Regulog CtsR - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	CtsR
Regulation mode:	repressor
Biological process:	Heat shock response
Effector:	Heat shock
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 45 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - CtsR
By effector - Heat shock
By pathway - Heat shock response

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	13	6
Staphylococcus capitis SK14	13	6
Staphylococcus epidermidis ATCC 12228	13	6
Staphylococcus carnosus subsp. carnosus TM300	13	6
Staphylococcus haemolyticus JCSC1435	13	6
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	11	5
Macrococcus caseolyticus JCSC5402	9	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
SA1838	* Staphylococcus aureus subsp. aureus N315 Site: position = -106 score = 5.29 sequence = AATCAAATTTGGTCAAA Gene: SA1838: hypothetical protein	* Staphylococcus capitis SK14 Site: position = -109 score = 4.88 sequence = AATCAAATTTGGTCAAT Gene: STACA0001_1994: hypothetical protein	* Staphylococcus epidermidis ATCC 12228 Site: position = -105 score = 5.1 sequence = AATCAAAATTGGTCAAT Gene: SE1631: hypothetical protein	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -105 score = 5.1 sequence = AATCAAAATTGGTCAAT Gene: Sca_1542: hypothetical protein	* Staphylococcus haemolyticus JCSC1435 Site: position = -106 score = 4.88 sequence = AATCAAATTTGGTCAAT Gene: SH1000: hypothetical protein	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -106 score = 4.88 sequence = AATCAAATTTGGTCAAC Gene: SSP0846: hypothetical protein	* Macrococcus caseolyticus JCSC5402 Site: position = -137 score = 5.66 sequence = AATCAAAGAAGGTCAAA Gene: MCCL_1712: hypothetical protein	hypothetical protein

CRON 2.
hrcA	* Staphylococcus aureus subsp. aureus N315 Site: position = -73 score = 5.68 sequence = ATTGACTTACTTTGACC Gene: SA1411: heat-inducible transcriptional repressor HrcA	* Staphylococcus capitis SK14 Site: position = -73 score = 5.68 sequence = ATTGACTTACTTTGACC Gene: STACA0001_1890: heat-inducible transcription repressor HrcA	* Staphylococcus epidermidis ATCC 12228 Site: position = -73 score = 5.68 sequence = ATTGACTTACTTTGACC Gene: SE1269: heat-inducible transcriptional repressor HrcA	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -73 score = 5.68 sequence = ATTGACTTACTTTGACC Gene: Sca_1204: heat-inducible transcriptional repressor HrcA	* Staphylococcus haemolyticus JCSC1435 Site: position = -73 score = 5.52 sequence = GTTGACTTACTTTGACC Gene: SH1334: heat-inducible transcriptional repressor HrcA	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -73 score = 5.68 sequence = ATTGACTTACTTTGACC Gene: SSP1175: heat-inducible transcriptional repressor HrcA	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1234: heat-inducible transcriptional repressor HrcA	heat-inducible transcriptional repressor HrcA
grpE	Staphylococcus aureus subsp. aureus N315 Gene: SA1410: heat shock molecular chaperone protein GrpE	Staphylococcus capitis SK14 Gene: STACA0001_1891: heat shock molecular chaperone protein GrpE	Staphylococcus epidermidis ATCC 12228 Gene: SE1268: heat shock molecular chaperone protein GrpE	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1203: heat shock molecular chaperone protein GrpE	Staphylococcus haemolyticus JCSC1435 Gene: SH1335: heat shock molecular chaperone protein GrpE	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1176: heat shock molecular chaperone protein GrpE	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1233: heat shock molecular chaperone protein GrpE	heat shock molecular chaperone protein GrpE
dnaK	Staphylococcus aureus subsp. aureus N315 Gene: SA1409: chaperone protein DnaK	Staphylococcus capitis SK14 Gene: STACA0001_1892: chaperone protein DnaK	Staphylococcus epidermidis ATCC 12228 Gene: SE1267: chaperone protein DnaK	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1202: chaperone protein DnaK	Staphylococcus haemolyticus JCSC1435 Gene: SH1336: chaperone protein DnaK	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1177: chaperone protein DnaK	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1232: chaperone protein DnaK	chaperone protein DnaK
dnaJ	Staphylococcus aureus subsp. aureus N315 Gene: SA1408: chaperone protein DnaJ	Staphylococcus capitis SK14 Gene: STACA0001_1893: chaperone protein DnaJ	Staphylococcus epidermidis ATCC 12228 Gene: SE1266: chaperone protein DnaJ	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1201: chaperone protein DnaJ	Staphylococcus haemolyticus JCSC1435 Gene: SH1337: chaperone protein DnaJ	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1178: chaperone protein DnaJ	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1231: chaperone protein DnaJ	chaperone protein DnaJ

CRON 3.
groES	* Staphylococcus aureus subsp. aureus N315 Site: position = -86 score = 5.72 sequence = TTTGACCAAATTTGATT Gene: SA1837: GroES protein	* Staphylococcus capitis SK14 Site: position = -86 score = 5.48 sequence = ATTGACCAAATTTGATT Gene: STACA0001_1993: chaperonin GroS	* Staphylococcus epidermidis ATCC 12228 Site: position = -87 score = 5.44 sequence = ATTGACCAATTTTGATT Gene: SE1630: GroES protein	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -131 score = 5.44 sequence = ATTGACCAATTTTGATT Gene: Sca_1541: GroES protein	* Staphylococcus haemolyticus JCSC1435 Site: position = -86 score = 5.48 sequence = ATTGACCAAATTTGATT Gene: SH1001: GroES protein	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0847: co-chaperonin GroES	* Macrococcus caseolyticus JCSC5402 Site: position = -93 score = 6.04 sequence = TTTGACCTTCTTTGATT Gene: MCCL_1711: chaperonin GroES protein	GroES protein
groEL	Staphylococcus aureus subsp. aureus N315 Gene: SA1836: GroEL protein	Staphylococcus capitis SK14 Gene: STACA0001_1992: chaperonin GroL	Staphylococcus epidermidis ATCC 12228 Gene: SE1629: GroEL protein	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1540: GroEL protein	Staphylococcus haemolyticus JCSC1435 Gene: SH1002: groEL protein (60 kDa chaperonin,Heat shock protein 60)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0848: chaperonin GroEL	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1710: chaperonin GroEL protein	GroEL protein

CRON 4.
ctsR	* Staphylococcus aureus subsp. aureus N315 Site: position = -32 score = 6.1 sequence = AGTCAAAGAAGGTCAAA Site: position = -55 score = 5.33 sequence = GGTCAAAATAGGTCATA Gene: SA0480: transcriptional regulator CtsR	* Staphylococcus capitis SK14 Site: position = -30 score = 6.1 sequence = AGTCAAAGAAGGTCAAA Site: position = -53 score = 5.07 sequence = GGTCAAAGGTGGTCATA Gene: STACA0001_0513: transcriptional regulator CtsR	* Staphylococcus epidermidis ATCC 12228 Site: position = -33 score = 6.1 sequence = AGTCAAAGAAGGTCAAA Site: position = -56 score = 5.64 sequence = GGTCAAAGATGGTCATA Gene: SE0284: transcriptional regulator CtsR	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -33 score = 6.1 sequence = AGTCAAAGAAGGTCAAA Site: position = -56 score = 5.41 sequence = GGTCAAAGTTGGTCATA Gene: Sca_0178: transcriptional regulator CtsR	* Staphylococcus haemolyticus JCSC1435 Site: position = -30 score = 6.1 sequence = AGTCAAAGAAGGTCAAA Site: position = -53 score = 5.04 sequence = GGTCAAAGATGCTCATA Gene: SH2487: transcriptional regulator CtsR	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -29 score = 6.1 sequence = AGTCAAAGAAGGTCAAA Site: position = -52 score = 5.41 sequence = GGTCAAAGTTGGTCATA Gene: SSP2234: transcriptional regulator CtsR	* Macrococcus caseolyticus JCSC5402 Site: position = -17 score = 6.1 sequence = AGTCAAAGAAGGTCAAA Gene: MCCL_1889: transcriptional regulator CtsR	transcriptional regulator CtsR
SA0481	Staphylococcus aureus subsp. aureus N315 Gene: SA0481: UvrB/UvrC domain protein	Staphylococcus capitis SK14 Gene: STACA0001_0512: UvrB/UvrC domain protein	Staphylococcus epidermidis ATCC 12228 Gene: SE0285: UvrB/UvrC domain protein	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0179: UvrB/UvrC domain protein	Staphylococcus haemolyticus JCSC1435 Gene: SH2486: UvrB/UvrC domain protein	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2233: UvrB/UvrC domain protein	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1888: UvrB/UvrC domain protein	UvrB/UvrC domain protein
SA0482	Staphylococcus aureus subsp. aureus N315 Gene: SA0482: putative ATP:guanido phosphotransferase	Staphylococcus capitis SK14 Gene: STACA0001_0511: putative ATP:guanido phosphotransferase	Staphylococcus epidermidis ATCC 12228 Gene: SE0286: putative ATP:guanido phosphotransferase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0180: putative ATP:guanido phosphotransferase	Staphylococcus haemolyticus JCSC1435 Gene: SH2485: putative ATP:guanido phosphotransferase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2232: putative ATP:guanido phosphotransferase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1887: putative ATP:guanido phosphotransferase	putative ATP:guanido phosphotransferase
clpC	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1886: putative stress response-related Clp ATPas	putative stress response-related Clp ATPas
clpC	Staphylococcus aureus subsp. aureus N315 Gene: SA0483: putative stress response-related Clp ATPas	Staphylococcus capitis SK14 Gene: STACA0001_0510: putative stress response-related Clp ATPas	Staphylococcus epidermidis ATCC 12228 Gene: SE0287: putative stress response-related Clp ATPas	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0181: putative stress response-related Clp ATPas	Staphylococcus haemolyticus JCSC1435 Gene: SH2484: putative stress response-related Clp ATPas	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2231: putative stress response-related Clp ATPase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1885: putative stress response-related Clp ATPas	putative stress response-related Clp ATPas

CRON 5.
clpP	* Staphylococcus aureus subsp. aureus N315 Site: position = -64 score = 5.86 sequence = TTTGACCAAATTTGACT Gene: SA0723: ATP-dependent protease proteolytic subunit ClpP	* Staphylococcus capitis SK14 Site: position = -64 score = 5.88 sequence = TTTGACCATTTTTGACT Gene: STACA0001_0262: ATP-dependent protease proteolytic subunit ClpP	* Staphylococcus epidermidis ATCC 12228 Site: position = -63 score = 5.88 sequence = TTTGACCATTTTTGACT Gene: SE0551: ATP-dependent protease proteolytic subunit ClpP	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -65 score = 5.88 sequence = TTTGACCATTTTTGACT Gene: Sca_0419: ATP-dependent protease proteolytic subunit ClpP	* Staphylococcus haemolyticus JCSC1435 Site: position = -65 score = 5.88 sequence = TTTGACCATTTTTGACT Gene: SH2121: ATP-dependent protease proteolytic subunit ClpP	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -64 score = 5.59 sequence = TTTGACCATGTTTGACT Gene: SSP1923: ATP-dependent protease proteolytic subunit ClpP	* Macrococcus caseolyticus JCSC5402 Site: position = -73 score = 5.96 sequence = TTTGACTATCTTTGACT Gene: MCCL_0519: ATP-dependent protease proteolytic subunit ClpP	ATP-dependent protease proteolytic subunit ClpP

CRON 6.
clpB	* Staphylococcus aureus subsp. aureus N315 Site: position = -65 score = 6.14 sequence = GGTCAAAGAAAGTCAAA Gene: SA0835: ClpB chaperone	* Staphylococcus capitis SK14 Site: position = -63 score = 6.14 sequence = GGTCAAAGAAAGTCAAA Gene: STACA0001_0152: ClpB chaperone	* Staphylococcus epidermidis ATCC 12228 Site: position = -72 score = 6.14 sequence = GGTCAAAGAAAGTCAAA Gene: SE0674: clpB protein	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -67 score = 5.91 sequence = GGTCAAAGTAAGTCAAA Gene: Sca_0582: ClpB chaperone	* Staphylococcus haemolyticus JCSC1435 Site: position = -70 score = 6.14 sequence = GGTCAAAGAAAGTCAAA Gene: SH1975: ClpB chaperone	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -67 score = 6.14 sequence = GGTCAAAGAAAGTCAAA Gene: SSP1800: ClpB chaperone	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0600: ClpB chaperone	ClpB chaperone

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog CtsR - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --