Regulog HisR - Listeriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	TrpR
Regulation mode:	repressor
Biological process:	Histidine biosynthesis
Effector:	Histidine
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 8 sites [see more]

Member of regulog collections

By taxonomy - Listeriaceae
By trascription factor - HisR
By TF family - TrpR
By effector - Histidine
By pathway - Histidine biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Listeria innocua Clip11262	10	2
Listeria monocytogenes EGD-e	10	2
Listeria seeligeri serovar 1/2b str. SLCC3954	10	2
Listeria welshimeri serovar 6b str. SLCC5334	10	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes					Function

CRON 1.
hisJ	* Listeria innocua Clip11262 Site: position = -116 score = 6.14584 sequence = CATATTAGCACGTTAAAGTG Gene: lin0579: Histidinol-phosphatase (EC 3.1.3.15)	* Listeria monocytogenes EGD-e Site: position = -116 score = 6.06868 sequence = CATATTAGCACGTTAAAGCG Gene: lmo0570: Histidinol-phosphatase (EC 3.1.3.15)	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -107 score = 6.06868 sequence = CATATTAGCACGTTAAAGCG Gene: lse_0478: Histidinol-phosphatase (EC 3.1.3.15)	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -104 score = 5.78764 sequence = CATATTAGCACGTTAAAGCA Gene: lwe0536: Histidinol-phosphatase (EC 3.1.3.15)	Histidinol-phosphatase (EC 3.1.3.15)

CRON 2.
hisZ	* Listeria innocua Clip11262 Site: position = -55 score = 6.14584 sequence = CACTTTAACGTGCTAATATG Gene: lin0578: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	* Listeria monocytogenes EGD-e Site: position = -55 score = 6.06868 sequence = CGCTTTAACGTGCTAATATG Gene: lmo0569: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	* Listeria seeligeri serovar 1/2b str. SLCC3954 Site: position = -54 score = 6.06868 sequence = CGCTTTAACGTGCTAATATG Gene: lse_0477: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	* Listeria welshimeri serovar 6b str. SLCC5334 Site: position = -55 score = 5.78764 sequence = TGCTTTAACGTGCTAATATG Gene: lwe0535: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
hisG	Listeria innocua Clip11262 Gene: lin0577: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Listeria monocytogenes EGD-e Gene: lmo0568: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0476: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0534: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
hisD	Listeria innocua Clip11262 Gene: lin0576: Histidinol dehydrogenase (EC 1.1.1.23)	Listeria monocytogenes EGD-e Gene: lmo0567: Histidinol dehydrogenase (EC 1.1.1.23)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0475: Histidinol dehydrogenase (EC 1.1.1.23)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0533: Histidinol dehydrogenase (EC 1.1.1.23)	Histidinol dehydrogenase (EC 1.1.1.23)
hisB	Listeria innocua Clip11262 Gene: lin0575: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Listeria monocytogenes EGD-e Gene: lmo0566: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0474: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0532: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
hisH	Listeria innocua Clip11262 Gene: lin0574: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Listeria monocytogenes EGD-e Gene: lmo0565: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0473: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0531: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
hisA	Listeria innocua Clip11262 Gene: lin0573: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Listeria monocytogenes EGD-e Gene: lmo0564: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0472: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0530: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
hisF	Listeria innocua Clip11262 Gene: lin0572: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Listeria monocytogenes EGD-e Gene: lmo0563: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0471: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0529: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
hisI	Listeria innocua Clip11262 Gene: lin0571: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Listeria monocytogenes EGD-e Gene: lmo0562: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0470: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0528: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)
hisE	Listeria innocua Clip11262 Gene: lin0570: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Listeria monocytogenes EGD-e Gene: lmo0561: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Listeria seeligeri serovar 1/2b str. SLCC3954 Gene: lse_0469: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Listeria welshimeri serovar 6b str. SLCC5334 Gene: lwe0527: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog HisR - Listeriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --