Regulon of FruR in Enterobacter sp. 638
| Regulator type: | Transcription factor |
| TF locus tag: | Ent638_0626 |
| Regulator family: | LacI |
| Regulation mode: | activator (repressor) |
| Biological process: | Central carbohydrate metabolism |
| Effector: | Fructose-1-phosphate; Fructose-1,6-diphosphate |
| Regulog: | FruR - Enterobacteriales |
| Statistics of regulated genes: | |
| - Genes | 55 |
| - Operons | 22 |
| Visualization: | |
|
Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Enterobacteriales
- By trascription factor - FruR
- By TF family - LacI
- By effector - Fructose-1-phosphate
- By effector - Fructose-1,6-diphosphate
- By pathway - Central carbohydrate metabolism
| Locus Tag | Name | Function | |
|---|---|---|---|
|
Position: -36
Score: 4.8 Sequence: GCTGAAACGATTCAAG
Locus tag: Ent638_2763
Name: fruB Funciton: Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69)
Locus tag: Ent638_2762
Name: fruK Funciton: 1-phosphofructokinase (EC 2.7.1.56)
Locus tag: Ent638_2761
Name: fruA Funciton: PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69) |
|||
|
fruB
|
Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69)
|
||
|
fruK
|
1-phosphofructokinase (EC 2.7.1.56)
|
||
|
fruA
|
PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69)
|
||
|
Position: -170
Score: 5.1 Sequence: CCTGAATCAATTCAGC
Locus tag: Ent638_4056
Name: pfkA Funciton: 6-phosphofructokinase (EC 2.7.1.11) |
|||
|
pfkA
|
6-phosphofructokinase (EC 2.7.1.11)
|
||
|
Position: -221
Score: 5 Sequence: GGTGAATGGTTTCAGC
Locus tag: Ent638_1768
Name: pykF Funciton: Pyruvate kinase (EC 2.7.1.40) |
|||
|
pykF
|
Pyruvate kinase (EC 2.7.1.40)
|
||
|
Position: -103
Score: 4.4 Sequence: GCTTACACGATTCACC
Locus tag: Ent638_1745
Name: ppsA Funciton: Phosphoenolpyruvate synthase (EC 2.7.9.2) |
|||
|
ppsA
|
Phosphoenolpyruvate synthase (EC 2.7.9.2)
|
||
|
Position: -134
Score: 4.5 Sequence: GCTGAAACGGTAAAGT
Locus tag: Ent638_2921
Name: glk Funciton: Glucokinase (EC 2.7.1.2) |
|||
|
glk
|
Glucokinase (EC 2.7.1.2)
|
||
|
Position: -47
Score: 4.6 Sequence: GCTGAATCGTTAAGGT
Locus tag: Ent638_3793
Name: nirB Funciton: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
Locus tag: Ent638_3794
Name: nirD Funciton: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
Locus tag: Ent638_3795
Name: nirC Funciton: FNT family, nitrite transport protein
Locus tag: Ent638_3796
Name: cysG Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) |
|||
|
nirB
|
Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
|
||
|
nirD
|
Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
|
||
|
nirC
|
FNT family, nitrite transport protein
|
||
|
cysG
|
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
|
||
|
Position: -82
Score: 4.7 Sequence: TCTGAATCGATTCGGT
Locus tag: Ent638_2386
Name: manX Funciton: PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69)
Locus tag: Ent638_2387
Name: manY Funciton: PTS system, mannose-specific IIC component (EC 2.7.1.69)
Locus tag: Ent638_2388
Name: manZ Funciton: PTS system, mannose-specific IID component (EC 2.7.1.69) |
|||
|
manX
|
PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69)
|
||
|
manY
|
PTS system, mannose-specific IIC component (EC 2.7.1.69)
|
||
|
manZ
|
PTS system, mannose-specific IID component (EC 2.7.1.69)
|
||
|
Position: -139
Score: 5.4 Sequence: GCTGAAGCGTTTCAGT
Locus tag: Ent638_3340
Name: epd Funciton: D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72)
Locus tag: Ent638_3339
Name: pgk Funciton: Phosphoglycerate kinase (EC 2.7.2.3)
Locus tag: Ent638_3338
Name: fbaA Funciton: Fructose-bisphosphate aldolase class II (EC 4.1.2.13) |
|||
|
epd
|
D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72)
|
||
|
pgk
|
Phosphoglycerate kinase (EC 2.7.2.3)
|
||
|
fbaA
|
Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
|
||
|
Position: -154
Score: 4.7 Sequence: GCTGAATCGATTTTAT
Locus tag: Ent638_2943
Name: ptsH Funciton: PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase
Locus tag: Ent638_2944
Name: ptsI Funciton: Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
Locus tag: Ent638_2945
Name: crr Funciton: PTS system, glucose-specific IIA component (EC 2.7.1.69) |
|||
|
ptsH
|
PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase
|
||
|
ptsI
|
Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
|
||
|
crr
|
PTS system, glucose-specific IIA component (EC 2.7.1.69)
|
||
|
Position: -283
Score: 3.6 Sequence: ACGGACACGATTCAAC
Locus tag: Ent638_2832
Name: nuoA Funciton: NADH dehydrogenase I chain A
Locus tag: Ent638_2831
Name: nuoB Funciton: NADH dehydrogenase I chain B
Locus tag: Ent638_2830
Name: nuoD Funciton: NADH dehydrogenase I chain C,D
Locus tag: Ent638_2829
Name: nuoE Funciton: NADH dehydrogenase I chain E
Locus tag: Ent638_2828
Name: nuoF Funciton: NADH dehydrogenase I chain F
Locus tag: Ent638_2827
Name: nuoG Funciton: NADH dehydrogenase I chain G
Locus tag: Ent638_2826
Name: nuoH Funciton: NADH dehydrogenase I chain H
Locus tag: Ent638_2825
Name: nuoI Funciton: NADH dehydrogenase I chain I
Locus tag: Ent638_2824
Name: nuoJ Funciton: NADH dehydrogenase I chain J
Locus tag: Ent638_2823
Name: nuoK Funciton: NADH dehydrogenase I chain K
Locus tag: Ent638_2822
Name: nuoL Funciton: NADH dehydrogenase I chain L
Locus tag: Ent638_2821
Name: nuoM Funciton: NADH dehydrogenase I chain M
Locus tag: Ent638_2820
Name: nuoN Funciton: NADH dehydrogenase I chain N |
|||
|
nuoA
|
NADH dehydrogenase I chain A
|
||
|
nuoB
|
NADH dehydrogenase I chain B
|
||
|
nuoD
|
NADH dehydrogenase I chain C,D
|
||
|
nuoE
|
NADH dehydrogenase I chain E
|
||
|
nuoF
|
NADH dehydrogenase I chain F
|
||
|
nuoG
|
NADH dehydrogenase I chain G
|
||
|
nuoH
|
NADH dehydrogenase I chain H
|
||
|
nuoI
|
NADH dehydrogenase I chain I
|
||
|
nuoJ
|
NADH dehydrogenase I chain J
|
||
|
nuoK
|
NADH dehydrogenase I chain K
|
||
|
nuoL
|
NADH dehydrogenase I chain L
|
||
|
nuoM
|
NADH dehydrogenase I chain M
|
||
|
nuoN
|
NADH dehydrogenase I chain N
|
||
|
Position: -122
Score: 3.7 Sequence: AGTTGAACGATTCGGT
Locus tag: Ent638_0136
Name: mtlA Funciton: mannitol-specific PTS system, IIABC components
Locus tag: Ent638_0135
Name: mtlD Funciton: mannitol-1-phosphate 5-dehydrogenase
Locus tag: Ent638_0134
Name: mtlR Funciton: Mannitol operon repressor |
|||
|
mtlA
|
mannitol-specific PTS system, IIABC components
|
||
|
mtlD
|
mannitol-1-phosphate 5-dehydrogenase
|
||
|
mtlR
|
Mannitol operon repressor
|
||
|
Position: -228
Score: 4.3 Sequence: GCTGAAGCGAGACACC
Locus tag: Ent638_3784
Name: crp Funciton: Catabolite gene activator (cAMP receptor protein), CRP family |
|||
|
crp
|
Catabolite gene activator (cAMP receptor protein), CRP family
|
||
|
Position: -304
Score: 4.4 Sequence: TCTGAACCGATTCACC
Locus tag: Ent638_0658
Name: aroP Funciton: Aromatic amino acid transport protein AroP |
|||
|
aroP
|
Aromatic amino acid transport protein AroP
|
||
|
Position: -126
Score: 4.1 Sequence: GCTGAACCGTTTTCGC
Locus tag: Ent638_4030
Name: ppc Funciton: Phosphoenolpyruvate carboxylase (EC 4.1.1.31) |
|||
|
ppc
|
Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
|
||
|
Position: -252
Score: 4.8 Sequence: CCTAAAGCGTTTCAGC
Locus tag: Ent638_0218
Name: aceB Funciton: Malate synthase (EC 2.3.3.9)
Locus tag: Ent638_0219
Name: aceA Funciton: Isocitrate lyase (EC 4.1.3.1)
Locus tag: Ent638_0220
Name: aceK Funciton: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-) |
|||
|
aceB
|
Malate synthase (EC 2.3.3.9)
|
||
|
aceA
|
Isocitrate lyase (EC 4.1.3.1)
|
||
|
aceK
|
Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)
|
||
|
Position: -276
Score: 4.5 Sequence: GCTGAAAGGTATCAGC
Locus tag: Ent638_2304
Name: adhE Funciton: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
|||
|
adhE
|
Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
|
||
|
Position: -192
Score: 3.9 Sequence: GCTGAATCGCTCAACC
Locus tag: Ent638_1649
Name: icdA Funciton: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) |
|||
|
icdA
|
Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
|
||
|
Position: -115
Score: 4.3 Sequence: GCTGGCGCGATTCACC
Locus tag: Ent638_0418
Name: fbp Funciton: Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) |
|||
|
fbp
|
Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11)
|
||
|
Position: -162
Score: 4.6 Sequence: GTTGAACCGATTAAGC
Locus tag: Ent638_4052
Name: tpiA Funciton: Triosephosphate isomerase (EC 5.3.1.1) |
|||
|
tpiA
|
Triosephosphate isomerase (EC 5.3.1.1)
|
||
|
Position: -252
Score: 4.4 Sequence: GGTGAATCGGTTCAGA
Locus tag: Ent638_0659
Name: pdhR Funciton: Transcriptional repressor for pyruvate dehydrogenase, GntR family
Locus tag: Ent638_0660
Name: aceE Funciton: Pyruvate dehydrogenase E1 component (EC 1.2.4.1)
Locus tag: Ent638_0661
Name: aceF Funciton: Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)
Locus tag: Ent638_0662
Name: lpdA Funciton: Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex (EC 1.8.1.4) @ Dihydrolipoamide dehydrogenase (EC 1.8.1.4) |
|||
|
pdhR
|
Transcriptional repressor for pyruvate dehydrogenase, GntR family
|
||
|
aceE
|
Pyruvate dehydrogenase E1 component (EC 1.2.4.1)
|
||
|
aceF
|
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)
|
||
|
lpdA
|
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex (EC 1.8.1.4) @ Dihydrolipoamide dehydrogenase (EC 1.8.1.4)
|
||
|
Position: -87
Score: 3.7 Sequence: ATTGACACGATTCCGC
Locus tag: Ent638_1675
Name: gapA Funciton: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Locus tag: Ent638_1674
Name: yeaD Funciton: Aldose 1-epimerase family protein YeaD |
|||
|
gapA
|
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
|
||
|
yeaD
|
Aldose 1-epimerase family protein YeaD
|
||
|
Position: -66
Score: 4.3 Sequence: ACTTTATCGATTCAGC
Locus tag: Ent638_0123
Name: gpmM Funciton: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)
Locus tag: Ent638_0122
Name: yibP Funciton: murein hydrolase
Locus tag: Ent638_0121
Name: yibQ Funciton: protein of unknown function DUF610 |
|||
|
gpmM
|
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)
|
||
|
yibP
|
murein hydrolase
|
||
|
yibQ
|
protein of unknown function DUF610
|
||
|
Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |