Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)
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Position: -264
Score: 4.6 Sequence: GCTGAAAGGTGTCAGC
Locus tag: b1241
Name: adhE Funciton: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
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adhE
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Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
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Position: -90
Score: 4.3 Sequence: GCTGGCGCGATTCACC
Locus tag: b4232
Name: fbp Funciton: Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) |
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fbp
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Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11)
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Position: -251
Score: 4.2 Sequence: AGTGAATCGGTTCAAT
Locus tag: b0113
Name: pdhR Funciton: Transcriptional repressor for pyruvate dehydrogenase, GntR family
Locus tag: b0114
Name: aceE Funciton: Pyruvate dehydrogenase E1 component (EC 1.2.4.1)
Locus tag: b0115
Name: aceF Funciton: Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) |
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pdhR
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Transcriptional repressor for pyruvate dehydrogenase, GntR family
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aceE
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Pyruvate dehydrogenase E1 component (EC 1.2.4.1)
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aceF
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Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)
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Position: -87
Score: 3.7 Sequence: ATTGACACGATTCCGC
Locus tag: b1779
Name: gapA Funciton: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Locus tag: b1780
Name: yeaD Funciton: Aldose 1-epimerase family protein YeaD |
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gapA
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NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
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yeaD
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Aldose 1-epimerase family protein YeaD
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Position: -64
Score: 4.1 Sequence: ATTTTATCGATTCAGC
Locus tag: b3612
Name: gpmM Funciton: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)
Locus tag: b3613
Name: yibP Funciton: murein hydrolase
Locus tag: b3614
Name: yibQ Funciton: protein of unknown function DUF610 |
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gpmM
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2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)
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yibP
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murein hydrolase
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yibQ
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protein of unknown function DUF610
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |