Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of BirA regulog to Anoxybacillus flavithermus WK1

Reference regulog properties
Source regulog: BirA - Bacillales
Regulator type: Transcription factor
Regulator family: BirA
Regulation mode: repressor
Biological process: Biotin biosynthesis
Effector: Biotin
Phylum: Firmicutes
Propagated regulon:
Target genome Anoxybacillus flavithermus WK1
Orthologous TF(s) Aflv_1125
Regulated genes 4
Built upon 36 sites [see more]
Predicted regulatory interactions in Anoxybacillus flavithermus WK1
Locus tag Position Score Sequence
Position: -52
Score: 8.7
Sequence: TTGTTAAC-(15)-GTTGACAA
Locus tag: Aflv_1070
Aflv_1070 -52 8.7 TTGTTAAC-(15)-GTTGACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioD
Ortholog function: Dethiobiotin synthetase (EC 6.3.3.3)
Anoxybacillus flavithermus WK1 Aflv_1070 -52 8.7 TTGTTAAC-(15)-GTTGACAA
Position: -45
Score: 8.5
Sequence: ATGTAAAC-(15)-GTTTACAA
Locus tag: Aflv_1163
Aflv_1163 -45 8.5 ATGTAAAC-(15)-GTTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioF
Ortholog function: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
Anoxybacillus flavithermus WK1 Aflv_1163 -45 8.5 ATGTAAAC-(15)-GTTTACAA
Geobacillus kaustophilus HTA426 GK2128 -46 8.4 ATGTAAAC-(15)-GTTTACAT
Bacillus cereus ATCC 14579 BC4117 -45 8.7 ATGTTAAC-(15)-GTTAACAT
Bacillus halodurans C-125 BH3907 -66 8.8 ATGTTAAC-(15)-GTTAACAA
Paenibacillus sp. JDR-2 Pjdr2_1464 40 8.8 TTGTTAAC-(18)-GTTAACAA
Position: -55
Score: 8.7
Sequence: TTGTTAAC-(15)-GTTGACAT
Locus tag: Aflv_1376
Aflv_1376 -55 8.7 TTGTTAAC-(15)-GTTGACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioB
Ortholog function: Biotin synthase (EC 2.8.1.6)
Bacillus subtilis subsp. subtilis str. 168 BSU30200 -85 8.8 TTGTTAAC-(15)-GTTAACAA
Bacillus amyloliquefaciens FZB42 RBAM_018250 -126 7.2 CAGTTAAC-(15)-GTTGACAT
-64 8.2 GTGTTAAC-(15)-GTTAACAT
Bacillus pumilus SAFR-032 BPUM_2779 -48 8.7 ATGTTAAC-(15)-GTTAACAT
Bacillus licheniformis DSM 13 BLi00770 -55 8.7 ATGTTAAC-(15)-GTTAACAT
Anoxybacillus flavithermus WK1 Aflv_1376 -55 8.7 TTGTTAAC-(15)-GTTGACAT
Geobacillus kaustophilus HTA426 GK1570 -86 7.8 AAGTAAAC-(15)-GTTGACAA
Bacillus cereus ATCC 14579 BC4114 -45 8.7 ATGTTAAC-(15)-GTTAACAT
Bacillus halodurans C-125 BH1748 -56 8.7 TTGTTAAC-(15)-GTTTACAA
Paenibacillus sp. JDR-2 Pjdr2_1463 40 8.8 TTGTTAAC-(18)-GTTAACAA
Position: -31
Score: 8.1
Sequence: TCGTTAAC-(15)-GTTAACAA
Locus tag: Aflv_2398
Aflv_2398 -31 8.1 TCGTTAAC-(15)-GTTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioY1
Ortholog function: Substrate-specific component BioY of biotin ECF transporter
Bacillus subtilis subsp. subtilis str. 168 BSU32030 -87 8.7 TTGTTAAC-(15)-GTTGACAA
Bacillus amyloliquefaciens FZB42 RBAM_029080 -84 7.9 TAGTAAAC-(15)-GTTGACAA
Bacillus pumilus SAFR-032 BPUM_2863 -83 8.7 TTGTTAAC-(15)-GTTGACAA
Bacillus licheniformis DSM 13 BLi03385 -89 8.7 TTGTTAAC-(15)-GTTGACAA
Anoxybacillus flavithermus WK1 Aflv_2398 -31 8.1 TCGTTAAC-(15)-GTTAACAA
Geobacillus kaustophilus HTA426 GK2944 -31 8.6 TTGTTAAC-(15)-GTTTACAT
Bacillus cereus ATCC 14579 BC4917 107 8.7 ATGTTAAC-(16)-GTTAACAT
Bacillus halodurans C-125 BH3358 -87 8.6 ATGTCAAC-(15)-GTTGACAA
-33 7.8 ATGTTAAC-(15)-GTAAACAT
Oceanobacillus iheyensis HTE831 OB2346 -81 8.6 TTGTCAAC-(15)-GTTGACAA
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