Regulog MhqR - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	MarR
Regulation mode:	repressor
Biological process:	2-Methylhydroquinone and catechol resistance
Effector:
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 35 sites [see more]

Member of regulog collections

By taxonomy - Bacillales
By TF family - MarR
By pathway - 2-Methylhydroquinone and catechol resistance

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	7	4
Bacillus amyloliquefaciens FZB42	7	4
Bacillus pumilus SAFR-032	5	3
Bacillus licheniformis DSM 13	6	4
Anoxybacillus flavithermus WK1	3	1
Geobacillus kaustophilus HTA426	1	1
Bacillus cereus ATCC 14579	6	5
Bacillus halodurans C-125
Bacillus clausii KSM-K16	3	3
Oceanobacillus iheyensis HTE831	3	2
Paenibacillus sp. JDR-2	4	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
mhqR	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU13670: Transcriptional regulator of thiol stress resistance, MarR family	Bacillus amyloliquefaciens FZB42 Gene: RBAM_013430: Transcriptional regulator of thiol stress resistance, MarR family	Bacillus pumilus SAFR-032 Gene: BPUM_1258: Transcriptional regulator of thiol stress resistance, MarR family	2 Bacillus licheniformis DSM 13* Site: position = -37 score = 6.7661 sequence = TATCTCGAATTCGAGATA Gene: BLi02022: Transcriptional regulator of thiol stress resistance, MarR family Gene: BLi01522: Transcriptional regulator of thiol stress resistance, MarR family	* Anoxybacillus flavithermus WK1 Site: position = -22 score = 6.25276 sequence = TATCTTGAAATCAAGATA Gene: Aflv_1578: Transcriptional regulator of thiol stress resistance, MarR family	Geobacillus kaustophilus HTA426 Gene: GK0958: Transcriptional regulator of thiol stress resistance, MarR family	2 Bacillus cereus ATCC 14579* Site: position = -39 score = 6.3083 sequence = AATCTCGAATTCAAGATA Gene: BC3128: Transcriptional regulator of thiol stress resistance, MarR family Gene: BC1337: Transcriptional regulator of thiol stress resistance, MarR family	Bacillus halodurans C-125	* Bacillus clausii KSM-K16 Site: position = -30 score = 5.19661 sequence = AATTTCTAATTCGAGATG Gene: ABC0738: Transcriptional regulator of thiol stress resistance, MarR family	2 Oceanobacillus iheyensis HTE831* Gene: OB0603: Transcriptional regulator of thiol stress resistance, MarR family Site: position = -49 score = 4.09282 sequence = TAAACTTAATTAAAGATA Gene: OB0445: Transcriptional regulator of thiol stress resistance, MarR family	* Paenibacillus sp. JDR-2 Site: position = -38 score = 5.67155 sequence = TATCTTAAAATCAAGATA Gene: Pjdr2_5975: Transcriptional regulator of thiol stress resistance, MarR family	Transcriptional regulator of thiol stress resistance, MarR family
mhqO	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU05490: Lactoylglutathione lyase	Bacillus amyloliquefaciens FZB42 Gene: RBAM_002880: Lactoylglutathione lyase	* Bacillus pumilus SAFR-032 Site: position = -81 score = 5.71992 sequence = TATCCTTAATTCGAGATA Site: position = -43 score = 6.7661 sequence = TATCTCGAATTCGAGATA Gene: BPUM_3715: Lactoylglutathione lyase	Bacillus licheniformis DSM 13 Gene: BLi02024: Lactoylglutathione lyase	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	* Bacillus cereus ATCC 14579 Site: position = -118 score = 6.7661 sequence = TATCTCGAATTCGAGATA Site: position = -177 score = 6.42387 sequence = TATCTTGAAATCGAGATA Gene: BC3643: Lactoylglutathione lyase	Bacillus halodurans C-125	* Bacillus clausii KSM-K16 Site: position = -57 score = 5.15311 sequence = TATTTCGAATTTAATATA Gene: ABC4022: Lactoylglutathione lyase	* Oceanobacillus iheyensis HTE831 Site: position = -50 score = 4.53726 sequence = TATAATTAATTAAAGATA Gene: OB2142: Lactoylglutathione lyase	* Paenibacillus sp. JDR-2 Site: position = -49 score = 5.11844 sequence = TATCTTAAATTAAAGATT Gene: Pjdr2_5974: Lactoylglutathione lyase	Lactoylglutathione lyase
mhqD	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU19560: Carboxylesterase (EC 3.1.1.1)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_019320: Carboxylesterase (EC 3.1.1.1)	Bacillus pumilus SAFR-032 Gene: BPUM_3714: Carboxylesterase (EC 3.1.1.1)	* Bacillus licheniformis DSM 13 Site: position = -213 score = 6.42387 sequence = TATCTTGAATTCAAGATA Gene: BLi02276: Carboxylesterase (EC 3.1.1.1)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC3642: Carboxylesterase (EC 3.1.1.1)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC2025: Carboxylesterase (EC 3.1.1.1)	* Oceanobacillus iheyensis HTE831 Site: position = -183 score = 3.81472 sequence = GCTGTTTATATCGAGATT Site: position = -31 score = 3.86529 sequence = TATCGAGAATTAAAGGGA Gene: OB0444: Carboxylesterase (EC 3.1.1.1)	Paenibacillus sp. JDR-2 Gene: Pjdr2_5973: Carboxylesterase (EC 3.1.1.1)	Carboxylesterase (EC 3.1.1.1)
ywrF	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU36080: Flavin reductase domain protein FMN-binding	Bacillus amyloliquefaciens FZB42 Gene: RBAM_033240: Flavin reductase domain protein FMN-binding	2 Bacillus pumilus SAFR-032 Gene: BPUM_3713: Flavin reductase domain protein FMN-binding Gene: BPUM_3269: Flavin reductase domain protein FMN-binding	Bacillus licheniformis DSM 13 Gene: BLi02025: Flavin reductase domain protein FMN-binding	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	* Bacillus cereus ATCC 14579 Site: position = -154 score = 5.317 sequence = TATCTCAAATTTGAGATT Gene: BC5322: Flavin reductase domain protein FMN-binding	Bacillus halodurans C-125 Gene: BH2278: Flavin reductase domain protein FMN-binding	* Bacillus clausii KSM-K16 Site: position = -58 score = 5.58344 sequence = TATATTAAATTCGAGATA Gene: ABC0534: Flavin reductase domain protein FMN-binding	Oceanobacillus iheyensis HTE831 Gene: OB3102: Flavin reductase domain protein FMN-binding	Paenibacillus sp. JDR-2 Gene: Pjdr2_5972: Flavin reductase domain protein FMN-binding	Flavin reductase domain protein FMN-binding
mhqN	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -163 score = 5.42567 sequence = TATCTCATATTCAAGATA Site: position = -35 score = 6.7661 sequence = TATCTCGAATTCGAGATA Gene: BSU05480: Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)	* Bacillus amyloliquefaciens FZB42 Site: position = -35 score = 6.7661 sequence = TATCTCGAATTCGAGATA Site: position = -178 score = 6.3083 sequence = TATCTCGAATTCAAGATT Gene: RBAM_002870: Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)	Bacillus pumilus SAFR-032 Gene: BPUM_0487: Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)	* Bacillus licheniformis DSM 13 Site: position = -57 score = 6.33576 sequence = TATCTCGAATTCGAAATA Gene: BLi02023: Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC4340: Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_6191: Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)	Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)
mhqP	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU05500: Putative membrane bound oxidoreductase	Bacillus amyloliquefaciens FZB42 Gene: RBAM_002890: Putative membrane bound oxidoreductase	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_1579: Putative membrane bound oxidoreductase	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_4806: Putative membrane bound oxidoreductase	Putative membrane bound oxidoreductase
Aflv_1580	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_1580: Pirin-like protein	* Geobacillus kaustophilus HTA426 Site: position = -322 score = 6.19272 sequence = AATCTCGAATTCGAGATT Gene: GK3094: Pirin-like protein	* Bacillus cereus ATCC 14579 Site: position = -34 score = 6.47941 sequence = AATCTCGAATTCGAGATA Gene: BC5037: Pirin-like protein	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_5923: Pirin-like protein	Pirin-like protein
mhqE	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -33 score = 6.42387 sequence = TATCTTGAAATCGAGATA Gene: BSU19570: Glyoxalase/bleomycin resistance protein/dioxygenase	* Bacillus amyloliquefaciens FZB42 Site: position = -34 score = 6.42387 sequence = TATCTCGAAATCAAGATA Gene: RBAM_019330: Glyoxalase/bleomycin resistance protein/dioxygenase	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Glyoxalase/bleomycin resistance protein/dioxygenase

CRON 2.
azoR2	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -139 score = 5.45583 sequence = AATCTTTAATTCGAGATG Gene: BSU33540: FMN-dependent NADH-azoreductase	* Bacillus amyloliquefaciens FZB42 Site: position = -137 score = 5.556 sequence = TATACTGATTTCGAGATA Gene: RBAM_030720: FMN-dependent NADH-azoreductase	* Bacillus pumilus SAFR-032 Site: position = -190 score = 5.69965 sequence = TATCTTGATTTCGAGACT Gene: BPUM_0385: FMN-dependent NADH-azoreductase	Bacillus licheniformis DSM 13 Gene: BLi03573: FMN-dependent NADH-azoreductase	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK3428: FMN-dependent NADH-azoreductase	* Bacillus cereus ATCC 14579 Site: position = -42 score = 5.69965 sequence = AATCTTGAATTAAAGATA Gene: BC2194: FMN-dependent NADH-azoreductase	Bacillus halodurans C-125 Gene: BH4043: FMN-dependent NADH-azoreductase	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	FMN-dependent NADH-azoreductase

CRON 3.
mhqA	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -40 score = 6.59499 sequence = TATCTCGAAATCGAGATA Gene: BSU12870: Lactoylglutathione lyase	* Bacillus amyloliquefaciens FZB42 Site: position = -38 score = 6.59499 sequence = TATCTCGAAATCGAGATA Gene: RBAM_012720: Lactoylglutathione lyase	* Bacillus pumilus SAFR-032 Site: position = -40 score = 6.59499 sequence = TATCTTGAATTCGAGATA Gene: BPUM_1180: Lactoylglutathione lyase	* Bacillus licheniformis DSM 13 Site: position = -38 score = 6.47941 sequence = AATCTCGAATTCGAGATA Gene: BLi01388: Lactoylglutathione lyase	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Lactoylglutathione lyase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MhqR - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --