Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of TyrR regulog to Klebsiella pneumoniae 342

Reference regulog properties
Source regulog: TyrR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: TyrR
Regulation mode: activator (repressor)
Biological process: Aromatic amino acid metabolism
Effector: Tyrosine; Phenylalanine
Phylum: Proteobacteria/gamma
Propagated regulon:
Target genome Klebsiella pneumoniae 342
Orthologous TF(s) KPK_5506, KPK_3109
Regulated genes 7
Built upon 106 sites [see more]
Predicted regulatory interactions in Klebsiella pneumoniae 342
Locus tag Position Score Sequence
Position: -127
Score: 4.9
Sequence: GCGTAAAGTAAATAATACAG
Locus tag: KPK_0554
KPK_0554 -127 4.9 GCGTAAAGTAAATAATACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: mtr
Ortholog function: Tryptophan-specific transport protein
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03569 -128 4.9 GCGTAAACTAAATAATACAG
Position: -103
Score: 4.5
Sequence: GCGTAACTATTGCTTTACAC
Locus tag: KPK_1400
KPK_1400 -103 4.5 GCGTAACTATTGCTTTACAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: ipdC
Ortholog function: Indole-3-pyruvate decarboxylase (EC 4.1.1.74)
Salmonella typhimurium LT2 STM2405 -100 4.5 CTGTAAACATTGTTTTCCAG
Citrobacter koseri ATCC BAA-895 CKO_00409 -101 3.8 CTGTAAATCCTGCTTTCCAC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02740 -97 5 GCGTAATTATTGCTTTACAC
Position: -110
Score: 5.4
Sequence: GCGTAAAGATAAAATTACAG
Locus tag: KPK_1878
KPK_1878 -110 5.4 GCGTAAAGATAAAATTACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: tyrP
Ortholog function: Tyrosine-specific transport protein
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02404 -110 5.3 ATGTAAACATTTCATTACAC
Position: -90
Score: 4.2
Sequence: CTGTCAATAATTGTTGACAG
Locus tag: KPK_3109
KPK_3109 -90 4.2 CTGTCAATAATTGTTGACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: tyrR
Ortholog function: Transcriptional regulator of aromatic amino acid biosynthesis
Escherichia coli str. K-12 substr. MG1655 b1323 -89 3.7 GTGTCAATGATTGTTGACAG
Salmonella typhimurium LT2 STM1683 -89 4.2 CTGTCAATATTTGTTGACAG
Citrobacter koseri ATCC BAA-895 CKO_01393 -90 4.2 CTGTCAATAATTGTTGACAG
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_01305 -90 4.2 CTGTCAATAATTGTTGACAG
Enterobacter sp. 638 Ent638_2152 -86 3.7 CTGTCAATATCTGTTGACAG
Erwinia amylovora ATCC 49946 EAM_1834 -96 3.9 CTGTCAACTTTTCATGACAG
Serratia proteamaculans 568 Spro_2617 -98 3.6 CTGTCAACTTTTGCTGACAG
Proteus mirabilis HI4320 PMI1369 -96 3.7 GTGTCAACTTTTGCTGACAA
Photorhabdus luminescens subsp. laumondii TTO1 plu2580 -178 3.7 TTTTATAATCAATCTTACAA
Position: -79
Score: 4.7
Sequence: CTGTAAGTTTTTATTGACAG
Locus tag: KPK_3603
KPK_3603 -79 4.7 CTGTAAGTTTTTATTGACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: ompF
Ortholog function: outer membrane porin F
Salmonella typhimurium LT2 STM0999 -77 4.7 CTGTAAAGTTTTATTGACGG
Enterobacter sp. 638 Ent638_1448 -77 4.5 CCGGAAATATTTATTGACAG
Position: -164
Score: 4.6
Sequence: ATGCAATGATAAGTTTACAT
Position: -100
Score: 4.7
Sequence: GTGTAACGTTTTGTTTACGA
Locus tag: KPK_4354
KPK_4354 -164 4.6 ATGCAATGATAAGTTTACAT
-100 4.7 GTGTAACGTTTTGTTTACGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: aroL
Ortholog function: Shikimate kinase III (EC 2.7.1.71)
Escherichia coli str. K-12 substr. MG1655 b0388 -182 5.6 ATGTAATTTATTATTTACAC
-106 5 GTGGAATTTTTTCTTTACAA
Salmonella typhimurium LT2 STM0388 -181 5.4 ATGTAATGAAAAATTTACAG
-107 5.8 GTGTAAATTATTATTTACAT
Citrobacter koseri ATCC BAA-895 CKO_02783 -238 5.4 ATGTAATGTTATTTTTACAC
-163 5 GTGGAATGATTTATTTACAT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_00332 -165 4.6 ATGCAATGATAAGTTTACAT
-101 5.3 GTGTAATTTTTTCTTTACGT
Enterobacter sp. 638 Ent638_0859 -182 4.5 ATGCAATGATTTCTTTACAG
-108 4.9 CTGTAATCCAATTTTTACAA
Erwinia amylovora ATCC 49946 EAM_0932 -126 4.5 CTGTAAATAAAACGTTACTG
Yersinia pestis KIM y0972 -174 5 GTGTATTATTAATTTTACGT
Serratia proteamaculans 568 Spro_1018 -122 4.9 TCGTAAATATTGAAATACAG
Proteus mirabilis HI4320 PMI0371 -57 5.5 TTGTAAATTTTAGATTACAC
Position: -82
Score: 3.9
Sequence: GTGTGCCGTTTTATTTACGA
Position: -60
Score: 3.9
Sequence: TAGTGCTGTTTACTTTACAC
Locus tag: KPK_4746
KPK_4746 -82 3.9 GTGTGCCGTTTTATTTACGA
-60 3.9 TAGTGCTGTTTACTTTACAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: COG2814
Ortholog function: Predicted tyrosine transporter, COG2814 family
Citrobacter koseri ATCC BAA-895 CKO_03376 -87 4.4 GAGTATTGAATTGTTTACGA
-65 4.9 TAGTAATTTTTGATTTACAC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_00010 -82 3.9 GTGTGCCGTTTTATTTACGA
-60 4.4 TAGTGATTTTTACTTTACAC
Enterobacter sp. 638 Ent638_0572 -60 4.9 TAGTAATTTTTTCTTTACGA
-37 4.4 CTGTAAAATTAAATCAACAA
Yersinia pestis KIM y3709 -68 4.2 TAGTCATGTTAACTTTACAA
Serratia proteamaculans 568 Spro_0690 -87 3.7 GTGTGAAAATAATTTGCCGT
-65 4 TAGTAAGGATTCGTTTACAG
Erwinia carotovora subsp. atroseptica SCRI1043 ECA3884 -90 4 GTGTATAAAAATTTTGCCGA
-68 5 TAGTAATTTATACTTTACAC
Edwardsiella tarda EIB202 ETAE_0574 -66 3.7 TTATATTTCTATTTTTGCAA