Statistics of regulated genes

Genome	Genes	Operons
Clostridium kluyveri DSM 555	1	1
Clostridium sp. SS2/1
Clostridium cellulolyticum H10	1	1
Clostridium phytofermentans ISDg
Clostridium tetani E88
Clostridium acetobutylicum ATCC 824
Clostridium botulinum A str. ATCC 3502	1	1
Clostridium novyi NT
Clostridium perfringens ATCC 13124	2	1
Clostridium difficile 630	2	2
Clostridium beijerincki NCIMB 8052	3	1
Clostridium sp. OhILAs	3	2
Clostridium sp. L2-50
Clostridium scindens ATCC 35704
Clostridium nexile DSM 1787
Clostridium leptum DSM 753
Clostridium hiranonis DSM 13275
Clostridium butyricum 5521	2	1
Clostridium bolteae ATCC BAA-613
Clostridium bartlettii DSM 16795	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes																					Function
CRON 1.
CBO2829	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	* Clostridium botulinum A str. ATCC 3502 Site: position = -185 score = 43.58 sequence = GGGACTAGATAGCTA... Gene: CBO2829: hypothetical protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CRON 2.
gntR	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_4468: Transcriptional regulator, GntR family	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_2071: Transcriptional regulator, GntR family	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -349 score = 71.28 sequence = TTTTATGGTTTTCTA... Gene: CLOBAR_00647: Transcriptional regulator, GntR family	Transcriptional regulator, GntR family
CRON 3.
pbuO	Clostridium kluyveri DSM 555 Gene: CKL_2693: xanthine/uracil permease family protein	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_0209: xanthine/uracil permease family protein	Clostridium phytofermentans ISDg Gene: null: xanthine/uracil permease family protein	Clostridium tetani E88 Gene: CTC01973: xanthine/uracil permease family protein	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO2901: xanthine/uracil permease family protein	Clostridium novyi NT Gene: NT01CX_2417: xanthine/uracil permease family protein	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1974: xanthine/uracil permease family protein	* Clostridium sp. OhILAs Site: position = -188 score = 69.18 sequence = GAAAGTGTACCTAGG... Gene: Clos_0535: xanthine/uracil permease family protein	Clostridium sp. L2-50 Gene: CLOL250_02773: xanthine/uracil permease family protein	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_03737: xanthine/uracil permease family protein	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01359: xanthine/uracil permease family protein	Clostridium bartlettii DSM 16795	xanthine/uracil permease family protein
CRON 4.
COG3382	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAP0113: Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -150 score = 87.48 sequence = ATATAAAGTTTTCTA... Gene: CPF_1040: Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta	* Clostridium difficile 630 Site: position = -159 score = 81.89 sequence = TAATTTAGTTTTCTA... Gene: CD2392: Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta	* Clostridium beijerincki NCIMB 8052 Site: position = -155 score = 82.03 sequence = TATTTAAGTTTTCTA... Gene: Cbei_3447: Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta	* Clostridium sp. OhILAs Site: position = -157 score = 77.33 sequence = TTTAAGTTTTCTAGG... Gene: Clos_1298: Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta
COG731	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1039: Putative Fe-S oxidoreductase	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3446: Putative Fe-S oxidoreductase	Clostridium sp. OhILAs Gene: Clos_1299: Putative Fe-S oxidoreductase	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	* Clostridium butyricum 5521 Site: position = -165 score = 81.14 sequence = AAGATAAGTTTTCTA... Gene: CBY_1736: Putative Fe-S oxidoreductase	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Putative Fe-S oxidoreductase
ykkD	* Clostridium kluyveri DSM 555 Site: position = -161 score = 79.4 sequence = ATTTAAAGTTTTATA... Gene: CKL_2463: Quaternary ammonium compound-resistance protein sugE	Clostridium sp. SS2/1	* Clostridium cellulolyticum H10 Site: position = -161 score = 81.47 sequence = ATATAGTTTTATAGG... Gene: Ccel_2446: Quaternary ammonium compound-resistance protein sugE	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	* Clostridium difficile 630 Site: position = -175 score = 84.61 sequence = ATAGAGTTTTATAGG... Gene: CD0488: Quaternary ammonium compound-resistance protein sugE	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3445: Quaternary ammonium compound-resistance protein sugE	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_1735: Quaternary ammonium compound-resistance protein sugE	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Quaternary ammonium compound-resistance protein sugE

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