Propagation of MtaR regulog to Streptococcus pneumoniae 70585
| Source regulog: | MtaR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | LysR |
| Regulation mode: | repressor |
| Biological process: | Methionine metabolism |
| Effector: | Homocysteine |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus pneumoniae 70585 |
| Orthologous TF(s) | SP70585_0735 |
| Regulated genes | 7 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -99
Score: 6.5 Sequence: TATAGTTTTAAACTATA
Locus tag: SP70585_0223
|
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| SP70585_0223 | -99 | 6.5 | TATAGTTTTAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metQ | ||||
| Ortholog function: Methionine ABC transporter, substrate-binding protein | ||||
| Streptococcus mitis B6 | smi_1944 | -99 | 6.2 | TATAGCTTTAAACTATA |
| Streptococcus pneumoniae TIGR4 | SP_0149 | -99 | 6.5 | TATAGTTTTAAACTATA |
|
Position: -91
Score: 5.2 Sequence: TATAAGTTAAAACTATA
Locus tag: SP70585_0544
|
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| SP70585_0544 | -91 | 5.2 | TATAAGTTAAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: COG1912 | ||||
| Ortholog function: Conserved hypothetical protein | ||||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0468 | -30 | 4.5 | TAAAGTTCAGGACTATA |
| Streptococcus mitis B6 | smi_1812 | -91 | 4.6 | TATAAGGTAAAACTATA |
| Streptococcus mutans UA159 | SMU.1936c | -110 | 5.4 | TATAGGTAATAACTATA |
| Streptococcus pneumoniae TIGR4 | SP_0481 | -64 | 4.6 | TATAAGGTAAAACTATA |
| Streptococcus thermophilus CNRZ1066 | str0304 | -100 | 4.5 | CATAGCCAAAGGCTATA |
| Streptococcus uberis 0140J | SUB0314 | -106 | 6.3 | TATAGTTTTAGACTATA |
|
Position: -99
Score: 6.4 Sequence: TATAGTTTCAAACTATA
Locus tag: SP70585_0650
|
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| SP70585_0650 | -99 | 6.4 | TATAGTTTCAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metE | ||||
| Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) | ||||
| Streptococcus agalactiae 2603V/R | SAG2049 | -132 | 6.5 | TATAGTTTAAAACTATA |
| Streptococcus gallolyticus UCN34 | GALLO_1316 | -170 | 6.3 | TATAGTTAAAAACTATA |
| -139 | 5.9 | TATAGCTAAAAACTATA | ||
| -36 | 5.2 | TATAGTTTAAAACTAAT | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0310 | -180 | 5.4 | TATAGTTTTTGATTATA |
| -97 | 5.9 | TATAGTTTTTGGCTATA | ||
| Streptococcus mitis B6 | smi_1600 | -99 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus mutans UA159 | SMU.873 | -186 | 5.6 | TATAGATGAAAACTATA |
| -155 | 6.1 | TATAGCTTAAAACTATA | ||
| Streptococcus pneumoniae TIGR4 | SP_0585 | -99 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus sanguinis SK36 | SSA_0416 | -180 | 4.8 | CATAATTTCTACCTATA |
| -97 | 6.3 | TATAGTTTTAGACTATA | ||
| Streptococcus suis 05ZYH33 | SSU05_1774 | -235 | 5.2 | CATAGATAAAATCTATA |
| -99 | 4.8 | TATAGTCAAAAGTTATA | ||
| Streptococcus thermophilus CNRZ1066 | str0785 | -130 | 5.9 | TATAGTTATTAGCTATA |
| -58 | 6.5 | TATAGTTTAAAACTATA | ||
|
Position: -77
Score: 6.2 Sequence: TATAGTTTGAAACTATA
Locus tag: SP70585_0862
|
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| SP70585_0862 | -77 | 6.2 | TATAGTTTGAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: folD | ||||
| Ortholog function: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | ||||
| Streptococcus mitis B6 | smi_0869 | -35 | 6.2 | TATAGTTTGAAACTATA |
| Streptococcus mutans UA159 | SMU.572 | -93 | 4.6 | TATAATATTTAAATATA |
| Streptococcus pneumoniae TIGR4 | SP_0825 | -98 | 6.3 | TATAGTTTAAAGCTATA |
|
Position: -156
Score: 6.4 Sequence: TATAGTTTCAAACTATA
Locus tag: SP70585_1275
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| SP70585_1275 | -156 | 6.4 | TATAGTTTCAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: fhs | ||||
| Ortholog function: Formate--tetrahydrofolate ligase (EC 6.3.4.3) | ||||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1210 | -42 | 4.8 | TTTTGTTATAATCTATA |
| Streptococcus mitis B6 | smi_1192 | -157 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus pneumoniae TIGR4 | SP_1229 | -156 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus uberis 0140J | SUB0942 | -129 | 4.6 | TAAAGATATACACTATA |
|
Position: -93
Score: 6.2 Sequence: TATAGTTTGAAACTATA
Locus tag: SP70585_1564
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| SP70585_1564 | -93 | 6.2 | TATAGTTTGAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metB | ||||
| Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1768 | -140 | 5.2 | TATAGTTTTTACTTATA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1636 | -101 | 6.1 | TATAGTTTCAGACTATA |
| Streptococcus mitis B6 | smi_1508 | -93 | 6.2 | TATAGTTTGAAACTATA |
| Streptococcus pneumoniae TIGR4 | SP_1525 | -93 | 6.2 | TATAGTTTGAAACTATA |
| Streptococcus sanguinis SK36 | SSA_1737 | -44 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus thermophilus CNRZ1066 | str0352 | -130 | 5.9 | TATAGTAATAAACTATA |
|
Position: -109
Score: 5.4 Sequence: TATAATTGAAAACTATA
Locus tag: SP70585_1617
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| SP70585_1617 | -109 | 5.4 | TATAATTGAAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metA | ||||
| Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_0824 | -105 | 5.9 | TATAGCTAAAAACTATA |
| -71 | 5.4 | TATAATTGAAAACTATA | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1002 | -97 | 5.6 | CATAGTTTCAGGCTATA |
| -63 | 5.4 | TATAATTGAAAACTATA | ||
| Streptococcus mutans UA159 | SMU.1466 | -102 | 5.3 | TATAGTTGGAACCTATA |
| -68 | 5.2 | TATATTTGATAACTATA | ||
| Streptococcus pneumoniae TIGR4 | SP_1576 | -109 | 5.4 | TATAATTGAAAACTATA |
| Streptococcus sanguinis SK36 | SSA_1420 | -145 | 5.8 | CATAGTTTCTAACTATA |
| -111 | 5.4 | TATAATTGAAAACTATA | ||
| Streptococcus thermophilus CNRZ1066 | str1222 | -103 | 5.6 | TATAGTTTAAAGTTATA |