Regulog NanR - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	RpiR
Regulation mode:	repressor
Biological process:	Sialic acid utilization; N-acetylglucosamine utilization
Effector:	N-acetylmannosamine-6-phosphate
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 18 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By TF family - RpiR
By effector - N-acetylmannosamine-6-phosphate
By pathway - Sialic acid utilization
By pathway - N-acetylglucosamine utilization

Statistics of regulated genes
Genome	Genes	Operons
Macrococcus caseolyticus JCSC5402
Staphylococcus aureus subsp. aureus N315	5	4
Staphylococcus capitis SK14
Staphylococcus carnosus subsp. carnosus TM300	6	4
Staphylococcus epidermidis ATCC 12228
Staphylococcus haemolyticus JCSC1435	7	5
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	8	5

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
nanK	Macrococcus caseolyticus JCSC5402	* Staphylococcus aureus subsp. aureus N315 Site: position = -42 score = 6.12542 sequence = ATGAAAATGTTTTTCAA Gene: SA0305: N-acetylmannosamine kinase (EC 2.7.1.60)	Staphylococcus capitis SK14	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -86 score = 6.28652 sequence = ATGAAAATAATTTTCAA Gene: Sca_2390: N-acetylmannosamine kinase (EC 2.7.1.60)	Staphylococcus epidermidis ATCC 12228	* Staphylococcus haemolyticus JCSC1435 Site: position = -84 score = 6.25065 sequence = ATGAAAATATTTTTCAA Gene: SH0281: N-acetylmannosamine kinase (EC 2.7.1.60)	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -90 score = 6.25065 sequence = ATGAAAATATTTTTCAA Gene: SSP0374: N-acetylmannosamine kinase (EC 2.7.1.60)	N-acetylmannosamine kinase (EC 2.7.1.60)

CRON 2.
nanR	Macrococcus caseolyticus JCSC5402	* Staphylococcus aureus subsp. aureus N315 Site: position = -53 score = 6.25065 sequence = TTGAAAATATTTTTCAT Gene: SA0306: Sialic acid utilization regulator NanR, RpiR family	Staphylococcus capitis SK14	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -58 score = 6.25065 sequence = TTGAAAAAAATTTTCAT Gene: Sca_2391: Sialic acid utilization regulator NanR, RpiR family	Staphylococcus epidermidis ATCC 12228	* Staphylococcus haemolyticus JCSC1435 Site: position = -57 score = 6.21478 sequence = TTGAAAAATATTTTCAA Gene: SH0280: Sialic acid utilization regulator NanR, RpiR family	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -58 score = 6.16129 sequence = ATGAAAAACATTTTCAT Gene: SSP0373: Sialic acid utilization regulator NanR, RpiR family	Sialic acid utilization regulator NanR, RpiR family

CRON 3.
nagE	Macrococcus caseolyticus JCSC5402	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus epidermidis ATCC 12228	* Staphylococcus haemolyticus JCSC1435 Site: position = -124 score = 6.12542 sequence = TTGAAAATGTTTTTCAT Gene: SH0358: N-acetylglucosamine specific PTS, EIIABC component	2 Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305* Gene: SSP0234: N-acetylglucosamine specific PTS, EIIABC component Site: position = -85 score = 5.82456 sequence = ATGAAAATATTTTTCGT Gene: SSP0233: N-acetylglucosamine specific PTS, EIIABC component	N-acetylglucosamine specific PTS, EIIABC component
nagB	Macrococcus caseolyticus JCSC5402	Staphylococcus aureus subsp. aureus N315 Gene: SA0527: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)	Staphylococcus capitis SK14 Gene: STACA0001_0462: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)	2 Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0227: Glucosamine-6-phosphate deaminase (EC 3.5.99.6) Gene: Sca_2393: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)	Staphylococcus epidermidis ATCC 12228 Gene: SE0340: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)	Staphylococcus haemolyticus JCSC1435 Gene: SH0278: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)	2 Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0235: Glucosamine-6-phosphate deaminase (EC 3.5.99.6) Gene: SSP2149: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)	Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
nanE	Macrococcus caseolyticus JCSC5402	* Staphylococcus aureus subsp. aureus N315 Site: position = -103 score = 6.25065 sequence = ATGAAAAATATTTTCAA Gene: SA0307: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	Staphylococcus capitis SK14	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -124 score = 6.25065 sequence = ATGAAAATTTTTTTCAA Gene: Sca_2392: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	Staphylococcus epidermidis ATCC 12228	* Staphylococcus haemolyticus JCSC1435 Site: position = -132 score = 6.21478 sequence = TTGAAAATATTTTTCAA Gene: SH0279: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -125 score = 6.16129 sequence = ATGAAAATGTTTTTCAT Gene: SSP0372: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)

CRON 4.
nanA	Macrococcus caseolyticus JCSC5402	* Staphylococcus aureus subsp. aureus N315 Site: position = -132 score = 6.12542 sequence = TTGAAAAACATTTTCAT Gene: SA0304: N-acetylneuraminate lyase (EC 4.1.3.3)	Staphylococcus capitis SK14	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -176 score = 6.28652 sequence = TTGAAAATTATTTTCAT Gene: Sca_2389: N-acetylneuraminate lyase (EC 4.1.3.3)	Staphylococcus epidermidis ATCC 12228	* Staphylococcus haemolyticus JCSC1435 Site: position = -175 score = 6.25065 sequence = TTGAAAAATATTTTCAT Gene: SH0282: N-acetylneuraminate lyase (EC 4.1.3.3)	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -250 score = 6.25065 sequence = TTGAAAAATATTTTCAT Gene: SSP0375: N-acetylneuraminate lyase (EC 4.1.3.3)	N-acetylneuraminate lyase (EC 4.1.3.3)
nanT	Macrococcus caseolyticus JCSC5402	Staphylococcus aureus subsp. aureus N315 Gene: SA0303: N-Acetylneuraminic acid permease	Staphylococcus capitis SK14	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2388: N-Acetylneuraminic acid permease	Staphylococcus epidermidis ATCC 12228	Staphylococcus haemolyticus JCSC1435 Gene: SH0283: N-Acetylneuraminic acid permease	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0376: N-Acetylneuraminic acid permease	N-Acetylneuraminic acid permease

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NanR - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --