Regulog TPP - Enterobacteriales
Regulator type: | RNA regulatory element |
Name: | TPP |
RFAM: | RF00059 |
Regulation mode: | |
Biological process: | Thiamine biosynthesis |
Effector: | Thiamine pyrophosphate |
Phylum: | Proteobacteria |

Member of regulog collections
- By taxonomy - Enterobacteriales
- By RNA motif - TPP
- By effector - Thiamine pyrophosphate
- By pathway - Thiamine biosynthesis
Genome | Genes | Operons |
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Citrobacter koseri ATCC BAA-895 | 11 | 3 |
Edwardsiella tarda EIB202 | 7 | 3 |
Enterobacter sp. 638 | 11 | 3 |
Erwinia amylovora ATCC 49946 | 11 | 4 |
Erwinia carotovora subsp. atroseptica SCRI1043 | 11 | 3 |
Escherichia coli str. K-12 substr. MG1655 | 11 | 3 |
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 | 14 | 4 |
Photorhabdus luminescens subsp. laumondii TTO1 | 9 | 2 |
Proteus mirabilis HI4320 | 10 | 3 |
Salmonella typhimurium LT2 | 11 | 3 |
Serratia proteamaculans 568 | 15 | 4 |
Yersinia pestis KIM | 9 | 3 |
Genes | Function | ||||||||||||
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CRON 1. | |||||||||||||
tenA |
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Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -169 score = 67.85 sequence = GCGCTACCGAGGGGT... Gene: KPN_01799: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
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Serratia proteamaculans 568 Site: position = -164 score = 71.75 sequence = GCTCCTCCGAGGGGT... Gene: Spro_3122: 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
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4-amino-5-aminomethyl-2-methylpyrimidine hydrolase TenA |
thiZ |
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Gene: KPN_01800: Hydroxymethylpyrimidine ABC transporter, ATPase component |
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Gene: Spro_3123: Hydroxymethylpyrimidine ABC transporter, ATPase component |
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Hydroxymethylpyrimidine ABC transporter, ATPase component |
thiX |
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Gene: KPN_01801: Hydroxymethylpyrimidine ABC transporter, transmembrane component |
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Gene: Spro_3124: Hydroxymethylpyrimidine ABC transporter, transmembrane component |
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Hydroxymethylpyrimidine ABC transporter, transmembrane component |
thiY |
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Gene: Spro_3125: Hydroxymethylpyrimidine ABC transporter, substrate-binding component |
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Hydroxymethylpyrimidine ABC transporter, substrate-binding component |
CRON 2. | |||||||||||||
thiB |
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Citrobacter koseri ATCC BAA-895 Site: position = -140 score = 61.68 sequence = CGTCCTCAACGGGGT... Gene: CKO_03314: Thiamin ABC transporter, substrate-binding component |
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Edwardsiella tarda EIB202 Site: position = -141 score = 66.11 sequence = CGCCGTCTCAACGGG... Gene: ETAE_0610: Thiamin ABC transporter, substrate-binding component |
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Enterobacter sp. 638 Site: position = -133 score = 61.42 sequence = GCTGTTCTCAACGGG... Gene: Ent638_0615: Thiamin ABC transporter, substrate-binding component |
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Erwinia amylovora ATCC 49946 Site: position = -135 score = 49.28 sequence = CGCCGGATCAATGGC... Gene: EAM_0677: Thiamin ABC transporter, substrate-binding component |
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Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -176 score = 70.13 sequence = CGTTCTCAACGGGGT... Gene: ECA3844: Thiamin ABC transporter, substrate-binding component |
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Escherichia coli str. K-12 substr. MG1655 Site: position = -131 score = 60.86 sequence = GCCGTTCTCAACGGG... Gene: b0068: Thiamin ABC transporter, substrate-binding component |
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Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -253 score = 49.63 sequence = GCCGTTCTCAACGGG... Gene: KPN_00067: Thiamin ABC transporter, substrate-binding component |
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Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -178 score = 65.55 sequence = CGCCATCTCAACGGG... Gene: plu0619: Thiamin ABC transporter, substrate-binding component |
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Proteus mirabilis HI4320 Site: position = -156 score = 68.28 sequence = ATGTCTCAACGGGGT... Gene: PMI2322: Thiamin ABC transporter, substrate-binding component |
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Salmonella typhimurium LT2 Site: position = -132 score = 64.52 sequence = GCCGAACTCAACGGG... Gene: STM0108: Thiamin ABC transporter, substrate-binding component |
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Serratia proteamaculans 568 Site: position = -165 score = 63.65 sequence = CGCCGTCTCAACGGG... Gene: Spro_0737: Thiamin ABC transporter, substrate-binding component |
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Yersinia pestis KIM Site: position = -166 score = 39.1 sequence = ACCACCTAACCGCCG... Gene: y3651: Thiamin ABC transporter, substrate-binding component |
Thiamin ABC transporter, substrate-binding component |
thiP |
Gene: CKO_03315: Thiamin ABC transporter, transmembrane component |
Gene: ETAE_0609: Thiamin ABC transporter, transmembrane component |
Gene: Ent638_0614: Thiamin ABC transporter, transmembrane component |
Gene: EAM_0676: Thiamin ABC transporter, transmembrane component |
Gene: ECA3845: Thiamin ABC transporter, transmembrane component |
Gene: b0067: Thiamin ABC transporter, transmembrane component |
Gene: KPN_00066: Thiamin ABC transporter, transmembrane component |
Gene: plu0618: Thiamin ABC transporter, transmembrane component |
Gene: PMI2323: Thiamin ABC transporter, transmembrane component |
Gene: STM0107: Thiamin ABC transporter, transmembrane component |
Gene: Spro_0736: Thiamin ABC transporter, transmembrane component |
Gene: y3652: Thiamin ABC transporter, transmembrane component |
Thiamin ABC transporter, transmembrane component |
thiQ |
Gene: CKO_03316: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: ETAE_0608: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: Ent638_0613: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: EAM_0675: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: ECA3846: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: b0066: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: KPN_00065: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: plu0617: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: PMI2324: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: STM0106: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: Spro_0735: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Gene: y3653: Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
Thiamin ABC transporter, ATPase component / Thiamine transport ATP-binding protein thiQ |
CRON 3. | |||||||||||||
thiM |
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Citrobacter koseri ATCC BAA-895 Site: position = -128 score = 68.4 sequence = TCAACGACTCGGGGT... Gene: CKO_00680: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Edwardsiella tarda EIB202 Site: position = -130 score = 69.55 sequence = CAACTGACTCGGGGT... Gene: ETAE_1058: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Enterobacter sp. 638 Site: position = -133 score = 70.12 sequence = GTAATTTGACTCGGG... Gene: Ent638_2711: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Erwinia amylovora ATCC 49946 Site: position = -137 score = 68.36 sequence = GACCAATGACTCGGG... Gene: EAM_2193: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -133 score = 66.99 sequence = AGTACATGACTCGGG... Gene: ECA3197: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Escherichia coli str. K-12 substr. MG1655 Site: position = -132 score = 65.83 sequence = ACCAAACGACTCGGG... Gene: b2104: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -133 score = 66.58 sequence = CTATTTTGACTCGGG... Gene: KPN_02551: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Salmonella typhimurium LT2 Site: position = -129 score = 64.07 sequence = GCTTGACGACTCGGG... Gene: STM2147: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Serratia proteamaculans 568 Site: position = -129 score = 65.11 sequence = ACCGTCTGACTCGGG... Gene: Spro_3578: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Hydroxyethylthiazole kinase (EC 2.7.1.50) |
thiD |
Gene: CKO_00681: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: ETAE_1059: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: Ent638_2710: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: EAM_2192: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: ECA3196: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: b2103: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: KPN_02550: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: plu2782: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Proteus mirabilis HI4320 Site: position = -140 score = 70.01 sequence = AAGCTTTGGCTCGGG... Gene: PMI1593: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: STM2146: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: Spro_3577: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Yersinia pestis KIM Site: position = -227 score = 64.46 sequence = ATTCTGACTCGGGGT... Gene: y1373: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
CRON 4. | |||||||||||||
thiC |
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Citrobacter koseri ATCC BAA-895 Site: position = -194 score = 72.03 sequence = ACATCTTGTCGGAGT... Gene: CKO_02992: Phosphomethylpyrimidine synthase ThiC |
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Edwardsiella tarda EIB202 Site: position = -227 score = 71.68 sequence = CGCTATCTTGTCGGA... Gene: ETAE_0178: Phosphomethylpyrimidine synthase ThiC |
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Enterobacter sp. 638 Site: position = -190 score = 74.35 sequence = AAATTTCTTGTCGGA... Gene: Ent638_0207: Phosphomethylpyrimidine synthase ThiC |
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Erwinia amylovora ATCC 49946 Site: position = -191 score = 76.37 sequence = CATTATCTTGTCGGA... Gene: EAM_0240: Phosphomethylpyrimidine synthase ThiC |
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Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -253 score = 69.11 sequence = GCAAATCTTGTCGGA... Gene: ECA0232: Phosphomethylpyrimidine synthase ThiC |
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Escherichia coli str. K-12 substr. MG1655 Site: position = -182 score = 75.62 sequence = TAATTTCTTGTCGGA... Gene: b3994: Phosphomethylpyrimidine synthase ThiC |
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Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -211 score = 74.31 sequence = TTTCATCTTGTCGGA... Gene: KPN_04376: Phosphomethylpyrimidine synthase ThiC |
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Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -245 score = 72.96 sequence = TACTTTCTTGTCGGA... Gene: plu0486: Phosphomethylpyrimidine synthase ThiC |
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Proteus mirabilis HI4320 Site: position = -253 score = 71.06 sequence = CATTCTTGTCGGAGT... Gene: PMI2777: Phosphomethylpyrimidine synthase ThiC |
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Salmonella typhimurium LT2 Site: position = -313 score = 55.54 sequence = GGTTATCTTGTCGGA... Gene: STM4164: Phosphomethylpyrimidine synthase ThiC |
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Serratia proteamaculans 568 Site: position = -241 score = 71.5 sequence = GGGCATCTTGTCGGA... Gene: Spro_0284: Phosphomethylpyrimidine synthase ThiC |
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Yersinia pestis KIM Site: position = -260 score = 71.46 sequence = AAGGCTCTTGTCGGA... Gene: y0491: Phosphomethylpyrimidine synthase ThiC |
Phosphomethylpyrimidine synthase ThiC |
thiE |
Gene: CKO_02993: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: ETAE_0177: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: Ent638_0206: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: EAM_0239: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: ECA0231: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: b3993: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: KPN_04375: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: plu0485: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: PMI2778: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: STM4163: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: Spro_0283: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: y0490: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
thiF |
Gene: CKO_02994: Sulfur carrier protein adenylyltransferase ThiF |
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Gene: Ent638_0205: Sulfur carrier protein adenylyltransferase ThiF |
Gene: EAM_P117: Sulfur carrier protein adenylyltransferase ThiF |
Gene: ECA0230: Sulfur carrier protein adenylyltransferase ThiF |
Gene: b3992: Sulfur carrier protein adenylyltransferase ThiF |
Gene: KPN_04374: Sulfur carrier protein adenylyltransferase ThiF |
Gene: plu0484: Sulfur carrier protein adenylyltransferase ThiF |
Gene: PMI2779: Sulfur carrier protein adenylyltransferase ThiF |
Gene: STM4162: Sulfur carrier protein adenylyltransferase ThiF |
Gene: Spro_0282: Sulfur carrier protein adenylyltransferase ThiF |
Gene: y0489: Sulfur carrier protein adenylyltransferase ThiF |
Sulfur carrier protein adenylyltransferase ThiF |
thiS |
Gene: CKO_02995: Sulfur carrier protein ThiS |
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Gene: Ent638_0204: Sulfur carrier protein ThiS |
Gene: EAM_P119: Sulfur carrier protein ThiS |
Gene: ECA0229A: Sulfur carrier protein ThiS |
Gene: b4407: Sulfur carrier protein ThiS |
Gene: KPN_04373: Sulfur carrier protein ThiS |
Gene: plu0483: Sulfur carrier protein ThiS |
Gene: PMI2780: Sulfur carrier protein ThiS |
Gene: STM4161: Sulfur carrier protein ThiS |
Gene: Spro_0281: Sulfur carrier protein ThiS |
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Sulfur carrier protein ThiS |
thiG |
Gene: CKO_02996: Thiazole synthase |
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Gene: Ent638_0203: Thiazole synthase |
Gene: EAM_P118: Thiazole synthase |
Gene: ECA0229: Thiazole synthase |
Gene: b3991: Thiazole synthase |
Gene: KPN_04372: Thiazole synthase |
Gene: plu0482: Thiazole synthase |
Gene: PMI2781: Thiazole synthase |
Gene: STM4160: Thiazole synthase |
Gene: Spro_0280: Thiazole synthase |
Gene: y0488: Thiazole synthase |
Thiazole synthase |
thiH |
Gene: CKO_02997: 2-iminoacetate synthase (EC 1.3.99.n2) |
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Gene: Ent638_0202: 2-iminoacetate synthase (EC 1.3.99.n2) |
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Gene: ECA0228: 2-iminoacetate synthase (EC 1.3.99.n2) |
Gene: b3990: 2-iminoacetate synthase (EC 1.3.99.n2) |
Gene: KPN_04371: 2-iminoacetate synthase (EC 1.3.99.n2) |
Gene: plu0481: 2-iminoacetate synthase (EC 1.3.99.n2) |
Gene: PMI2782: 2-iminoacetate synthase (EC 1.3.99.n2) |
Gene: STM4159: 2-iminoacetate synthase (EC 1.3.99.n2) |
Gene: Spro_0279: 2-iminoacetate synthase (EC 1.3.99.n2) |
Gene: y0487: 2-iminoacetate synthase (EC 1.3.99.n2) |
2-iminoacetate synthase (EC 1.3.99.n2) |
thiO |
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Erwinia amylovora ATCC 49946 Site: position = -147 score = 62.93 sequence = TAGTTCCTGTCAGGG... Gene: EAM_P120: Glycine oxidase ThiO (EC 1.4.3.19) |
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Glycine oxidase ThiO (EC 1.4.3.19) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |