Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Klebsiella pneumoniae subsp. pneumoniae MGH 78578

Properties
Regulator type: Transcription factor
TF locus tag: KPN_01996
Regulator family: LacI
Regulation mode: repressor
Biological process: Purine metabolism
Effector: Hypoxanthine; Guanine
Regulog: PurR - Enterobacteriales
Statistics of regulated genes:
- Genes 39
- Operons 27
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 313 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -156
Score: 5.4
Sequence: ACGCAATCGATTACGC
Locus tag: KPN_00363
Name: tsx
Funciton: nucleoside-specific channel-forming protein
KPN_00363
tsx
nucleoside-specific channel-forming protein
Position: -126
Score: 5.8
Sequence: GCGCAAACGTTTTCGT
Locus tag: KPN_04388
Name: purH
Funciton: phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase
Locus tag: KPN_04387
Name: purD
Funciton: phosphoribosylamine--glycine ligase
KPN_04388
purH
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase
KPN_04387
purD
phosphoribosylamine--glycine ligase
Position: -71
Score: 5.9
Sequence: ACGCAAACGTTTTCTT
Locus tag: KPN_02703
Name: cvpA
Funciton: membrane protein required for colicin V production
Locus tag: KPN_02702
Name: purF
Funciton: amidophosphoribosyltransferase
Locus tag: KPN_02701
Name: ubiX
Funciton: 3-octaprenyl-4-hydroxybenzoate decarboxylase
KPN_02703
cvpA
membrane protein required for colicin V production
KPN_02702
purF
amidophosphoribosyltransferase
KPN_02701
ubiX
3-octaprenyl-4-hydroxybenzoate decarboxylase
Position: -88
Score: 5.5
Sequence: ACGCAACCGTTTTCCT
Locus tag: KPN_00478
Name: purE
Funciton: phosphoribosylaminoimidazole carboxylase catalytic subunit
Locus tag: KPN_00477
Name: purK
Funciton: phosphoribosylaminoimidazole carboxylase ATPase subunit
KPN_00478
purE
phosphoribosylaminoimidazole carboxylase catalytic subunit
KPN_00477
purK
phosphoribosylaminoimidazole carboxylase ATPase subunit
Position: -74
Score: 5.1
Sequence: TCGCAAACGTTTGCTT
Locus tag: KPN_02824
Name: purM
Funciton: phosphoribosylformylglycinamidine cyclo-ligase
Locus tag: KPN_02825
Name: purN
Funciton: phosphoribosylglycinamide formyltransferase 1
KPN_02824
purM
phosphoribosylformylglycinamidine cyclo-ligase
KPN_02825
purN
phosphoribosylglycinamide formyltransferase 1
Position: -147
Score: 3.8
Sequence: AGGTTAACGTTTGCGC
Position: -93
Score: 3.7
Sequence: ATGCAGCCGTTTTTAA
Locus tag: KPN_03837
Name: yhhQ
Funciton: conserved inner membrane protein
KPN_03837
yhhQ
conserved inner membrane protein
Position: -22
Score: 4.8
Sequence: AAGCAAACGGTGATTT
Locus tag: KPN_04576
Name: purA
Funciton: adenylosuccinate synthetase
KPN_04576
purA
adenylosuccinate synthetase
Position: -56
Score: 6
Sequence: ACGCAAACGTTTTCGT
Locus tag: KPN_02364
Name: purT
Funciton: phosphoribosylglycinamide formyltransferase 2
KPN_02364
purT
phosphoribosylglycinamide formyltransferase 2
Position: -91
Score: 5.9
Sequence: ACGCAAACGGTTTCGT
Locus tag: KPN_02882
Name: purL
Funciton: phosphoribosylformylglycinamidine synthase
KPN_02882
purL
phosphoribosylformylglycinamidine synthase
Position: -66
Score: 5.2
Sequence: ATGCAATCGGTTACGC
Locus tag: KPN_02834
Name: guaB
Funciton: inosine-5'-monophosphate dehydrogenase
Locus tag: KPN_02833
Name: guaA
Funciton: GMP synthase
KPN_02834
guaB
inosine-5'-monophosphate dehydrogenase
KPN_02833
guaA
GMP synthase
Position: -400
Score: 5
Sequence: AAGAAAACGTTTTCGC
Locus tag: KPN_02238
Name: prs
Funciton: ribose-phosphate pyrophosphokinase
KPN_02238
prs
ribose-phosphate pyrophosphokinase
Position: -187
Score: 5
Sequence: ACGCAAACGTGTGCGT
Locus tag: KPN_02810
Name: purC
Funciton: phosphoribosylaminoimidazole-succinocarboxamidesynthase
KPN_02810
purC
phosphoribosylaminoimidazole-succinocarboxamidesynthase
Position: -208
Score: 5
Sequence: CCGCAAGCGTTTTCTC
Locus tag: KPN_00040
Name: carA
Funciton: carbamoyl-phosphate synthase small subunit
Locus tag: KPN_00041
Name: carB
Funciton: carbamoyl-phosphate synthase large subunit
KPN_00040
carA
carbamoyl-phosphate synthase small subunit
KPN_00041
carB
carbamoyl-phosphate synthase large subunit
Position: -99
Score: 4.5
Sequence: ACGCAAACGTTCATAT
Locus tag: KPN_03348
Name: serA
Funciton: D-3-phosphoglycerate dehydrogenase
KPN_03348
serA
D-3-phosphoglycerate dehydrogenase
Position: -88
Score: 3.7
Sequence: CAGCAAACGAGGACTG
Locus tag: KPN_00484
Name: folD
Funciton: 5,10-methylene-tetrahydrofolate dehydrogenase
Locus tag: KPN_00483
Name: ybcJ
Funciton: hypothetical protein
KPN_00484
folD
5,10-methylene-tetrahydrofolate dehydrogenase
KPN_00483
ybcJ
hypothetical protein
Position: -111
Score: 4.4
Sequence: AGGTAATCGTTTGCGC
Locus tag: KPN_00974
Name: pyrD
Funciton: dihydroorotate dehydrogenase
KPN_00974
pyrD
dihydroorotate dehydrogenase
Position: -34
Score: 5.2
Sequence: AAGCAACCGGTTACGC
Locus tag: KPN_02878
Name: glnB
Funciton: nitrogen regulatory protein P-II
KPN_02878
glnB
nitrogen regulatory protein P-II
Position: -77
Score: 4.9
Sequence: AGGAAAACGTTTACGC
Locus tag: KPN_01074
Name: pyrC
Funciton: dihydroorotase
KPN_01074
pyrC
dihydroorotase
Position: -133
Score: 4.5
Sequence: AGCCAATCGTTTGCGT
Locus tag: KPN_02876
Name: glyA
Funciton: serine/glycine hydroxymethyltransferase
KPN_02876
glyA
serine/glycine hydroxymethyltransferase
Position: -59
Score: 5.7
Sequence: AGGCAAACGTTTACGT
Position: 28
Score: 4.6
Sequence: GCGCAAACGTTTCCAC
Locus tag: KPN_01996
Name: purR
Funciton: purine nucleotide synthesis repressor
KPN_01996
purR
purine nucleotide synthesis repressor
Position: -68
Score: 4.8
Sequence: TGGCAAACGTTTGCTT
Position: 30
Score: 4.9
Sequence: GCGCAACCGGTTGCGC
Locus tag: KPN_04013
Name: xanP
Funciton: xanthine/uracil permease, NCS2 family
KPN_04013
xanP
xanthine/uracil permease, NCS2 family
Position: -227
Score: 5.1
Sequence: AGGCAAACGATTACCT
Locus tag: KPN_04657
Name: pyrB
Funciton: aspartate carbamoyltransferase catalytic subunit
Locus tag: KPN_04656
Name: pyrI
Funciton: aspartate carbamoyltransferase, regulatory subunit
KPN_04657
pyrB
aspartate carbamoyltransferase catalytic subunit
KPN_04656
pyrI
aspartate carbamoyltransferase, regulatory subunit
Position: -151
Score: 3.7
Sequence: AGTTTAACGTTTTCGT
Position: -119
Score: 4.9
Sequence: ACGCAATCGTTGCCGT
Locus tag: KPN_04124
Name: purP
Funciton: high affinity adenine permease
KPN_04124
purP
high affinity adenine permease
Position: 184
Score: 5.5
Sequence: ACGCAAACGGTTTCCT
Locus tag: KPN_01139
Name: purB
Funciton: adenylosuccinate lyase
KPN_01139
purB
adenylosuccinate lyase
Position: -68
Score: 5.2
Sequence: ACGCAAACGTTTAGTT
Locus tag: KPN_02158
Name: ydiJ
Funciton: predicted FAD-linked oxidoreductase
Locus tag: KPN_02157
Name: ydiI
Funciton: thioesterase superfamily protein
KPN_02158
ydiJ
predicted FAD-linked oxidoreductase
KPN_02157
ydiI
thioesterase superfamily protein
Position: -316
Score: 4.1
Sequence: ACGATAACGTTTGCGC
Position: -129
Score: 3.9
Sequence: AGTTAAACGTTTGCTT
Locus tag: KPN_04465
Name: yjcD
Funciton: putative xanthine/uracil permease
KPN_04465
yjcD
putative xanthine/uracil permease
Position: -107
Score: 4
Sequence: AAGAGAACGTTTGCGT
Locus tag: KPN_03341
Name: gcvT
Funciton: Glycine cleavage system, aminomethyltransferase (EC 2.1.2.10)
Locus tag: KPN_03340
Name: gcvH
Funciton: Glycine cleavage system, aminomethyl moiety carrier protein
Locus tag: KPN_03339
Name: gcvP
Funciton: Glycine cleavage system, glycine decarboxylating dehydrogenase (EC 1.4.4.2)
KPN_03341
gcvT
Glycine cleavage system, aminomethyltransferase (EC 2.1.2.10)
KPN_03340
gcvH
Glycine cleavage system, aminomethyl moiety carrier protein
KPN_03339
gcvP
Glycine cleavage system, glycine decarboxylating dehydrogenase (EC 1.4.4.2)
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