Regulog T-box(Ile) - Bacillales

Properties
Regulator type:	RNA regulatory element
Name:	T-box
RFAM:	RF00230
Regulation mode:
Biological process:	Amino acid metabolism
Effector:	Ile-tRNA
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Bacillales
By RNA motif - T-box
By effector - Ile-tRNA
By pathway - Amino acid metabolism

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	1	1
Bacillus amyloliquefaciens FZB42	1	1
Bacillus pumilus SAFR-032	1	1
Bacillus licheniformis DSM 13	1	1
Anoxybacillus flavithermus WK1	1	1
Geobacillus kaustophilus HTA426	1	1
Bacillus cereus ATCC 14579	8	4
Bacillus halodurans C-125	1	1
Bacillus clausii KSM-K16	1	1
Oceanobacillus iheyensis HTE831	10	3
Paenibacillus sp. JDR-2	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
ileS2	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	* Bacillus cereus ATCC 14579 Site: position = -287 score = 124.5 sequence = CAAATCTGAAGACGA... Gene: BC2164: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	Bacillus halodurans C-125	Bacillus clausii KSM-K16	* Oceanobacillus iheyensis HTE831 Site: position = -291 score = 90.9 sequence = TGAATTCGATGACGA... Gene: OB0362: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	Paenibacillus sp. JDR-2 Gene: Pjdr2_3873: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	Isoleucyl-tRNA synthetase (EC 6.1.1.5)

CRON 2.
brnQ	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	* Bacillus cereus ATCC 14579 Site: position = -278 score = 123.15 sequence = TAAAAATTCATTGAC... Gene: BC1441: Branched-chain amino acid transport system carrier protein BraB	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Branched-chain amino acid transport system carrier protein BraB

CRON 3.
Pjdr2_4149	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	* Paenibacillus sp. JDR-2 Site: position = -282 score = 119.75 sequence = GCGAAATGCGATGAC... Gene: Pjdr2_4149: GCN5-related N-acetyltransferase	GCN5-related N-acetyltransferase

CRON 4.
ilvB	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU28310: Acetolactate synthase large subunit (EC 2.2.1.6)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_025370: Acetolactate synthase large subunit (EC 2.2.1.6)	Bacillus pumilus SAFR-032 Gene: BPUM_2472: Acetolactate synthase large subunit (EC 2.2.1.6)	Bacillus licheniformis DSM 13 Gene: BLi02961: Acetolactate synthase large subunit (EC 2.2.1.6)	Anoxybacillus flavithermus WK1 Gene: Aflv_0591: Acetolactate synthase large subunit (EC 2.2.1.6)	Geobacillus kaustophilus HTA426 Gene: GK2661: Acetolactate synthase large subunit (EC 2.2.1.6)	Bacillus cereus ATCC 14579 Gene: BC1777: Acetolactate synthase large subunit (EC 2.2.1.6)	Bacillus halodurans C-125 Gene: BH3061: Acetolactate synthase large subunit (EC 2.2.1.6)	Bacillus clausii KSM-K16 Gene: ABC2645: Acetolactate synthase large subunit (EC 2.2.1.6)	* Oceanobacillus iheyensis HTE831 Site: position = -384 score = 63.67 sequence = CGTTAATTCGTTGAC... Gene: OB2623: Acetolactate synthase large subunit (EC 2.2.1.6)	3 Paenibacillus sp. JDR-2 Gene: Pjdr2_2907: Acetolactate synthase large subunit (EC 2.2.1.6) Gene: Pjdr2_1302: Acetolactate synthase large subunit (EC 2.2.1.6) Gene: Pjdr2_4086: Acetolactate synthase large subunit (EC 2.2.1.6)	Acetolactate synthase large subunit (EC 2.2.1.6)
ilvH	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU28300: Acetolactate synthase small subunit (EC 2.2.1.6)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_025360: Acetolactate synthase small subunit (EC 2.2.1.6)	Bacillus pumilus SAFR-032 Gene: BPUM_2471: Acetolactate synthase small subunit (EC 2.2.1.6)	Bacillus licheniformis DSM 13 Gene: BLi02960: Acetolactate synthase small subunit (EC 2.2.1.6)	Anoxybacillus flavithermus WK1 Gene: Aflv_0592: Acetolactate synthase small subunit (EC 2.2.1.6)	Geobacillus kaustophilus HTA426 Gene: GK2660: Acetolactate synthase small subunit (EC 2.2.1.6)	Bacillus cereus ATCC 14579 Gene: BC1398: Acetolactate synthase small subunit (EC 2.2.1.6)	Bacillus halodurans C-125 Gene: BH3060: Acetolactate synthase small subunit (EC 2.2.1.6)	Bacillus clausii KSM-K16 Gene: ABC2644: Acetolactate synthase small subunit (EC 2.2.1.6)	Oceanobacillus iheyensis HTE831 Gene: OB2622: Acetolactate synthase small subunit (EC 2.2.1.6)	2 Paenibacillus sp. JDR-2 Gene: Pjdr2_2908: Acetolactate synthase small subunit (EC 2.2.1.6) Gene: Pjdr2_1303: Acetolactate synthase small subunit (EC 2.2.1.6)	Acetolactate synthase small subunit (EC 2.2.1.6)
ilvC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU28290: Ketol-acid reductoisomerase (EC 1.1.1.86)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_025350: Ketol-acid reductoisomerase (EC 1.1.1.86)	Bacillus pumilus SAFR-032 Gene: BPUM_2470: Ketol-acid reductoisomerase (EC 1.1.1.86)	Bacillus licheniformis DSM 13 Gene: BLi02959: Ketol-acid reductoisomerase (EC 1.1.1.86)	Anoxybacillus flavithermus WK1 Gene: Aflv_0593: Ketol-acid reductoisomerase (EC 1.1.1.86)	Geobacillus kaustophilus HTA426 Gene: GK2659: Ketol-acid reductoisomerase (EC 1.1.1.86)	2 Bacillus cereus ATCC 14579 Gene: BC1399: Ketol-acid reductoisomerase (EC 1.1.1.86) Gene: BC1779: Ketol-acid reductoisomerase (EC 1.1.1.86)	Bacillus halodurans C-125 Gene: BH3059: Ketol-acid reductoisomerase (EC 1.1.1.86)	Bacillus clausii KSM-K16 Gene: ABC2643: Ketol-acid reductoisomerase (EC 1.1.1.86)	Oceanobacillus iheyensis HTE831 Gene: OB2621: Ketol-acid reductoisomerase (EC 1.1.1.86)	Paenibacillus sp. JDR-2 Gene: Pjdr2_1304: Ketol-acid reductoisomerase (EC 1.1.1.86)	Ketol-acid reductoisomerase (EC 1.1.1.86)
leuA	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU28280: 2-isopropylmalate synthase (EC 2.3.3.13)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_025340: 2-isopropylmalate synthase (EC 2.3.3.13)	Bacillus pumilus SAFR-032 Gene: BPUM_2469: 2-isopropylmalate synthase (EC 2.3.3.13)	Bacillus licheniformis DSM 13 Gene: BLi02958: 2-isopropylmalate synthase (EC 2.3.3.13)	Anoxybacillus flavithermus WK1 Gene: Aflv_0594: 2-isopropylmalate synthase (EC 2.3.3.13)	Geobacillus kaustophilus HTA426 Gene: GK2658: 2-isopropylmalate synthase (EC 2.3.3.13)	Bacillus cereus ATCC 14579 Gene: BC1400: 2-isopropylmalate synthase (EC 2.3.3.13)	Bacillus halodurans C-125 Gene: BH3058: 2-isopropylmalate synthase (EC 2.3.3.13)	Bacillus clausii KSM-K16 Gene: ABC2642: 2-isopropylmalate synthase (EC 2.3.3.13)	Oceanobacillus iheyensis HTE831 Gene: OB2620: 2-isopropylmalate synthase (EC 2.3.3.13)	2 Paenibacillus sp. JDR-2 Gene: Pjdr2_1305: 2-isopropylmalate synthase (EC 2.3.3.13) Gene: Pjdr2_1026: 2-isopropylmalate synthase (EC 2.3.3.13)	2-isopropylmalate synthase (EC 2.3.3.13)
leuB	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU28270: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_025330: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Bacillus pumilus SAFR-032 Gene: BPUM_2468: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Bacillus licheniformis DSM 13 Gene: BLi02957: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Anoxybacillus flavithermus WK1 Gene: Aflv_0595: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Geobacillus kaustophilus HTA426 Gene: GK2657: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Bacillus cereus ATCC 14579 Gene: BC1401: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Bacillus halodurans C-125 Gene: BH3057: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Bacillus clausii KSM-K16 Gene: ABC2641: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Oceanobacillus iheyensis HTE831 Gene: OB2619: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Paenibacillus sp. JDR-2	3-isopropylmalate dehydrogenase (EC 1.1.1.85)
leuC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU28260: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_025320: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Bacillus pumilus SAFR-032 Gene: BPUM_2467: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Bacillus licheniformis DSM 13 Gene: BLi02956: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Anoxybacillus flavithermus WK1 Gene: Aflv_0596: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Geobacillus kaustophilus HTA426 Gene: GK2656: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Bacillus cereus ATCC 14579 Gene: BC1402: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Bacillus halodurans C-125 Gene: BH3056: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Bacillus clausii KSM-K16 Gene: ABC2640: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Oceanobacillus iheyensis HTE831 Gene: OB2618: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Paenibacillus sp. JDR-2 Gene: Pjdr2_2473: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU28250: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_025310: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Bacillus pumilus SAFR-032 Gene: BPUM_2466: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Bacillus licheniformis DSM 13 Gene: BLi02955: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Anoxybacillus flavithermus WK1 Gene: Aflv_0597: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Geobacillus kaustophilus HTA426 Gene: GK2655: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Bacillus cereus ATCC 14579 Gene: BC1403: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Bacillus halodurans C-125 Gene: BH3055: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Bacillus clausii KSM-K16 Gene: ABC2639: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Oceanobacillus iheyensis HTE831 Gene: OB2617: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Paenibacillus sp. JDR-2 Gene: Pjdr2_2474: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
ilvA	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_1393: Threonine dehydratase (EC 4.3.1.19)	Geobacillus kaustophilus HTA426 Gene: GK1591: Threonine dehydratase (EC 4.3.1.19)	2 Bacillus cereus ATCC 14579 Gene: BC2400: Threonine dehydratase (EC 4.3.1.19) Gene: BC1781: Threonine dehydratase (EC 4.3.1.19)	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB2616: Threonine dehydratase (EC 4.3.1.19)	Paenibacillus sp. JDR-2	Threonine dehydratase (EC 4.3.1.19)
ilvE	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	* Bacillus cereus ATCC 14579 Site: position = -411 score = 97.28 sequence = AGAATGCGTAGAAGA... Gene: BC1776: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Branched-chain amino acid aminotransferase (EC 2.6.1.42)
ilvD	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU21870: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_020010: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Bacillus pumilus SAFR-032 Gene: BPUM_1922: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Bacillus licheniformis DSM 13 Gene: BLi02324: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Anoxybacillus flavithermus WK1 Gene: Aflv_1238: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Geobacillus kaustophilus HTA426 Gene: GK2046: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Bacillus cereus ATCC 14579 Gene: BC1780: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Bacillus halodurans C-125 Gene: BH3062: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Bacillus clausii KSM-K16 Gene: ABC2646: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_4335: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Dihydroxy-acid dehydratase (EC 4.2.1.9)

CRON 5.
ileS	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -278 score = 104.73 sequence = AAAAAACGGTTGAAA... Gene: BSU15430: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Bacillus amyloliquefaciens FZB42 Site: position = -280 score = 97.17 sequence = AAAAGACGATTGAAA... Gene: RBAM_015260: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Bacillus pumilus SAFR-032 Site: position = -290 score = 107.02 sequence = GATAAACGTTTGAAA... Gene: BPUM_1442: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Bacillus licheniformis DSM 13 Site: position = -280 score = 100.21 sequence = GAAAAACGTTTGAGA... Gene: BLi01762: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Anoxybacillus flavithermus WK1 Site: position = -262 score = 133.42 sequence = GCAAAAAACGATGAA... Gene: Aflv_1812: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Geobacillus kaustophilus HTA426 Site: position = -273 score = 110.63 sequence = CATCGACGATGAAAG... Gene: GK1136: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Bacillus cereus ATCC 14579 Site: position = -296 score = 120.33 sequence = AAGAAAAACGAAGAT... Gene: BC3895: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Bacillus halodurans C-125 Site: position = -330 score = 104.57 sequence = ACAATGGACGATGAG... Gene: BH2545: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Bacillus clausii KSM-K16 Site: position = -291 score = 88.65 sequence = GTTAAAAACAAGGAT... Gene: ABC2342: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Oceanobacillus iheyensis HTE831 Site: position = -262 score = 127.95 sequence = TAAAAGCAATGATAG... Gene: OB1484: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	Paenibacillus sp. JDR-2	Isoleucyl-tRNA synthetase (EC 6.1.1.5)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog T-box(Ile) - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --