Regulog LexA - Clostridia-1

Properties
Regulator type:	Transcription factor
Regulator family:	LexA
Regulation mode:	repressor
Biological process:	SOS response
Effector:	DNA damage
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 27 sites [see more]

Member of regulog collections

By taxonomy - Clostridia-1
By trascription factor - LexA
By TF family - LexA
By effector - DNA damage
By pathway - SOS response

Statistics of regulated genes
Genome	Genes	Operons
Clostridium acetobutylicum ATCC 824	4	3
Clostridium beijerincki NCIMB 8052	7	5
Clostridium botulinum A str. ATCC 3502	2	2
Clostridium butyricum 5521	5	4
Clostridium kluyveri DSM 555	2	2
Clostridium novyi NT	4	3
Clostridium perfringens ATCC 13124	5	4
Clostridium tetani E88	2	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
recA	* Clostridium acetobutylicum ATCC 824 Site: position = -48 score = 5.24985 sequence = TAGAACAAATGTTCGA Gene: CAC1815: Recombination protein A	* Clostridium beijerincki NCIMB 8052 Site: position = -38 score = 5.10156 sequence = TAGAACATAAGTTCGA Gene: Cbei_1216: Recombination protein A	* Clostridium botulinum A str. ATCC 3502 Site: position = -38 score = 5.12331 sequence = AAGAACATAAGTTCGG Gene: CBO2405: Recombination protein A	* Clostridium butyricum 5521 Site: position = -34 score = 5.10156 sequence = TAGAACATAAGTTCGA Gene: CBY_0292: Recombination protein A	* Clostridium kluyveri DSM 555 Site: position = -36 score = 5.2656 sequence = TAGAACATATGTTCTT Gene: CKL_1445: Recombination protein A	* Clostridium novyi NT Site: position = -49 score = 4.92667 sequence = TAGAACAAACGTTCGG Gene: NT01CX_2123: Recombination protein A	* Clostridium perfringens ATCC 13124 Site: position = -35 score = 5.04817 sequence = TAGAACTTATGTTCGG Gene: CPF_1927: Recombination protein A	* Clostridium tetani E88 Site: position = -54 score = 4.99145 sequence = TAGAACAGATGTTCGA Gene: CTC01289: Recombination protein A	Recombination protein A

CRON 2.
Cbei_0030	Clostridium acetobutylicum ATCC 824	* Clostridium beijerincki NCIMB 8052 Site: position = -61 score = 4.67324 sequence = GTGAACATATGTTCTG Site: position = -32 score = 4.84166 sequence = ATGAACATATGTTTGC Gene: Cbei_0030: hypothetical protein	Clostridium botulinum A str. ATCC 3502	* Clostridium butyricum 5521 Site: position = -33 score = 4.84166 sequence = ATGAACATATGTTTGC Gene: CBY_2287: hypothetical protein	Clostridium kluyveri DSM 555	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -131 score = 5.06757 sequence = GCGAACATATGTTTTA Gene: CPF_2895: hypothetical protein	Clostridium tetani E88	hypothetical protein

CRON 3.
lexA	* Clostridium acetobutylicum ATCC 824 Site: position = -84 score = 4.71571 sequence = CAGAACATAAGTTTGC Gene: CAC1832: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clostridium beijerincki NCIMB 8052 Site: position = -68 score = 4.28403 sequence = TAGAACACAAGTTTGC Gene: Cbei_2561: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clostridium botulinum A str. ATCC 3502 Site: position = -71 score = 4.31785 sequence = TTGAACATTAGTTTGC Gene: CBO1795: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clostridium butyricum 5521 Site: position = -68 score = 4.37669 sequence = CAGAACATAGGTTTGC Gene: CBY_0192: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clostridium kluyveri DSM 555 Site: position = -72 score = 4.7691 sequence = TAGAACATAAGTTTGC Gene: CKL_1579: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clostridium novyi NT Site: position = -296 score = 4.77325 sequence = TCGAAAATTTGTTCTA Site: position = -70 score = 4.78169 sequence = TAGAACATTAGTTTGA Gene: NT01CX_2111: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clostridium perfringens ATCC 13124 Site: position = -71 score = 4.60632 sequence = GAGAACATAAGTTTGC Gene: CPF_1364: SOS-response repressor and protease LexA (EC 3.4.21.88)	* Clostridium tetani E88 Site: position = -80 score = 4.93188 sequence = TAGAACATAAGTTTGA Gene: CTC01298: SOS-response repressor and protease LexA (EC 3.4.21.88)	SOS-response repressor and protease LexA (EC 3.4.21.88)

CRON 4.
uvrB	* Clostridium acetobutylicum ATCC 824 Site: position = -29 score = 5.36488 sequence = ACGAACAAATGTTTGA Gene: CAC0502: Excinuclease ABC subunit B	* Clostridium beijerincki NCIMB 8052 Site: position = -31 score = 4.26698 sequence = ACGAATGTCTGTTCGG Gene: Cbei_4864: Excinuclease ABC subunit B	Clostridium botulinum A str. ATCC 3502 Gene: CBO3387: Excinuclease ABC subunit B	* Clostridium butyricum 5521 Site: position = -44 score = 4.57876 sequence = ACGAATGTTTGTTCGA Gene: CBY_1843: Excinuclease ABC subunit B	Clostridium kluyveri DSM 555 Gene: CKL_3572: Excinuclease ABC subunit B	* Clostridium novyi NT Site: position = -29 score = 4.88949 sequence = ATGAACAAATGTTCTT Gene: NT01CX_1274: Excinuclease ABC subunit B	Clostridium perfringens ATCC 13124	Clostridium tetani E88 Gene: CTC02504: Excinuclease ABC subunit B	Excinuclease ABC subunit B
uvrA	Clostridium acetobutylicum ATCC 824 Gene: CAC0503: Excinuclease ABC subunit A	Clostridium beijerincki NCIMB 8052 Gene: Cbei_4863: Excinuclease ABC subunit A	Clostridium botulinum A str. ATCC 3502 Gene: CBO3386: Excinuclease ABC subunit A	Clostridium butyricum 5521 Gene: CBY_1842: Excinuclease ABC subunit A	Clostridium kluyveri DSM 555 Gene: CKL_3571: Excinuclease ABC subunit A	Clostridium novyi NT Gene: NT01CX_1275: Excinuclease ABC subunit A	Clostridium perfringens ATCC 13124 Gene: CPF_0337: Excinuclease ABC subunit A	Clostridium tetani E88 Gene: CTC02503: Excinuclease ABC subunit A	Excinuclease ABC subunit A

CRON 5.
PF06114	Clostridium acetobutylicum ATCC 824	* Clostridium beijerincki NCIMB 8052 Site: position = -65 score = 4.69476 sequence = TTGAACATACGTTCTT Gene: Cbei_0879: Protein of unknown function DUF955	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -76 score = 5.47517 sequence = AAGAACATATGTTCGA Gene: CPF_1607: Protein of unknown function DUF955	Clostridium tetani E88	Protein of unknown function DUF955
CPF_1608	Clostridium acetobutylicum ATCC 824	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1608: putative resolvase	Clostridium tetani E88	putative resolvase
Cbei_0878	Clostridium acetobutylicum ATCC 824	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0878: Cassette chromosome recombinase B	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Cassette chromosome recombinase B

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LexA - Clostridia-1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --