Regulog NanR - Streptococcaceae
| Regulator type: | Transcription factor |
| Regulator family: | RpiR |
| Regulation mode: | repressor |
| Biological process: | Sialic acid utilization |
| Effector: | N-acetylneuraminic acid |
| Phylum: | Firmicutes |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Streptococcaceae
- By TF family - RpiR
- By effector - N-acetylneuraminic acid
- By pathway - Sialic acid utilization
| Genome | Genes | Operons |
|---|---|---|
| Lactococcus lactis subsp. cremoris SK11 | ||
| Lactococcus lactis subsp. lactis Il1403 | ||
| Streptococcus agalactiae 2603V/R | 8 | 1 |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | 8 | 1 |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | 11 | 2 |
| Streptococcus gallolyticus UCN34 | ||
| Streptococcus gordonii str. Challis substr. CH1 | 8 | 1 |
| Streptococcus mitis B6 | 15 | 3 |
| Streptococcus mutans UA159 | ||
| Streptococcus pneumoniae TIGR4 | 15 | 3 |
| Streptococcus pyogenes M1 GAS | 7 | 1 |
| Streptococcus sanguinis SK36 | 9 | 1 |
| Streptococcus suis 05ZYH33 | 2 | 1 |
| Streptococcus thermophilus CNRZ1066 | ||
| Streptococcus uberis 0140J | 7 | 1 |
| Genes | Function | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||||||||
| nanE |
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Streptococcus agalactiae 2603V/R Site: position = -146 score = 5.89384 sequence = TCTGAAACTACTTTCACG Gene: SAG0033: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -113 score = 5.91882 sequence = AATGAAAGTAGTTTCTAA Gene: SDEG_1959: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
*2
Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -104 score = 5.56376 sequence = AATGAAAGTACTTCCTAA Gene: Sez_0241: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) Site: position = -104 score = 5.91882 sequence = AATGAAAGTAGTTTCTAA Gene: Sez_0245: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus gordonii str. Challis substr. CH1 Site: position = -147 score = 6.321 sequence = TCTGAAACTACTTTCAGA Gene: SGO_0118: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus mitis B6 Site: position = -135 score = 6.321 sequence = TCTGAAACTACTTTCAGA Gene: smi_0602: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus pneumoniae TIGR4 Site: position = -136 score = 5.86962 sequence = TCTGAAAGTACTTTTAGA Gene: SP_1685: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus pyogenes M1 GAS Site: position = -113 score = 5.5156 sequence = AATGAAAGTAGATTCTAA Gene: SPy0251: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus sanguinis SK36 Site: position = -252 score = 5.75949 sequence = CCTGAAAGTACTTTCAGG Gene: SSA_0071: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus suis 05ZYH33 Site: position = -147 score = 5.84568 sequence = TCTGAAACTATTTTCAGG Gene: SSU05_1402: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Streptococcus uberis 0140J Site: position = -108 score = 5.11083 sequence = TTTGAAAGTATTATCTAA Site: position = -147 score = 5.96584 sequence = TCTGAAAATAGTTTCAGA Gene: SUB1658: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
| msmK |
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Gene: SSA_0072: Multiple sugar ABC transporter, ATP-binding protein |
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Multiple sugar ABC transporter, ATP-binding protein |
| SGO_0119 |
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Gene: SGO_0119: Predicted beta-D-galactosidase |
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Gene: SSA_0073: Predicted beta-D-galactosidase |
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Predicted beta-D-galactosidase |
| nanU |
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Gene: SAG0034: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
Gene: SDEG_1958: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
Gene: Sez_0246: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
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Gene: SGO_0120: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
Gene: smi_0603: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
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Gene: SP_1683: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
Gene: SPy0252: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
Gene: SSA_0074: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
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Gene: SUB1655: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
Predicted N-acetylneuraminate ABC transporter, substrat-binding protein |
| nanV |
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Gene: SAG0035: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
Gene: SDEG_1957: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
Gene: Sez_0247: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
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Gene: SGO_0121: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
Gene: smi_0604: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
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Gene: SP_1682: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
Gene: SPy0254: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
Gene: SSA_0075: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
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Gene: SUB1657: Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
Predicted N-acetylneuraminate ABC transporter, permease protein 1 |
| nanW |
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Gene: SAG0036: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
Gene: SDEG_1956: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
Gene: Sez_0248: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
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Gene: SGO_0122: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
Gene: smi_0605: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
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Gene: SP_1681: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
Gene: SPy0255: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
Gene: SSA_0076: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
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Gene: SUB1656: Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
Predicted N-acetylneuraminate ABC transporter, permease protein 2 |
| yjhC |
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Gene: SGO_0123: Predicted oxidoreductase (EC 1.1.1.-) |
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Gene: SSA_0077: Predicted oxidoreductase (EC 1.1.1.-) |
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Predicted oxidoreductase (EC 1.1.1.-) |
| nanA |
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Gene: SAG0039: N-acetylneuraminate lyase (EC 4.1.3.3) |
Gene: SDEG_1953: N-acetylneuraminate lyase (EC 4.1.3.3) |
Gene: Sez_0251: N-acetylneuraminate lyase (EC 4.1.3.3) |
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Gene: SGO_0124: N-acetylneuraminate lyase (EC 4.1.3.3) |
*
Streptococcus mitis B6 Site: position = -160 score = 6.20084 sequence = TCTGAAACTACTTTCAAG Gene: smi_0608: N-acetylneuraminate lyase (EC 4.1.3.3) |
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Streptococcus pneumoniae TIGR4 Site: position = -158 score = 6.36916 sequence = TCTGAAACTACTTTCAAA Gene: SP_1676: N-acetylneuraminate lyase (EC 4.1.3.3) |
Gene: SPy0257: N-acetylneuraminate lyase (EC 4.1.3.3) |
Gene: SSA_0078: N-acetylneuraminate lyase (EC 4.1.3.3) |
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Gene: SUB1653: N-acetylneuraminate lyase (EC 4.1.3.3) |
N-acetylneuraminate lyase (EC 4.1.3.3) |
| nanK |
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Gene: SAG0040: N-acetylmannosamine kinase (EC 2.7.1.60) |
Gene: SDEG_1952: N-acetylmannosamine kinase (EC 2.7.1.60) |
Gene: Sez_0252: N-acetylmannosamine kinase (EC 2.7.1.60) |
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Gene: SGO_0125: N-acetylmannosamine kinase (EC 2.7.1.60) |
Gene: smi_0609: N-acetylmannosamine kinase (EC 2.7.1.60) |
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Gene: SP_1675: N-acetylmannosamine kinase (EC 2.7.1.60) |
Gene: SPy0258: N-acetylmannosamine kinase (EC 2.7.1.60) |
Gene: SSA_0079: N-acetylmannosamine kinase (EC 2.7.1.60) |
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Gene: SUB1652: N-acetylmannosamine kinase (EC 2.7.1.60) |
N-acetylmannosamine kinase (EC 2.7.1.60) |
| yjgK |
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Gene: SAG0037: Conserved hypothetical protein |
Gene: SDEG_1955: Conserved hypothetical protein |
Gene: Sez_0249: Conserved hypothetical protein |
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Gene: smi_0606: Conserved hypothetical protein |
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Gene: SUB1654: Conserved hypothetical protein |
Conserved hypothetical protein |
| SDEG_1954 |
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Gene: SAG0038: Predicted membrane protein |
Gene: SDEG_1954: Predicted membrane protein |
Gene: Sez_0250: Predicted membrane protein |
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Gene: smi_0607: Predicted membrane protein |
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Gene: SPy0256: Predicted membrane protein |
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Predicted membrane protein |
| nanP |
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2
Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0242: N-acetylglucosamine-specific PTS system, EIIABC component (EC 2.7.1.69) Gene: Sez_0243: N-acetylglucosamine-specific PTS system, EIIABC component (EC 2.7.1.69) |
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Gene: SP_1684: N-acetylglucosamine-specific PTS system, EIIABC component (EC 2.7.1.69) |
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Gene: SSU05_1401: N-acetylglucosamine-specific PTS system, EIIABC component (EC 2.7.1.69) |
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N-acetylglucosamine-specific PTS system, EIIABC component (EC 2.7.1.69) |
| CRON 2. | ||||||||||||||||
| nanR |
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Gene: SAG0042: Sialic acid utilization transcriptional regulator NanR, RpiR family |
Gene: SDEG_1951: Sialic acid utilization transcriptional regulator NanR, RpiR family |
Gene: Sez_0254: Sialic acid utilization transcriptional regulator NanR, RpiR family |
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Gene: SGO_0127: Sialic acid utilization transcriptional regulator NanR, RpiR family |
*2
Streptococcus mitis B6 Gene: smi_0612: Sialic acid utilization transcriptional regulator NanR, RpiR family Site: position = -96 score = 5.71341 sequence = TTGGAAACTAGTTTCTAA Gene: smi_0792: Sialic acid utilization transcriptional regulator NanR, RpiR family |
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*2
Streptococcus pneumoniae TIGR4 Site: position = -94 score = 5.71341 sequence = TTGGAAACTAGTTTCTAA Gene: SP_1331: Sialic acid utilization transcriptional regulator NanR, RpiR family Gene: SP_1674: Sialic acid utilization transcriptional regulator NanR, RpiR family |
Gene: SPy0259: Sialic acid utilization transcriptional regulator NanR, RpiR family |
Gene: SSA_0081: Sialic acid utilization transcriptional regulator NanR, RpiR family |
Gene: SSU05_1400: Sialic acid utilization transcriptional regulator NanR, RpiR family |
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Gene: SUB1650: Sialic acid utilization transcriptional regulator NanR, RpiR family |
Sialic acid utilization transcriptional regulator NanR, RpiR family |
| nanE2 |
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Gene: smi_0793: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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Gene: SP_1330: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
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N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) |
| nanA2 |
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Gene: smi_0794: N-acetylneuraminate lyase (EC 4.1.3.3) |
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Gene: SP_1329: N-acetylneuraminate lyase (EC 4.1.3.3) |
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N-acetylneuraminate lyase (EC 4.1.3.3) |
| nanT |
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Gene: smi_0795: Predicted sialic acid transporter |
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Gene: SP_1328: Predicted sialic acid transporter |
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Predicted sialic acid transporter |
| SP_1327 |
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Gene: smi_0796: Hypothetical protein |
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Gene: SP_1327: Hypothetical protein |
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Hypothetical protein |
| neuA |
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Gene: SP_1326: Sialidase (EC 3.2.1.18) |
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Sialidase (EC 3.2.1.18) |
| SP_1325 |
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Gene: smi_0797: Predcted oxidoreductase, GFO/IDH/MOCA family |
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Gene: SP_1325: Predcted oxidoreductase, GFO/IDH/MOCA family |
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Predcted oxidoreductase, GFO/IDH/MOCA family |
| nanK2 |
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Gene: smi_0798: N-acetylmannosamine kinase (EC 2.7.1.60) |
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Gene: SP_1324: N-acetylmannosamine kinase (EC 2.7.1.60) |
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N-acetylmannosamine kinase (EC 2.7.1.60) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |