Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of NanR regulog to Streptococcus pneumoniae Hungary19A-6

Reference regulog properties
Source regulog: NanR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: RpiR
Regulation mode: repressor
Biological process: Sialic acid utilization
Effector: N-acetylneuraminic acid
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae Hungary19A-6
Orthologous TF(s) SPH_1782, SPH_1473
Regulated genes 3
Built upon 16 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae Hungary19A-6
Locus tag Position Score Sequence
Position: -99
Score: 5.7
Sequence: TTGGAAACTAGTTTCTAA
Locus tag: SPH_1473
SPH_1473 -99 5.7 TTGGAAACTAGTTTCTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nanR
Ortholog function: Sialic acid utilization transcriptional regulator NanR, RpiR family
Streptococcus mitis B6 smi_0792 -96 5.7 TTGGAAACTAGTTTCTAA
Streptococcus pneumoniae TIGR4 SP_1331 -94 5.7 TTGGAAACTAGTTTCTAA
Position: -158
Score: 6.4
Sequence: TCTGAAACTACTTTCAAA
Locus tag: SPH_1784
SPH_1784 -158 6.4 TCTGAAACTACTTTCAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nanA
Ortholog function: N-acetylneuraminate lyase (EC 4.1.3.3)
Streptococcus mitis B6 smi_0608 -160 6.2 TCTGAAACTACTTTCAAG
Streptococcus pneumoniae TIGR4 SP_1676 -158 6.4 TCTGAAACTACTTTCAAA
Position: -143
Score: 5.9
Sequence: TCTGAAAGTACTTTTAGA
Locus tag: SPH_1791
SPH_1791 -143 5.9 TCTGAAAGTACTTTTAGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nanE
Ortholog function: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Streptococcus agalactiae 2603V/R SAG0033 -146 5.9 TCTGAAACTACTTTCACG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0241 -104 5.6 AATGAAAGTACTTCCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0245 -104 5.9 AATGAAAGTAGTTTCTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0118 -147 6.3 TCTGAAACTACTTTCAGA
Streptococcus mitis B6 smi_0602 -135 6.3 TCTGAAACTACTTTCAGA
Streptococcus pneumoniae TIGR4 SP_1685 -136 5.9 TCTGAAAGTACTTTTAGA
Streptococcus sanguinis SK36 SSA_0071 -252 5.8 CCTGAAAGTACTTTCAGG
Streptococcus suis 05ZYH33 SSU05_1402 -147 5.8 TCTGAAACTATTTTCAGG
Streptococcus uberis 0140J SUB1658 -147 6 TCTGAAAATAGTTTCAGA
-108 5.1 TTTGAAAGTATTATCTAA
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