Regulog CueR - Various betaproteobacteria

Properties
Regulator type:	Transcription factor
Regulator family:	MerR
Regulation mode:	activator (repressor)
Biological process:	Copper resistance
Effector:	Copper ion, (Cu+)
Phylum:	Proteobacteria/beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 7 sites [see more]

Member of regulog collections

By taxonomy - Various betaproteobacteria
By trascription factor - CueR
By TF family - MerR
By effector - Copper ion, (Cu+)
By pathway - Copper resistance

Statistics of regulated genes
Genome	Genes	Operons
Azoarcus sp. EbN1
Thauera sp. MZ1T	1	1
Dechloromonas aromatica RCB
Nitrosomonas europaea ATCC 19718
Nitrosospira multiformis ATCC 25196
Thiobacillus denitrificans	2	1
Chromobacterium violaceum ATCC 12472
Neisseria meningitidis MC58
Laribacter hongkongensis HLHK9
Methylobacillus flagellatus KT
Methylotenera mobilis JLW8	4	3
Methylophilales bacterium HTCC2181

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
cusC	Azoarcus sp. EbN1	Thauera sp. MZ1T	Dechloromonas aromatica RCB	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	* Methylotenera mobilis JLW8 Site: position = -290 score = 5.5509 sequence = ACCTTACAATTGTTGGAAGCT Gene: Mmol_1490: Heavy metal efflux RND outer membrane protein, CzcC family	Methylophilales bacterium HTCC2181	Heavy metal efflux RND outer membrane protein, CzcC family
copA	Azoarcus sp. EbN1	* Thauera sp. MZ1T Site: position = -62 score = 5.54571 sequence = ACCTTCCCACGTTGGCAAGGT Gene: Tmz1t_3243: Copper-translocating P-type ATPase (EC 3.6.3.4)	Dechloromonas aromatica RCB	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	* Thiobacillus denitrificans Site: position = -59 score = 6.02995 sequence = ACCTTGCCATGATGGCAAGGT Gene: Tbd_2266: Copper-translocating P-type ATPase (EC 3.6.3.4)	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8 Gene: Mmol_1491: Copper-translocating P-type ATPase (EC 3.6.3.4)	Methylophilales bacterium HTCC2181	Copper-translocating P-type ATPase (EC 3.6.3.4)
cueR	Azoarcus sp. EbN1	Thauera sp. MZ1T	Dechloromonas aromatica RCB	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_2267: Copper-responsive transcriptional regulator, MerR family	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	* Methylotenera mobilis JLW8 Site: position = -156 score = 5.5509 sequence = AGCTTCCAACAATTGTAAGGT Site: position = -107 score = 4.76718 sequence = ACCTTACAATAGTGGAAAGCA Gene: Mmol_1488: Copper-responsive transcriptional regulator, MerR family	Methylophilales bacterium HTCC2181	Copper-responsive transcriptional regulator, MerR family

CRON 2.
copZ	Azoarcus sp. EbN1	Thauera sp. MZ1T	Dechloromonas aromatica RCB	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	* Methylotenera mobilis JLW8 Site: position = -115 score = 4.76718 sequence = TGCTTTCCACTATTGTAAGGT Site: position = -66 score = 5.5509 sequence = ACCTTACAATTGTTGGAAGCT Gene: Mmol_1489: Copper chaperone	Methylophilales bacterium HTCC2181	Copper chaperone

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog CueR - Various betaproteobacteria

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --