Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of CymR regulog to Geobacillus sp. WCH70

Reference regulog properties
Source regulog: CymR - Bacillales
Regulator type: Transcription factor
Regulator family: Rrf2
Regulation mode: repressor
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine; CysK, cysteine synthetase
Phylum: Firmicutes
Propagated regulon:
Target genome Geobacillus sp. WCH70
Orthologous TF(s) GWCH70_2499
Regulated genes 6
Built upon 65 sites [see more]
Predicted regulatory interactions in Geobacillus sp. WCH70
Locus tag Position Score Sequence
Position: -38
Score: 5.2
Sequence: CAAATTCGATAAAATTAATCGGGATTA
Locus tag: GWCH70_0067
GWCH70_0067 -38 5.2 CAAATTCGATAAAATTAATCGGGATTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Bacillus subtilis subsp. subtilis str. 168 BSU00730 -39 5.4 TAATACCAATACAAATAGTCGGAAATT
Bacillus amyloliquefaciens FZB42 RBAM_000840 -39 5.8 TAATACCAATAAATTTAGTCGGAAATT
Bacillus pumilus SAFR-032 BPUM_0057 -40 4.6 TtAaTaCaATaAAATTAcTcGGAgaTA
Bacillus licheniformis DSM 13 BLi00089 -38 5.6 TAATCCCAATAAAATTACTCGGAAATT
Anoxybacillus flavithermus WK1 Aflv_0065 -30 5 CAAATTCTATAAAAATACTCGGGATTA
Geobacillus kaustophilus HTA426 GK0065 -38 4.7 CAAAGTCGATAAAATTAATGGGGATTA
Bacillus cereus ATCC 14579 BC0075 -39 5.3 TAAAACCAATAAAAATACTCGGTGTTA
Bacillus halodurans C-125 BH0088 -39 5.2 GAAAACCAATAAATTTACTTGGGATTA
Bacillus clausii KSM-K16 ABC0109 -42 4.9 TAAAACCAATGAAGATACTAGGGATTG
Oceanobacillus iheyensis HTE831 OB0084 -41 6 TAAATCTTATAAAAATACTTGGAATTA
Paenibacillus sp. JDR-2 Pjdr2_0074 -44 5.7 AAAAACCAACTAAATTAGTCGGAATAA
Position: -50
Score: 5.3
Sequence: TAAATCATAGTTTTCCTATATGAAATA
Locus tag: GWCH70_0412
GWCH70_0412 -50 5.3 TAAATCATAGTTTTCCTATATGAAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: sat
Ortholog function: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
Bacillus amyloliquefaciens FZB42 RBAM_015420 -299 4.7 TTATTCCTATCAAAAAACTCGGGTTGA
Anoxybacillus flavithermus WK1 Aflv_0314 -48 5.6 TTAATCCTAGTTGTTTTATAAGAATAA
Bacillus halodurans C-125 BH1487 -73 5.3 TAAATCATATCAAATTACATGGAATTA
Bacillus clausii KSM-K16 ABC0612 -265 4.9 AAATACCGAGTTTGTTAATCAGGATAA
Oceanobacillus iheyensis HTE831 OB1659 -98 5.4 CAATTCACATTGTATTACTATGAATTA
Position: -305
Score: 5.1
Sequence: TAATTCCTATCGAAAAACTAGGATTGA
Locus tag: GWCH70_0413
GWCH70_0413 -305 5.1 TAATTCCTATCGAAAAACTAGGATTGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysH
Ortholog function: Phosphoadenylyl-sulfate reductase (EC 1.8.4.8)
Bacillus amyloliquefaciens FZB42 RBAM_015400 -299 4.7 TTATTCCTATCAAAAAACTCGGGTTGA
Anoxybacillus flavithermus WK1 Aflv_0316 -100 5.1 AAATTCCGATAGAAAAACTAGGATTGA
Bacillus halodurans C-125 BH1486 -73 5.3 TAAATCATATCAAATTACATGGAATTA
Bacillus clausii KSM-K16 ABC0611 -265 4.9 AAATACCGAGTTTGTTAATCAGGATAA
Oceanobacillus iheyensis HTE831 OB1652 -98 5.4 CAATTCACATTGTATTACTATGAATTA
Paenibacillus sp. JDR-2 Pjdr2_5647 -45 5.2 AATAGCATATGAATTTACTTGGAATTA
Position: -50
Score: 6.1
Sequence: AAAATCATAGTATATTTATAGGAATTA
Locus tag: GWCH70_2477
GWCH70_2477 -50 6.1 AAAATCATAGTATATTTATAGGAATTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yrrT
Ortholog function: SAM-dependent methyltransferase
Bacillus subtilis subsp. subtilis str. 168 BSU27280 -49 6.1 TAATCCATAGTATACTTATAGGAATTA
Bacillus amyloliquefaciens FZB42 RBAM_024380 -49 5.9 TAATCCATACTATACTCATAGGAATTA
Bacillus pumilus SAFR-032 BPUM_2363 -51 5.4 TAAAACATACTATACGCATAGGAATAA
Bacillus licheniformis DSM 13 BLi02856 -54 5.8 TAAATCATACTATACTTATAGGAATTG
Anoxybacillus flavithermus WK1 Aflv_0758 -36 6.4 TAATTCATACTATACTTATAGGAATTA
Geobacillus kaustophilus HTA426 GK2543 -51 5.9 AAAAACATACTATATTTATAGGAATTA
Bacillus cereus ATCC 14579 BC4369 -29 5.1 TAAAACCGATAAGAAAAAGGGGAATTT
Paenibacillus sp. JDR-2 Pjdr2_5106 -105 5.2 TAAATCCGATTAATAAGGTTGGAAAAA
Position: -217
Score: 5.5
Sequence: TAAATCCTATAGGTAAACTACGAATTA
Position: -157
Score: 5
Sequence: TTAATCATAGTTAACCTATAGGAATAG
Locus tag: GWCH70_2623
GWCH70_2623 -217 5.5 TAAATCCTATAGGTAAACTACGAATTA
-157 5 TTAATCATAGTTAACCTATAGGAATAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: ssuB
Ortholog function: Aliphatic sulfonate ABC transporter (ATP-binding protein)
Bacillus subtilis subsp. subtilis str. 168 BSU08830 -167 4.6 TAAAAAAGAGTTGACATATCGGAATAA
Bacillus cereus ATCC 14579 BC2912 -174 5.7 TAAAACCTAGTTGACTTATCGGAAATA
Paenibacillus sp. JDR-2 Pjdr2_0756 -70 5.3 TAATTCCAACTATTCCAATAAGGAAAA
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