Regulog IolR1 - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	Inositol utilization
Effector:
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 13 sites [see more]

Member of regulog collections

By taxonomy - Bacillales
By TF family - LacI
By pathway - Inositol utilization

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	2	2
Bacillus amyloliquefaciens FZB42
Bacillus pumilus SAFR-032
Bacillus licheniformis DSM 13	1	1
Anoxybacillus flavithermus WK1
Geobacillus kaustophilus HTA426	13	2
Bacillus cereus ATCC 14579
Bacillus halodurans C-125	6	2
Bacillus clausii KSM-K16
Oceanobacillus iheyensis HTE831
Paenibacillus sp. JDR-2	7	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
BH2322	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	* Geobacillus kaustophilus HTA426 Site: position = -208 score = 5.31641 sequence = GGAAAGCGCTTGCC Gene: GK1894: Inositol transport system ATP-binding protein	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2322: Inositol transport system ATP-binding protein	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Inositol transport system ATP-binding protein
BH2321	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1893: Inositol transport system permease protein	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2321: Inositol transport system permease protein	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Inositol transport system permease protein
iolI	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU39680: Inosose isomerase (EC 5.3.99.-)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_036700: Inosose isomerase (EC 5.3.99.-)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi04243: Inosose isomerase (EC 5.3.99.-)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1892: Inosose isomerase (EC 5.3.99.-)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2315: Inosose isomerase (EC 5.3.99.-)	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Inosose isomerase (EC 5.3.99.-)
iolD	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU39730: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	Bacillus amyloliquefaciens FZB42 Gene: RBAM_036750: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi04248: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1891: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2318: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	Bacillus clausii KSM-K16 Gene: ABC0425: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	Oceanobacillus iheyensis HTE831	* Paenibacillus sp. JDR-2 Site: position = -108 score = 4.97551 sequence = GTTAAGCGCTTAAC Gene: Pjdr2_1948: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase
iolE	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1890: Inosose dehydratase (EC 4.2.1.44)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_1949: Inosose dehydratase (EC 4.2.1.44)	Inosose dehydratase (EC 4.2.1.44)
iolB	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU39750: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_036770: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi04250: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1889: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2320: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Bacillus clausii KSM-K16 Gene: ABC0423: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_1953: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	5-deoxy-glucuronate isomerase (EC 5.3.1.-)
iolC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU39740: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_036760: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi04249: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1888: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2319: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Bacillus clausii KSM-K16 Gene: ABC0424: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_1950: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	5-keto-2-deoxygluconokinase (EC 2.7.1.92)
iolA	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU39760: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_036780: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi04251: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1887: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2312: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Bacillus clausii KSM-K16 Gene: ABC0422: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_1951: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
iolJ	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU39670: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_036690: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi04242: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1886: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2314: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Bacillus clausii KSM-K16 Gene: ABC0428: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
yrbE	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -38 score = 4.63434 sequence = ATAAAGCGCTTTCG Gene: BSU27770: Predicted inositol derivative dehydrogenase	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2221: Predicted inositol derivative dehydrogenase	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_1952: Predicted inositol derivative dehydrogenase	Predicted inositol derivative dehydrogenase
iolR1	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU10840: Transcriptional regulator of inositol utilization, LacI family	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi01180: Transcriptional regulator of inositol utilization, LacI family	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1901: Transcriptional regulator of inositol utilization, LacI family	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2219: Transcriptional regulator of inositol utilization, LacI family	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_1954: Transcriptional regulator of inositol utilization, LacI family	Transcriptional regulator of inositol utilization, LacI family
BH2222	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi02212: Na+:myo-inositol cotransporter	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -118 score = 5.3419 sequence = GGAAAGCGCTTACT Site: position = -39 score = 4.97551 sequence = GTTAAGCGCTTAAC Gene: BH2222: Na+:myo-inositol cotransporter	Bacillus clausii KSM-K16 Gene: ABC0430: Na+:myo-inositol cotransporter	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Na+:myo-inositol cotransporter
BH0710	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1898: Predicted inositol derivative dehydrogenase	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2220: Predicted inositol derivative dehydrogenase	Bacillus clausii KSM-K16 Gene: ABC0577: Predicted inositol derivative dehydrogenase	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_1117: Predicted inositol derivative dehydrogenase	Predicted inositol derivative dehydrogenase
BC4668	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	* Geobacillus kaustophilus HTA426 Site: position = -44 score = 4.88717 sequence = AGAAAGCGCTTCCC Site: position = -129 score = 5.14294 sequence = GGAAAGCGCTTGCT Gene: GK1899: Predicted inositol derivative dehydrogenase	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Predicted inositol derivative dehydrogenase
iolX	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -112 score = 4.54116 sequence = AGAAAGCGCTTGCG Site: position = -53 score = 5.01559 sequence = AGAAAACGCTTTCT Gene: BSU10850: Scyllo-inositol 2-dehydrogenase like (EC 1.1.1.-)	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -59 score = 4.96947 sequence = AGCAAGCGCTTTCT Site: position = -137 score = 4.61934 sequence = AGCAAGCGCTTGAC Site: position = -38 score = 4.63434 sequence = ATAAAGCGCTTTCA Gene: BLi01181: Scyllo-inositol 2-dehydrogenase like (EC 1.1.1.-)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1897: Scyllo-inositol 2-dehydrogenase like (EC 1.1.1.-)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC0429: Scyllo-inositol 2-dehydrogenase like (EC 1.1.1.-)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Scyllo-inositol 2-dehydrogenase like (EC 1.1.1.-)
BH3901	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK1896: Inositol transport system sugar-binding protein	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -127 score = 5.12669 sequence = AGAAAGCGCTTAAC Gene: BH3901: Inositol transport system sugar-binding protein	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Inositol transport system sugar-binding protein
BH3900	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH3900: Methyl-accepting chemotaxis protein	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Methyl-accepting chemotaxis protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog IolR1 - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --