Regulon of FruR in Citrobacter koseri ATCC BAA-895

Properties
Regulator type:	Transcription factor
TF locus tag:	CKO_03297
Regulator family:	LacI
Regulation mode:	activator (repressor)
Biological process:	Central carbohydrate metabolism
Effector:	Fructose-1-phosphate; Fructose-1,6-diphosphate
Regulog:	FruR - Enterobacteriales
Statistics of regulated genes:
- Genes	49
- Operons	22
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 213 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - FruR
By TF family - LacI
By effector - Fructose-1-phosphate
By effector - Fructose-1,6-diphosphate
By pathway - Central carbohydrate metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -247 Score: 3.9 Sequence: GCTGAATCGCTCAACC Locus tag: CKO_01835 Name: icdA Funciton: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
	CKO_01835	icdA	Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
Position: 26 Score: 5.1 Sequence: CTTGAAACGTTTCAGC Locus tag: CKO_00613 Name: fruB Funciton: Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69) Locus tag: CKO_00614 Name: fruK Funciton: 1-phosphofructokinase (EC 2.7.1.56) Locus tag: CKO_00615 Name: fruA Funciton: PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69)
	CKO_00613	fruB	Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69)
	CKO_00614	fruK	1-phosphofructokinase (EC 2.7.1.56)
	CKO_00615	fruA	PTS system, fructose-specific IIB component (EC 2.7.1.69) / PTS system, fructose-specific IIC component (EC 2.7.1.69)
Position: -128 Score: 5.1 Sequence: CCTGAATCAATTCAGC Locus tag: CKO_03085 Name: pfkA Funciton: 6-phosphofructokinase (EC 2.7.1.11)
	CKO_03085	pfkA	6-phosphofructokinase (EC 2.7.1.11)
Position: -287 Score: 4 Sequence: GGTGAATCGATATTTT Locus tag: CKO_04825 Name: pckA Funciton: Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)
	CKO_04825	pckA	Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49)
Position: -221 Score: 4.9 Sequence: CTTGAATGGTTTCAGC Locus tag: CKO_01709 Name: pykF Funciton: Pyruvate kinase (EC 2.7.1.40)
	CKO_01709	pykF	Pyruvate kinase (EC 2.7.1.40)
Position: -102 Score: 4.6 Sequence: GCTTGAACGATTCACC Locus tag: CKO_01725 Name: ppsA Funciton: Phosphoenolpyruvate synthase (EC 2.7.9.2)
	CKO_01725	ppsA	Phosphoenolpyruvate synthase (EC 2.7.9.2)
Position: -134 Score: 4.9 Sequence: GCTGAAACGATAAAGT Locus tag: CKO_00412 Name: glk Funciton: Glucokinase (EC 2.7.1.2)
	CKO_00412	glk	Glucokinase (EC 2.7.1.2)
Position: -47 Score: 4.6 Sequence: GCTGAATCGTTAAGGT Locus tag: CKO_04789 Name: nirB Funciton: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4) Locus tag: CKO_04790 Name: nirD Funciton: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
	CKO_04789	nirB	Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
	CKO_04790	nirD	Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
Position: -80 Score: 4 Sequence: TCTGAATCGATTCGAG Locus tag: CKO_01161 Name: manX Funciton: PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69) Locus tag: CKO_01160 Name: manY Funciton: PTS system, mannose-specific IIC component (EC 2.7.1.69) Locus tag: CKO_01159 Name: manZ Funciton: PTS system, mannose-specific IID component (EC 2.7.1.69)
	CKO_01161	manX	PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69)
	CKO_01160	manY	PTS system, mannose-specific IIC component (EC 2.7.1.69)
	CKO_01159	manZ	PTS system, mannose-specific IID component (EC 2.7.1.69)
Position: -219 Score: 5.1 Sequence: GCTGAATCGATTTAAT Locus tag: CKO_00377 Name: ptsH Funciton: PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase Locus tag: CKO_00376 Name: ptsI Funciton: Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) Locus tag: CKO_00375 Name: crr Funciton: PTS system, glucose-specific IIA component (EC 2.7.1.69)
	CKO_00377	ptsH	PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase
	CKO_00376	ptsI	Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
	CKO_00375	crr	PTS system, glucose-specific IIA component (EC 2.7.1.69)
Position: -137 Score: 5.4 Sequence: GCTGAAGCGTTTCAGT Locus tag: CKO_04297 Name: epd Funciton: D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72) Locus tag: CKO_04296 Name: pgk Funciton: Phosphoglycerate kinase (EC 2.7.2.3) Locus tag: CKO_04295 Name: fbaA Funciton: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
	CKO_04297	epd	D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72)
	CKO_04296	pgk	Phosphoglycerate kinase (EC 2.7.2.3)
	CKO_04295	fbaA	Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Position: -283 Score: 3.6 Sequence: ACGGACACGATTCAAC Locus tag: CKO_00508 Name: nuoA Funciton: NADH dehydrogenase I chain A Locus tag: CKO_00509 Name: nuoB Funciton: NADH dehydrogenase I chain B Locus tag: CKO_00510 Name: nuoD Funciton: NADH dehydrogenase I chain C,D Locus tag: CKO_00511 Name: nuoE Funciton: NADH dehydrogenase I chain E Locus tag: CKO_00512 Name: nuoF Funciton: NADH dehydrogenase I chain F Locus tag: CKO_00513 Name: nuoG Funciton: NADH dehydrogenase I chain G Locus tag: CKO_00514 Name: nuoH Funciton: NADH dehydrogenase I chain H Locus tag: CKO_00515 Name: nuoI Funciton: NADH dehydrogenase I chain I Locus tag: CKO_00516 Name: nuoJ Funciton: NADH dehydrogenase I chain J Locus tag: CKO_00517 Name: nuoK Funciton: NADH dehydrogenase I chain K Locus tag: CKO_00518 Name: nuoL Funciton: NADH dehydrogenase I chain L Locus tag: CKO_00519 Name: nuoM Funciton: NADH dehydrogenase I chain M Locus tag: CKO_00520 Name: nuoN Funciton: NADH dehydrogenase I chain N
	CKO_00508	nuoA	NADH dehydrogenase I chain A
	CKO_00509	nuoB	NADH dehydrogenase I chain B
	CKO_00510	nuoD	NADH dehydrogenase I chain C,D
	CKO_00511	nuoE	NADH dehydrogenase I chain E
	CKO_00512	nuoF	NADH dehydrogenase I chain F
	CKO_00513	nuoG	NADH dehydrogenase I chain G
	CKO_00514	nuoH	NADH dehydrogenase I chain H
	CKO_00515	nuoI	NADH dehydrogenase I chain I
	CKO_00516	nuoJ	NADH dehydrogenase I chain J
	CKO_00517	nuoK	NADH dehydrogenase I chain K
	CKO_00518	nuoL	NADH dehydrogenase I chain L
	CKO_00519	nuoM	NADH dehydrogenase I chain M
	CKO_00520	nuoN	NADH dehydrogenase I chain N
Position: -120 Score: 4.1 Sequence: AGTTGAACGATTCAGT Locus tag: CKO_05054 Name: mtlA Funciton: mannitol-specific PTS system, IIABC components
	CKO_05054	mtlA	mannitol-specific PTS system, IIABC components
Position: -227 Score: 4.3 Sequence: GCTGAAGCGAGACACC Locus tag: CKO_04777 Name: crp Funciton: Catabolite gene activator (cAMP receptor protein), CRP family
	CKO_04777	crp	Catabolite gene activator (cAMP receptor protein), CRP family
Position: -303 Score: 4.4 Sequence: TCTGAACCGATTCAAC Locus tag: CKO_03262 Name: aroP Funciton: Aromatic amino acid transport protein AroP
	CKO_03262	aroP	Aromatic amino acid transport protein AroP
Position: -166 Score: 4.1 Sequence: GCTGAACCGATTTCGC Locus tag: CKO_03038 Name: ppc Funciton: Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
	CKO_03038	ppc	Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
Position: -250 Score: 4.8 Sequence: CCTAAAGCGTTTCAGC Locus tag: CKO_03906 Name: aceB Funciton: Malate synthase (EC 2.3.3.9) Locus tag: CKO_03905 Name: aceA Funciton: Isocitrate lyase (EC 4.1.3.1) Locus tag: CKO_03904 Name: aceK Funciton: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)
	CKO_03906	aceB	Malate synthase (EC 2.3.3.9)
	CKO_03905	aceA	Isocitrate lyase (EC 4.1.3.1)
	CKO_03904	aceK	Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)
Position: -265 Score: 4.6 Sequence: GCTGAAAGGTGTCAGC Locus tag: CKO_01318 Name: adhE Funciton: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
	CKO_01318	adhE	Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
Position: -183 Score: 4.6 Sequence: GTTGAACCGATTAAGC Locus tag: CKO_03079 Name: tpiA Funciton: Triosephosphate isomerase (EC 5.3.1.1)
	CKO_03079	tpiA	Triosephosphate isomerase (EC 5.3.1.1)
Position: -253 Score: 4.5 Sequence: GTTGAATCGGTTCAGA Locus tag: CKO_03260 Name: pdhR Funciton: Transcriptional repressor for pyruvate dehydrogenase, GntR family Locus tag: CKO_03259 Name: aceE Funciton: Pyruvate dehydrogenase E1 component (EC 1.2.4.1) Locus tag: CKO_03258 Name: aceF Funciton: Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)
	CKO_03260	pdhR	Transcriptional repressor for pyruvate dehydrogenase, GntR family
	CKO_03259	aceE	Pyruvate dehydrogenase E1 component (EC 1.2.4.1)
	CKO_03258	aceF	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12)
Position: -87 Score: 3.7 Sequence: ATTGACACGATTCCGC Locus tag: CKO_01800 Name: gapA Funciton: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) Locus tag: CKO_01801 Name: yeaD Funciton: Aldose 1-epimerase family protein YeaD
	CKO_01800	gapA	NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
	CKO_01801	yeaD	Aldose 1-epimerase family protein YeaD
Position: -87 Score: 4.1 Sequence: ATTTTATCGATTCAGC Locus tag: CKO_05070 Name: gpmM Funciton: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) Locus tag: CKO_05071 Name: yibP Funciton: murein hydrolase
	CKO_05070	gpmM	2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)
	CKO_05071	yibP	murein hydrolase

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of FruR in Citrobacter koseri ATCC BAA-895

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --