Regulog ComA - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	LuxR
Regulation mode:	activator
Biological process:	Competence
Effector:	ComP, sensor histidine kinase (ComX)
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 16 sites [see more]

Member of regulog collections

By taxonomy - Bacillales
By TF family - LuxR
By effector - ComP, sensor histidine kinase (ComX)
By pathway - Competence

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	13	7
Bacillus amyloliquefaciens FZB42	8	4
Bacillus pumilus SAFR-032	7	2
Bacillus licheniformis DSM 13	5	2
Anoxybacillus flavithermus WK1
Geobacillus kaustophilus HTA426
Bacillus cereus ATCC 14579
Bacillus halodurans C-125
Bacillus clausii KSM-K16
Oceanobacillus iheyensis HTE831
Paenibacillus sp. JDR-2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
degQ	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -145 score = 8.09313 sequence = TTGCGGTGTCACGCAG-(16)-TTTCGG Gene: BSU31720: Degradation enzyme regulation protein DegQ	* Bacillus amyloliquefaciens FZB42 Site: position = -146 score = 8.09313 sequence = TTGCGGTGTCACGCAG-(17)-TTTCGG Gene: RBAM_028800: Degradation enzyme regulation protein DegQ	* Bacillus pumilus SAFR-032 Site: position = -145 score = 8.41765 sequence = TTGCGGTATCACGCAC-(16)-TTTCGG Gene: BPUM_2841: Degradation enzyme regulation protein DegQ	* Bacillus licheniformis DSM 13 Site: position = -143 score = 8.40522 sequence = TTGCGGTGTAACGCAT-(16)-TTTCGG Gene: BLi03360: Degradation enzyme regulation protein DegQ	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Degradation enzyme regulation protein DegQ

CRON 2.
rapC	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -104 score = 7.2488 sequence = TTGCGTGCTCCCGAAA-(16)-TTTCGG Gene: BSU03770: Response regulator aspartate phosphatase	* Bacillus amyloliquefaciens FZB42 Site: position = -103 score = 7.1194 sequence = TTGCGCTCTGCCGAAA-(15)-TTTCGG Gene: RBAM_004010: Response regulator aspartate phosphatase	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Response regulator aspartate phosphatase
phrC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU03780: Secreted regulator of the activity of phosphatase RapC and competence and sporulation stimulating factor (CSF)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_004020: Secreted regulator of the activity of phosphatase RapC and competence and sporulation stimulating factor (CSF)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Secreted regulator of the activity of phosphatase RapC and competence and sporulation stimulating factor (CSF)

CRON 3.
rapA	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -106 score = 8.06221 sequence = TTGCGGTTAGCCGAAA-(8)-TTGCGG Gene: BSU12430: Response regulator aspartate phosphatase	* Bacillus amyloliquefaciens FZB42 Site: position = -112 score = 7.29514 sequence = TTGCGGATATCCGAAA-(8)-TTGCGG Gene: RBAM_012450: Response regulator aspartate phosphatase	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Response regulator aspartate phosphatase
phrA	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU12440: Secreted inhibitor of the activity of phosphatase RapA	Bacillus amyloliquefaciens FZB42 Gene: RBAM_012460: Secreted inhibitor of the activity of phosphatase RapA	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Secreted inhibitor of the activity of phosphatase RapA

CRON 4.
rapF	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -106 score = 8.37795 sequence = ATGCGGTGTAACGAAA-(7)-TTGCGG Gene: BSU37460: Response regulator aspartate phosphatase	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034530: Response regulator aspartate phosphatase	Bacillus pumilus SAFR-032 Gene: BPUM_2152: Response regulator aspartate phosphatase	Bacillus licheniformis DSM 13 Gene: BLi01063: Response regulator aspartate phosphatase	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Response regulator aspartate phosphatase
phrF	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37470: Secreted regulator of the activity of phosphatase RapF	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034540: Secreted regulator of the activity of phosphatase RapF	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Secreted regulator of the activity of phosphatase RapF

CRON 5.
pel	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -124 score = 7.95263 sequence = TTGCAGAATGCCGCAA-(16)-TTTCGG Gene: BSU07560: Pectate lyase precursor (EC 4.2.2.2)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_007720: Pectate lyase precursor (EC 4.2.2.2)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi01404: Pectate lyase precursor (EC 4.2.2.2)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Pectate lyase precursor (EC 4.2.2.2)

CRON 6.
rapE	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -108 score = 7.90335 sequence = TTGCGGTCTCACCGAA-(8)-TTGCGG Gene: BSU25830: Response regulator aspartate phosphatase	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi02480: Response regulator aspartate phosphatase	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Response regulator aspartate phosphatase
phrE	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU25840: Regulator of the activity of phosphatase RapE	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Regulator of the activity of phosphatase RapE

CRON 7.
srfAC	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -364 score = 9.51002 sequence = TTTCGGCATCCCGCAT-(17)-TTTCGG Gene: BSU03480: Surfactin synthetase subunit 1	* Bacillus amyloliquefaciens FZB42 Site: position = -337 score = 8.98174 sequence = TTTCGGTGTGCCGCAT-(17)-TTTCGG Gene: RBAM_003650: Surfactin synthetase subunit 1	* Bacillus pumilus SAFR-032 Site: position = -330 score = 8.8041 sequence = ATTCGGCATAACGCAT-(17)-TTTCGG Gene: BPUM_0319: Surfactin synthetase subunit 1	* Bacillus licheniformis DSM 13 Site: position = -372 score = 9.26255 sequence = ATTCGGTATCCCGCAT-(17)-TTTCGG Site: position = -405 score = 8.20459 sequence = TTTCGGGATCGCGCAT-(17)-ATTCGG Gene: BLi00401: Surfactin synthetase subunit 1	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Surfactin synthetase subunit 1
srfAB	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU03490: Surfactin synthetase subunit 2	Bacillus amyloliquefaciens FZB42 Gene: RBAM_003660: Surfactin synthetase subunit 2	Bacillus pumilus SAFR-032 Gene: BPUM_0320: Surfactin synthetase subunit 2	Bacillus licheniformis DSM 13 Gene: BLi00402: Surfactin synthetase subunit 2	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Surfactin synthetase subunit 2
srfAC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU03510: Surfactin synthetase subunit 3	Bacillus amyloliquefaciens FZB42 Gene: RBAM_003680: Surfactin synthetase subunit 3	Bacillus pumilus SAFR-032 Gene: BPUM_0321: Surfactin synthetase subunit 3	Bacillus licheniformis DSM 13 Gene: BLi00403: Surfactin synthetase subunit 3	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Surfactin synthetase subunit 3
BPUM_0322	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_0322: Nonribosomal peptide synthetase subunit	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Nonribosomal peptide synthetase subunit
BPUM_0323	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_0323: Nonribosomal peptide synthetase subunit	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Nonribosomal peptide synthetase subunit
srfAD	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU03520: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_003690: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)	Bacillus pumilus SAFR-032 Gene: BPUM_0324: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)	Bacillus licheniformis DSM 13 Gene: BLi00404: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Surfactin synthetase thioesterase subunit (EC 3.1.2.-)
comS	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU03500: Competence protein S	Bacillus amyloliquefaciens FZB42 Gene: RBAM_003670: Competence protein S	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Competence protein S

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog ComA - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --