Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog ThiR - Thermoproteales

Properties
Regulator type: Transcription factor
Regulator family: [Other]
Regulation mode: repressor
Biological process: Thiamine transport; Thiamine biosynthesis
Effector: Thiamine phosphate
Phylum: Crenarchaeota
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 22 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Pyrobaculum arsenaticum DSM 13514 3 2
Pyrobaculum calidifontis JCM 11548 3 3
Pyrobaculum aerophilum str. IM2 6 5
Pyrobaculum islandicum DSM 4184 6 5
Thermoproteus neutrophilus V24Sta 6 5
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
thi4
 
Pyrobaculum arsenaticum DSM 13514

Gene: Pars_1498: Thiazole biosynthetic enzyme Thi4
 
Pyrobaculum calidifontis JCM 11548

Gene: Pcal_1555: Thiazole biosynthetic enzyme Thi4
*
Pyrobaculum aerophilum str. IM2

Site:
position = -33
score = 5.22789
sequence = ATAATATTTTTAT

Site:
position = -66
score = 4.8111
sequence = ATAATAAATTTTT

Gene: PAE0175: Thiazole biosynthetic enzyme Thi4
*
Pyrobaculum islandicum DSM 4184

Site:
position = 3
score = 4.45246
sequence = AAAAGATATTTAT

Gene: Pisl_1998: Thiazole biosynthetic enzyme Thi4
*
Thermoproteus neutrophilus V24Sta

Site:
position = -33
score = 4.4476
sequence = AAAATCTATTTAT

Gene: Tneu_1052: Thiazole biosynthetic enzyme Thi4
Thiazole biosynthetic enzyme Thi4
 
CRON 2.
thiDN
 
Pyrobaculum arsenaticum DSM 13514

Gene: Pars_0839: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
 
Pyrobaculum calidifontis JCM 11548

Gene: Pcal_0240: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
*
Pyrobaculum aerophilum str. IM2

Site:
position = -36
score = 5.1814
sequence = ATAAAAATTTTTT

Gene: PAE2535: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
*
Pyrobaculum islandicum DSM 4184

Site:
position = -11
score = 4.76007
sequence = AAAAAATTGTTAT

Gene: Pisl_1419: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
*
Thermoproteus neutrophilus V24Sta

Site:
position = -51
score = 4.44119
sequence = AAAACGTTTTTAT

Gene: Tneu_1881: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
 
CRON 3.
thiT
*
Pyrobaculum arsenaticum DSM 13514

Site:
position = -33
score = 4.41211
sequence = ATAAAATATTAAT

Gene: Pars_2195: Predicted thiamin transporter ThiT
*
Pyrobaculum calidifontis JCM 11548

Site:
position = -33
score = 4.68369
sequence = ATAATGTATTTAT

Gene: Pcal_0348: Predicted thiamin transporter ThiT
*
Pyrobaculum aerophilum str. IM2

Site:
position = -33
score = 4.8111
sequence = AAAAATTTATTAT

Site:
position = -66
score = 5.22789
sequence = ATAAAAATATTAT

Gene: PAE0176: Predicted thiamin transporter ThiT
*
Pyrobaculum islandicum DSM 4184

Site:
position = -35
score = 5.1814
sequence = ATAAAAATTTTTT

Gene: Pisl_1973: Predicted thiamin transporter ThiT
*
Thermoproteus neutrophilus V24Sta

Site:
position = -35
score = 5.1814
sequence = ATAAAAATTTTTT

Gene: Tneu_1075: Predicted thiamin transporter ThiT
Predicted thiamin transporter ThiT
 
CRON 4.
thiC
 
Pyrobaculum arsenaticum DSM 13514
 
Pyrobaculum calidifontis JCM 11548
*
Pyrobaculum aerophilum str. IM2

Site:
position = -18
score = 4.30941
sequence = AAAACTAATTTAT

Gene: PAE0333: Thiamin biosynthesis protein ThiC
*
Pyrobaculum islandicum DSM 4184

Site:
position = -33
score = 4.67292
sequence = AAAATCTTTTTAT

Gene: Pisl_1450: Thiamin biosynthesis protein ThiC
*
Thermoproteus neutrophilus V24Sta

Site:
position = 6
score = 4.39656
sequence = AAAACCTTTTTAT

Gene: Tneu_0530: Thiamin biosynthesis protein ThiC
Thiamin biosynthesis protein ThiC
 
CRON 5.
tenA1
*
Pyrobaculum arsenaticum DSM 13514

Site:
position = -33
score = 5.05399
sequence = ATAAAGTTTTTAT

Gene: Pars_2186: Thiaminase II (EC 3.5.99.2)
*
Pyrobaculum calidifontis JCM 11548

Site:
position = -33
score = 4.17359
sequence = TTAATGTTTTTAT

Gene: Pcal_1316: Thiaminase II (EC 3.5.99.2)
*
Pyrobaculum aerophilum str. IM2

Site:
position = -33
score = 5.37286
sequence = ATAAAATTTTTAT

Gene: PAE0170: Thiaminase II (EC 3.5.99.2)
*
Pyrobaculum islandicum DSM 4184

Site:
position = -33
score = 5.1814
sequence = AAAAAATTTTTAT

Gene: Pisl_1974: Thiaminase II (EC 3.5.99.2)
*
Thermoproteus neutrophilus V24Sta

Site:
position = -33
score = 5.1814
sequence = AAAAAATTTTTAT

Gene: Tneu_1074: Thiaminase II (EC 3.5.99.2)
Thiaminase II (EC 3.5.99.2)
tenA2
 
Pyrobaculum arsenaticum DSM 13514

Gene: Pars_2187: Thiaminase
*
Pyrobaculum calidifontis JCM 11548

Site:
position = -33
score = 4.21416
sequence = AAAAACCTTTTAT

Gene: Pcal_1890: Thiaminase
 
Pyrobaculum aerophilum str. IM2

Gene: PAE0171: Thiaminase
 
Pyrobaculum islandicum DSM 4184

Gene: Pisl_1975: Thiaminase
 
Thermoproteus neutrophilus V24Sta

Gene: Tneu_1073: Thiaminase
Thiaminase
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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