Regulog Fnr - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	CRP
Regulation mode:	activator
Biological process:	Anaerobic metabolism
Effector:	Oxygen
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 39 sites [see more]

Member of regulog collections

By taxonomy - Bacillales
By TF family - CRP
By effector - Oxygen
By pathway - Anaerobic metabolism

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	10	5
Bacillus amyloliquefaciens FZB42	8	4
Bacillus pumilus SAFR-032	2	1
Bacillus licheniformis DSM 13	13	7
Anoxybacillus flavithermus WK1	1	1
Geobacillus kaustophilus HTA426	2	2
Bacillus cereus ATCC 14579	2	2
Bacillus halodurans C-125	6	4
Bacillus clausii KSM-K16	1	1
Oceanobacillus iheyensis HTE831	1	1
Paenibacillus sp. JDR-2	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
ywcJ	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -64 score = 6.02949 sequence = TGTGAAATACTTCACA Gene: BSU38060: Formate/nitrite family of transporters	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -87 score = 5.33275 sequence = TGTGAAATGTTTCACA Gene: BLi04135: Formate/nitrite family of transporters	* Anoxybacillus flavithermus WK1 Site: position = -41 score = 5.28145 sequence = TGTGAAAAACATCACA Gene: Aflv_1436: Formate/nitrite family of transporters	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Formate/nitrite family of transporters

CRON 2.
naoX	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	* Paenibacillus sp. JDR-2 Site: position = -40 score = 5.42139 sequence = TGTGAATAATTTCACA Site: position = -205 score = 6.15755 sequence = TGTGAATTAATTCACA Site: position = -271 score = 5.32087 sequence = TGTGAAATTAATCACA Gene: Pjdr2_2160: FAD-dependent pyridine nucleotide-disulphide oxidoreductase	FAD-dependent pyridine nucleotide-disulphide oxidoreductase

CRON 3.
BH0228	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -322 score = 5.82845 sequence = TGTGATGTACGTCACA Gene: BLi02075: Conserved hypothetical protein	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -361 score = 5.71368 sequence = TGTGATATAGATCACA Gene: BH0228: Conserved hypothetical protein	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Conserved hypothetical protein
narG	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -81 score = 5.76498 sequence = TGTGACATAGTTCACA Gene: BSU37280: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	* Bacillus amyloliquefaciens FZB42 Site: position = -81 score = 5.76498 sequence = TGTGACATAGTTCACA Gene: RBAM_034430: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi02074: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC2118: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC0715: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Respiratory nitrate reductase alpha chain (EC 1.7.99.4)
narH	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37270: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034420: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi02073: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC2119: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC0716: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Respiratory nitrate reductase beta chain (EC 1.7.99.4)
narJ	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37260: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034410: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi02072: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1827: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Bacillus cereus ATCC 14579 Gene: BC2120: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC0717: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Respiratory nitrate reductase delta chain (EC 1.7.99.4)
narI	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37250: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034400: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi02071: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1828: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Bacillus cereus ATCC 14579 Gene: BC2121: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC0718: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Respiratory nitrate reductase gamma chain (EC 1.7.99.4)

CRON 4.
coxA	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_1360: Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)	Geobacillus kaustophilus HTA426 Gene: GK1547: Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -224 score = 5.81866 sequence = TGTGATATAAGTCACA Gene: BH0740: Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB1745: Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)	Paenibacillus sp. JDR-2	Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)
coxB	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_1359: Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)	Geobacillus kaustophilus HTA426 Gene: GK1546: Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH0739: Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB1746: Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)	Paenibacillus sp. JDR-2	Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)

CRON 5.
narK	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -80 score = 6.01761 sequence = TGTGATGTAATTCACA Gene: BSU37320: Nitrate/nitrite transporter	* Bacillus amyloliquefaciens FZB42 Site: position = -79 score = 6.01761 sequence = TGTGATGTAATTCACA Gene: RBAM_034470: Nitrate/nitrite transporter	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -95 score = 5.96839 sequence = TGTGACGTAATTCACA Gene: BLi02081: Nitrate/nitrite transporter	Anoxybacillus flavithermus WK1	* Geobacillus kaustophilus HTA426 Site: position = -68 score = 4.6987 sequence = TGTGATCAACCTCACA Gene: GK0766: Nitrate/nitrite transporter	Bacillus cereus ATCC 14579 Gene: BC2128: Nitrate/nitrite transporter	Bacillus halodurans C-125 Gene: BH0232: Nitrate/nitrite transporter	2 Bacillus clausii KSM-K16 Gene: ABC0722: Nitrate/nitrite transporter Gene: ABC0722: Nitrate/nitrite transporter	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Nitrate/nitrite transporter
fnr	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37310: Transcriptional regulator of anaerobic metabolism, FNR family	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034460: Transcriptional regulator of anaerobic metabolism, FNR family	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi02080: Transcriptional regulator of anaerobic metabolism, FNR family	Anoxybacillus flavithermus WK1 Gene: Aflv_2153: Transcriptional regulator of anaerobic metabolism, FNR family	Geobacillus kaustophilus HTA426 Gene: GK0768: Transcriptional regulator of anaerobic metabolism, FNR family	* Bacillus cereus ATCC 14579 Site: position = -192 score = 4.75445 sequence = TGTGACTTTTCTCACA Gene: BC2122: Transcriptional regulator of anaerobic metabolism, FNR family	Bacillus halodurans C-125 Gene: BH0231: Transcriptional regulator of anaerobic metabolism, FNR family	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_5250: Transcriptional regulator of anaerobic metabolism, FNR family	Transcriptional regulator of anaerobic metabolism, FNR family
ywiC	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -92 score = 5.7408 sequence = AGTGATTTAATTCACA Gene: BLi02079: Putative integral inner membrane protein	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Putative integral inner membrane protein

CRON 6.
arfM	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -73 score = 5.61274 sequence = TGTGAAATACATCACT Gene: BSU37290: Anaerobic respiration and fermentation modulator	* Bacillus amyloliquefaciens FZB42 Site: position = -73 score = 5.61274 sequence = TGTGAAATACATCACT Gene: RBAM_034440: Anaerobic respiration and fermentation modulator	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -73 score = 5.7408 sequence = TGTGAATTAAATCACT Gene: BLi02078: Anaerobic respiration and fermentation modulator	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -74 score = 4.80122 sequence = TGTGAACCATGTCACT Gene: BH0229: Anaerobic respiration and fermentation modulator	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Anaerobic respiration and fermentation modulator

CRON 7.
adh	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -90 score = 5.33275 sequence = TGTGAAATGTTTCACA Gene: BLi04290: NAD-dependent aldehyde dehydrogenase domain and Fe-dependent alcohol dehydrogense domain	Anoxybacillus flavithermus WK1 Gene: Aflv_2814: NAD-dependent aldehyde dehydrogenase domain and Fe-dependent alcohol dehydrogense domain	Geobacillus kaustophilus HTA426	* Bacillus cereus ATCC 14579 Site: position = -212 score = 5.33275 sequence = TGTGAAACATTTCACA Site: position = -127 score = 5.33275 sequence = TGTGAAAAATTTCACA Gene: BC4365: NAD-dependent aldehyde dehydrogenase domain and Fe-dependent alcohol dehydrogense domain	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	NAD-dependent aldehyde dehydrogenase domain and Fe-dependent alcohol dehydrogense domain

CRON 8.
ldh	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -60 score = 6.02949 sequence = TGTGAAATACTTCACA Site: position = -83 score = 4.73444 sequence = TGTGAAGTGTTGCACA Gene: BSU03050: L-lactate dehydrogenase (EC 1.1.1.27)	* Bacillus amyloliquefaciens FZB42 Site: position = -57 score = 6.02949 sequence = TGTGAAATACTTCACA Site: position = -80 score = 5.38196 sequence = TGTGAAGTATTGCACA Gene: RBAM_003290: L-lactate dehydrogenase (EC 1.1.1.27)	* Bacillus pumilus SAFR-032 Site: position = -54 score = 6.02949 sequence = TGTGAAATACTTCACA Site: position = -77 score = 5.38196 sequence = TGTGAAGTATTGCACA Gene: BPUM_0277: L-lactate dehydrogenase (EC 1.1.1.27)	* Bacillus licheniformis DSM 13 Site: position = -57 score = 5.38196 sequence = TGTGAAGAATTTCACA Site: position = -80 score = 5.38196 sequence = TGTGAAGTATTGCACA Gene: BLi00366: L-lactate dehydrogenase (EC 1.1.1.27)	Anoxybacillus flavithermus WK1 Gene: Aflv_0889: L-lactate dehydrogenase (EC 1.1.1.27)	* Geobacillus kaustophilus HTA426 Site: position = -40 score = 4.8625 sequence = TGTGAATATATTCACA Gene: GK0475: L-lactate dehydrogenase (EC 1.1.1.27)	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -42 score = 4.77386 sequence = TGTGAAAATATTCACA Site: position = -217 score = 5.98027 sequence = TGTGAAATATTTCACA Site: position = -274 score = 5.98027 sequence = TGTGAAATATTTCACA Gene: BH3937: L-lactate dehydrogenase (EC 1.1.1.27)	* Bacillus clausii KSM-K16 Site: position = -66 score = 5.42139 sequence = TGTGAAATAATGCACA Site: position = -43 score = 5.42139 sequence = TGTGAATAATTTCACA Gene: ABC2872: L-lactate dehydrogenase (EC 1.1.1.27)	* Oceanobacillus iheyensis HTE831 Site: position = -66 score = 5.98027 sequence = TGTGAAATATTTCACA Gene: OB3279: L-lactate dehydrogenase (EC 1.1.1.27)	Paenibacillus sp. JDR-2	L-lactate dehydrogenase (EC 1.1.1.27)
lctP	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU03060: L-lactate permease	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_0278: L-lactate permease	Bacillus licheniformis DSM 13 Gene: BLi00367: L-lactate permease	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH3936: L-lactate permease	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	L-lactate permease

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Fnr - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --