Statistics of regulated genes

Genome	Genes	Operons
Geobacter metallireducens GS-15	5	2
Geobacter sulfurreducens PCA	6	2
Geobacter uraniumreducens Rf4	6	2
Geobacter sp. FRC-32
Geobacter sp. M21	1	1
Geobacter lovleyi SZ	6	2
Pelobacter propionicus DSM 2379	7	2
Pelobacter carbinolicus str. DSM 2380	7	2
Desulfuromonas acetoxidans DSM 684	7	2

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes										Function
CRON 1.
thiED	* Geobacter metallireducens GS-15 Site: position = -164 score = 74.19 sequence = CAGCCTGCTGGGGGA... Gene: Gmet_2909: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Geobacter sulfurreducens PCA Site: position = -169 score = 86.31 sequence = CATAGTCTGCTGGGG... Gene: GSU0605: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Geobacter uraniumreducens Rf4 Site: position = -188 score = 78.62 sequence = TTGCCAGCTAGGGGA... Gene: Gura_3851: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Geobacter sp. FRC-32 Gene: Geob_1418: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Geobacter sp. M21 Site: position = -381 score = 80.18 sequence = AAGCCAGCTAGGGGA... Gene: GM21_3528: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Geobacter lovleyi SZ Site: position = -167 score = 65.22 sequence = CGTCGCCCTGGGGGA... Gene: Glov_2763: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Pelobacter propionicus DSM 2379 Site: position = -181 score = 75.03 sequence = TAAGGCCCTGGGGGA... Gene: Ppro_2595: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	*2 Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_2175: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7) Site: position = -169 score = 70.7 sequence = ATAACCGCTAGGGGC... Gene: Pcar_2235: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Desulfuromonas acetoxidans DSM 684 Site: position = -105 score = 68.35 sequence = ATGGCTGCTGGGGGA... Gene: Dace_0922: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)
thiC	Geobacter metallireducens GS-15 Gene: Gmet_2910: Thiamin biosynthesis protein ThiC	Geobacter sulfurreducens PCA Gene: GSU0604: Thiamin biosynthesis protein ThiC	Geobacter uraniumreducens Rf4 Gene: Gura_3852: Thiamin biosynthesis protein ThiC	Geobacter sp. FRC-32 Gene: Geob_1417: Thiamin biosynthesis protein ThiC	Geobacter sp. M21 Gene: GM21_3529: Thiamin biosynthesis protein ThiC	Geobacter lovleyi SZ Gene: Glov_2764: Thiamin biosynthesis protein ThiC	2 Pelobacter propionicus DSM 2379 Gene: Ppro_1034: Thiamin biosynthesis protein ThiC Gene: Ppro_2596: Thiamin biosynthesis protein ThiC	2 Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0337: Thiamin biosynthesis protein ThiC Gene: Pcar_2236: Thiamin biosynthesis protein ThiC	Desulfuromonas acetoxidans DSM 684 Gene: Dace_0923: Thiamin biosynthesis protein ThiC	Thiamin biosynthesis protein ThiC
Ppro_2597	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA	Geobacter uraniumreducens Rf4	Geobacter sp. FRC-32	Geobacter sp. M21	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379 Gene: Ppro_2597: hypothetical protein	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	hypothetical protein
CRON 2.
thiF	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA	Geobacter uraniumreducens Rf4	Geobacter sp. FRC-32	Geobacter sp. M21	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379	* Pelobacter carbinolicus str. DSM 2380 Site: position = -164 score = 71.14 sequence = AGATAGGCCCTGGGG... Gene: Pcar_0611: Sulfur carrier protein adenylyltransferase ThiF	* Desulfuromonas acetoxidans DSM 684 Site: position = -180 score = 68.97 sequence = TGAAAAGCCCTGGGG... Gene: Dace_1222: Sulfur carrier protein adenylyltransferase ThiF	Sulfur carrier protein adenylyltransferase ThiF
thiS	* Geobacter metallireducens GS-15 Site: position = -99 score = 72.26 sequence = CAACTCGCTAGGGGA... Gene: Gmet_2933: Thiamine biosynthesis protein ThiS	* Geobacter sulfurreducens PCA Site: position = -227 score = 60.03 sequence = ATCGAACCGCTAGGG... Gene: GSU0589: Thiamine biosynthesis protein ThiS	* Geobacter uraniumreducens Rf4 Site: position = -177 score = 72.56 sequence = TACATCGCTGGGGGA... Gene: Gura_3658: Thiamine biosynthesis protein ThiS	Geobacter sp. FRC-32 Gene: Geob_1588: Thiamine biosynthesis protein ThiS	Geobacter sp. M21 Gene: GM21_0667: Thiamine biosynthesis protein ThiS	* Geobacter lovleyi SZ Site: position = -154 score = 78.55 sequence = TAAACCGCTAGGGGA... Gene: Glov_0035: Thiamine biosynthesis protein ThiS	* Pelobacter propionicus DSM 2379 Site: position = -146 score = 72.11 sequence = AAAAACGCTGGGGGA... Gene: Ppro_3474: Thiamine biosynthesis protein ThiS	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0610: Thiamine biosynthesis protein ThiS	Desulfuromonas acetoxidans DSM 684 Gene: Dace_1221: Thiamine biosynthesis protein ThiS	Thiamine biosynthesis protein ThiS
thiG	Geobacter metallireducens GS-15 Gene: Gmet_2934: Thiazole synthase	Geobacter sulfurreducens PCA Gene: GSU0588: Thiazole synthase	Geobacter uraniumreducens Rf4 Gene: Gura_3659: Thiazole synthase	Geobacter sp. FRC-32 Gene: Geob_1587: Thiazole synthase	Geobacter sp. M21 Gene: GM21_0666: Thiazole synthase	Geobacter lovleyi SZ Gene: Glov_0036: Thiazole synthase	Pelobacter propionicus DSM 2379 Gene: Ppro_3475: Thiazole synthase	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0609: Thiazole synthase	Desulfuromonas acetoxidans DSM 684 Gene: Dace_1220: Thiazole synthase	Thiazole synthase
thiH	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA	Geobacter uraniumreducens Rf4	Geobacter sp. FRC-32	Geobacter sp. M21	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0608: Thiazole biosynthesis ThiH	Desulfuromonas acetoxidans DSM 684 Gene: Dace_1219: Thiazole biosynthesis ThiH	Thiazole biosynthesis ThiH
thiE	Geobacter metallireducens GS-15 Gene: Gmet_2935: Thiamine monophosphate synthase	Geobacter sulfurreducens PCA Gene: GSU0587: Thiamine monophosphate synthase	Geobacter uraniumreducens Rf4 Gene: Gura_3660: Thiamine monophosphate synthase	Geobacter sp. FRC-32 Gene: Geob_1586: Thiamine monophosphate synthase	Geobacter sp. M21 Gene: GM21_0665: Thiamine monophosphate synthase	Geobacter lovleyi SZ Gene: Glov_0037: Thiamine monophosphate synthase	Pelobacter propionicus DSM 2379 Gene: Ppro_3476: Thiamine monophosphate synthase	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0607: Thiamine monophosphate synthase	Desulfuromonas acetoxidans DSM 684 Gene: Dace_1218: Thiamine monophosphate synthase	Thiamine monophosphate synthase
COG1242	Geobacter metallireducens GS-15 Gene: Gmet_2936: Predicted Fe-S oxidoreductase	Geobacter sulfurreducens PCA Gene: GSU0586: Predicted Fe-S oxidoreductase	Geobacter uraniumreducens Rf4 Gene: Gura_3661: Predicted Fe-S oxidoreductase	Geobacter sp. FRC-32 Gene: Geob_1585: Predicted Fe-S oxidoreductase	Geobacter sp. M21 Gene: GM21_0664: Predicted Fe-S oxidoreductase	Geobacter lovleyi SZ Gene: Glov_0038: Predicted Fe-S oxidoreductase	Pelobacter propionicus DSM 2379 Gene: Ppro_3477: Predicted Fe-S oxidoreductase	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	Predicted Fe-S oxidoreductase

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