Regulog NreC - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	OmpR
Regulation mode:	activator
Biological process:	Nitrate and nitrite respiration
Effector:	NreB, sensor histidine kinase (Nitrate, Nitrite)
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 17 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - OmpR
By effector - NreB, sensor histidine kinase (Nitrate, Nitrite)
By pathway - Nitrate and nitrite respiration

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	12	3
Staphylococcus capitis SK14	12	3
Staphylococcus epidermidis ATCC 12228	11	3
Staphylococcus carnosus subsp. carnosus TM300	13	3
Staphylococcus haemolyticus JCSC1435	11	3
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Macrococcus caseolyticus JCSC5402	12	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
nirR	* Staphylococcus aureus subsp. aureus N315 Site: position = -93 score = 5.83193 sequence = ATCAGGGAATTCCCTGAT Gene: SA2189: conserved protein, iron chelatase like	* Staphylococcus capitis SK14 Site: position = -93 score = 5.64878 sequence = ATAAGGGTATTCCCTACT Gene: STACA0001_1076: conserved protein, iron chelatase like	Staphylococcus epidermidis ATCC 12228 Gene: SE1979: conserved protein, iron chelatase like	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -93 score = 5.80229 sequence = ATAAGGGGATTCCCTATT Gene: Sca_1899: conserved protein, iron chelatase like	Staphylococcus haemolyticus JCSC1435 Gene: SH0650: conserved protein, iron chelatase like	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -118 score = 5.45977 sequence = TATAGGGAAATCCCTATT Gene: MCCL_1342: conserved protein, iron chelatase like	conserved protein, iron chelatase like
sirA	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1898: syroheme synthase	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1341: syroheme synthase	syroheme synthase
nasD	Staphylococcus aureus subsp. aureus N315 Gene: SA2188: assimilatory nitrite reductase, large subunit	Staphylococcus capitis SK14 Gene: STACA0001_1077: assimilatory nitrite reductase, large subunit	* Staphylococcus epidermidis ATCC 12228 Site: position = -174 score = 5.76723 sequence = ATTAGGGAAATCCCCGAT Gene: SE1978: assimilatory nitrite reductase, large subunit	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1897: assimilatory nitrite reductase, large subunit	* Staphylococcus haemolyticus JCSC1435 Site: position = -170 score = 5.83775 sequence = ATTAGGGAATTCCCCGAT Gene: SH0651: assimilatory nitrite reductase, large subunit	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1340: assimilatory nitrite reductase, large subunit	assimilatory nitrite reductase, large subunit
nasE	Staphylococcus aureus subsp. aureus N315 Gene: SA2187: assimilatory nitrite reductase, small subunit	Staphylococcus capitis SK14 Gene: STACA0001_1078: assimilatory nitrite reductase, small subunit	Staphylococcus epidermidis ATCC 12228 Gene: SE1977: assimilatory nitrite reductase, small subunit	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1896: assimilatory nitrite reductase, small subunit	Staphylococcus haemolyticus JCSC1435 Gene: SH0652: assimilatory nitrite reductase, small subunit	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1339: assimilatory nitrite reductase, small subunit	assimilatory nitrite reductase, small subunit
nasF	Staphylococcus aureus subsp. aureus N315 Gene: SA2186: uroporphyrin-III C-methyl transferase	Staphylococcus capitis SK14 Gene: STACA0001_1079: uroporphyrin-III C-methyltransferase	Staphylococcus epidermidis ATCC 12228 Gene: SE1976: uroporphyrin-III C-methyltransferase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1895: uroporphyrin-III C-methyltransferase	Staphylococcus haemolyticus JCSC1435 Gene: SH0653: uroporphyrin-III C-methyl transferase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1338: uroporphyrin-III C-methyltransferase	uroporphyrin-III C-methyl transferase

CRON 2.
narK	* Staphylococcus aureus subsp. aureus N315 Site: position = -184 score = 5.61912 sequence = ATAAGGGAAAATCCTTAT Gene: SA2176: nitrate-nitrite antiporter	* Staphylococcus capitis SK14 Site: position = -172 score = 5.21942 sequence = TTAAGGGTAAATCCTTAT Gene: STACA0001_1087: nitrate-nitrite antiporter	* Staphylococcus epidermidis ATCC 12228 Site: position = -165 score = 5.0428 sequence = ATCAGGGTATGTCCTTAT Gene: SE1968: nitrate-nitrite antiporter	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -157 score = 5.5274 sequence = TTAAGGGAAAGCCCTTAT Gene: Sca_1887: nitrate-nitrite antiporter	* Staphylococcus haemolyticus JCSC1435 Site: position = -141 score = 5.68964 sequence = ATAAGGGAATATCCTTAT Gene: SH0661: nitrate-nitrite antiporter	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0144: nitrate-nitrite antiporter	nitrate-nitrite antiporter

CRON 3.
narG	* Staphylococcus aureus subsp. aureus N315 Site: position = -134 score = 5.88461 sequence = ATTAGGTGATTCCCTAAT Gene: SA2185: respiratory nitrate reductase alpha chain	* Staphylococcus capitis SK14 Site: position = -116 score = 5.63157 sequence = ATTAGGTATTTCCCTAAT Gene: STACA0001_1080: respiratory nitrate reductase alpha chain	* Staphylococcus epidermidis ATCC 12228 Site: position = -113 score = 5.88461 sequence = ATTAGGACATTCCCTAAT Gene: SE1975: respiratory nitrate reductase alpha chain	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -123 score = 5.38968 sequence = TATAGGAGAATCCCTAAT Gene: Sca_1894: respiratory nitrate reductase alpha chain	* Staphylococcus haemolyticus JCSC1435 Site: position = -118 score = 5.88461 sequence = ATTAGGACATTCCCTAAT Gene: SH0654: respiratory nitrate reductase alpha chain	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -85 score = 5.39872 sequence = TTTAGGACATTCCCCAAT Gene: MCCL_0136: respiratory nitrate reductase alpha chain	respiratory nitrate reductase alpha chain
narH	Staphylococcus aureus subsp. aureus N315 Gene: SA2184: respiratory nitrate reductase beta chain	Staphylococcus capitis SK14 Gene: STACA0001_1081: respiratory nitrate reductase beta chain	Staphylococcus epidermidis ATCC 12228 Gene: SE1974: respiratory nitrate reductase beta chain	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1893: respiratory nitrate reductase beta chain	Staphylococcus haemolyticus JCSC1435 Gene: SH0655: respiratory nitrate reductase beta chain	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0137: respiratory nitrate reductase beta chain	respiratory nitrate reductase beta chain
narJ	Staphylococcus aureus subsp. aureus N315 Gene: SA2183: respiratory nitrate reductase molybdenum cofactor assembly chaperone	Staphylococcus capitis SK14 Gene: STACA0001_1082: respiratory nitrate reductase molybdenum cofactor assembly chaperone	Staphylococcus epidermidis ATCC 12228 Gene: SE1973: respiratory nitrate reductase molybdenum cofactor assembly chaperone	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1892: respiratory nitrate reductase molybdenum cofactor assembly chaperone	Staphylococcus haemolyticus JCSC1435 Gene: SH0656: respiratory nitrate reductase molybdenum cofactor assembly chaperone	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0138: respiratory nitrate reductase molybdenum cofactor assembly chaperone	respiratory nitrate reductase molybdenum cofactor assembly chaperone
narI	Staphylococcus aureus subsp. aureus N315 Gene: SA2182: respiratory nitrate reductase gamma chain	Staphylococcus capitis SK14 Gene: STACA0001_1083: respiratory nitrate reductase gamma chain	Staphylococcus epidermidis ATCC 12228 Gene: SE1972: respiratory nitrate reductase gamma chain	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1891: respiratory nitrate reductase gamma chain	Staphylococcus haemolyticus JCSC1435 Gene: SH0657: respiratory nitrate reductase gamma chain	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0139: respiratory nitrate reductase gamma chain	respiratory nitrate reductase gamma chain
nreA	Staphylococcus aureus subsp. aureus N315 Gene: SA2181: nitrate reduction control protein, certain function is unclear	Staphylococcus capitis SK14 Gene: STACA0001_1084: nitrate reduction control protein, certain function is unclear	Staphylococcus epidermidis ATCC 12228 Gene: SE1971: nitrate reduction control protein, certain function is unclear	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1890: nitrate reduction control protein, certain function is unclear	Staphylococcus haemolyticus JCSC1435 Gene: SH0658: nitrate reduction control protein, certain function is unclear	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0140: nitrate reduction control protein, certain function is unclear	nitrate reduction control protein, certain function is unclear
nreB	Staphylococcus aureus subsp. aureus N315 Gene: SA2180: nitrate respiration regulation two-component system, sensor histidine kinase	Staphylococcus capitis SK14 Gene: STACA0001_1085: nitrate respiration regulation two-component system, sensor histidine kinase	Staphylococcus epidermidis ATCC 12228 Gene: SE1970: nitrate respiration regulation two-component system, sensor histidine kinase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1889: nitrate respiration regulation two-component system, sensor histidine kinase	Staphylococcus haemolyticus JCSC1435 Gene: SH0659: nitrate respiration regulation two-component system, sensor histidine kinase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0141: nitrate respiration regulation two-component system, sensor histidine kinase	nitrate respiration regulation two-component system, sensor histidine kinase
nreC	Staphylococcus aureus subsp. aureus N315 Gene: SA2179: nitrate respiration regulation two-component system, response regulator	Staphylococcus capitis SK14 Gene: STACA0001_1086: nitrate respiration regulation two-component system, response regulator	Staphylococcus epidermidis ATCC 12228 Gene: SE1969: nitrate respiration regulation two-component system, response regulator	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1888: nitrate respiration regulation two-component system, response regulator	Staphylococcus haemolyticus JCSC1435 Gene: SH0660: nitrate respiration regulation two-component system, response regulator	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0142: nitrate respiration regulation two-component system, response regulator	nitrate respiration regulation two-component system, response regulator

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NreC - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --