Regulog CysL - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Sulfite reduction
Effector:	Sulfate; Sulfite; Thiosulfate
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 28 sites [see more]

Member of regulog collections

By taxonomy - Bacillales
By TF family - LysR
By effector - Sulfate
By effector - Sulfite
By effector - Thiosulfate
By pathway - Sulfite reduction

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	3	2
Bacillus amyloliquefaciens FZB42	3	2
Bacillus pumilus SAFR-032	3	2
Bacillus licheniformis DSM 13	3	2
Anoxybacillus flavithermus WK1	4	3
Geobacillus kaustophilus HTA426	3	2
Bacillus cereus ATCC 14579
Bacillus halodurans C-125	3	1
Bacillus clausii KSM-K16
Oceanobacillus iheyensis HTE831	11	2
Paenibacillus sp. JDR-2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
cysH	2 Bacillus subtilis subsp. subtilis str. 168 Gene: BSU10930: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) Gene: BSU15570: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_015400: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Bacillus pumilus SAFR-032 Gene: BPUM_1456: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	2 Bacillus licheniformis DSM 13 Gene: BLi02154: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) Gene: BLi01778: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Anoxybacillus flavithermus WK1 Gene: Aflv_0316: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Geobacillus kaustophilus HTA426 Gene: GK0416: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Bacillus cereus ATCC 14579 Gene: BC1421: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Bacillus halodurans C-125 Gene: BH1486: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Bacillus clausii KSM-K16 Gene: ABC0611: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	* Oceanobacillus iheyensis HTE831 Site: position = -248 score = 4.45064 sequence = ATTTATTTTATCAAT Site: position = -79 score = 4.07241 sequence = ATGAATTATATTCAT Gene: OB1652: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Paenibacillus sp. JDR-2 Gene: Pjdr2_5647: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)	Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
cysJ	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -116 score = 5.16597 sequence = ATTAGGATTCTTAAT Gene: BSU33440: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	* Bacillus amyloliquefaciens FZB42 Site: position = -143 score = 5.2447 sequence = ATTAGTAATCTTAAT Site: position = -115 score = 3.94138 sequence = ATTATATATTTTACT Gene: RBAM_030610: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	* Bacillus pumilus SAFR-032 Site: position = -137 score = 5.04043 sequence = ATTAGAAATCTTAAT Site: position = -109 score = 3.94 sequence = ATTATATATTTTACT Gene: BPUM_1777: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	* Bacillus licheniformis DSM 13 Site: position = -306 score = 5.23037 sequence = ATTAAaAATcTTAAT Site: position = -275 score = 4.47176 sequence = ATatATtTTAcTAAT Gene: BLi01302: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	* Anoxybacillus flavithermus WK1 Site: position = -118 score = 4.45743 sequence = ATAAAAAAAATAAAT Site: position = -87 score = 4.90698 sequence = ATTTATTTTACTAAT Gene: Aflv_1597: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	* Geobacillus kaustophilus HTA426 Site: position = -194 score = 4.92921 sequence = ATTAGAAATACTAAT Site: position = -163 score = 4.90698 sequence = ATTTATTTTACTAAT Gene: GK1409: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH0609: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	Bacillus clausii KSM-K16 Gene: ABC0618: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	Oceanobacillus iheyensis HTE831 Gene: OB1653: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	Paenibacillus sp. JDR-2 Gene: Pjdr2_1786: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)	Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)
cysI	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU33430: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_030600: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Bacillus pumilus SAFR-032 Gene: BPUM_1778: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Bacillus licheniformis DSM 13 Gene: BLi01303: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Anoxybacillus flavithermus WK1 Gene: Aflv_1596: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Geobacillus kaustophilus HTA426 Gene: GK1410: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH0610: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Bacillus clausii KSM-K16 Gene: ABC0619: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Oceanobacillus iheyensis HTE831 Gene: OB1654: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Paenibacillus sp. JDR-2 Gene: Pjdr2_1787: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)	Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)
ylnD	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU15610: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_1460: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Bacillus licheniformis DSM 13 Gene: BLi01782: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Anoxybacillus flavithermus WK1 Gene: Aflv_0312: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Geobacillus kaustophilus HTA426 Gene: GK0413: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Bacillus cereus ATCC 14579 Gene: BC1426: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB1655: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Paenibacillus sp. JDR-2 Gene: Pjdr2_5914: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
sirB	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU15620: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_1461: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Bacillus licheniformis DSM 13 Gene: BLi01783: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Anoxybacillus flavithermus WK1 Gene: Aflv_0311: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Geobacillus kaustophilus HTA426 Gene: GK0412: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Bacillus cereus ATCC 14579 Gene: BC1427: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC0616: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Oceanobacillus iheyensis HTE831 Gene: OB1656: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Paenibacillus sp. JDR-2	Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
sirC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU15630: Precorrin-2 dehydrogenase	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_1462: Precorrin-2 dehydrogenase	Bacillus licheniformis DSM 13 Gene: BLi01784: Precorrin-2 dehydrogenase	Anoxybacillus flavithermus WK1 Gene: Aflv_0310: Precorrin-2 dehydrogenase	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC1428: Precorrin-2 dehydrogenase	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB1657: Precorrin-2 dehydrogenase	Paenibacillus sp. JDR-2	Precorrin-2 dehydrogenase
yjjA	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU12230: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_012310: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Bacillus pumilus SAFR-032 Gene: BPUM_1801: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Bacillus licheniformis DSM 13 Gene: BLi02842: Uroporphyrinogen-III synthase (EC 4.2.1.75)	* Anoxybacillus flavithermus WK1 Site: position = -171 score = 4.11416 sequence = ATCAATAATGCTAAT Gene: Aflv_1473: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Geobacillus kaustophilus HTA426 Gene: GK1829: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH2162: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Bacillus clausii KSM-K16 Gene: ABC3411: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Oceanobacillus iheyensis HTE831 Gene: OB1658: Uroporphyrinogen-III synthase (EC 4.2.1.75)	Paenibacillus sp. JDR-2	Uroporphyrinogen-III synthase (EC 4.2.1.75)
sat	2 Bacillus subtilis subsp. subtilis str. 168 Gene: BSU10920: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) Gene: BSU15590: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_015420: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Bacillus pumilus SAFR-032 Gene: BPUM_1458: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Bacillus licheniformis DSM 13 Gene: BLi01780: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Anoxybacillus flavithermus WK1 Gene: Aflv_0314: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Geobacillus kaustophilus HTA426 Gene: GK0415: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Bacillus cereus ATCC 14579 Gene: BC1422: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	2 Bacillus halodurans C-125 Gene: BH1487: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) Gene: BH3386: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Bacillus clausii KSM-K16 Gene: ABC0612: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Oceanobacillus iheyensis HTE831 Gene: OB1659: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)	Paenibacillus sp. JDR-2	Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
BH3384	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -214 score = 4.75718 sequence = ATTTTTAATCTTAAT Gene: BH3384: Sodium/sulfate symporter	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB1660: Sodium/sulfate symporter	Paenibacillus sp. JDR-2	Sodium/sulfate symporter
cysC	2 Bacillus subtilis subsp. subtilis str. 168 Gene: BSU10910: Adenylylsulfate kinase (EC 2.7.1.25) Gene: BSU15600: Adenylylsulfate kinase (EC 2.7.1.25)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_015430: Adenylylsulfate kinase (EC 2.7.1.25)	Bacillus pumilus SAFR-032 Gene: BPUM_1459: Adenylylsulfate kinase (EC 2.7.1.25)	Bacillus licheniformis DSM 13 Gene: BLi01781: Adenylylsulfate kinase (EC 2.7.1.25)	Anoxybacillus flavithermus WK1 Gene: Aflv_0313: Adenylylsulfate kinase (EC 2.7.1.25)	Geobacillus kaustophilus HTA426 Gene: GK0414: Adenylylsulfate kinase (EC 2.7.1.25)	Bacillus cereus ATCC 14579 Gene: BC1423: Adenylylsulfate kinase (EC 2.7.1.25)	2 Bacillus halodurans C-125 Gene: BH1489: Adenylylsulfate kinase (EC 2.7.1.25) Gene: BH3385: Adenylylsulfate kinase (EC 2.7.1.25)	Bacillus clausii KSM-K16 Gene: ABC0614: Adenylylsulfate kinase (EC 2.7.1.25)	Oceanobacillus iheyensis HTE831 Gene: OB1661: Adenylylsulfate kinase (EC 2.7.1.25)	Paenibacillus sp. JDR-2 Gene: Pjdr2_4461: Adenylylsulfate kinase (EC 2.7.1.25)	Adenylylsulfate kinase (EC 2.7.1.25)

CRON 2.
cysL	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -53 score = 4.7001 sequence = ATAAAGAAAACTAAT Site: position = -31 score = 4.31813 sequence = ATATATTTCATTAAT Gene: BSU37650: Transcriptional regulator for sulfite reductase, LysR family	* Bacillus amyloliquefaciens FZB42 Site: position = -64 score = 4.47176 sequence = ATTAGTAAAATATAT Site: position = -33 score = 4.76492 sequence = ATTAGGAAAAATAAT Gene: RBAM_034830: Transcriptional regulator for sulfite reductase, LysR family	* Bacillus pumilus SAFR-032 Site: position = -28 score = 4.37465 sequence = ATTAAGATTTCTGAT Gene: BPUM_3611: Transcriptional regulator for sulfite reductase, LysR family	* Bacillus licheniformis DSM 13 Site: position = -61 score = 4.47176 sequence = ATTAGTAAAATATAT Site: position = -30 score = 5.23037 sequence = ATTAAGATTTTTAAT Gene: BLi01300: Transcriptional regulator for sulfite reductase, LysR family	* Anoxybacillus flavithermus WK1 Site: position = -61 score = 4.90698 sequence = ATTAGTAAAATAAAT Site: position = -30 score = 4.45743 sequence = ATTTATTTTTTTTAT Gene: Aflv_1598: Transcriptional regulator for sulfite reductase, LysR family	* Geobacillus kaustophilus HTA426 Site: position = -81 score = 4.90698 sequence = ATTAGTAAAATAAAT Site: position = -50 score = 4.92921 sequence = ATTAGTATTTCTAAT Gene: GK1408: Transcriptional regulator for sulfite reductase, LysR family	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	* Oceanobacillus iheyensis HTE831 Site: position = -55 score = 4.3941 sequence = ATAAATATATATAAT Site: position = -33 score = 4.65623 sequence = ATTAAAAAAGTTAAT Gene: OB3407: Transcriptional regulator for sulfite reductase, LysR family	Paenibacillus sp. JDR-2	Transcriptional regulator for sulfite reductase, LysR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog CysL - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --