Regulog RosR - Corynebacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	MarR
Regulation mode:	repressor
Biological process:	Peroxide stress response
Effector:	Hydrogen peroxide; Manganese ion, (Mn2+); Iron ion, (Fe2+)
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 43 sites [see more]

Member of regulog collections

By taxonomy - Corynebacteriaceae
By TF family - MarR
By effector - Hydrogen peroxide
By effector - Manganese ion, (Mn2+)
By effector - Iron ion, (Fe2+)
By pathway - Peroxide stress response

Statistics of regulated genes
Genome	Genes	Operons
Corynebacterium amycolatum SK46	3	3
Corynebacterium aurimucosum ATCC 700975	6	5
Corynebacterium diphtheriae NCTC 13129	5	4
Corynebacterium efficiens YS-314	9	8
Corynebacterium glutamicum ATCC 13032	17	10
Corynebacterium jeikeium K411	3	3
Corynebacterium kroppenstedtii DSM 44385	5	4
Corynebacterium urealyticum DSM 7109	5	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
yqjG	* Corynebacterium amycolatum SK46 Site: position = 4 score = 5.16877 sequence = TTGGTGGCATGACAACAA Gene: CORAM0001_1019: Glutathione S-transferase domain protein	* Corynebacterium aurimucosum ATCC 700975 Site: position = -42 score = 5.71942 sequence = TTGTTGACGTATCAAATA Gene: cauri_0351: Glutathione S-transferase domain protein	* Corynebacterium diphtheriae NCTC 13129 Site: position = 19 score = 5.54742 sequence = TTGTTGATATGTCCACAC Gene: DIP1093: Glutathione S-transferase domain protein	* Corynebacterium efficiens YS-314 Site: position = 37 score = 5.63141 sequence = TTGTTGACATATCACATA Gene: CE1359: Glutathione S-transferase domain protein	* Corynebacterium glutamicum ATCC 13032 Site: position = -43 score = 6.02843 sequence = TTGTTGACATATCATCTA Gene: cg1426: Glutathione S-transferase domain protein	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	* Corynebacterium urealyticum DSM 7109 Site: position = -87 score = 5.44857 sequence = TTGGTGACATATCATCCA Gene: cur_0747: Glutathione S-transferase domain protein	Glutathione S-transferase domain protein

CRON 2.
ywcH	Corynebacterium amycolatum SK46	* Corynebacterium aurimucosum ATCC 700975 Site: position = -30 score = 5.28865 sequence = TTGTTGACACGTCACAGA Gene: cauri_1400: Predicted monooxygenase	* Corynebacterium diphtheriae NCTC 13129 Site: position = -66 score = 5.75859 sequence = TTGTTGATATGTCATATA Gene: DIP1436: Predicted monooxygenase	* Corynebacterium efficiens YS-314 Site: position = -43 score = 6.10011 sequence = TTGATGATATATCAACAA Gene: CE1758: Predicted monooxygenase	* Corynebacterium glutamicum ATCC 13032 Site: position = -42 score = 6.06495 sequence = TTGGTGACATATCAACAA Site: position = -72 score = 4.97344 sequence = TTGTTGACGCATCCATTA Gene: cg1848: Predicted monooxygenase	Corynebacterium jeikeium K411	* Corynebacterium kroppenstedtii DSM 44385 Site: position = -54 score = 5.58436 sequence = TTGTTGATATGTCATGTA Gene: ckrop_1424: Predicted monooxygenase	* Corynebacterium urealyticum DSM 7109 Site: position = -39 score = 4.76414 sequence = TAGGTGACATGTCACGTA Gene: cur_1546: Predicted monooxygenase	Predicted monooxygenase
cg1849	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314	Corynebacterium glutamicum ATCC 13032 Gene: cg1849: Hypothetical protein	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Hypothetical protein
msuE	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975 Gene: cauri_1401: FMN reductase (EC 1.5.1.29)	Corynebacterium diphtheriae NCTC 13129 Gene: DIP1437: FMN reductase (EC 1.5.1.29)	Corynebacterium efficiens YS-314 Gene: CE1759: FMN reductase (EC 1.5.1.29)	Corynebacterium glutamicum ATCC 13032 Gene: cg1850: FMN reductase (EC 1.5.1.29)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_1423: FMN reductase (EC 1.5.1.29)	Corynebacterium urealyticum DSM 7109 Gene: cur_1545: FMN reductase (EC 1.5.1.29)	FMN reductase (EC 1.5.1.29)

CRON 3.
cg3084	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -8 score = 5.92845 sequence = TTGTTGACATGACAACAA Gene: CE2614: oxidoreductase	* Corynebacterium glutamicum ATCC 13032 Site: position = -8 score = 6.36669 sequence = TTGTTGATATGTCAACAA Gene: cg3084: oxidoreductase	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_0259: oxidoreductase	Corynebacterium urealyticum DSM 7109 Gene: cur_0259: oxidoreductase	oxidoreductase
cg3085	Corynebacterium amycolatum SK46	* Corynebacterium aurimucosum ATCC 700975 Site: position = -34 score = 6.05484 sequence = TTGTTGATATGTCACCAA Gene: cauri_0737: putative alkanal monooxygenase alpha chain	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE2620: putative alkanal monooxygenase alpha chain	Corynebacterium glutamicum ATCC 13032 Gene: cg3085: putative alkanal monooxygenase alpha chain	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	putative alkanal monooxygenase alpha chain

CRON 4.
cg2329	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -56 score = 5.96874 sequence = TTGTTGATATATCCACAA Gene: CE2021: putative oxidoreductase	* Corynebacterium glutamicum ATCC 13032 Site: position = -57 score = 5.89041 sequence = TTGTTGATATATCTACAA Gene: cg2329: putative oxidoreductase	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	putative oxidoreductase

CRON 5.
msrA	Corynebacterium amycolatum SK46 Gene: CORAM0001_0128: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Corynebacterium aurimucosum ATCC 700975 Gene: cauri_2405: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Corynebacterium diphtheriae NCTC 13129 Gene: DIP2260: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	* Corynebacterium efficiens YS-314 Site: position = -127 score = 5.2552 sequence = TTGTTGATAAAGCAACGA Gene: CE2764: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	* Corynebacterium glutamicum ATCC 13032 Site: position = -133 score = 5.31275 sequence = TTGTTGATATTGCAACGA Gene: cg3236: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Corynebacterium jeikeium K411 Gene: jk0110: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_0108: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Corynebacterium urealyticum DSM 7109 Gene: cur_0121: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)	Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)

CRON 6.
sodA	Corynebacterium amycolatum SK46 Gene: CORAM0001_2076: Superoxide dismutase (EC 1.15.1.1)	Corynebacterium aurimucosum ATCC 700975 Gene: cauri_2406: Superoxide dismutase (EC 1.15.1.1)	Corynebacterium diphtheriae NCTC 13129 Gene: DIP2261: Superoxide dismutase (EC 1.15.1.1)	* Corynebacterium efficiens YS-314 Site: position = -98 score = 5.11203 sequence = TCGTTGCTTTATCAACAA Gene: CE2765: Superoxide dismutase (EC 1.15.1.1)	* Corynebacterium glutamicum ATCC 13032 Site: position = -131 score = 5.17431 sequence = TCGTTGCAATATCAACAA Gene: cg3237: Superoxide dismutase (EC 1.15.1.1)	Corynebacterium jeikeium K411 Gene: jk0112: Superoxide dismutase (EC 1.15.1.1)	Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_0110: Superoxide dismutase (EC 1.15.1.1)	Corynebacterium urealyticum DSM 7109 Gene: cur_0122: Superoxide dismutase (EC 1.15.1.1)	Superoxide dismutase (EC 1.15.1.1)

CRON 7.
rosR	Corynebacterium amycolatum SK46 Gene: CORAM0001_0627: Peroxide stress response transcriptional regulator RosR, MarR family	Corynebacterium aurimucosum ATCC 700975 Gene: cauri_1035: Peroxide stress response transcriptional regulator RosR, MarR family	Corynebacterium diphtheriae NCTC 13129 Gene: DIP1028: Peroxide stress response transcriptional regulator RosR, MarR family	* Corynebacterium efficiens YS-314 Site: position = -170 score = 5.70247 sequence = TTGATGATGCGTCAACAA Gene: CE1273: Peroxide stress response transcriptional regulator RosR, MarR family	* Corynebacterium glutamicum ATCC 13032 Site: position = -169 score = 5.86459 sequence = TTGATGATGTGTCAACAA Gene: cg1324: Peroxide stress response transcriptional regulator RosR, MarR family	* Corynebacterium jeikeium K411 Site: position = -46 score = 5.64481 sequence = TAGTTGATGTATCAACTA Gene: jk2061: Peroxide stress response transcriptional regulator RosR, MarR family	* Corynebacterium kroppenstedtii DSM 44385 Site: position = -176 score = 5.33095 sequence = TTTATGATACATCAACTA Gene: ckrop_0692: Peroxide stress response transcriptional regulator RosR, MarR family	* Corynebacterium urealyticum DSM 7109 Site: position = -46 score = 5.35485 sequence = TAGGTGATGTGTCAACTA Gene: cur_1983: Peroxide stress response transcriptional regulator RosR, MarR family	Peroxide stress response transcriptional regulator RosR, MarR family

CRON 8.
cg1322	* Corynebacterium amycolatum SK46 Site: position = -89 score = 5.75978 sequence = TTGTTGACACGTCAACAC Site: position = -118 score = 5.45961 sequence = TTGTTGACACATCACCAC Gene: CORAM0001_1635: Predicted polyisoprenoid-binding protein	* Corynebacterium aurimucosum ATCC 700975 Site: position = -49 score = 5.688 sequence = TTGTTGTCACGTCAACAA Gene: cauri_2527: Predicted polyisoprenoid-binding protein	* Corynebacterium diphtheriae NCTC 13129 Site: position = -147 score = 5.10726 sequence = TTGTTGACACGTCAATTG Gene: DIP1027: Predicted polyisoprenoid-binding protein	* Corynebacterium efficiens YS-314 Site: position = 9 score = 5.74913 sequence = TTGTTGACGCATCATCAA Gene: CE1272: Predicted polyisoprenoid-binding protein	* Corynebacterium glutamicum ATCC 13032 Site: position = -127 score = 5.97296 sequence = TTGTTGACACATCATCAA Gene: cg1322: Predicted polyisoprenoid-binding protein	* Corynebacterium jeikeium K411 Site: position = -88 score = 5.70653 sequence = TAGTTGATACATCAACTA Gene: jk2060: Predicted polyisoprenoid-binding protein	* Corynebacterium kroppenstedtii DSM 44385 Site: position = -64 score = 5.02796 sequence = TAGTTGATGTGTCACATA Gene: ckrop_0391: Predicted polyisoprenoid-binding protein	* Corynebacterium urealyticum DSM 7109 Site: position = -27 score = 5.35951 sequence = TAGTTGACACATCACCTA Gene: cur_1982: Predicted polyisoprenoid-binding protein	Predicted polyisoprenoid-binding protein

CRON 9.
narK	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129 Gene: DIP0501: Nitrate/nitrite transporter	Corynebacterium efficiens YS-314 Gene: CE1297: Nitrate/nitrite transporter	* Corynebacterium glutamicum ATCC 13032 Site: position = -191 score = 4.26803 sequence = ATGTTGATATAAGCACAA Gene: cg1345: Nitrate/nitrite transporter	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Nitrate/nitrite transporter
narG	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129 Gene: DIP0500: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Corynebacterium efficiens YS-314 Gene: CE1296: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Corynebacterium glutamicum ATCC 13032 Gene: cg1344: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Respiratory nitrate reductase alpha chain (EC 1.7.99.4)
narH	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129 Gene: DIP0499: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Corynebacterium efficiens YS-314 Gene: CE1295: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Corynebacterium glutamicum ATCC 13032 Gene: cg1343: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Respiratory nitrate reductase beta chain (EC 1.7.99.4)
narJ	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129 Gene: DIP0498: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Corynebacterium efficiens YS-314 Gene: CE1294: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Corynebacterium glutamicum ATCC 13032 Gene: cg1342: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Respiratory nitrate reductase delta chain (EC 1.7.99.4)
narI	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129 Gene: DIP0497: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Corynebacterium efficiens YS-314 Gene: CE1293: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Corynebacterium glutamicum ATCC 13032 Gene: cg1341: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Respiratory nitrate reductase gamma chain (EC 1.7.99.4)

CRON 10.
cg1150	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314	* Corynebacterium glutamicum ATCC 13032 Site: position = -42 score = 5.47912 sequence = TTGTTGATACATCAACTT Gene: cg1150: Hypothetical protein	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Hypothetical protein

CRON 11.
poxB	* Corynebacterium amycolatum SK46 Site: position = -38 score = 4.33035 sequence = ATGTTGACGTAGCGACTA Gene: CORAM0001_0264: Pyruvate oxidase (EC 1.2.2.2)	* Corynebacterium aurimucosum ATCC 700975 Site: position = -116 score = 3.99095 sequence = TTGTTGTTAAAGTCACAA Gene: cauri_2195: Pyruvate oxidase (EC 1.2.2.2)	* Corynebacterium diphtheriae NCTC 13129 Site: position = -395 score = 3.619 sequence = TTGAGGTCATATCCACGT Gene: DIP1952: Pyruvate oxidase (EC 1.2.2.2)	Corynebacterium efficiens YS-314	Corynebacterium glutamicum ATCC 13032 Gene: cg2891: Pyruvate oxidase (EC 1.2.2.2)	* Corynebacterium jeikeium K411 Site: position = -8 score = 3.73869 sequence = TTGGAGGCATGGCTAAAA Gene: jk0715: Pyruvate oxidase (EC 1.2.2.2)	* Corynebacterium kroppenstedtii DSM 44385 Site: position = -202 score = 5.25002 sequence = TAGTTGATGTATCATAAA Gene: ckrop_0693: Pyruvate oxidase (EC 1.2.2.2)	Corynebacterium urealyticum DSM 7109	Pyruvate oxidase (EC 1.2.2.2)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog RosR - Corynebacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --