Propagation of Rex regulog to Streptococcus mutans NN2025

Reference regulog properties
Source regulog:	Rex - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus mutans NN2025
Orthologous TF(s)	SmuNN2025_0982
Regulated genes	13

Built upon 161 sites [see more]

Predicted regulatory interactions in *Streptococcus mutans NN2025*
	Locus tag	Position	Score	Sequence
Position: -163 Score: 4.1 Sequence: TTTTGAAAAACTTCCAAA Locus tag: SmuNN2025_0075
	SmuNN2025_0075	-163	4.1	TTTTGAAAAACTTCCAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nirC
Ortholog function: Formate/nitrite family of transporters
Streptococcus agalactiae 2603V/R	SAG1084	-32	4.5	AAGTTAATAAAATCACAT
Streptococcus gordonii str. Challis substr. CH1	SGO_1137	-40	3.8	ATGATATATTGGTCATAA
Streptococcus mitis B6	smi_1009	-41	4.3	TTGTGATATAATTATCAG
Streptococcus pneumoniae TIGR4	SP_1215	-41	5	TTGTGATATAATTATCAA
Streptococcus sanguinis SK36	SSA_1098	-44	4.5	TTGTGATATACTATACAT

Position: -61 Score: 4.6 Sequence: AAGTGATAAAATAAACAA Locus tag: SmuNN2025_0092
	SmuNN2025_0092	-61	4.6	AAGTGATAAAATAAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fba
Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Streptococcus gallolyticus UCN34	GALLO_0255	-60	4.2	TTGTGATAAAATGTACGT
Streptococcus gordonii str. Challis substr. CH1	SGO_1745	-61	4.6	AAGTGATAAAATAAACAA
Streptococcus mutans UA159	SMU.99	-61	4.6	AAGTGATAAAATAAACAA
Streptococcus pneumoniae TIGR4	SP_0605	-62	4.5	AAGTGATAAAATGAACAA
Streptococcus sanguinis SK36	SSA_1992	-62	4.6	AAGTGATAAAATAAACAA

Position: -130 Score: 5.3 Sequence: TTGGGAAAAAATTCACAA Position: -96 Score: 4.8 Sequence: TTGTGAAAAGGGTTACAA Position: -74 Score: 4.8 Sequence: AAGTGAAGAAAATCACAA Locus tag: SmuNN2025_0126
	SmuNN2025_0126	-130	5.3	TTGGGAAAAAATTCACAA
		-96	4.8	TTGTGAAAAGGGTTACAA
		-74	4.8	AAGTGAAGAAAATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
Lactococcus lactis subsp. cremoris SK11	LACR_2457	-101	5	TTGTAAATTTCATCACAA
		-58	4.7	TTGTTAAACTATTCACGT
		-34	4.5	AAGTGAATGAAATCACAA
Lactococcus lactis subsp. lactis Il1403	L13145	-101	5	TTGTAAAAACTATCACAA
		-58	4.7	TTGTTAAACTATTCACGT
		-34	4.3	AAGTGAATGAAGTCACAA
Streptococcus gallolyticus UCN34	GALLO_0220	-260	4.2	TTGTAATAAAAATGAAAA
		-216	4.3	TTGAAAAAAGTTTAATAT
		-195	4.7	TGGTGAAGAATATCACAA
Streptococcus mutans UA159	SMU.148	-130	5.3	TTGGGAAAAAATTCACAA
		-96	4.8	TTGTGAAAAGGGTTACAA
		-74	4.8	AAGTGAAGAAAATCACAA

Position: -64 Score: 4.1 Sequence: ATGTGATGTTTTTCACTT Locus tag: SmuNN2025_0691
	SmuNN2025_0691	-64	4.1	ATGTGATGTTTTTCACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: frdC
Ortholog function: Fumarate reductase
Streptococcus mutans UA159	SMU.1410	-57	4.1	ATGTGATGTTTTTCACTT

Position: -49 Score: 4.6 Sequence: TTGTGGTATGATTAACAT Locus tag: SmuNN2025_0809
	SmuNN2025_0809	-49	4.6	TTGTGGTATGATTAACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: eno
Ortholog function: Enolase (EC 4.2.1.11)
Lactococcus lactis subsp. cremoris SK11	LACR_0668	-80	4.4	TTGAAAAATCTTTCAAAA
Lactococcus lactis subsp. lactis Il1403	L0007	-80	4.4	TTGAAAAATCTTTCAAAA
Streptococcus agalactiae 2603V/R	SAG0628	-123	4.4	TAGTGATTTTTTTATCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0704	-52	4.8	TTGTGGTATTATTAACAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0774	-52	4.8	TTGTGGTATTATTAACAT
Streptococcus gallolyticus UCN34	GALLO_1458	-38	4.4	GTGTAAAAATATTAAAAA
Streptococcus mutans UA159	SMU.1247	-49	4.6	TTGTGGTATGATTAACAT
Streptococcus pyogenes M1 GAS	SPy0731	-52	4.3	TTGTGGTATTATGAACAT
Streptococcus sanguinis SK36	SSA_0886	-111	4.7	TTGTGCAAAATTTCTCAA
		-35	4.2	TAGTAAATAATTTTAAAT
Streptococcus uberis 0140J	SUB0655	-101	4.3	AAGTGAAATTTTTCATTA
		-52	4.2	TTGTGATATTATGGACAT

Position: -154 Score: 3.8 Sequence: TTTTATATTATATCACAA Position: -81 Score: 4.4 Sequence: TAGTGACTTTCTTAACAA Locus tag: SmuNN2025_0926
	SmuNN2025_0926	-154	3.8	TTTTATATTATATCACAA
		-81	4.4	TAGTGACTTTCTTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ldh
Ortholog function: L-lactate dehydrogenase (EC 1.1.1.27)
Lactococcus lactis subsp. cremoris SK11	LACR_1455	-63	4.1	TTGTTGAAAAGATTATAT
Lactococcus lactis subsp. lactis Il1403	L0017	-63	4.1	TTGTTGAAAAGATTATAT
Streptococcus agalactiae 2603V/R	SAG0959	-102	4.4	TTGCAAATTTTTTCACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0911	-77	4.2	ATGACAAACAATTCTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1022	-79	3.9	ATGACAAAGACATTACAA
Streptococcus gallolyticus UCN34	GALLO_1129	-106	4	TTTTCAAAGTTTTTACAA
Streptococcus gallolyticus UCN34	GALLO_2034	-85	3.8	TTATTATACAATTCCAAA
Streptococcus gordonii str. Challis substr. CH1	SGO_1232	-118	3.8	TTCTAAAAACGTTTACAT
Streptococcus mitis B6	smi_1006	-62	4.2	AAGTGATAAAATTAAAAT
Streptococcus mutans UA159	SMU.1115	-81	4.4	TAGTGACTTTCTTAACAA
Streptococcus pyogenes M1 GAS	SPy1151	-77	4.1	ATGACAAACAATTATCAA
Streptococcus sanguinis SK36	SSA_1221	-116	4.5	TTGTAAAAACGTTTACAT
Streptococcus uberis 0140J	SUB0879	-77	4.3	GTGACAAACTATTCACAA

Position: -117 Score: 4.4 Sequence: TTGTTATAAAAAAAACTA Position: -58 Score: 4.5 Sequence: ATGTTGCATTTTTCACAA Locus tag: SmuNN2025_0982
	SmuNN2025_0982	-117	4.4	TTGTTATAAAAAAAACTA
		-58	4.5	ATGTTGCATTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rex
Ortholog function: Redox-sensitive transcriptional regulator Rex, Rex family
Lactococcus lactis subsp. cremoris SK11	LACR_1156	-74	5.3	TTGATAAAATTATCACAA
Lactococcus lactis subsp. lactis Il1403	L71932	-75	5.3	TTGATAAAATTATCACAA
Streptococcus agalactiae 2603V/R	SAG1100	-36	4.5	TAATAAAATTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1050	-31	4.4	TAGTTGCATATTTCACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_1228	-54	4.7	TAGTTGATTTTTTCACAA
Streptococcus mitis B6	smi_1188	-57	5	TTGTTGATTTTTTCACAA
Streptococcus mutans UA159	SMU.1053	-117	4.4	TTGTTATAAAAAAAACTA
		-58	4.5	ATGTTGCATTTTTCACAA
Streptococcus pneumoniae TIGR4	SP_1090	-57	5	TTGTTGATTTTTTCACAA
Streptococcus pyogenes M1 GAS	SPy1120	-76	4.5	ATGTTGCATTTTTCACAA
Streptococcus sanguinis SK36	SSA_1216	-55	4.7	TAGTTGATTTTTTCACAA
Streptococcus suis 05ZYH33	SSU05_1069	-100	4.5	CTGTTGATTTTTTCACAA
Streptococcus thermophilus CNRZ1066	str1463	-39	4.6	TTGTTGCAATCTTCACAA
Streptococcus uberis 0140J	SUB0845	-52	4.4	TTGTTACAATAGTAACAT

Position: -30 Score: 4.2 Sequence: TTGTAAATAAAAGAAGAA Locus tag: SmuNN2025_1282
	SmuNN2025_1282	-30	4.2	TTGTAAATAAAAGAAGAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: tpi
Ortholog function: Triosephosphate isomerase (EC 5.3.1.1)
Streptococcus agalactiae 2603V/R	SAG0763	-72	4	TCGTGAAACTTTTAATTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0629	-97	5.1	TTGTGAAAATATTCCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1321	-97	5	TTGTGAAAATATTACTAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0762	-89	4.5	TTGATAAAAACTTAGCAA
Streptococcus pyogenes M1 GAS	SPy0613	-97	5.1	TTGTGAAAATATTCCTAA
Streptococcus thermophilus CNRZ1066	str0488	-46	4.7	TTGTGATAAAATAAACGA
Streptococcus uberis 0140J	SUB0605	-98	5.2	TTGTGAAAATTATCCCAA

Position: -267 Score: 4.3 Sequence: GTGTTATAATAGTAACAA Position: -258 Score: 3.8 Sequence: TAGTAACAATAAACATAA Locus tag: SmuNN2025_1504
	SmuNN2025_1504	-267	4.3	GTGTTATAATAGTAACAA
		-258	3.8	TAGTAACAATAAACATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pncB
Ortholog function: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)
Lactococcus lactis subsp. cremoris SK11	LACR_1202	-218	4	TTGTAGTATAAAAAACAT
Lactococcus lactis subsp. lactis Il1403	L107468	-181	3.9	TTGTAGTACAAAAAACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1714	-39	4.7	ATGTTATAATAGTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1574	-39	4.3	ATGGTATAATAATAACAA
Streptococcus mitis B6	smi_1492	-114	4.3	TTGTTACTCTTTTCTCAA
Streptococcus mutans UA159	SMU.464	-265	4.3	GTGTTATAATAGTAACAA
Streptococcus pneumoniae TIGR4	SP_1421	-114	4.3	TTGTTACTCTTTTCTCAA
Streptococcus pyogenes M1 GAS	SPy1653	-39	4.7	ATGTTATAATAGTAACAA

Position: -46 Score: 4.7 Sequence: TTGTGATATAATTATCAT Locus tag: SmuNN2025_1589
	SmuNN2025_1589	-46	4.7	TTGTGATATAATTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgk
Ortholog function: Phosphoglycerate kinase (EC 2.7.2.3)
Lactococcus lactis subsp. cremoris SK11	LACR_0248	-91	4.5	TTGTGATATAATTAACCT
Lactococcus lactis subsp. lactis Il1403	L0010	-91	4.5	TTGTGATATAATTAACCT
Streptococcus agalactiae 2603V/R	SAG1766	-84	4.7	TTGTGAAAAAGTAATCAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0272	-96	4.3	TTGTGAAATAGTTAATTT
Streptococcus gallolyticus UCN34	GALLO_1995	-137	4.4	TTGTAAAATGATACAGAA
		-47	4.5	TTGTGATATAATTAGCAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0209	-46	4.7	TTGTGATATAATTATCAT
Streptococcus mutans UA159	SMU.361	-47	4.7	TTGTGATATAATTATCAT
Streptococcus sanguinis SK36	SSA_0302	-87	4.5	TTGTGAAAATTTTCTTTA
Streptococcus suis 05ZYH33	SSU05_0157	-87	4.4	TTGTGAAAAAAATATCTT
Streptococcus uberis 0140J	SUB1629	-96	4.5	TTGTGAAAAAAATAATTT

Position: -134 Score: 4 Sequence: TTCTTAAAATAATTATAT Position: -81 Score: 4.7 Sequence: AAGTTAATCTTTTCACAA Locus tag: SmuNN2025_1590
	SmuNN2025_1590	-134	4	TTCTTAAAATAATTATAT
		-81	4.7	AAGTTAATCTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gap
Ortholog function: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Streptococcus agalactiae 2603V/R	SAG1768	-76	4.4	AAGTTAATCTTTTCACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1936	-78	4.7	AAGTTAATCTTTTCACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0207	-158	4	ATTTGAAAGAATGAACAA
Streptococcus mutans UA159	SMU.360	-81	4.7	AAGTTAATCTTTTCACAA
Streptococcus pyogenes M1 GAS	SPy0274	-79	4.7	AAGTTAATCTTTTCACAA
Streptococcus sanguinis SK36	SSA_2108	-157	4.8	TAGTGAAAGAATTCATAA
Streptococcus thermophilus CNRZ1066	str1788	-50	4.7	AAGTTAATCTTTTCACAA
Streptococcus uberis 0140J	SUB1630	-78	4.7	AAGTTAATCTTTTCACAA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of Rex regulog to Streptococcus mutans NN2025

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --