Regulog LexA - Micrococcineae

Properties
Regulator type:	Transcription factor
Regulator family:	LexA
Regulation mode:	repressor
Biological process:	SOS response
Effector:	DNA damage
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 62 sites [see more]

Member of regulog collections

By trascription factor - LexA
By taxonomy - Micrococcineae
By TF family - LexA
By effector - DNA damage
By pathway - SOS response

Statistics of regulated genes
Genome	Genes	Operons
Arthrobacter aurescens TC1	10	5
Arthrobacter chlorophenolicus A6	10	5
Arthrobacter sp. FB24	10	5
Beutenbergia cavernae DSM 12333	7	4
Brachybacterium faecium DSM 4810	9	5
Brevibacterium linens BL2	7	4
Clavibacter michiganensis subsp. michiganensis NCPPB 382	4	4
Janibacter sp. HTCC2649	6	3
Jonesia denitrificans DSM 20603	8	4
Kocuria rhizophila DC2201	4	3
Kytococcus sedentarius DSM 20547
Leifsonia xyli subsp. xyli str. CTCB07	5	4
Renibacterium salmoninarum ATCC 33209	8	4
Tropheryma whipplei str. Twist

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes															Function

CRON 1.
lexA	* Arthrobacter aurescens TC1 Site: position = -149 score = 5.02795 sequence = TAGAACAAATGTTTGA Site: position = -216 score = 5.48893 sequence = TAGAACACATATTCGA Gene: AAur_1602: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Arthrobacter chlorophenolicus A6 Site: position = -221 score = 5.69239 sequence = TAGAACACATGTTCGA Site: position = -153 score = 5.02795 sequence = TAGAACAAATGTTTGA Gene: Achl_1470: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Arthrobacter sp. FB24 Site: position = -40 score = 5.02795 sequence = TAGAACAAATGTTTGA Site: position = -107 score = 5.48893 sequence = TAGAACACATATTCGA Gene: Arth_1468: SOS-response repressor and protease LexA (EC 3.4.21.88)	Beutenbergia cavernae DSM 12333 Gene: Bcav_2433: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Brachybacterium faecium DSM 4810 Site: position = -167 score = 4.94237 sequence = CCGAACTCCTGTTCGA Site: position = -98 score = 5.05455 sequence = TCGAACACCTGTTTGG Gene: Bfae_10620: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Brevibacterium linens BL2 Site: position = -142 score = 4.99265 sequence = TCGAACATTTATGCGA Site: position = -193 score = 4.89169 sequence = TAGAACGTCTGTTCTA Gene: BlinB01003436: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clavibacter michiganensis subsp. michiganensis NCPPB 382 Site: position = -229 score = 5.22354 sequence = CCGAACATACATTCGA Site: position = -156 score = 4.86254 sequence = TCGAACAGGTGTTTGC Gene: CMM_2018: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Janibacter sp. HTCC2649 Site: position = -103 score = 5.50187 sequence = TCGAACAGATGTTTGA Site: position = -172 score = 5.02537 sequence = TCGAAACGGTGTTCGA Gene: JNB_00180: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Jonesia denitrificans DSM 20603 Site: position = -251 score = 5.23499 sequence = TCGAACATACGTTCGT Site: position = -182 score = 5.43175 sequence = TCGAACAGGTGTTTGA Gene: Jden_1054: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Kocuria rhizophila DC2201 Site: position = -155 score = 5.40682 sequence = TCGAACACATATTTGA Site: position = -222 score = 5.40233 sequence = TAGAACACATCTTCGA Gene: KRH_15760: SOS-response repressor and protease LexA (EC 3.4.21.88)	Kytococcus sedentarius DSM 20547 Gene: Ksed_17230: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Leifsonia xyli subsp. xyli str. CTCB07 Site: position = -198 score = 4.6975 sequence = CCGAATTTATCTTCGA Site: position = -123 score = 5.04106 sequence = TCGAACACATGTTTGT Gene: Lxx15880: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Renibacterium salmoninarum ATCC 33209 Site: position = -52 score = 5.10994 sequence = TAGAACATATATTTGA Site: position = -118 score = 5.35431 sequence = TAGAACATGTTTTCGA Gene: RSal33209_0733: SOS-response repressor and protease LexA (EC 3.4.21.88)	Tropheryma whipplei str. Twist	SOS-response repressor and protease LexA (EC 3.4.21.88)

CRON 2.
recA	* Arthrobacter aurescens TC1 Site: position = -204 score = 5.37033 sequence = TCGAATATCTGTTCGG Gene: AAur_1594: Recombinase A	* Arthrobacter chlorophenolicus A6 Site: position = -156 score = 5.30021 sequence = TCGAATACCTGTTCGG Gene: Achl_1462: Recombinase A	* Arthrobacter sp. FB24 Site: position = -158 score = 5.37033 sequence = TCGAATATCTGTTCGG Gene: Arth_1460: Recombinase A	* Beutenbergia cavernae DSM 12333 Site: position = -185 score = 5.09476 sequence = TCGAACACGCGTTCGC Gene: Bcav_2448: Recombinase A	* Brachybacterium faecium DSM 4810 Site: position = -186 score = 5.24848 sequence = TCGAACGTCTGTTCGG Gene: Bfae_10530: Recombinase A	Brevibacterium linens BL2 Gene: BlinB01003445: Recombinase A	* Clavibacter michiganensis subsp. michiganensis NCPPB 382 Site: position = -213 score = 5.13217 sequence = TCGAATATCCCTTCGA Gene: CMM_2025: Recombinase A	* Janibacter sp. HTCC2649 Site: position = -194 score = 5.42006 sequence = TCGAACACGTGTTCGT Gene: JNB_05200: Recombinase A	* Jonesia denitrificans DSM 20603 Site: position = -208 score = 5.68218 sequence = TCGAACATGTGTTCGG Gene: Jden_1041: Recombinase A	* Kocuria rhizophila DC2201 Site: position = -180 score = 5.31069 sequence = TCGAAGGTATATTCGA Gene: KRH_15840: Recombinase A	Kytococcus sedentarius DSM 20547 Gene: Ksed_17690: Recombinase A	* Leifsonia xyli subsp. xyli str. CTCB07 Site: position = -93 score = 5.46225 sequence = TCGAAGATATGTTCGG Gene: Lxx16030: Recombinase A	* Renibacterium salmoninarum ATCC 33209 Site: position = -116 score = 5.37033 sequence = TCGAATATCTGTTCGG Gene: RSal33209_0722: Recombinase A	Tropheryma whipplei str. Twist Gene: TW611: Recombinase A	Recombinase A
recX	Arthrobacter aurescens TC1 Gene: AAur_1595: Regulatory protein RecX	Arthrobacter chlorophenolicus A6 Gene: Achl_1463: Regulatory protein RecX	Arthrobacter sp. FB24 Gene: Arth_1461: Regulatory protein RecX	Beutenbergia cavernae DSM 12333 Gene: Bcav_2447: Regulatory protein RecX	Brachybacterium faecium DSM 4810 Gene: Bfae_10540: Regulatory protein RecX	Brevibacterium linens BL2 Gene: BlinB01003444: Regulatory protein RecX	Clavibacter michiganensis subsp. michiganensis NCPPB 382 Gene: CMM_2024: Regulatory protein RecX	Janibacter sp. HTCC2649 Gene: JNB_05195: Regulatory protein RecX	Jonesia denitrificans DSM 20603 Gene: Jden_1042: Regulatory protein RecX	Kocuria rhizophila DC2201 Gene: KRH_15830: Regulatory protein RecX	Kytococcus sedentarius DSM 20547 Gene: Ksed_17680: Regulatory protein RecX	Leifsonia xyli subsp. xyli str. CTCB07 Gene: Lxx16000: Regulatory protein RecX	Renibacterium salmoninarum ATCC 33209 Gene: RSal33209_0723: Regulatory protein RecX	Tropheryma whipplei str. Twist	Regulatory protein RecX

CRON 3.
splB	* Arthrobacter aurescens TC1 Site: position = 11 score = 5.60075 sequence = TCGAACATACATTCGA Gene: AAur_1619: DNA repair photolyase	* Arthrobacter chlorophenolicus A6 Site: position = -24 score = 5.72131 sequence = TCGAACATGTTTTCGA Gene: Achl_1488: DNA repair photolyase	* Arthrobacter sp. FB24 Site: position = -25 score = 5.51415 sequence = TCGAACATACCTTCGA Gene: Arth_1485: DNA repair photolyase	* Beutenbergia cavernae DSM 12333 Site: position = -24 score = 5.016 sequence = TCGGACGCGTGTTCGA Gene: Bcav_2004: DNA repair photolyase	* Brachybacterium faecium DSM 4810 Site: position = -24 score = 5.66397 sequence = TCGAACACGCGTTCGA Gene: Bfae_28900: DNA repair photolyase	* Brevibacterium linens BL2 Site: position = -24 score = 5.98927 sequence = TCGAACACGTGTTCGA Gene: BlinB01001502: DNA repair photolyase	* Clavibacter michiganensis subsp. michiganensis NCPPB 382 Site: position = -24 score = 4.96142 sequence = GCGAATGTGTGTTCGA Gene: CMM_0905: DNA repair photolyase	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201	Kytococcus sedentarius DSM 20547	* Leifsonia xyli subsp. xyli str. CTCB07 Site: position = -24 score = 5.76251 sequence = TAGAACATATGTTCGA Gene: Lxx03480: DNA repair photolyase	2 Renibacterium salmoninarum ATCC 33209 Gene: RSal33209_0753: DNA repair photolyase Gene: RSal33209_0754: DNA repair photolyase	Tropheryma whipplei str. Twist	DNA repair photolyase

CRON 4.
uvrA	* Arthrobacter aurescens TC1 Site: position = -29 score = 5.14582 sequence = TCGAAGAAGTTTTCGA Gene: AAur_2080: Excinuclease ABC, subunit A	* Arthrobacter chlorophenolicus A6 Site: position = -29 score = 5.21594 sequence = TCGAAGAAATTTTCGA Gene: Achl_1820: Excinuclease ABC, subunit A	* Arthrobacter sp. FB24 Site: position = -29 score = 5.14582 sequence = TCGAAGAAGTTTTCGA Gene: Arth_2079: Excinuclease ABC, subunit A	* Beutenbergia cavernae DSM 12333 Site: position = -8 score = 5.2329 sequence = TCGAACAGGTGTGCGA Gene: Bcav_2178: Excinuclease ABC, subunit A	* Brachybacterium faecium DSM 4810 Site: position = -44 score = 5.39526 sequence = CCGAACAGCTGTTCGA Gene: Bfae_15150: Excinuclease ABC, subunit A	Brevibacterium linens BL2 Gene: BlinB01000097: Excinuclease ABC, subunit A	Clavibacter michiganensis subsp. michiganensis NCPPB 382 Gene: CMM_1749: Excinuclease ABC, subunit A	Janibacter sp. HTCC2649 Gene: JNB_03565: Excinuclease ABC, subunit A	* Jonesia denitrificans DSM 20603 Site: position = -45 score = 5.30302 sequence = TCGAACATCTGTGCGA Gene: Jden_1251: Excinuclease ABC, subunit A	Kocuria rhizophila DC2201 Gene: KRH_12030: Excinuclease ABC, subunit A	Kytococcus sedentarius DSM 20547 Gene: Ksed_13060: Excinuclease ABC, subunit A	* Leifsonia xyli subsp. xyli str. CTCB07 Site: position = -21 score = 4.99272 sequence = TCGAACAAAACTTCGA Gene: Lxx11470: Excinuclease ABC, subunit A	* Renibacterium salmoninarum ATCC 33209 Site: position = -30 score = 5.43126 sequence = TCGAAGACATTTTCGA Gene: RSal33209_2279: Excinuclease ABC, subunit A	Tropheryma whipplei str. Twist Gene: TW296: Excinuclease ABC, subunit A	Excinuclease ABC, subunit A
PF00702	Arthrobacter aurescens TC1 Gene: AAur_2081: Putative phosphatase, HAD family	Arthrobacter chlorophenolicus A6 Gene: Achl_1821: Putative phosphatase, HAD family	Arthrobacter sp. FB24 Gene: Arth_2080: Putative phosphatase, HAD family	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810	Brevibacterium linens BL2	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201 Gene: KRH_12040: Putative phosphatase, HAD family	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209 Gene: RSal33209_2278: Putative phosphatase, HAD family	Tropheryma whipplei str. Twist	Putative phosphatase, HAD family
PF01553	Arthrobacter aurescens TC1 Gene: AAur_2082: Putative acyltransferase	Arthrobacter chlorophenolicus A6 Gene: Achl_1822: Putative acyltransferase	Arthrobacter sp. FB24 Gene: Arth_2081: Putative acyltransferase	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810	Brevibacterium linens BL2	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201 Gene: KRH_12050: Putative acyltransferase	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209 Gene: RSal33209_2277: Putative acyltransferase	Tropheryma whipplei str. Twist	Putative acyltransferase
uvrC	Arthrobacter aurescens TC1 Gene: AAur_2083: Excinuclease ABC, subunit C	Arthrobacter chlorophenolicus A6 Gene: Achl_1823: Excinuclease ABC, subunit C	Arthrobacter sp. FB24 Gene: Arth_2082: Excinuclease ABC, subunit C	Beutenbergia cavernae DSM 12333 Gene: Bcav_2175: Excinuclease ABC, subunit C	Brachybacterium faecium DSM 4810 Gene: Bfae_15160: Excinuclease ABC, subunit C	Brevibacterium linens BL2 Gene: BlinB01000096: Excinuclease ABC, subunit C	Clavibacter michiganensis subsp. michiganensis NCPPB 382 Gene: CMM_1748: Excinuclease ABC, subunit C	Janibacter sp. HTCC2649 Gene: JNB_03530: Excinuclease ABC, subunit C	Jonesia denitrificans DSM 20603 Gene: Jden_1252: Excinuclease ABC, subunit C	Kocuria rhizophila DC2201 Gene: KRH_12060: Excinuclease ABC, subunit C	Kytococcus sedentarius DSM 20547 Gene: Ksed_13070: Excinuclease ABC, subunit C	Leifsonia xyli subsp. xyli str. CTCB07 Gene: Lxx11480: Excinuclease ABC, subunit C	Renibacterium salmoninarum ATCC 33209 Gene: RSal33209_2276: Excinuclease ABC, subunit C	Tropheryma whipplei str. Twist Gene: TW297: Excinuclease ABC, subunit C	Excinuclease ABC, subunit C

CRON 5.
imuA	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6	Arthrobacter sp. FB24	* Beutenbergia cavernae DSM 12333 Site: position = -53 score = 5.66555 sequence = TCGAACAACTGTTCGA Gene: Bcav_2289: Predicted RecA/RadA recombinase	* Brachybacterium faecium DSM 4810 Site: position = -60 score = 5.36345 sequence = TCGAACCCCTGTTCGA Site: position = -123 score = 4.88266 sequence = TCGCATGCATGTTCGA Gene: Bfae_15760: Predicted RecA/RadA recombinase	* Brevibacterium linens BL2 Site: position = -18 score = 4.84566 sequence = TAGAACACTAGTTCGA Gene: BlinB01000045: Predicted RecA/RadA recombinase	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	* Jonesia denitrificans DSM 20603 Site: position = -76 score = 5.73409 sequence = TCGAACACACGTTCGA Gene: Jden_1185: Predicted RecA/RadA recombinase	Kocuria rhizophila DC2201	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	Predicted RecA/RadA recombinase
imuB	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333 Gene: Bcav_2288: DNA polymerase-like protein PA0670	Brachybacterium faecium DSM 4810 Gene: Bfae_15750: DNA polymerase-like protein PA0670	Brevibacterium linens BL2 Gene: BlinB01000044: DNA polymerase-like protein PA0670	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603 Gene: Jden_1186: DNA polymerase-like protein PA0670	Kocuria rhizophila DC2201	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	DNA polymerase-like protein PA0670
dnaE2	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333 Gene: Bcav_2287: DNA polymerase III alpha subunit (EC 2.7.7.7)	Brachybacterium faecium DSM 4810 Gene: Bfae_15740: DNA polymerase III alpha subunit (EC 2.7.7.7)	Brevibacterium linens BL2 Gene: BlinB01000043: DNA polymerase III alpha subunit (EC 2.7.7.7)	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603 Gene: Jden_1187: DNA polymerase III alpha subunit (EC 2.7.7.7)	Kocuria rhizophila DC2201	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	DNA polymerase III alpha subunit (EC 2.7.7.7)

CRON 6.
Achl_2045	* Arthrobacter aurescens TC1 Site: position = -40 score = 5.46613 sequence = TCGAACATACTTTCGA Gene: AAur_2311: Conserved hypothetical protein	* Arthrobacter chlorophenolicus A6 Site: position = -59 score = 5.85593 sequence = TCGAACACATATTCGA Gene: Achl_2045: Conserved hypothetical protein	* Arthrobacter sp. FB24 Site: position = -108 score = 5.636 sequence = TCGAAGATATATTCGA Gene: Arth_2319: Conserved hypothetical protein	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810	* Brevibacterium linens BL2 Site: position = -33 score = 5.84407 sequence = TCGAACATTTGTTCGA Gene: BlinB01003614: Conserved hypothetical protein	Clavibacter michiganensis subsp. michiganensis NCPPB 382	* Janibacter sp. HTCC2649 Site: position = -80 score = 5.95099 sequence = TCGAACAGATGTTCGA Gene: JNB_01670: Conserved hypothetical protein	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201	Kytococcus sedentarius DSM 20547 Gene: Ksed_16060: Conserved hypothetical protein	Leifsonia xyli subsp. xyli str. CTCB07	* Renibacterium salmoninarum ATCC 33209 Site: position = -101 score = 5.7226 sequence = TCGAATATATATTCGA Gene: RSal33209_3492: Conserved hypothetical protein	Tropheryma whipplei str. Twist	Conserved hypothetical protein
JNB_01675	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810	Brevibacterium linens BL2	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649 Gene: JNB_01675: Conserved hypothetical protein	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201	Kytococcus sedentarius DSM 20547 Gene: Ksed_16050: Conserved hypothetical protein	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	Conserved hypothetical protein
dnaE	Arthrobacter aurescens TC1 Gene: AAur_2310: DNA polymerase III alpha subunit (EC 2.7.7.7)	Arthrobacter chlorophenolicus A6 Gene: Achl_2044: DNA polymerase III alpha subunit (EC 2.7.7.7)	Arthrobacter sp. FB24 Gene: Arth_2318: DNA polymerase III alpha subunit (EC 2.7.7.7)	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810	Brevibacterium linens BL2 Gene: BlinB01003613: DNA polymerase III alpha subunit (EC 2.7.7.7)	* Clavibacter michiganensis subsp. michiganensis NCPPB 382 Site: position = -62 score = 5.62568 sequence = TCGAACATCCGTTCGA Gene: CMM_1518: DNA polymerase III alpha subunit (EC 2.7.7.7)	Janibacter sp. HTCC2649 Gene: JNB_01680: DNA polymerase III alpha subunit (EC 2.7.7.7)	Jonesia denitrificans DSM 20603	* Kocuria rhizophila DC2201 Site: position = -24 score = 5.20389 sequence = TCGAACACAGTTTCGA Gene: KRH_11560: DNA polymerase III alpha subunit (EC 2.7.7.7)	Kytococcus sedentarius DSM 20547 Gene: Ksed_16040: DNA polymerase III alpha subunit (EC 2.7.7.7)	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	DNA polymerase III alpha subunit (EC 2.7.7.7)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LexA - Micrococcineae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --