Regulon of PurR in Escherichia coli str. K-12 substr. MG1655
| Regulator type: | Transcription factor |
| TF locus tag: | b1658 |
| Regulator family: | LacI |
| Regulation mode: | repressor |
| Biological process: | Purine metabolism |
| Effector: | Hypoxanthine; Guanine |
| Regulog: | PurR - Enterobacteriales |
| Statistics of regulated genes: | |
| - Genes | 42 |
| - Operons | 28 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Enterobacteriales
- By trascription factor - PurR
- By TF family - LacI
- By effector - Hypoxanthine
- By effector - Guanine
- By pathway - Purine metabolism
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -123
Score: 5.8 Sequence: GCGCAAACGTTTTCGT
Locus tag: b4006
Name: purH Funciton: phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase
Locus tag: b4005
Name: purD Funciton: phosphoribosylamine--glycine ligase |
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purH
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phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase
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purD
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phosphoribosylamine--glycine ligase
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Position: -68
Score: 4.8 Sequence: TGGCAAACGTTTGCTT
Position: 30
Score: 4.9 Sequence: GCGCAACCGGTTGCGC
Locus tag: b3654
Name: xanP Funciton: xanthine/uracil permease, NCS2 family |
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xanP
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xanthine/uracil permease, NCS2 family
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Position: -72
Score: 5.9 Sequence: ACGCAAACGTTTTCTT
Locus tag: b2313
Name: cvpA Funciton: membrane protein required for colicin V production
Locus tag: b2312
Name: purF Funciton: amidophosphoribosyltransferase
Locus tag: b2311
Name: ubiX Funciton: 3-octaprenyl-4-hydroxybenzoate decarboxylase |
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cvpA
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membrane protein required for colicin V production
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purF
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amidophosphoribosyltransferase
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ubiX
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3-octaprenyl-4-hydroxybenzoate decarboxylase
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Position: 184
Score: 5.3 Sequence: ACGCAATCGGTTACCT
Locus tag: b1131
Name: purB Funciton: adenylosuccinate lyase |
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purB
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adenylosuccinate lyase
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Position: -87
Score: 5.5 Sequence: ACGCAACCGTTTTCCT
Locus tag: b0523
Name: purE Funciton: phosphoribosylaminoimidazole carboxylase catalytic subunit
Locus tag: b0522
Name: purK Funciton: phosphoribosylaminoimidazole carboxylase ATPase subunit |
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purE
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phosphoribosylaminoimidazole carboxylase catalytic subunit
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purK
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phosphoribosylaminoimidazole carboxylase ATPase subunit
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Position: -79
Score: 5.1 Sequence: TCGCAAACGTTTGCTT
Locus tag: b2499
Name: purM Funciton: phosphoribosylformylglycinamidine cyclo-ligase
Locus tag: b2500
Name: purN Funciton: phosphoribosylglycinamide formyltransferase 1 |
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purM
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phosphoribosylformylglycinamidine cyclo-ligase
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purN
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phosphoribosylglycinamide formyltransferase 1
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Position: -224
Score: 4.9 Sequence: ACGCAAACGATTTACT
Locus tag: b1687
Name: ydiJ Funciton: predicted FAD-linked oxidoreductase
Locus tag: b1686
Name: ydiI Funciton: thioesterase superfamily protein |
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ydiJ
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predicted FAD-linked oxidoreductase
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ydiI
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thioesterase superfamily protein
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Position: -22
Score: 4.8 Sequence: AAGCAAACGGTGATTT
Locus tag: b4177
Name: purA Funciton: adenylosuccinate synthetase |
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purA
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adenylosuccinate synthetase
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Position: -53
Score: 6 Sequence: ACGCAAACGTTTTCGT
Locus tag: b1849
Name: purT Funciton: phosphoribosylglycinamide formyltransferase 2 |
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purT
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phosphoribosylglycinamide formyltransferase 2
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Position: -92
Score: 5.9 Sequence: ACGCAAACGGTTTCGT
Locus tag: b2557
Name: purL Funciton: phosphoribosylformylglycinamidine synthase |
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purL
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phosphoribosylformylglycinamidine synthase
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Position: -69
Score: 5.2 Sequence: ATGCAATCGGTTACGC
Locus tag: b2508
Name: guaB Funciton: inosine-5'-monophosphate dehydrogenase
Locus tag: b2507
Name: guaA Funciton: GMP synthase |
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guaB
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inosine-5'-monophosphate dehydrogenase
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guaA
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GMP synthase
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Position: -92
Score: 3.7 Sequence: AATAAACCGTTTGCGC
Locus tag: b4246
Name: pyrL Funciton: pyrBI operon leader peptide
Locus tag: b4245
Name: pyrB Funciton: aspartate carbamoyltransferase catalytic subunit
Locus tag: b4244
Name: pyrI Funciton: aspartate carbamoyltransferase, regulatory subunit |
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pyrL
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pyrBI operon leader peptide
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pyrB
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aspartate carbamoyltransferase catalytic subunit
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pyrI
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aspartate carbamoyltransferase, regulatory subunit
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Position: -169
Score: 5 Sequence: ACGCAAACGTGTGCGT
Locus tag: b2476
Name: purC Funciton: phosphoribosylaminoimidazole-succinocarboxamidesynthase |
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purC
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phosphoribosylaminoimidazole-succinocarboxamidesynthase
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Position: -159
Score: 3.7 Sequence: AGGTTAACGATTGCGT
Locus tag: b3471
Name: yhhQ Funciton: conserved inner membrane protein |
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yhhQ
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conserved inner membrane protein
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Position: -236
Score: 4.9 Sequence: GCGCAAGCGTTTTCCA
Locus tag: b0032
Name: carA Funciton: carbamoyl-phosphate synthase small subunit
Locus tag: b0033
Name: carB Funciton: carbamoyl-phosphate synthase large subunit |
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carA
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carbamoyl-phosphate synthase small subunit
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carB
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carbamoyl-phosphate synthase large subunit
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Position: -95
Score: 4.5 Sequence: ACGCAAACGTTCATAT
Locus tag: b2913
Name: serA Funciton: D-3-phosphoglycerate dehydrogenase |
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serA
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D-3-phosphoglycerate dehydrogenase
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Position: -102
Score: 4.2 Sequence: CGGAAAACGTTTGCGT
Locus tag: b0945
Name: pyrD Funciton: dihydroorotate dehydrogenase |
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pyrD
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dihydroorotate dehydrogenase
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Position: -83
Score: 4.7 Sequence: ATGCAAACGATTTCAA
Locus tag: b2553
Name: glnB Funciton: nitrogen regulatory protein P-II |
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glnB
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nitrogen regulatory protein P-II
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Position: -67
Score: 4.3 Sequence: AGGAAAACGTTTCCGC
Locus tag: b1062
Name: pyrC Funciton: dihydroorotase |
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pyrC
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dihydroorotase
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Position: -82
Score: 4.6 Sequence: ACGAAAACGATTGCTT
Locus tag: b0336
Name: codB Funciton: cytosine permease
Locus tag: b0337
Name: codA Funciton: cytosine deaminase |
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codB
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cytosine permease
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codA
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cytosine deaminase
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Position: -134
Score: 4.5 Sequence: AGGTAATCGTTTGCGT
Locus tag: b2551
Name: glyA Funciton: serine/glycine hydroxymethyltransferase |
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glyA
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serine/glycine hydroxymethyltransferase
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Position: -358
Score: 5 Sequence: AAGAAAACGTTTTCGC
Locus tag: b1207
Name: prs Funciton: ribose-phosphate pyrophosphokinase |
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prs
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ribose-phosphate pyrophosphokinase
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Position: -154
Score: 5.6 Sequence: ACGCAATCGATTACGT
Locus tag: b0411
Name: tsx Funciton: nucleoside-specific channel-forming protein |
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tsx
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nucleoside-specific channel-forming protein
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Position: -60
Score: 5.4 Sequence: AGGCAAACGTTTACCT
Position: 28
Score: 4.4 Sequence: GAGCAAACGTTTCCAC
Locus tag: b1658
Name: purR Funciton: purine nucleotide synthesis repressor |
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purR
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purine nucleotide synthesis repressor
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Position: -147
Score: 3.7 Sequence: AGTTTAACGTTTTCGT
Position: -115
Score: 4.9 Sequence: ACGCAATCGTTGCCGT
Locus tag: b3714
Name: purP Funciton: high affinity adenine permease |
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purP
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high affinity adenine permease
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Position: -272
Score: 4.1 Sequence: ACGATAACGTTTGCGC
Position: -130
Score: 3.9 Sequence: AGCTAAACGTTTGCTT
Locus tag: b4064
Name: yjcD Funciton: putative xanthine/uracil permease |
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yjcD
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putative xanthine/uracil permease
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Position: -208
Score: 4 Sequence: AAACAAGAGTTTTCTC
Position: -134
Score: 4.2 Sequence: AAGAAACCGGTTGCGC
Locus tag: b2938
Name: speA Funciton: Biosynthetic arginine decarboxylase (EC 4.1.1.19)
Locus tag: b2937
Name: speB Funciton: Agmatinase (EC 3.5.3.11) |
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speA
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Biosynthetic arginine decarboxylase (EC 4.1.1.19)
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speB
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Agmatinase (EC 3.5.3.11)
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Position: -106
Score: 3.8 Sequence: AAGAGAACGATTGCGT
Locus tag: b2905
Name: gcvT Funciton: Glycine cleavage system, aminomethyltransferase (EC 2.1.2.10)
Locus tag: b2904
Name: gcvH Funciton: Glycine cleavage system, aminomethyl moiety carrier protein
Locus tag: b2903
Name: gcvP Funciton: Glycine cleavage system, glycine decarboxylating dehydrogenase (EC 1.4.4.2) |
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gcvT
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Glycine cleavage system, aminomethyltransferase (EC 2.1.2.10)
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gcvH
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Glycine cleavage system, aminomethyl moiety carrier protein
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gcvP
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Glycine cleavage system, glycine decarboxylating dehydrogenase (EC 1.4.4.2)
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |